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Cyclophosphamide (Cyclophosphamide) - Serious Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Serious Events (5315)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cyclophosphamide serious events. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 5315   Next >>

Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-27

Patient:

Reactions: Off Label Use, Gastrointestinal Toxicity, Neutropenia, Infection

Drug(s) suspected as cause:
Etoposide
    Indication: Retinoblastoma

Cyclophosphamide
    Indication: Retinoblastoma

Vincristine
    Dosage: 4 courses in intermediate risk and 6 courses in high risk
    Indication: Retinoblastoma

Carboplatin
    Dosage: 6 courses in high risk
    Indication: Retinoblastoma

Doxorubicin Hydrochloride
    Dosage: 4 courses in intermediate risk and 6 courses in high risk
    Indication: Retinoblastoma

Other drugs received by patient: Neupogen



Possible Cyclophosphamide side effects in female

Reported by a physician from United States on 2012-08-27

Patient: female, weighing 84.9 kg (186.8 pounds)

Reactions: Breast Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-06-15
    End date: 2012-08-01

Avastin
    Dosage: last dose prior to event - 27/jul/2012
    Indication: Breast Cancer
    Start date: 2012-06-15

Cyclophosphamide
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-06-15
    End date: 2012-08-01



Possible Cyclophosphamide side effects in 49 year old male

Reported by a physician from Norway on 2012-08-27

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Lung Infiltration, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Vincristine
    Dosage: on day 8
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Dosage: on day 8
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Doxorubicin Hydrochloride
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Prednisolone
    Dosage: on day 1 to 14 every 21 day cycle treatment for 6 cycles
    Administration route: Oral
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Dosage: on day 1,for standard cycles

Cyclophosphamide
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the standard cycles, day 1 to 3
    Indication: Hodgkin's Disease

Cyclophosphamide
    Dosage: for standard cycles on day 1

Procarbazine Hydrochloride
    Dosage: day 1 to 7
    Administration route: Oral
    Indication: Hodgkin's Disease



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-27

Patient: male

Reactions: Abscess Neck

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Velcade
    Dosage: unk
    Indication: Multiple Myeloma
    End date: 2011-06-21

Cisplatin
    Dosage: unk
    Indication: Multiple Myeloma
    End date: 2011-06-21

Doxorubicin Hydrochloride
    Dosage: unk
    Indication: Multiple Myeloma
    End date: 2011-06-21

Cyclophosphamide
    Dosage: unk
    Indication: Multiple Myeloma
    End date: 2011-06-21

Etoposide
    Dosage: unk
    Indication: Multiple Myeloma
    End date: 2011-06-21



Possible Cyclophosphamide side effects in 10 year old male

Reported by a physician from United States on 2012-08-27

Patient: 10 year old male, weighing 76.1 kg (167.4 pounds)

Reactions: Hypersensitivity, Hyperglycaemia, Peripheral Motor Neuropathy

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nelarabine
    Dosage: 650mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-05-22

Cytarabine
    Dosage: 75mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Mercaptopurine
    Dosage: 60mgm2 cyclic
    Administration route: Oral
    Indication: T-Cell Type Acute Leukaemia

PEG-Asparaginase
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-06-13

Methotrexate
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-06-06

Vincristine
    Dosage: 1.5mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-06-13

Cyclophosphamide
    Dosage: 1000mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Other drugs received by patient: Radiation



Possible Cyclophosphamide side effects in male

Reported by a physician from Netherlands on 2012-08-27

Patient: male, weighing 95.0 kg (209.0 pounds)

Reactions: Cranial Nerve Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rituximab
    Dosage: third maintenance cycle
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2010-09-06

Prednisone TAB
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: third maintenance cycle
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2010-09-06

Vincristine
    Dosage: third maintenance cycle
    Start date: 2010-09-06

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Dosage: third maintenance cycle
    Administration route: Oral
    Start date: 2010-09-06

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide

Neupogen
    Indication: Diffuse Large B-Cell Lymphoma

Neupogen
    Dosage: third maintenance cycle
    Start date: 2010-09-07

Doxorubicin HCL
    Dosage: third maintenance cycle
    Start date: 2010-09-06

Rituximab
    Start date: 2010-11-29
    End date: 2011-03-21



Possible Cyclophosphamide side effects in male

Reported by a physician from France on 2012-08-27

Patient: male

Reactions: Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-21
    End date: 2012-05-23

Prednisone TAB
    Administration route: Oral
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-20
    End date: 2012-05-24

Levoleucovorin Calcium
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-21
    End date: 2012-05-25

Doxorubicin Hydrochloride
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-21
    End date: 2012-05-21

Vincristine
    Start date: 2012-05-25

Mabthera
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-19
    End date: 2012-05-19

Vincristine
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-20

Methotrexate Disodium
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-20

Methotrexate Disodium
    Start date: 2012-05-25

Other drugs received by patient: Cytarabine; Calciparine; Ondansetron Hydrochloride; Allopurinol; Valaciclovir HCL; Nexium; Lyrica; Bactrim DS; Emend



Possible Cyclophosphamide side effects in

Reported by a physician from Germany on 2012-08-27

Patient:

Reactions: Acute Myeloid Leukaemia

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Chronic Lymphocytic Leukaemia

Fludarabine Phosphate
    Indication: Chronic Lymphocytic Leukaemia

Ofatumumab
    Indication: Chronic Lymphocytic Leukaemia



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-27

Patient: male, weighing 94.0 kg (206.8 pounds)

Reactions: Intussusception, Anaemia, Chronic Obstructive Pulmonary Disease, Renal Failure Chronic

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mabthera
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-08-16
    End date: 2012-01-03

Fludarabine Phosphate
    Dosage: day1, 2, 3 q month
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-08-16
    End date: 2012-01-05

Cyclophosphamide
    Dosage: day1, 2, 3 q month
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-08-16
    End date: 2012-01-05



Possible Cyclophosphamide side effects in female

Reported by a physician from Switzerland on 2012-08-27

Patient: female, weighing 87.7 kg (192.9 pounds)

Reactions: Cholecystitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-11

Rituximab
    Dosage: concentration 1/mg/ml
    Start date: 2011-11-11

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-11

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-11

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-11

Prednisolone
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-12

Other drugs received by patient: Pantoprazole; Exforge HCT; Dipyrone INJ; Bisoprolol Fumarate; Domperidon; Bactrim DS; Acetaminophen; Metformin Hydrochloride



Possible Cyclophosphamide side effects in 57 year old female

Reported by a physician from Croatia (Local Name: Hrvatska) on 2012-08-27

Patient: 57 year old female

Reactions: Breast Cancer Metastatic, Paraneoplastic Dermatomyositis, Pulmonary Embolism

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin Hydrochloride
    Dosage: 6 cycles
    Indication: Breast Cancer

Capecitabine
    Administration route: Oral
    Indication: Breast Cancer

Cisplatin
    Dosage: 6 cycles
    Indication: Breast Cancer

Gemcitabine Hydrochloride
    Indication: Breast Cancer

Paclitaxel
    Indication: Breast Cancer

Cyclophosphamide
    Dosage: 6 cycles
    Indication: Breast Cancer



Possible Cyclophosphamide side effects in 62 year old female

Reported by a physician from Spain on 2012-08-27

Patient: 62 year old female

Reactions: Osteonecrosis

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 600 mg/m2 q21d (4 cycles)
    Indication: Breast Cancer

Doxorubicin Hydrochloride
    Dosage: 60 mg/m2 q21d (4 cycles)
    Indication: Breast Cancer

Anastrozole
    Dosage: 1 mg/day
    Indication: Breast Cancer

Other drugs received by patient: Dexamethasone; Chlorhexidine Gluconate; Omeprazole



Possible Cyclophosphamide side effects in female

Reported by a physician from Italy on 2012-08-27

Patient: female, weighing 75.0 kg (165.0 pounds)

Reactions: Vomiting, Hypotension, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 600mgm2 cyclic
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-07-19

Losazid
    Dosage: 50mg twice per day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2009-03-29
    End date: 2012-07-25

Nipent
    Dosage: 2mgm2 cyclic
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-07-19

Arzerra
    Dosage: 300mg cyclic
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-07-20

Other drugs received by patient: Allopurinol; Sulfamethoxazole and Trimethoprim



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-27

Patient: male

Reactions: Dystonia, Encephalopathy, Parkinsonism

Drug(s) suspected as cause:
Vincristine

Cisplatin

Etoposide

Ifosfamide

Cyclophosphamide



Possible Cyclophosphamide side effects in 49 year old male

Reported by a physician from Norway on 2012-08-27

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Dosage: 10000 iu, day 8 (2 escalated cycles)
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Dosage: 100 mg/m2, day 1-7 (2 escalated cycles)
    Administration route: Oral
    Indication: Hodgkin's Disease

Vincristine
    Dosage: 1.4 mg/m2, day 8 (2 escalated cycles)
    Indication: Hodgkin's Disease

Cyclophosphamide
    Dosage: 650 mg/m2, day 1 (4 standard cycles)

Prednisolone
    Dosage: 40 mg/m2, day 1-14 (4 standard cycles)
    Administration route: Oral

Doxorubicin HCL
    Dosage: 25 mg/m2, day 1 (4 standard cycles)

Etoposide
    Dosage: 100 mg/m2, day 1-3 (4 standard cycles)

Procarbazine Hydrochloride
    Dosage: 100 mg/m2, day 1-7 (4 standard cycles)
    Administration route: Oral

Etoposide
    Dosage: 200 mg/m2, day 1-3 (2 escalated cycles)
    Indication: Hodgkin's Disease

Doxorubicin HCL
    Dosage: 35 mg/m2, day 1 (2 escalated cycles)
    Indication: Hodgkin's Disease

Prednisolone
    Dosage: 40 mg/m2, day 1-14 (2 escalated cycles)
    Administration route: Oral
    Indication: Hodgkin's Disease

Vincristine
    Dosage: 1.4 mg/m2, day 8 (4 standard cycles)

Bleomycin Sulfate
    Dosage: 10000 iu, day 8 (4 standard cycles)

Cyclophosphamide
    Dosage: 1250 mg/m2, day 1 (2 escalated cycles)
    Indication: Hodgkin's Disease



Possible Cyclophosphamide side effects in 79 year old female

Reported by a physician from Germany on 2012-08-27

Patient: 79 year old female

Reactions: Sciatica, Lumbar Vertebral Fracture

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mabthera
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Vincristine
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Doxorubicin Hydrochloride
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Prednisone
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive



Possible Cyclophosphamide side effects in 47 year old male

Reported by a physician from France on 2012-08-27

Patient: 47 year old male

Reactions: Respiratory Tract Infection Bacterial, Epstein-Barr Virus Associated Lymphoma, Congestive Cardiomyopathy, Systolic Dysfunction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisolone
    Administration route: Oral
    Start date: 2012-06-08

Nexium
    Administration route: Oral

Cyclophosphamide
    Start date: 2012-06-08

Doxorubicin HCL
    Start date: 2012-06-11
    End date: 2012-07-10

Mabthera
    Start date: 2012-06-11

Vincristine
    Start date: 2012-06-08

Other drugs received by patient: Previscan; Methotrexate Sodium; Potassium Chloride; Kineret; Kineret; Kineret; Cacit D3; Aspirin; Prednisone TAB; Acetaminophen; Acetaminophen W / Codeine; Alendronate Sodium / Cholecalciferol



Possible Cyclophosphamide side effects in female

Reported by a physician from Thailand on 2012-08-24

Patient: female, weighing 57.4 kg (126.3 pounds)

Reactions: Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Prednisone TAB
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Doxorubicin Hydrochloride
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Mabthera
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Cyclophosphamide
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Vincristine
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Other drugs received by patient: Dexamethasone; Acetaminophen; Ondansetron; Metformin HCL; Ondansetron; Ondansetron; Atenolol; Simvastatin; Benadryl



Possible Cyclophosphamide side effects in 51 year old male

Reported by a physician from Germany on 2012-08-24

Patient: 51 year old male

Reactions: Progressive Multifocal Leukoencephalopathy

Drug(s) suspected as cause:
Mabthera
    Indication: non-Hodgkin's Lymphoma

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma

Prednisone
    Indication: HIV Infection

Cyclophosphamide
    Indication: HIV Infection

Doxorubicin HCL
    Indication: HIV Infection

Mabthera
    Indication: HIV Infection

Vincristine
    Indication: HIV Infection

Prednisone TAB
    Indication: non-Hodgkin's Lymphoma

Doxorubicin HCL
    Indication: non-Hodgkin's Lymphoma

Vincristine
    Indication: non-Hodgkin's Lymphoma



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24

Patient: male, weighing 103.1 kg (226.8 pounds)

Reactions: Plasmacytosis, Pneumonia, Mouth Haemorrhage, Pseudomonas Infection, Headache, Disease Progression, Death, Mucosal Inflammation, Pleural Effusion, Depressed Level of Consciousness, Abscess, Lethargy, RIB Fracture

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Doxorubicin Hydrochloride
    Indication: Multiple Myeloma

Thalidomide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Radiation Therapy NOS
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma

Revlimid
    Indication: Multiple Myeloma

Dexamethasone
    Indication: Multiple Myeloma

Cisplatin
    Indication: Multiple Myeloma

Other drugs received by patient: Bendamustine Hydrochloride; Lenalidomide



Possible Cyclophosphamide side effects in female

Reported by a physician from Bulgaria on 2012-08-24

Patient: female, weighing 63.0 kg (138.6 pounds)

Reactions: Circulatory Collapse, Bone Marrow Failure

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1000 milligram
    Indication: Multiple Myeloma
    Start date: 2012-05-23
    End date: 2012-05-25

Doxorubicin Hydrochloride
    Dosage: 80 milligram
    Indication: Multiple Myeloma
    Start date: 2012-05-26
    End date: 2012-05-26

Dexamethasone
    Dosage: 40 milligram
    Start date: 2012-06-02
    End date: 2012-06-05

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-30
    End date: 2012-06-07

Dexamethasone
    Dosage: 40 milligram
    Indication: Multiple Myeloma
    Start date: 2012-05-23
    End date: 2012-05-26

Vincristine
    Dosage: 2 milligram
    Indication: Multiple Myeloma
    Start date: 2012-05-26
    End date: 2012-06-02

Dexamethasone
    Dosage: 20 milligram
    Start date: 2012-05-16
    End date: 2012-05-19

Other drugs received by patient: Milgamma; Dopamine HCL; Nexium; Atropine; Sodium Carbonate; Lyrica; Uromithexane; Electrolyte Infusions; Sodium Bicarbonate; Probitor; Tevagrastim



Possible Cyclophosphamide side effects in 65 year old female

Reported by a physician from Japan on 2012-08-24

Patient: 65 year old female, weighing 50.2 kg (110.6 pounds)

Reactions: Weight Decreased, Blood Bilirubin Increased, Cytomegalovirus Viraemia, Headache, Pyrexia, Interstitial Lung Disease, Oedema, Thrombocytopenia, Blood Sodium Decreased, Decreased Appetite, Vomiting, Stomatitis, Pneumonia, Alanine Aminotransferase Increased, Lymphopenia, Anaemia, Febrile Neutropenia, Rash, Blood Phosphorus Decreased, Blood Potassium Decreased, Diarrhoea, Alopecia, Aspartate Aminotransferase Increased, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Prednisolone
    Dosage: 1mg/kg x 1/2 week
    Start date: 2011-12-13
    End date: 2011-12-14

Adriamycin PFS
    Dosage: 30 mg/m2 x 1/4 week
    Start date: 2011-03-16

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Start date: 2011-03-16

Prednisolone
    Dosage: 2 mg/m2, 1x/day
    Administration route: Oral
    Start date: 2011-03-24

Vindesine Sulfate
    Dosage: 2.4 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Carboplatin
    Dosage: 250 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 350 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Etoposide
    Dosage: 100 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Vincristine Sulfate
    Dosage: 1 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Ranimustine
    Dosage: 60 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-16

Adriamycin PFS
    Dosage: 40 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Other drugs received by patient: Mucosolvan; Lansoprazole; Sulfamethoxazole and Trimethoprim; Armodafinil; Zolpidem; Olopatadine HCL; Cefazolin Sodium; Ciprofloxacin HCL; Armodafinil; Zovirax; Magmitt; Alendronate Sodium



Possible Cyclophosphamide side effects in male

Reported by a physician from Germany on 2012-08-24

Patient: male

Reactions: Febrile Neutropenia, Skin Infection, Neutropenia, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta
    Dosage: 6 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-06
    End date: 2012-04-20

Rituximab
    Dosage: 750 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-01
    End date: 2012-04-16

Cyclophosphamide
    Dosage: 1500 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Doxorubicin Hydrochloride
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Prednisolone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-21

Other drugs received by patient: MST / 00036302 /; Novalgin / 00169801 /; Rulid; Pantoprazole; Paspertin / 00041902 /; Acyclovir; Electrolytes NOS W / Macrogol 3350; Dipyrone INJ; Metoclopramide; Acyclovir



Possible Cyclophosphamide side effects in 52 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24

Patient: 52 year old female

Reactions: Tumour Lysis Syndrome, Posterior Reversible Encephalopathy Syndrome, Insomnia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Daunorubicin HCL
    Dosage: according to larson regimen
    Indication: B Precursor Type Acute Leukaemia

Methylprednisolone Sodium Succinate
    Indication: B Precursor Type Acute Leukaemia

Daunorubicin HCL
    Dosage: at 50% dosage

Prednisone TAB
    Dosage: according to larson regimen
    Indication: B Precursor Type Acute Leukaemia

Dexamethasone
    Indication: Premedication

Vincristine
    Dosage: according to larson regimen
    Indication: B Precursor Type Acute Leukaemia

Cyclophosphamide
    Dosage: according to larson regimen
    Indication: B Precursor Type Acute Leukaemia

Other drugs received by patient: Ondansetron; Voriconazole; Morphine Sulfate; Morphine



Possible Cyclophosphamide side effects in female

Reported by a physician from France on 2012-08-24

Patient: female

Reactions: Burning Sensation, Skin Exfoliation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mabthera
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-07-06
    End date: 2012-07-06

Fludarabine Phosphate
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-07-06
    End date: 2012-07-08

Cyclophosphamide
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-07-06
    End date: 2012-07-08



Possible Cyclophosphamide side effects in 64 year old male

Reported by a physician from Germany on 2012-08-24

Patient: 64 year old male, weighing 80.0 kg (176.0 pounds)

Reactions: Bacterial Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rituximab
    Start date: 2011-07-18

Fludarabine Phosphate
    Start date: 2011-07-19

Cyclophosphamide
    Start date: 2011-07-19

Other drugs received by patient: Prednisolone; Acyclovir



Possible Cyclophosphamide side effects in 49 year old male

Reported by a physician from Norway on 2012-08-24

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Lung Infiltration, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Dosage: on day 8
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Cyclophosphamide
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Cyclophosphamide
    Dosage: for standard cycles on day 1

Doxorubicin Hydrochloride
    Dosage: on day 1,for standard cycles

Vincristine
    Dosage: on day 8
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Dosage: day 1 to 7
    Administration route: Oral
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the standard cycles, day 1 to 3
    Indication: Hodgkin's Disease

Prednisolone
    Dosage: on day 1 to 14 every 21 day cycle treatment for 6 cycles
    Administration route: Oral
    Indication: Hodgkin's Disease



Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-24

Patient: male, weighing 26.9 kg (59.2 pounds)

Reactions: Tachycardia, Fungal Sepsis, Status Epilepticus, Oral Candidiasis, Hypomagnesaemia, Acute Respiratory Distress Syndrome, Bradycardia, Neutropenia, Blood Pressure Decreased, Shock

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Isotretinoin
    Dosage: 80 mg

C-CSF (Filgrastim, Amgen)
    Dosage: 135 mg

Vincristine Sulfate
    Dosage: 2.8 mg

Cisplatin
    Dosage: 74 mg

Cyclophosphamide
    Dosage: 1960 mg



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24

Patient: male, weighing 121.9 kg (268.2 pounds)

Reactions: Pruritus, Unresponsive To Stimuli, Device Related Infection, Pyrexia, Candidiasis, Abscess Limb, Ventricular Extrasystoles, Metabolic Acidosis, Dyspnoea, Hypotension, Pancytopenia, Tremor, Convulsion, Respiratory Failure, Fungal Infection, Ventricular Tachycardia, Sepsis, Respiratory Arrest, Pulse Absent, Sinus Tachycardia, Hypertension, Feeling Abnormal, Cardiac Arrest, Escherichia Infection, Infusion Related Reaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Epinephrine
    Dosage: 4 df, unk
    Indication: Cardiac Arrest
    Start date: 2012-07-14
    End date: 2012-07-14

Cyclophosphamide
    Dosage: daily for 5 days
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-19
    End date: 2012-06-23

Oncaspar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-07-02
    End date: 2012-07-02

Epinephrine
    Dosage: unk
    Start date: 2012-07-14
    End date: 2012-07-14

Clolar
    Dosage: 74.4 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-19
    End date: 2012-06-23

Etoposide
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-19
    End date: 2012-06-23

Vincristine Sulfate
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-07-02
    End date: 2012-07-02

Other drugs received by patient: Colace; Bactrim; Stomatitis Mouthwash; Prilosec; Lortab; Cymbalta; Ondansetron; Ambien



Possible Cyclophosphamide side effects in 52 year old female

Reported by a physician from United Kingdom on 2012-08-24

Patient: 52 year old female, weighing 83.3 kg (183.3 pounds)

Reactions: Neutropenic Sepsis, Pyrexia, Diarrhoea Infectious

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 500 mg/m2, every 3 weeks
    Indication: Breast Cancer
    Start date: 2012-07-02

Fluorouracil
    Dosage: 500 mg, every 3 weeks
    Indication: Breast Cancer
    Start date: 2012-07-02

Epirubicin Hydrochloride
    Dosage: 100 mg/m2, every 3 weeks
    Indication: Breast Cancer
    Start date: 2012-07-02

Fluorouracil
    Dosage: 1000 mg/m2, every 3 weeks

Pertuzumab
    Indication: Breast Cancer

Epirubicin Hydrochloride
    Dosage: 200 mg/m2, every 3 weeks

Cyclophosphamide
    Dosage: 1000 mg/m2, every 3 weeks

Trastuzumab
    Indication: Breast Cancer



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