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Cytoxan (Cyclophosphamide) - Neutropenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Neutropenia (9)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cytoxan (Cyclophosphamide) where reactions include neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Cytoxan side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24

Patient: female

Reactions: Pneumocystis Jiroveci Pneumonia, Maternal Exposure During Pregnancy, Neutropenia, Premature Labour

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: Breast Cancer Stage II

Paclitaxel
    Indication: Breast Cancer Stage II

Cytoxan
    Indication: Breast Cancer Stage II



Possible Cytoxan side effects in female

Reported by a physician from Italy on 2012-06-06

Patient: female, weighing 45.5 kg (100.1 pounds)

Reactions: Platelet Count Decreased, Neutropenia, Neutrophil Count Decreased, Streptococcal Infection, Pneumonitis, Hypertransaminasaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisolone
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-14
    End date: 2011-11-18

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-14

Cytoxan
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-14

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-14



Possible Cytoxan side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-30

Patient: female

Reactions: Pneumonia, Neutropenia

Drug(s) suspected as cause:
Epirubicin Hydrochloride
    Dosage: unk

Cytoxan
    Dosage: unk



Possible Cytoxan side effects in 12 year old female

Reported by a physician from Argentina on 2012-05-25

Patient: 12 year old female

Reactions: Acute Lymphocytic Leukaemia, Neutropenia, Pyrexia

Adverse event resulted in: death

Drug(s) suspected as cause:
Etoposide
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-07-01

Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-07-01

Cytoxan
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-07-01



Possible Cytoxan side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-24

Patient:

Reactions: Neuropathy Peripheral, Neutropenia, Infusion Related Reaction, Infection

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 6-821 day cycles; n=28

Vincristine
    Indication: B-Cell Lymphoma

Doxorubicin HCL
    Dosage: 6-821 day cycles; n=28
    Indication: B-Cell Lymphoma

Obinutuzumab
    Indication: B-Cell Lymphoma

Cytoxan
    Indication: B-Cell Lymphoma

Prednisone
    Indication: B-Cell Lymphoma



Possible Cytoxan side effects in male

Reported by a physician from Germany on 2012-05-22

Patient: male

Reactions: Febrile Neutropenia, Skin Infection, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Neulasta
    Dosage: 6 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-06
    End date: 2012-04-20

Acyclovir
    Dosage: 400 mg, unk
    Administration route: Oral

Doxorubicin HCL
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Cytoxan
    Dosage: 1500 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Prednisolone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-21

Rituximab
    Dosage: 750 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-01
    End date: 2012-04-16

Other drugs received by patient: Acyclovir; Paspertin / 00041902 /; Metoclopramide; Rulid; Pantoprazole; Electrolytes NOS W / Macrogol 3350; Dipyrone TAB; MST / 00036302 /; Novalgin / 00169801 /



Possible Cytoxan side effects in male

Reported by a physician from Germany on 2012-05-18

Patient: male

Reactions: Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: 2 mg, qd
    Indication: B-Cell Lymphoma
    Start date: 2012-04-17
    End date: 2012-04-17

Cytoxan
    Dosage: 1600 mg, qd
    Indication: B-Cell Lymphoma
    Start date: 2012-04-17
    End date: 2012-04-17

Doxorubicin HCL
    Dosage: 100 mg, qd
    Indication: B-Cell Lymphoma
    Start date: 2012-04-17
    End date: 2012-04-17

Neulasta
    Dosage: 6 mg, qd
    Indication: B-Cell Lymphoma
    Start date: 2012-04-20
    End date: 2012-04-20

Rituximab
    Dosage: 750 mg, qd
    Indication: B-Cell Lymphoma
    Start date: 2012-04-16
    End date: 2012-04-16

Prednisolone
    Dosage: 50 mg, bid
    Administration route: Oral
    Indication: B-Cell Lymphoma
    Start date: 2012-04-16
    End date: 2012-04-21

Other drugs received by patient: Metoclopramide; Acyclovir; Pantoprazole; Dipyrone TAB; Morphine Sulfate



Possible Cytoxan side effects in 74 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-26

Patient: 74 year old male, weighing 81.2 kg (178.6 pounds)

Reactions: Excoriation, Anaemia, Hypotension, Neutropenic Sepsis, Tachycardia, Mental Status Changes, Atrial Fibrillation, Pyrexia, Fall, Cardiac Failure, Diarrhoea, Neutropenia, Cardiac Arrest, Lethargy, Cough

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Prednisone
    Administration route: Oral
    Start date: 2012-02-02
    End date: 2012-02-15

Lasix
    Indication: Cardiac Disorder
    End date: 2012-02-22

Matulane
    Administration route: Oral
    Start date: 2012-02-02
    End date: 2012-02-15

Spironolactone
    Indication: Cardiac Disorder
    End date: 2012-02-22

Coreg
    Indication: Cardiac Disorder
    End date: 2012-02-22

Cytoxan
    Start date: 2012-02-09
    End date: 2012-02-16

Lisinopril
    Indication: Cardiac Disorder
    End date: 2012-02-22

Vinblastine Sulfate
    Start date: 2012-02-09
    End date: 2012-02-16

Other drugs received by patient: Levofloxacin; Prevacid; Tamsulosin HCL; Klor-CON; Folic Acid; Multi-Vitamins; Bleomycin Sulfate; Dacarbazine; Lidocaine; Zofran; Doxorubicin HCL



Possible Cytoxan side effects in 48 year old female

Reported by a physician from United States on 2011-10-28

Patient: 48 year old female

Reactions: Renal Failure, Nausea, Mouth Ulceration, Anaemia, Squamous Cell Carcinoma of Skin, Neutropenia, Rash, Accidental Exposure

Drug(s) suspected as cause:
Dapsone
    Dosage: titrated up to 100 mg twice daily, titrated up to 50 mg daily
    Indication: Behcet's Syndrome

Arava
    Dosage: 20 mg daily
    Indication: Behcet's Syndrome

Imuran
    Dosage: titrated up to 150 mg daily
    Indication: Behcet's Syndrome

Plaquenil
    Dosage: 300 mg daily, 200 mg daily, 200 mg twice daily, oral
    Administration route: Oral
    Indication: Behcet's Syndrome

Enbrel
    Dosage: 25 mg twice weekly
    Indication: Behcet's Syndrome

Methotrexate
    Dosage: 7.5 mg per week, titrated up to 20 mg per week
    Indication: Behcet's Syndrome

Cytoxan
    Dosage: 250 mg, 250 mg, 500 mg, 750 mg, 1000 mg, 1250 mg, intravenous
    Indication: Behcet's Syndrome

Cyclosporine
    Indication: Behcet's Syndrome
    End date: 2001-01-06

Remicade
    Dosage: 200 mg, 300 mg, 400 mg, intravenous
    Indication: Behcet's Syndrome

Leukeran
    Dosage: titrated up to 4 mg daily, 3 mg daily, 3 mg daily
    Indication: Behcet's Syndrome

Colchicine
    Dosage: 6 mg twice daily, 6 mg twice daily
    Indication: Behcet's Syndrome

Cellcept
    Dosage: 1000 mg twice daily
    Indication: Behcet's Syndrome

Rituxan
    Dosage: 1000 mg, 1000 mg, intravenous
    Indication: Behcet's Syndrome
    End date: 2006-07-05

Prednisone
    Dosage: 10 mg daily
    Indication: Behcet's Syndrome

Other drugs received by patient: Terbutaline Sulfate; (Esomeprazole); Pregabalin; Acyclovir; (Fentanyl); Erythromycin; Sertraline Hydrochloride; Theophylline; Pentoxifylline; Furosemide; Folic Acid; Fluticasone Propionate / Salmeterol; Ipratropium Bromide and Albuterol Sulfate

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