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Cyclophosphamide (Cyclophosphamide) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (409)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cyclophosphamide life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 409   Next >>

Possible Cyclophosphamide side effects in

Reported by a physician from United States on 2012-08-23

Patient:

Reactions: Confusional State, White Blood Cell Count Decreased, Sepsis, Febrile Neutropenia, Encephalopathy, Platelet Count Decreased, Cystitis, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Blinded Vorinostat
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Cyclophosphamide
    Dosage: 750 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Placebo
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Prednisone TAB
    Dosage: 100 mg, qd, on days 3-7
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25
    End date: 2012-07-29

Rituximab
    Dosage: 375 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Simvastatin
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Simvastatin
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Vincristine Sulfate
    Dosage: 1.4 mg, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25



Possible Cyclophosphamide side effects in

Reported by a physician from United States on 2012-08-23

Patient:

Reactions: Confusional State, White Blood Cell Count Decreased, Sepsis, Febrile Neutropenia, Encephalopathy, Platelet Count Decreased, Cystitis, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Blinded Vorinostat
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Cyclophosphamide
    Dosage: 750 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Placebo
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Prednisone TAB
    Dosage: 100 mg, qd, on days 3-7
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25
    End date: 2012-07-29

Rituximab
    Dosage: 375 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Simvastatin
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Simvastatin
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Vincristine Sulfate
    Dosage: 1.4 mg, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25



Possible Cyclophosphamide side effects in

Reported by a physician from United States on 2012-08-23

Patient:

Reactions: White Blood Cell Count Decreased, Neutrophil Count Decreased, Hypokalaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Cisplatin
    Dosage: 3.5 mg/kg/day over 6 hours on day 4
    Start date: 2012-07-27

Cisplatin
    Dosage: 3.5 mg/kg/day over 6 hours on day 4
    Indication: Medulloblastoma
    Start date: 2012-07-26
    End date: 2012-07-26

Cisplatin
    Dosage: 3.5 mg/kg/day over 6 hours on day 4
    Start date: 2012-07-02
    End date: 2012-07-02

Cyclophosphamide
    Dosage: 60 mg/kg/day over 1 hour on day 5 and 6
    Indication: Medulloblastoma
    Start date: 2012-07-27
    End date: 2012-07-28

Cyclophosphamide
    Dosage: 60 mg/kg/day over 1 hour on day 5 and 6
    Start date: 2012-07-03
    End date: 2012-07-04

Etoposide
    Dosage: 2.5 mg/kg/day on days 4,5 and 6
    Start date: 2012-07-02
    End date: 2012-07-04

Etoposide
    Dosage: 2.5 mg/kg/day on days 4,5 and 6
    Start date: 2012-07-29

Etoposide
    Dosage: 2.5 mg/kg/day on days 4,5 and 6
    Indication: Medulloblastoma
    Start date: 2012-07-26
    End date: 2012-07-28

Furosemide
    Dosage: 5 mg, qd
    Start date: 2012-07-28
    End date: 2012-07-29

Isotretinoin
    Dosage: 80 mg/m2/dose, bid on days 1-4
    Administration route: Oral
    Indication: Medulloblastoma
    Start date: 2012-07-23
    End date: 2012-07-27

Isotretinoin
    Dosage: 80 mg/m2/dose, bid on days 1-4
    Administration route: Oral
    Start date: 2012-06-29

Vincristine
    Dosage: 0.05 mg/kg/day on days 4 11 and 18
    Start date: 2012-07-02

Vincristine
    Dosage: 0.05 mg/kg/day on days 4 11 and 18
    Indication: Medulloblastoma
    Start date: 2012-07-23

Vincristine
    Dosage: 0.05 mg/kg/day on days 4 11 and 18
    Start date: 2012-07-27

Vorinostat
    Dosage: 230 mg/m2/dose on days 1-4
    Administration route: Oral
    Start date: 2012-06-29

Vorinostat
    Dosage: 230 mg/m2/dose on days 1-4
    Administration route: Oral
    Indication: Medulloblastoma
    Start date: 2012-07-23
    End date: 2012-07-25



Possible Cyclophosphamide side effects in 75 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-21

Patient: 75 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Renal Impairment

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 500 milligram
    Administration route: Oral
    End date: 2012-06-26

Cyclophosphamide
    Dosage: 500 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-13

Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    End date: 2012-06-26

Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-13

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-13

Revlimid
    Administration route: Oral
    End date: 2012-06-26



Possible Cyclophosphamide side effects in 54 year old female

Reported by a physician from United States on 2012-08-21

Patient: 54 year old female, weighing 68.0 kg (149.6 pounds)

Reactions: White Blood Cell Count Decreased, Anaemia, Febrile Neutropenia, Pancytopenia, Platelet Count Decreased, Device Related Infection, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Dosage: 10 mg/kg, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Carboplatin
    Dosage: 6 df, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Cyclophosphamide
    Dosage: 600 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Doxorubicin HCL
    Dosage: 60 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Paclitaxel
    Dosage: 80 mg/m2, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Pegfilgrastim
    Dosage: 480 mug, unk
    Indication: Chemotherapy
    Start date: 2011-12-22

Other drugs received by patient: Tylenol (Caplet); Emend; Levaquin; Decadron; Zofran / 00955302 /; Aloxi; Compazine



Possible Cyclophosphamide side effects in

Reported by a physician from Germany on 2012-08-20

Patient:

Reactions: Infection

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: unk
    Indication: Multiple Myeloma
    Start date: 2012-03-26
    End date: 2012-07-05

Dexamethasone
    Dosage: unk
    Indication: Multiple Myeloma
    Start date: 2012-03-26
    End date: 2012-07-05

Velcade
    Dosage: unk
    Indication: Multiple Myeloma
    Start date: 2012-03-26
    End date: 2012-07-05

Other drugs received by patient: Zometa; Amoxicillin



Possible Cyclophosphamide side effects in female

Reported by a physician from Netherlands on 2012-08-16

Patient: female, weighing 7.4 kg (16.3 pounds)

Reactions: Capillary Leak Syndrome, Hepatic Function Abnormal, Respiratory Failure, Disease Progression, Ascites

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Clofarabine
    Dosage: 11 mg (40 mg/m2), qdx5
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-23
    End date: 2010-07-27

Cyclophosphamide
    Dosage: 80 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-23
    End date: 2010-07-27

Cytarabine
    Dosage: 15 mg, od
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-28
    End date: 2010-07-28

Cytarabine
    Indication: Chemotherapy

Etoposide
    Dosage: 28 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-23
    End date: 2010-07-27

Methotrexate
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: 6 mgr, od
    Indication: Chemotherapy
    Start date: 2010-07-28
    End date: 2010-07-28

Prednisolone
    Indication: Chemotherapy

Prednisolone
    Dosage: 6 mgr, od
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-28
    End date: 2010-07-28

Other drugs received by patient: Itraconazole; Vancomycin; Dexamethasone; Filgrastim; Teicoplanin; Ciprofloxacin HCL; Ciprofloxacin HCL; Tramadol HCL; Vancomycin; Ceftazidime; Zofran; Vancomycin; Furosemide; Cotrim; Vancomycin; Vitamin K TAB; Cotrim; Itraconazole; Vancomycin; Vancomycin; Omeprazole; Acetaminophen; Ciprofloxacin; Furosemide; Ceftazidime; Furosemide; Omeprazole



Possible Cyclophosphamide side effects in 74 year old female

Reported by a physician from United States on 2012-08-15

Patient: 74 year old female, weighing 72.0 kg (158.4 pounds)

Reactions: Myelodysplastic Syndrome

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 600 mg/m2 iv over 30 min, on day 1 q21 dayx 4, date of last drug taken prior to onset of ae:18/jun/2
    Indication: Breast Cancer
    Start date: 2002-04-08

Doxorubicin Hydrochloride
    Dosage: 60 mg/m2 intravenous push on day 1 every21 days x 4,date of last drug taken prior to onset of ae:18/
    Indication: Breast Cancer
    Start date: 2002-04-08

Herceptin
    Dosage: 4mg/kg over 90min (loading dose) on day1 of wk13 only,2mg/kg over 30 min (maintenance dose) qwk for
    Indication: Breast Cancer
    Start date: 2002-04-08

Paclitaxel
    Dosage: 175 mg/m2 over 3 hr q 21d starting day 1 of wk 13x 4, date of last drug taken prior to onset of ae:1
    Indication: Breast Cancer
    Start date: 2002-04-08



Possible Cyclophosphamide side effects in female

Reported by a physician from France on 2012-08-14

Patient: female, weighing 65.0 kg (143.0 pounds)

Reactions: Pulmonary Oedema, Myocardial Infarction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Cyclophosphamide
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Istodax
    Dosage: 22 milligram
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Prednisone TAB
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Vincristine
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Other drugs received by patient: Gemox



Possible Cyclophosphamide side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-14

Patient: female

Reactions: Circulatory Collapse

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Follicle Centre Lymphoma, Follicular Grade I, II, III Stage IV
    Start date: 2012-06-22

Doxorubicin Hydrochloride
    Indication: Follicle Centre Lymphoma, Follicular Grade I, II, III Stage IV
    Start date: 2012-06-22

Etoposide
    Indication: Follicle Centre Lymphoma, Follicular Grade I, II, III Stage IV
    Start date: 2012-06-22

Mabthera
    Indication: Follicle Centre Lymphoma, Follicular Grade I, II, III Stage IV
    Start date: 2012-06-22

Other drugs received by patient: Depamide; Rabeprazole Sodium



Possible Cyclophosphamide side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-13

Patient: 70 year old male

Reactions: Hypotension, Urosepsis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Administration route: Oral
    Start date: 2012-03-14
    End date: 2012-07-06

Dexamethasone
    Administration route: Oral
    Start date: 2012-03-14
    End date: 2012-07-06

Revlimid
    Administration route: Oral
    Start date: 2012-03-14
    End date: 2012-07-06



Possible Cyclophosphamide side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-13

Patient: female

Reactions: Septic Shock, Splenic Infarction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Nodal Marginal Zone B-Cell Lymphoma
    Start date: 2012-06-29
    End date: 2012-06-29

Prednisone TAB
    Dosage: 1 tablet
    Administration route: Oral
    Indication: Nodal Marginal Zone B-Cell Lymphoma
    Start date: 2012-06-28

Vincristine
    Dosage: 1 unit
    Indication: Nodal Marginal Zone B-Cell Lymphoma
    Start date: 2012-06-29
    End date: 2012-06-29

Other drugs received by patient: Aspirin; Acetaminophen; Fasturtec; Pravastatine Arrow; Venlafaxine; Potassium Chloride; Ramipril; Nexium; Bisoprolol Fumarate



Possible Cyclophosphamide side effects in 73 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-10

Patient: 73 year old female

Reactions: Neutropenic Sepsis, Sepsis

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-26
    End date: 2012-07-26

Dexamethasone
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-26
    End date: 2012-07-22

Revlimid
    Dosage: 10 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-26
    End date: 2012-07-01



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-09

Patient: male

Reactions: Diverticular Perforation

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 500 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-24
    End date: 2012-07-27

Dexamethasone
    Dosage: 40 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-24
    End date: 2012-07-27

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-24
    End date: 2012-07-27



Possible Cyclophosphamide side effects in male

Reported by a physician from Japan on 2012-08-09

Patient: male, weighing 57.0 kg (125.4 pounds)

Reactions: Cytomegalovirus Hepatitis, Cytomegalovirus Enterocolitis, Cytomegalovirus Chorioretinitis, Pancytopenia

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Histiocytosis Haematophagic

Cyclophosphamide
    Dosage: 1200 milligram daily;
    Indication: B-Cell Lymphoma
    Start date: 2011-09-27
    End date: 2011-10-17

Cyclosporine
    Administration route: Oral
    Indication: Histiocytosis Haematophagic
    Start date: 2011-09-26

Doxorubicin HCL
    Indication: Histiocytosis Haematophagic
    Start date: 2011-09-27

Etoposide
    Indication: Histiocytosis Haematophagic
    Start date: 2011-09-13

Prednisolone
    Dosage: 60 milligram daily;
    Administration route: Oral
    Indication: B-Cell Lymphoma
    Start date: 2011-09-09
    End date: 2011-10-17

Prednisolone
    Indication: Histiocytosis Haematophagic

Rituximab
    Indication: Histiocytosis Haematophagic
    Start date: 2011-04-13

Rituximab
    Dosage: cycle 3 % 4
    Indication: B-Cell Lymphoma
    Start date: 2011-05-25

Treanda
    Indication: B-Cell Lymphoma
    Start date: 2011-04-13

Vincristine Sulfate
    Indication: Histiocytosis Haematophagic

Vincristine Sulfate
    Dosage: 2 milligram daily;
    Indication: B-Cell Lymphoma
    Start date: 2011-09-27

Other drugs received by patient: Pirarubicin Hydrochloride



Possible Cyclophosphamide side effects in 60 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-09

Patient: 60 year old female

Reactions: Myelofibrosis, Acute Myeloid Leukaemia, Myelodysplastic Syndrome, Idiopathic Thrombocytopenic Purpura

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Alkeran
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Bicnu
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Cyclophosphamide
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: 4 years, intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Doxorubicin Hydrochloride
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Prednisone
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Velcade
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma
    Start date: 2008-05-05

Velcade
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma
    Start date: 2008-05-19

Velcade
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma
    Start date: 2008-04-08

Vepesid
    Dosage: intravenous (not otherwise sepcified)
    Indication: Multiple Myeloma

Vincristine Sulfate
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Other drugs received by patient: Neupogen; Corticosteroids



Possible Cyclophosphamide side effects in

Reported by a physician from United Kingdom on 2012-08-09

Patient:

Reactions: Small Intestinal Obstruction, Vomiting, Nausea, Abdominal Pain Upper

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1340 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Doxorubicin Hydrochloride
    Dosage: 90 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Prednisolone
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Rituximab
    Dosage: 670 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Velcade
    Dosage: 2.3 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-30
    End date: 2012-06-08

Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Other drugs received by patient: Acyclovir; Allopurinol; Amitriptyline HCL; Omeprazole; Amitriptyline HCL; Metoclopramide; Metoclopramide



Possible Cyclophosphamide side effects in female

Reported by a physician from United Kingdom on 2012-08-08

Patient: female, weighing 43.0 kg (94.6 pounds)

Reactions: Meningitis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-08
    End date: 2012-06-13

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-08
    End date: 2012-06-13

Prednisone TAB
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-07
    End date: 2012-06-13

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-08
    End date: 2012-06-13



Possible Cyclophosphamide side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-07

Patient: 70 year old male

Reactions: Hypotension, Urosepsis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Administration route: Oral
    Start date: 2012-03-14
    End date: 2012-07-06

Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    Start date: 2012-03-14
    End date: 2012-07-06

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Start date: 2012-03-14
    End date: 2012-07-06



Possible Cyclophosphamide side effects in male

Reported by a physician from France on 2012-08-07

Patient: male, weighing 67.0 kg (147.4 pounds)

Reactions: Myocardial Infarction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: Lymphoma
    Start date: 2012-07-05
    End date: 2012-07-05

Cyclophosphamide
    Indication: Lymphoma
    Start date: 2012-07-05
    End date: 2012-07-05

Istodax

Istodax
    Dosage: 21.6 milligram
    Indication: Lymphoma
    Start date: 2012-07-05
    End date: 2012-07-05

Oncovin
    Indication: Lymphoma
    Start date: 2012-07-05
    End date: 2012-07-05

Prednisone
    Indication: Lymphoma
    Start date: 2012-07-05
    End date: 2012-07-05



Possible Cyclophosphamide side effects in

Reported by a individual with unspecified qualification from United States on 2012-08-07

Patient:

Reactions: Lung Infection, Febrile Neutropenia, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: over 30-60 minutes on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-08

Cyclophosphamide
    Dosage: over 30-60 minutes on day 3
    Start date: 2012-07-12
    End date: 2012-07-12

Cyclophosphamide
    Dosage: over 30-60 minutes on day 3
    Start date: 2012-03-01
    End date: 2012-03-01

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, on day 3
    Start date: 2012-07-12
    End date: 2012-07-12

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, on day 3
    Start date: 2012-03-01
    End date: 2012-03-01

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-08

Prednisone
    Dosage: 100 mg, qd on days 3-7
    Administration route: Oral
    Start date: 2012-03-01
    End date: 2012-03-05

Prednisone
    Dosage: 100 mg, qd on days 3-7
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-12

Prednisone
    Dosage: 100 mg, qd on days 3-7
    Administration route: Oral
    Start date: 2012-07-12
    End date: 2012-07-12

Rituximab
    Dosage: 375 mg/m2, on day 3
    Start date: 2012-03-01
    End date: 2012-03-01

Rituximab
    Dosage: 375 mg/m2, on day 3
    Start date: 2012-07-12
    End date: 2012-07-12

Rituximab
    Dosage: 375 mg/m2, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-08

Vincristine Sulfate
    Dosage: 1.4 mg/m2, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-08

Vincristine Sulfate
    Dosage: 1.4 mg/m2, on day 3
    Start date: 2012-07-12
    End date: 2012-07-12

Vincristine Sulfate
    Dosage: 1.4 mg/m2, on day 3
    Start date: 2012-03-01
    End date: 2012-03-01

Vorinostat
    Dosage: on day 1-9
    Administration route: Oral
    Start date: 2012-02-28
    End date: 2012-03-07

Vorinostat
    Dosage: on day 1-9
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-06
    End date: 2012-02-14

Vorinostat
    Dosage: on day 1-5
    Administration route: Oral
    Start date: 2012-07-10
    End date: 2012-07-14



Possible Cyclophosphamide side effects in 49 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-03

Patient: 49 year old female

Reactions: Hepatitis B

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Administration route: Oral
    Start date: 2011-11-30
    End date: 2011-12-11

Cyclophosphamide
    Administration route: Oral
    Start date: 2011-11-23
    End date: 2011-11-30

Dexamethasone
    Administration route: Oral
    Start date: 2011-12-07
    End date: 2011-12-11

Dexamethasone
    Administration route: Oral
    Start date: 2011-11-23
    End date: 2011-12-07

Revlimid
    Administration route: Oral
    Start date: 2011-12-08
    End date: 2011-12-09

Revlimid
    Administration route: Oral
    Start date: 2011-11-23
    End date: 2011-12-08

Other drugs received by patient: Pamidronate Disodium



Possible Cyclophosphamide side effects in female

Reported by a physician from Japan on 2012-08-03

Patient: female, weighing 43.0 kg (94.6 pounds)

Reactions: Cystitis Haemorrhagic

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    End date: 2011-09-12

Halaven
    Indication: Breast Cancer Recurrent
    Start date: 2011-09-12

Halaven
    Indication: Metastases To Liver

Halaven
    Indication: Metastases To Bone

Other drugs received by patient: Prednisolone; Vitamin B12; Rabeprazole Sodium; Adenosine; Zometa



Possible Cyclophosphamide side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-01

Patient: female

Reactions: Acute Myeloid Leukaemia, Myelodysplastic Syndrome

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Alkeran
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Bicnu
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Cyclophosphamide
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Dexamethasone
    Start date: 2008-04-08

Dexamethasone
    Start date: 2008-06-01
    End date: 2008-01-01

Dexamethasone
    Indication: Multiple Myeloma
    Start date: 2008-05-05

Dexamethasone
    Start date: 2008-05-19

Doxorubicin Hydrochloride
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Prednisone
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Velcade
    Indication: Multiple Myeloma
    Start date: 2008-04-08
    End date: 2008-09-01

Vepesid
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Vincristine
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01



Possible Cyclophosphamide side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-01

Patient: female

Reactions: Acute Myeloid Leukaemia, Myelodysplastic Syndrome

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Alkeran
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Bicnu
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Cyclophosphamide
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Dexamethasone
    Indication: Multiple Myeloma
    Start date: 2004-01-01
    End date: 2008-01-01

Dexamethasone
    Start date: 2008-04-08
    End date: 2008-09-01

Doxorubicin Hydrochloride
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Prednisone
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Velcade
    Indication: Multiple Myeloma
    Start date: 2008-04-08
    End date: 2008-06-01

Vepesid
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Vincristine
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01



Possible Cyclophosphamide side effects in male

Reported by a physician from Sweden on 2012-07-31

Patient: male, weighing 64.0 kg (140.8 pounds)

Reactions: Adenoviral Hepatitis, Multi-Organ Failure, Acute Lymphocytic Leukaemia, Adenovirus Infection, Encephalitis

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Clofarabine
    Dosage: 40 mg/m2, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-10-24
    End date: 2011-10-28

Cyclophosphamide
    Dosage: 280 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-11-17
    End date: 2011-11-21

Etoposide
    Dosage: 80 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-11-17
    End date: 2011-11-21

Other drugs received by patient: Meropenem; Ambisome; Glucose; Betapred; Glucose; Valtrex



Possible Cyclophosphamide side effects in 75 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-31

Patient: 75 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Renal Impairment

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 500 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-13

Cyclophosphamide
    Dosage: 500 milligram
    Administration route: Oral
    End date: 2012-06-26

Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    End date: 2012-06-26

Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-13

Revlimid
    Administration route: Oral
    End date: 2012-06-26

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-13



Possible Cyclophosphamide side effects in female

Reported by a physician from France on 2012-07-31

Patient: female, weighing 65.0 kg (143.0 pounds)

Reactions: Pulmonary Oedema, Myocardial Infarction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Cyclophosphamide
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Istodax
    Dosage: 22 milligram
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Prednisone TAB
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Vincristine
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Other drugs received by patient: Gemox



Possible Cyclophosphamide side effects in

Reported by a physician from Netherlands on 2012-07-30

Patient:

Reactions: Diarrhoea, Pyrexia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1000 mg, unk
    Indication: Multiple Myeloma
    Start date: 2012-05-04
    End date: 2012-05-11

Dexamethasone
    Dosage: 40 mg, unk
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-04
    End date: 2012-05-15

Velcade
    Dosage: 2.6 mg, unk
    Indication: Multiple Myeloma
    Start date: 2012-05-04
    End date: 2012-05-14



Possible Cyclophosphamide side effects in

Reported by a physician from Korea, Republic of on 2012-07-30

Patient:

Reactions: Blood Bilirubin Increased, Hepatic Function Abnormal, Transaminases Increased, Disease Progression

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 750 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Doxil
    Dosage: 50 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Prednisone
    Dosage: 100 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-26

Velcade
    Dosage: 1.60 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Vincristine
    Dosage: 1.4 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22



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