This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Dantrium (Dantrolene) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (50)
Death (5)
Life Threatening Events (13)
Disability (1)
Reports by Reaction Type
Off Label Use (10),
Infusion Site Irritation (6),
Vomiting (6),
Acne (6),
Altered State of Consciousness (6),
Pyrexia (4),
Condition Aggravated (4),
Drug Ineffective (3),
Diplopia (3),
Eye Movement Disorder (3),
Blood Creatinine Increased (3),
Acute Respiratory Failure (3)
Below are a few examples of reports where side effects / adverse reactions may be related to Dantrium (Dantrolene). For a complete list or a specific selection of reports, please use the links above.
Possible Dantrium side effects in
Reported by a consumer/non-health professional from Japan on 2012-08-23
Patient:
Reactions: Off Label Use, Tachycardia
Drug(s) suspected as cause:
Famotidine
Dosage: unk
Administration route: Oral
Start date: 2010-01-01
End date: 2012-07-26
Dantrium
Dosage: unk
Administration route: Oral
Indication: Quadriplegia
Start date: 2010-01-01
End date: 2012-07-26
Other drugs received by patient: Corticosteroids (Unspecified)
Possible Dantrium side effects in
Reported by a consumer/non-health professional from Japan on 2012-08-23
Patient:
Reactions: Off Label Use, Vomiting
Drug(s) suspected as cause:
Dantrium
Dosage: 25 mg, tid
Administration route: Oral
Indication: Muscle Tightness
Start date: 2012-03-29
End date: 2012-05-10
Dantrium
Dosage: 125 mg, unk
Administration route: Oral
Start date: 2012-07-04
Famotidine
Dosage: 10 mg, bid
Administration route: Oral
Indication: Gastric Haemorrhage
Start date: 2012-04-05
Dantrium
Dosage: 125 mg, unk
Administration route: Oral
End date: 2012-06-28
Dantrium
Dosage: 100 mg, unk
Administration route: Oral
Start date: 2012-05-11
Dantrium
Dosage: 100 mg, unk
Administration route: Oral
Start date: 2012-06-29
End date: 2012-07-03
Other drugs received by patient: Clarith; Laxoberon; Mucodyne; Rizaben; Depakene; Enteronon R; Berachin
Possible Dantrium side effects in 59 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-17
Patient: 59 year old female, weighing 40.0 kg (88.0 pounds)
Reactions: Jaundice, Liver Disorder
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Dantrium
Administration route: Oral
End date: 2011-08-12
Pramipexole Dihydrochloride
Administration route: Oral
End date: 2011-08-05
Other drugs received by patient: Plavix; Atelec; Candesartan Cilexetil and Hydrochlorothiazide
Possible Dantrium side effects in
Reported by a consumer/non-health professional from Japan on 2012-08-10
Patient:
Reactions: Off Label Use, Vomiting, Gastrointestinal Haemorrhage
Drug(s) suspected as cause:
Famotidine
Dosage: 10 mg, bid
Administration route: Oral
Indication: Gastric Haemorrhage
Start date: 2012-04-05
Dantrium
Dosage: 125 mg, unk
Administration route: Oral
Start date: 2012-07-04
Dantrium
Dosage: 125 mg, unk
Administration route: Oral
End date: 2012-06-28
Dantrium
Dosage: 100 mg, unk
Administration route: Oral
Start date: 2012-06-29
End date: 2012-07-03
Dantrium
Dosage: 25 mg, tid
Administration route: Oral
Indication: Muscle Tightness
Start date: 2012-03-29
End date: 2012-05-10
Dantrium
Dosage: 100 mg, unk
Administration route: Oral
Start date: 2012-05-11
Other drugs received by patient: Mucodyne; Depakene; Berachin; Enteronon R; Rizaben; Laxoberon; Clarithromycin
Possible Dantrium side effects in female
Reported by a physician from Japan on 2012-08-07
Patient: female
Reactions: Atrioventricular Block Complete
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Dantrium
Other drugs received by patient: Dantrolene Sodium; Diazepam; Recomodulin; Lansoprazole; Unasyn; Omeprazole; Gasmotin
Possible Dantrium side effects in male
Reported by a physician from Netherlands on 2012-08-07
Patient: male, weighing 54.0 kg (118.8 pounds)
Reactions: Bradycardia, Blood Creatinine Increased
Drug(s) suspected as cause:
Dantrium
Other drugs received by patient: Forsenid; Lasix; Remitch; Warfarin Potassium; Nexium; Allegra; Allopurinol; Alfarol; Nespo; Sorbitol 50pc INJ
Possible Dantrium side effects in
Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-08-01
Patient:
Reactions: Toxic Epidermal Necrolysis, Stevens-Johnson Syndrome
Drug(s) suspected as cause:
Dantrium
Diazepam
Possible Dantrium side effects in 52 year old female
Reported by a pharmacist from Netherlands on 2012-07-25
Patient: 52 year old female
Reactions: Atrioventricular Block Complete
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dantrium
Possible Dantrium side effects in male
Reported by a consumer/non-health professional from Netherlands on 2012-07-02
Patient: male, weighing 54.0 kg (118.8 pounds)
Reactions: Bradycardia, Blood Creatinine Increased
Drug(s) suspected as cause:
Dantrium
Other drugs received by patient: Alfarol; Sorbitol 50pc INJ; Nexium; Remitch; Forsenid; Warfarin Potassium; Nespo; Lasix; Allegra; Allopurinol
Possible Dantrium side effects in 40 year old male
Reported by a physician from France on 2012-07-02
Patient: 40 year old male
Reactions: Acne
Drug(s) suspected as cause:
Soriatane
Administration route: Oral
Indication: Dermatosis
Start date: 2011-08-15
End date: 2011-12-13
Dantrium
Dosage: 300mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
End date: 2012-02-01
Trospium Chloride
Dosage: 40mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Sertraline Hydrochloride
Dosage: 1ud per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-01
Isotretinoin
Administration route: Oral
Indication: Acne
Start date: 2011-12-13
Baclofen
Dosage: 120mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Possible Dantrium side effects in 40 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-06-22
Patient: 40 year old male
Reactions: Acne
Drug(s) suspected as cause:
Baclofen
Dosage: 120 mg, qd
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Trospium Chloride
Dosage: 2 x 20 mg, qd
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Dantrium
Dosage: 3 x 1 df, qd
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
End date: 2012-02-01
Possible Dantrium side effects in 48 year old male
Reported by a physician from Japan on 2012-06-15
Patient: 48 year old male
Reactions: Atelectasis, Dyspnoea, Respiratory Failure, Hypercapnia, Respiratory Fatigue, Sputum Retention, Vital Capacity Decreased
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Botox
Dosage: 240 units, single
Indication: Scoliosis
Start date: 2012-06-05
End date: 2012-06-05
Botox
Dosage: unk
Start date: 2006-12-14
End date: 2006-12-14
Lioresal
Administration route: Oral
Indication: Muscle Spasms
End date: 2012-06-07
Dantrium
Administration route: Oral
Indication: Muscle Spasms
End date: 2012-06-07
Diazepam
Administration route: Oral
Indication: Muscle Spasms
End date: 2012-06-07
Other drugs received by patient: Lansoprazole; Neuzym; Cefazolin Sodium; Mucosta; Mucodyne; Gasmotin; Hokunalin:tape; Sennoside
Possible Dantrium side effects in male
Reported by a consumer/non-health professional from Netherlands on 2012-06-08
Patient: male, weighing 54.0 kg (118.8 pounds)
Reactions: Bradycardia, Blood Creatinine Increased
Drug(s) suspected as cause:
Dantrium
Other drugs received by patient: Nexium; Alfarol; Remitch; Forsenid; Warfarin Potassium; Nespo; Lasix; Allegra; Sorbitol 50pc INJ; Allopurinol
Possible Dantrium side effects in 40 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-05-25
Patient: 40 year old male
Reactions: Acne
Drug(s) suspected as cause:
Sertraline Hydrochloride
Dosage: 1ud per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-01
Dantrium
Dosage: 300mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
End date: 2012-02-01
Baclofen
Dosage: 120mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Soriatane
Administration route: Oral
Indication: Dermatosis
Start date: 2011-08-15
End date: 2011-12-13
Isotretinoin
Administration route: Oral
Indication: Acne
Start date: 2011-12-13
Trospium Chloride
Dosage: 40mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Possible Dantrium side effects in 40 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-05-17
Patient: 40 year old male
Reactions: Acne
Drug(s) suspected as cause:
Trospium Chloride
Dosage: 2 x 20 mg, qd
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Dantrium
Dosage: 3 x 1 df, qd
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
End date: 2012-02-01
Baclofen
Dosage: 120 mg, qd
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Possible Dantrium side effects in 47 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-05-07
Patient: 47 year old male, weighing 79.0 kg (173.8 pounds)
Reactions: Withdrawal Syndrome, Neuroleptic Malignant Syndrome
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Pelex
Dosage: reg1:1g,tid;oral;13apr2012-15apr2012(3d);granules reg2:3gm,daily;oral 20apr2012-unk
Administration route: Oral
Indication: Nasopharyngitis
Start date: 2012-04-13
Calslot
Dosage: tabs
Administration route: Oral
Indication: Hypertension
Start date: 2011-12-26
Medicon
Dosage: tabs reg1:15mg,tid;oral;13apr2012-15apr2012 reg2:45mg,daily;oral;20apr2012-unk
Administration route: Oral
Indication: Nasopharyngitis
Start date: 2012-04-13
Brotizolam
Dosage: reg 2-0.5mg-15apr12-ong
Administration route: Oral
Indication: Insomnia
Start date: 2012-04-09
End date: 2012-04-15
Aripiprazole
Dosage: inj
Indication: Schizophrenia
Start date: 2011-12-12
End date: 2012-04-02
Potassium Chloride
Indication: Neuroleptic Malignant Syndrome
Start date: 2012-04-13
End date: 2012-04-15
Tathion
Dosage: injection
Indication: Neuroleptic Malignant Syndrome
Start date: 2012-04-13
End date: 2012-04-15
Diovan
Dosage: tabs
Administration route: Oral
Indication: Hypertension
Start date: 2011-05-09
Abilify
Dosage: 07aug07-26sep11;12mg,27sep11-02oct11;24mg,03oct11-12apr12;193d
Administration route: Oral
Indication: Schizophrenia
Start date: 2007-08-07
End date: 2012-04-12
NEO-Minophagen C
Indication: Neuroleptic Malignant Syndrome
Start date: 2012-04-13
End date: 2012-04-15
Dantrium
Dosage: reg 1 reg 2-16apr12-ong
Administration route: Oral
Indication: Neuroleptic Malignant Syndrome
Start date: 2012-04-13
End date: 2012-04-15
Placebo
Cefoperazone Sodium + Sulbactam Sodium
Indication: Neuroleptic Malignant Syndrome
Start date: 2012-04-13
End date: 2012-04-15
Mucosta
Dosage: tab
Administration route: Oral
Indication: Gastritis
Start date: 2006-03-22
End date: 2012-04-15
Other drugs received by patient: Livostin; Risperdal; Famotidine; Olopatadine HCL; Onon; Cleanal
Possible Dantrium side effects in male
Reported by a consumer/non-health professional from Netherlands on 2012-04-24
Patient: male
Reactions: Pyrexia
Drug(s) suspected as cause:
Dantrium
Other drugs received by patient: Diazepam; Sennoside; Akiriden; Valproate Sodium; Dantrium; Cellkam; Clonazepam; Nifedipine; Lithium Carbonate; Pentona; Lemonamin
Possible Dantrium side effects in 71 year old male
Reported by a consumer/non-health professional from Netherlands on 2012-04-23
Patient: 71 year old male, weighing 48.0 kg (105.6 pounds)
Reactions: Dyspnoea, Altered State of Consciousness
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Dantrium
Other drugs received by patient: Metformin HCL; Keishikashakuyakudaioutou; Metoprolol Tartrate; Daikentyuto; Rabeprazole Sodium; Kalimate; Magmitt; Cilnidipine; PL Gran.; Tizanidine HCL; Voglibose; Januvia; Aspirin
Possible Dantrium side effects in 40 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-04-19
Patient: 40 year old male
Reactions: Acne
Drug(s) suspected as cause:
Isotretinoin
Administration route: Oral
Indication: Acne
Start date: 2011-12-13
Sertraline Hydrochloride
Dosage: 1ud per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-01
Soriatane
Administration route: Oral
Indication: Dermatosis
Start date: 2011-08-15
End date: 2011-12-13
Trospium Chloride
Dosage: 40mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Baclofen
Dosage: 120mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Dantrium
Dosage: 300mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Possible Dantrium side effects in female
Reported by a consumer/non-health professional from Netherlands on 2012-04-17
Patient: female, weighing 48.4 kg (106.5 pounds)
Reactions: Drug Ineffective, Pyrexia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dantrium
Dosage: 20 mg, bid
Indication: Neuroleptic Malignant Syndrome
Start date: 2011-12-30
End date: 2012-01-05
Dantrium
Dosage: 25 mg, tid
Administration route: Oral
Start date: 2012-01-06
End date: 2012-01-08
Dantrium
Dosage: 20 mg, qd
Start date: 2012-01-08
End date: 2012-01-08
Dantrium
Dosage: 20 mg, tid
Start date: 2012-01-10
End date: 2012-01-10
Dantrium
Dosage: 25 mg, qd
Administration route: Oral
Start date: 2012-01-02
End date: 2012-01-02
Dantrium
Dosage: 20 mg, bid
Start date: 2012-01-09
End date: 2012-01-09
Other drugs received by patient: Phenobarbital TAB; Cefoperazone Sodium; Trihexyphenidyl HCL; Silece; Risperdal; Transfusion
Possible Dantrium side effects in 40 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-04-13
Patient: 40 year old male
Reactions: Acne
Drug(s) suspected as cause:
Trospium Chloride
Dosage: 2 x 20 mg, qd
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Dantrium
Dosage: 3 x 1 df, qd
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Baclofen
Dosage: 120 mg, qd
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-01
Possible Dantrium side effects in 47 year old female
Reported by a physician from United States on 2012-04-05
Patient: 47 year old female
Reactions: Off Label Use, Vomiting, Nausea, Acute Respiratory Failure, Infusion Site Irritation
Drug(s) suspected as cause:
Dantrium
Possible Dantrium side effects in 50 year old female
Reported by a physician from United States on 2012-04-05
Patient: 50 year old female
Reactions: Off Label Use, Urinary Tract Infection, Acute Myocardial Infarction, Infusion Site Irritation
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Dantrium
Possible Dantrium side effects in male
Reported by a consumer/non-health professional from Netherlands on 2012-04-02
Patient: male
Reactions: Disseminated Intravascular Coagulation, Platelet Count Decreased
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Dantrium
Other drugs received by patient: Probitor; Methylprednisolone Sodium Succinate; Clindamycin; Dopaston; Ceftazidime
Possible Dantrium side effects in male
Reported by a pharmacist from United States on 2012-03-28
Patient: male
Reactions: Thrombophlebitis
Drug(s) suspected as cause:
Dantrium
Possible Dantrium side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-28
Patient: female
Reactions: NO Adverse Event, Accidental Exposure
Drug(s) suspected as cause:
Dantrium
Possible Dantrium side effects in male
Reported by a pharmacist from United States on 2012-03-28
Patient: male
Reactions: Off Label Use, Infusion Site Necrosis
Drug(s) suspected as cause:
Dantrium
Dosage: 75 mg, every 6 hours
Indication: Neuroleptic Malignant Syndrome
Dantrium
Dosage: 150 mg, every 6 hours
Indication: Off Label Use
Possible Dantrium side effects in 71 year old male
Reported by a consumer/non-health professional from Netherlands on 2012-03-28
Patient: 71 year old male
Reactions: Dyspnoea, Altered State of Consciousness
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Dantrium
Other drugs received by patient: Metformin HCL; Metoprolol Tartrate; Keishikashakuyakudaioutou; Aspirin; Rabeprazole Sodium; PL Gran.; Tizanidine HCL; Voglibose; Cilnidipine; Daikentyuto; Januvia; Kalimate; Magmitt
Possible Dantrium side effects in female
Reported by a consumer/non-health professional from Netherlands on 2012-03-23
Patient: female, weighing 48.4 kg (106.5 pounds)
Reactions: Drug Ineffective, Pyrexia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dantrium
Dosage: 20 mg, bid
Start date: 2012-01-09
End date: 2012-01-09
Dantrium
Dosage: 20 mg, qd
Start date: 2012-01-08
End date: 2012-01-08
Dantrium
Dosage: 20 mg, tid
Start date: 2012-01-10
End date: 2012-01-10
Dantrium
Dosage: 25 mg, qd
Administration route: Oral
Start date: 2012-01-02
End date: 2012-01-02
Dantrium
Dosage: 20 mg, bid
Indication: Neuroleptic Malignant Syndrome
Start date: 2011-12-30
End date: 2012-01-05
Dantrium
Dosage: 25 mg, tid
Administration route: Oral
Start date: 2012-01-06
End date: 2012-01-08
Other drugs received by patient: Trihexyphenidyl HCL; Silece; Cefoperazone Sodium; Risperdal; Phenobarbital TAB; Transfusion
Possible Dantrium side effects in male
Reported by a consumer/non-health professional from Netherlands on 2012-02-27
Patient: male
Reactions: Pneumonia, Disseminated Intravascular Coagulation, Platelet Count Decreased
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Dantrium
Other drugs received by patient: Methylprednisolone Sodium Succinate; Dopaston; Clindamycin; Ceftazidime
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