Index of reports
> Cases with Pancytopenia (11)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cytoxan (Cyclophosphamide) where reactions include pancytopenia. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Cytoxan side effects in male
Reported by a consumer/non-health professional from United States on 2012-05-25
Patient: male, weighing 21.3 kg (46.9 pounds)
Reactions: B-Cell Lymphoma, Hypotension, Alanine Aminotransferase Increased, Pancytopenia, Roseolovirus Test Positive, Aspartate Aminotransferase Increased, Venoocclusive Liver Disease, Acute Respiratory Distress Syndrome, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Mesna
Indication: Product Used FOR Unknown Indication
Fludarabine Phosphate
Indication: Product Used FOR Unknown Indication
Velcade
Dosage: 1.3 mg/m2, cyclic
Indication: B-Cell Lymphoma
Start date: 2011-12-27
End date: 2012-01-06
Cytoxan
Indication: Product Used FOR Unknown Indication
Possible Cytoxan side effects in female
Reported by a physician from United States on 2012-05-23
Patient: female, weighing 85.0 kg (187.0 pounds)
Reactions: Vomiting, Urinary Tract Infection, Pancytopenia, Clostridium Difficile Colitis, Dysfunctional Uterine Bleeding, Pelvic Pain, Fall, Decubitus Ulcer, Metastases To Bone, Renal Failure Acute
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Velcade
Dosage: 2.7 mg, cyclic
Indication: Multiple Myeloma
Start date: 2011-11-08
End date: 2012-02-24
Velcade
Dosage: 2.7 mg, cyclic
Start date: 2012-05-01
Decadron
Dosage: 40 mg, cyclic
Administration route: Oral
Start date: 2012-05-01
Cytoxan
Decadron
Dosage: 40 mg, cyclic
Administration route: Oral
Indication: Multiple Myeloma
Cytoxan
Indication: Multiple Myeloma
Other drugs received by patient: Peridex / 00133002 /; Neurontin; Oxycodone Hydrochloride; Protonix; Antibiotics; Potassium Chloride; Oxycodone and Acetaminophen
Possible Cytoxan side effects in 49 year old female
Reported by a health professional (non-physician/pharmacist) from Taiwan, Province of China on 2012-05-18
Patient: 49 year old female
Reactions: Pneumonia, Anaemia, Pancytopenia, Pyrexia, B Precursor Type Acute Leukaemia, Multi-Organ Failure, Death, Lymphocytosis, Dizziness, Asthenia, Septic Shock, Leukocytosis, Decreased Appetite
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Cytoxan
Dosage: 100 mg, unk
Indication: Breast Cancer Stage II
Start date: 2008-03-01
Epirubicin
Indication: Breast Cancer Stage II
Start date: 2008-03-01
Fluorouracil
Indication: Breast Cancer Stage II
Start date: 2008-03-01
Possible Cytoxan side effects in female
Reported by a physician from United States on 2012-05-18
Patient: female, weighing 94.2 kg (207.2 pounds)
Reactions: Confusional State, Hepatic Function Abnormal, Unresponsive To Stimuli, Post Procedural Complication, Tachycardia, Aphasia, Musculoskeletal Stiffness, Pathogen Resistance, Lethargy, Crying, Febrile Neutropenia, Pancytopenia, Meningism, Computerised Tomogram Abnormal, Dysarthria, Activities of Daily Living Impaired, Enterococcus Test Positive, Pancreatitis, Hypertension, Asthenia, Intracranial Hypotension
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Methotrexate
Dosage: 45 mg
Cytoxan
Dosage: 2000 mg
Cytarabine
Dosage: 1200 mg
Mercaptopurine
Dosage: 1750 mg
Vincristine Sulfate
Dosage: 2 mg
Possible Cytoxan side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-07
Patient: female, weighing 85.0 kg (187.0 pounds)
Reactions: Vomiting, Urinary Tract Infection, Pancytopenia, Clostridium Difficile Colitis, Dysfunctional Uterine Bleeding, Pelvic Pain, Fall, Decubitus Ulcer, Metastases To Bone, Renal Failure Acute
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Decadron
Dosage: 40 mg, cyclic
Administration route: Oral
Indication: Multiple Myeloma
Velcade
Dosage: 2.7 mg, cyclic
Indication: Multiple Myeloma
Start date: 2011-11-08
End date: 2012-02-24
Cytoxan
Indication: Multiple Myeloma
Other drugs received by patient: Antibiotics; Protonix; Peridex / 00133002 /; Oxycodone and Acetaminophen; Oxycodone HCL; Neurontin; Potassium Chloride
Possible Cytoxan side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-24
Patient: male, weighing 58.0 kg (127.6 pounds)
Reactions: Vomiting, Nausea, Hypotension, Candida Sepsis, Pancytopenia, Multi-Organ Failure, Small Intestinal Obstruction, Dehydration, Pulmonary Oedema, Pleural Effusion
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Cytoxan
Dosage: 350 milligram
Administration route: Oral
Indication: Amyloidosis
Start date: 2008-08-28
End date: 2009-08-10
Dexamethasone
Dosage: 40 milligram
Revlimid
Dosage: 15 milligram
Administration route: Oral
Indication: Amyloidosis
Start date: 2008-08-28
End date: 2009-08-10
Cytoxan
Dosage: 300 milligram/sq. meter
Administration route: Oral
Avastin
Indication: Pleural Effusion
Dexamethasone
Dosage: 20 milligram
Indication: Amyloidosis
Start date: 2008-08-28
End date: 2009-08-10
Other drugs received by patient: Aldactone; Lasix; Nitroglycerin; Dobutamine HCL; RED Blood Cells; Crestor; Neupogen; Colace; Zetia; Acyclovir; Aspirin; Multi-Vitamin; Platelets; Ambien; Neupogen; Bactrim; Xopenex HFA; Zosyn; Phenylephrine HCL
Possible Cytoxan side effects in 81 year old female
Reported by a consumer/non-health professional from United States on 2012-04-10
Patient: 81 year old female
Reactions: Small Intestinal Obstruction, Herpes Simplex, Urinary Tract Infection Fungal, Febrile Neutropenia, Pancytopenia, Electrolyte Imbalance, Enteritis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cytoxan
Indication: B-Cell Small Lymphocytic Lymphoma
Start date: 2011-11-18
End date: 2012-01-16
Rituximab
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-11-18
End date: 2012-01-16
Dexamethasone
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-11-18
End date: 2012-01-16
Vincristine
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-11-18
End date: 2012-01-16
Rituximab
Indication: B-Cell Small Lymphocytic Lymphoma
Start date: 2011-11-18
End date: 2012-01-16
Dexamethasone
Indication: B-Cell Small Lymphocytic Lymphoma
Start date: 2011-11-18
End date: 2012-01-16
Cytoxan
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-11-18
End date: 2012-01-16
Vincristine
Indication: B-Cell Small Lymphocytic Lymphoma
Start date: 2011-11-18
End date: 2012-01-16
Possible Cytoxan side effects in 75 year old female
Reported by a physician from United States on 2012-03-23
Patient: 75 year old female
Reactions: Pancytopenia, Light Chain Analysis Increased
Drug(s) suspected as cause:
Revlimid
Dosage: 10 mg, 1 ub 1 d, po; 5-10mg, daily, po, 10 mg, 1 in 1 d, po
Administration route: Oral
Indication: Multiple Myeloma
Start date: 2010-05-01
End date: 2011-02-10
Revlimid
Dosage: 10 mg, 1 ub 1 d, po; 5-10mg, daily, po, 10 mg, 1 in 1 d, po
Administration route: Oral
Indication: Multiple Myeloma
Start date: 2009-06-01
End date: 2009-01-01
Revlimid
Dosage: 10 mg, 1 ub 1 d, po; 5-10mg, daily, po, 10 mg, 1 in 1 d, po
Administration route: Oral
Indication: Multiple Myeloma
Start date: 2009-09-01
End date: 2010-01-01
Cytoxan
Indication: Multiple Myeloma
Start date: 2011-01-01
End date: 2011-01-01
Other drugs received by patient: Velcade; Prednisone TAB
Possible Cytoxan side effects in 58 year old female
Reported by a consumer/non-health professional from United States on 2011-11-23
Patient: 58 year old female
Reactions: Tumour Lysis Syndrome, Urinary Tract Infection, Pancytopenia, Febrile Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cytoxan
Dosage: d1-3. q28d
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-07-26
End date: 2011-07-26
Fludarabine Phosphate
Dosage: d1-3.q28d
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-07-26
End date: 2011-07-26
Rituxan
Dosage: d1 q28d
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-07-26
End date: 2011-07-26
Possible Cytoxan side effects in 46 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-17
Patient: 46 year old female
Reactions: Plasmacytoma, Pancytopenia, Cardiomyopathy
Drug(s) suspected as cause:
Revlimid
Dosage: caps; 17aug09 to 29dec09(134d) 21sep2010 to unk(15mg);last dose:02dec2010
Administration route: Oral
Indication: Multiple Myeloma
Start date: 2009-08-17
Etoposide
Start date: 2010-01-08
Platinol
Start date: 2010-01-08
Cytoxan
Indication: Multiple Myeloma
Start date: 2010-09-21
Velcade
Indication: Multiple Myeloma
Start date: 2009-08-17
End date: 2009-12-29
Adriamycin PFS
Start date: 2010-01-08
Dexamethasone
Dosage: 17aug09 to 29dec09(134d) 21sep2010 to unk
Indication: Multiple Myeloma
Start date: 2009-08-17
Possible Cytoxan side effects in 76 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-28
Patient: 76 year old female, weighing 66.0 kg (145.2 pounds)
Reactions: Pancytopenia, Pyrexia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cytoxan
Dosage: 1 2 3 qcycle
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-04-19
End date: 2011-06-22
Cytoxan
Dosage: 1 2 3 qcycle
Indication: B-Cell Small Lymphocytic Lymphoma
Start date: 2011-04-19
End date: 2011-06-22
Rituxan
Dosage: 1 2 3 qcycle
Indication: B-Cell Small Lymphocytic Lymphoma
Start date: 2011-04-19
End date: 2011-06-21
Fludarabine Phosphate
Dosage: 1 2 3 qcycle
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-04-19
End date: 2011-06-22
Fludarabine Phosphate
Dosage: 1 2 3 qcycle
Indication: B-Cell Small Lymphocytic Lymphoma
Start date: 2011-04-19
End date: 2011-06-22
Rituxan
Dosage: 1 2 3 qcycle
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-04-19
End date: 2011-06-21
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