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Cyclophosphamide (Cyclophosphamide) - Pyrexia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Pyrexia (278)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cyclophosphamide where reactions include pyrexia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 278   Next >>

Possible Cyclophosphamide side effects in 49 year old male

Reported by a physician from Norway on 2012-08-27

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Lung Infiltration, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Dosage: on day 8
    Indication: Hodgkin's Disease

Cyclophosphamide
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Cyclophosphamide
    Dosage: for standard cycles on day 1

Doxorubicin Hydrochloride
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Dosage: on day 1,for standard cycles

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Etoposide
    Dosage: for the standard cycles, day 1 to 3
    Indication: Hodgkin's Disease

Prednisolone
    Dosage: on day 1 to 14 every 21 day cycle treatment for 6 cycles
    Administration route: Oral
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Dosage: day 1 to 7
    Administration route: Oral
    Indication: Hodgkin's Disease

Vincristine
    Dosage: on day 8
    Indication: Hodgkin's Disease



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24

Patient: male, weighing 121.9 kg (268.2 pounds)

Reactions: Pruritus, Unresponsive To Stimuli, Device Related Infection, Pyrexia, Candidiasis, Abscess Limb, Ventricular Extrasystoles, Metabolic Acidosis, Dyspnoea, Hypotension, Pancytopenia, Tremor, Convulsion, Respiratory Failure, Fungal Infection, Ventricular Tachycardia, Sepsis, Respiratory Arrest, Pulse Absent, Sinus Tachycardia, Hypertension, Feeling Abnormal, Cardiac Arrest, Escherichia Infection, Infusion Related Reaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clolar
    Dosage: 74.4 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-19
    End date: 2012-06-23

Cyclophosphamide
    Dosage: daily for 5 days
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-19
    End date: 2012-06-23

Epinephrine
    Dosage: 4 df, unk
    Indication: Cardiac Arrest
    Start date: 2012-07-14
    End date: 2012-07-14

Epinephrine
    Dosage: unk
    Start date: 2012-07-14
    End date: 2012-07-14

Etoposide
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-19
    End date: 2012-06-23

Oncaspar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-07-02
    End date: 2012-07-02

Vincristine Sulfate
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-07-02
    End date: 2012-07-02

Other drugs received by patient: Colace; Bactrim; Stomatitis Mouthwash; Prilosec; Lortab; Cymbalta; Ondansetron; Ambien



Possible Cyclophosphamide side effects in 65 year old female

Reported by a physician from Japan on 2012-08-24

Patient: 65 year old female, weighing 50.2 kg (110.6 pounds)

Reactions: Weight Decreased, Blood Bilirubin Increased, Cytomegalovirus Viraemia, Headache, Pyrexia, Interstitial Lung Disease, Oedema, Thrombocytopenia, Blood Sodium Decreased, Decreased Appetite, Vomiting, Stomatitis, Pneumonia, Alanine Aminotransferase Increased, Lymphopenia, Anaemia, Febrile Neutropenia, Rash, Blood Phosphorus Decreased, Blood Potassium Decreased, Diarrhoea, Alopecia, Aspartate Aminotransferase Increased, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Dosage: 30 mg/m2 x 1/4 week
    Start date: 2011-03-16

Adriamycin PFS
    Dosage: 40 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Carboplatin
    Dosage: 250 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 350 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Etoposide
    Dosage: 100 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Prednisolone
    Dosage: 1mg/kg x 1/2 week
    Start date: 2011-12-13
    End date: 2011-12-14

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Start date: 2011-03-16

Prednisolone
    Dosage: 2 mg/m2, 1x/day
    Administration route: Oral
    Start date: 2011-03-24

Ranimustine
    Dosage: 60 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-16

Vincristine Sulfate
    Dosage: 1 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Vindesine Sulfate
    Dosage: 2.4 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Other drugs received by patient: Mucosolvan; Lansoprazole; Sulfamethoxazole and Trimethoprim; Armodafinil; Zolpidem; Olopatadine HCL; Cefazolin Sodium; Ciprofloxacin HCL; Armodafinil; Zovirax; Magmitt; Alendronate Sodium



Possible Cyclophosphamide side effects in 49 year old male

Reported by a physician from Norway on 2012-08-24

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Lung Infiltration, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Dosage: on day 8
    Indication: Hodgkin's Disease

Cyclophosphamide
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Cyclophosphamide
    Dosage: for standard cycles on day 1

Doxorubicin Hydrochloride
    Dosage: on day 1,for standard cycles

Doxorubicin Hydrochloride
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Etoposide
    Dosage: for the standard cycles, day 1 to 3
    Indication: Hodgkin's Disease

Prednisolone
    Dosage: on day 1 to 14 every 21 day cycle treatment for 6 cycles
    Administration route: Oral
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Dosage: day 1 to 7
    Administration route: Oral
    Indication: Hodgkin's Disease

Vincristine
    Dosage: on day 8
    Indication: Hodgkin's Disease



Possible Cyclophosphamide side effects in 52 year old female

Reported by a physician from United Kingdom on 2012-08-24

Patient: 52 year old female, weighing 83.3 kg (183.3 pounds)

Reactions: Neutropenic Sepsis, Pyrexia, Diarrhoea Infectious

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 500 mg/m2, every 3 weeks
    Indication: Breast Cancer
    Start date: 2012-07-02

Cyclophosphamide
    Dosage: 1000 mg/m2, every 3 weeks

Epirubicin Hydrochloride
    Dosage: 100 mg/m2, every 3 weeks
    Indication: Breast Cancer
    Start date: 2012-07-02

Epirubicin Hydrochloride
    Dosage: 200 mg/m2, every 3 weeks

Fluorouracil
    Dosage: 500 mg, every 3 weeks
    Indication: Breast Cancer
    Start date: 2012-07-02

Fluorouracil
    Dosage: 1000 mg/m2, every 3 weeks

Pertuzumab
    Indication: Breast Cancer

Trastuzumab
    Indication: Breast Cancer



Possible Cyclophosphamide side effects in female

Reported by a individual with unspecified qualification from United States on 2012-08-23

Patient: female, weighing 81.8 kg (180.0 pounds)

Reactions: Dyspnoea, Chest Pain, Pancytopenia, Pyrexia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1400 mg

Doxorubicin Hydrochloride
    Dosage: 94 mg

Prednisone
    Dosage: 375 mg

Rituximab (Moab C2b8 Anti Cd20, Chimeric)
    Dosage: 700 mg

Vincristine Sulfate
    Dosage: 2 mg



Possible Cyclophosphamide side effects in 49 year old male

Reported by a physician from Norway on 2012-08-23

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Septic Shock, Lung Infiltration

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Baxter 15 000 IE Lyofilisat TIL Injeksjonsv?ske / Infusjonsv?s

Cyclophosphamide

Cyclophosphamide

Doxorubicin Hydrochloride

Doxorubicin Hydrochloride

Etoposide

Etoposide

Prednisolone
    Administration route: Oral

Procarbazine Hydrochloride
    Administration route: Oral

Vincristine



Possible Cyclophosphamide side effects in female

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-08-23

Patient: female, weighing 52.0 kg (114.4 pounds)

Reactions: Graft Versus Host Disease, Staphylococcal Infection, Chills, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clofarabine
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Cyclophosphamide
    Dosage: 4380 mg, unk
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-11

Other drugs received by patient: Sulfamethoxazole Trimethoprim



Possible Cyclophosphamide side effects in male

Reported by a individual with unspecified qualification from United States on 2012-08-23

Patient: male, weighing 26.9 kg (59.2 pounds)

Reactions: Abdominal Pain, Dyspnoea, Dilatation Ventricular, Tachycardia, Fungal Sepsis, Status Epilepticus, Pyrexia, Hemiparesis, Breath Sounds Abnormal, Hypophagia, Hypomagnesaemia, Acute Respiratory Distress Syndrome, Shunt Malfunction, Neutropenia, Blood Pressure Decreased, Shock

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: 74 mg

Cyclophosphamide
    Dosage: 1960 mg

G-CSF (Filgrastim, Amgen)
    Dosage: 135 mg

Isotretinoin
    Dosage: 80 mg

Vincristine Sulfate
    Dosage: 2.8 mg



Possible Cyclophosphamide side effects in male

Reported by a consumer/non-health professional from France on 2012-08-23

Patient: male, weighing 79.0 kg (173.8 pounds)

Reactions: Abdominal Pain Lower, Bronchopulmonary Aspergillosis, Prostatitis, Cystitis Haemorrhagic, Human Polyomavirus Infection, Pyrexia, Dysuria, Adenovirus Infection, Pollakiuria

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Campath
    Dosage: 30 mg/m2, 3 times per 1 cycle
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2008-07-15
    End date: 2008-12-03

Cyclophosphamide
    Dosage: 500 mg/m2, unk
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2008-07-15
    End date: 2008-12-03

Fludara
    Dosage: 80 mg/m2, unk
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2008-07-15
    End date: 2008-12-03

Other drugs received by patient: Valganciclovir; Bactrim; Folic Acid; Vfend



Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-22

Patient: male, weighing 94.0 kg (206.8 pounds)

Reactions: Tachycardia, Clostridium Difficile Colitis, Pancytopenia, Neutropenia, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 2780 mg

Doxorubicin Hydrochloride
    Dosage: 152 mg

Etoposide
    Dosage: 720 mg

Fluorine-18 2-Fluorou-2 Deoxyry-D-Glucose (18f-Fdg)
    Dosage: 12 mg

Prednisone
    Dosage: 1300 mg

Rituximab
    Dosage: 800 mg

Vincristine Sulfate
    Dosage: 3.6 mg



Possible Cyclophosphamide side effects in male

Reported by a consumer/non-health professional from France on 2012-08-17

Patient: male, weighing 79.0 kg (173.8 pounds)

Reactions: Abdominal Pain Lower, Prostatitis, Adenovirus Infection, Dysuria, Cystitis Haemorrhagic, Pollakiuria, Human Polyomavirus Infection, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Campath
    Dosage: 30 mg/m2, 3 times per 1 cycle
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2008-07-15
    End date: 2008-12-03

Cyclophosphamide
    Dosage: 500 mg/m2, unk
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2008-07-15
    End date: 2008-12-03

Fludara
    Dosage: 80 mg/m2, unk
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2008-07-15
    End date: 2008-12-03

Other drugs received by patient: Valganciclovir; Vfend; Folic Acid; Bactrim



Possible Cyclophosphamide side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16

Patient: female, weighing 87.8 kg (193.2 pounds)

Reactions: Neuropathy Peripheral, Upper Respiratory Tract Infection, Urinary Tract Infection, Pleural Effusion, Pyrexia, Leukocytosis, Sinusitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Mantle Cell Lymphoma

Cytarabine
    Dosage: 1.87 g, cyclic
    Indication: Mantle Cell Lymphoma

Dexamethasone
    Dosage: 40 mg, unk
    Administration route: Oral
    Indication: Mantle Cell Lymphoma

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, unk
    Indication: Mantle Cell Lymphoma

Mesna
    Dosage: 600 mg/m2, unk
    Indication: Mantle Cell Lymphoma

Methotrexate
    Indication: Mantle Cell Lymphoma

Rituximab
    Dosage: 1 mg/m2, cyclic
    Indication: Mantle Cell Lymphoma

Velcade
    Dosage: 0.7 mg/m2, cyclic
    Start date: 2012-03-19

Velcade
    Dosage: 2.77 mg, cyclic
    Indication: Mantle Cell Lymphoma
    Start date: 2011-12-31

Velcade
    Dosage: 0.7 mg/m2, cyclic

Velcade
    Dosage: 0.7 mg/m2, cyclic
    Start date: 2012-02-26

Vincristine
    Dosage: 2 mg, cyclic
    Indication: Mantle Cell Lymphoma

Other drugs received by patient: Sennosides A+B; Nystatin; Diphenhydramine Hydrochloride; Neupogen; Fluconazole; Zofran; Valtrex; Sodium Chloride; Meperidine HCL; Potassium Chloride; Leucovorin Calcium; Zofran; Sodium Chloride; Sodium Chloride; Sodium Chloride; Heparin; Leucovorin Calcium; Allopurinol; Lovenox; Morphine; Senokot; Cipro / 00042702 /; Lovenox; Prednisolone Acetate; Stomatologicals, Mouth Preparations; Tramadol; Sodium Bicarbonate



Possible Cyclophosphamide side effects in 61 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: 61 year old female

Reactions: Mucosal Inflammation, Nausea, Pyrexia, Diffuse Large B-Cell Lymphoma Recurrent, Oral Herpes

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Etoposide
    Indication: Diffuse Large B-Cell Lymphoma

Methotrexate
    Indication: Diffuse Large B-Cell Lymphoma

Prednisolone
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-13

Patient: male, weighing 129.0 kg (283.8 pounds)

Reactions: Lung Disorder, Dyspnoea, Chills, Rhinorrhoea, Pyrexia, Hyperuricaemia, Oxygen Saturation Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1970 mg

Rituximab (Moab C2b8 Anti Cd20, Chimeric)
    Dosage: 990 mg

Vincristine Sulfate
    Dosage: 2 mg

Other drugs received by patient: Doxorubicin Hydrochloride



Possible Cyclophosphamide side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-10

Patient: female

Reactions: Acute Pulmonary Oedema, Weight Increased, Hypersensitivity, Skin Toxicity, Chills, Rash Papular, Crepitations, Pyrexia, Aplasia, Oxygen Saturation Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 2800 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2010-10-10
    End date: 2010-10-13

Cyclosporine
    Dosage: 200 mg, bid
    Administration route: Oral
    Indication: Immunosuppressant Drug Therapy
    Start date: 2010-08-11

Prednisone TAB
    Dosage: 56 mg, unk
    Indication: Immunosuppressant Drug Therapy
    Start date: 2010-08-16

Solu-Medrol
    Dosage: 11 mg, qd
    Indication: Immunosuppressant Drug Therapy
    Start date: 2010-08-11
    End date: 2010-08-15

Solu-Medrol
    Dosage: 100 mg, qid
    Start date: 2010-10-11
    End date: 2010-10-15

Thymoglobulin
    Dosage: 196 mg, qd
    Indication: Immunosuppression
    Start date: 2010-08-11
    End date: 2010-08-15

Thymoglobulin
    Dosage: 112 mg, qd
    Start date: 2010-10-11
    End date: 2010-10-13

Other drugs received by patient: Zovirax; Tazobactam; Vancomycin; Tazobactam



Possible Cyclophosphamide side effects in 46 year old female

Reported by a individual with unspecified qualification from United States on 2012-08-08

Patient: 46 year old female

Reactions: Dyspnoea, Pain in Extremity, Myelodysplastic Syndrome, General Physical Health Deterioration, Pyrexia, Pulmonary Haemorrhage, Zygomycosis, Diarrhoea, Skin Discolouration, Central Nervous System Infection, Small Intestinal Haemorrhage, Cough

Adverse event resulted in: death

Drug(s) suspected as cause:
Carmustine
    Indication: Diffuse Large B-Cell Lymphoma

Carmustine
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: 400 ug, intravenous, every two months
    Indication: Diffuse Large B-Cell Lymphoma

Cytarabine
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Idarubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Melphalan (Melphalan) (Melphalen)
    Indication: Diffuse Large B-Cell Lymphoma

Melphalan Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab (Rituximab) (Rituximab)
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab (Rituximab) (Rituximab)
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Cyclophosphamide side effects in 19 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-03

Patient: 19 year old female

Reactions: Dyspnoea, Pancytopenia, Pyrexia, Chronic Myeloid Leukaemia, Multi-Organ Failure, Fatigue, Neoplasm Malignant, Sepsis, Chest Pain

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Dosage: 8 consolidation cycles
    Indication: Medulloblastoma

Cyclophosphamide
    Dosage: 8 consolidation cycles
    Indication: Medulloblastoma

Vincristine Sulfate
    Dosage: weekly, followed by 8 consolidation cycles
    Indication: Medulloblastoma



Possible Cyclophosphamide side effects in 60 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-03

Patient: 60 year old female

Reactions: Vascular Occlusion, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-18
    End date: 2012-05-25

Dexamethasone
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-18
    End date: 2012-05-21

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-18
    End date: 2012-05-26



Possible Cyclophosphamide side effects in male

Reported by a individual with unspecified qualification from United States on 2012-08-02

Patient: male, weighing 85.9 kg (189.0 pounds)

Reactions: Penile Pain, Pyrexia, Erythema

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1635 mg

Doxorubicin Hydrochloride
    Dosage: 88 mg

Etoposide
    Dosage: 436 mg

Prednisone TAB
    Dosage: 650 mg

Rituximab (Moab C2b8 Anti Cd20, Chimeric)
    Dosage: 818 mg

Vincristine Sulfate
    Dosage: 3.48 mg



Possible Cyclophosphamide side effects in female

Reported by a physician from United States on 2012-07-31

Patient: female, weighing 50.3 kg (110.7 pounds)

Reactions: Blood Alkaline Phosphatase Increased, Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased, Epstein-Barr Virus Test Positive, Pyrexia

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1275 mg
    End date: 2012-05-16

Fludarabine Phosphate
    Dosage: 129 mg
    End date: 2012-05-16

Rituximab (Moab C2b8 Anti Cd20, Chimeric)
    Dosage: 850 mg
    End date: 2012-05-14



Possible Cyclophosphamide side effects in 46 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-30

Patient: 46 year old female

Reactions: Pain in Extremity, Anaemia, Pyrexia, Pallor, Stem Cell Transplant, Pulmonary Haemorrhage, Zygomycosis, Skin Discolouration, Blood Culture Positive, Diarrhoea Haemorrhagic, Small Intestinal Haemorrhage, Asthenia, Hepatosplenomegaly, Candidiasis, Cough

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carmustine

Cyclophosphamide
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Cytarabine

Cytarabine
    Dosage: 1.5 g/d/m2 (1 cycle)

Doxorubicin Hydrochloride
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Etoposide

Idarubicin HCL
    Dosage: 12 mg/d/m2 (1 cycle)

Melphalan Hydrochloride

Oncovin
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab

Vorinostat
    Dosage: 1 cycle
    Administration route: Oral



Possible Cyclophosphamide side effects in male

Reported by a physician from Poland on 2012-07-30

Patient: male, weighing 88.0 kg (193.6 pounds)

Reactions: Visual Impairment, Pyrexia, Lacrimation Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide

Other drugs received by patient: Zocor; Prednisone; Kalipoz; Furosemidum; Aspirin; Bisoprolol Fumarate; Nitrendypina; Ramipril; Anesteloc; Fragmin



Possible Cyclophosphamide side effects in

Reported by a physician from Netherlands on 2012-07-30

Patient:

Reactions: Diarrhoea, Pyrexia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1000 mg, unk
    Indication: Multiple Myeloma
    Start date: 2012-05-04
    End date: 2012-05-11

Dexamethasone
    Dosage: 40 mg, unk
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-04
    End date: 2012-05-15

Velcade
    Dosage: 2.6 mg, unk
    Indication: Multiple Myeloma
    Start date: 2012-05-04
    End date: 2012-05-14



Possible Cyclophosphamide side effects in 82 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-30

Patient: 82 year old female

Reactions: Confusional State, Pyrexia, Lymphoma

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: B-Cell Lymphoma

Mabthera
    Indication: B-Cell Lymphoma

Prednisolone
    Indication: B-Cell Lymphoma

Vincristine
    Indication: B-Cell Lymphoma

Other drugs received by patient: Methotrexate



Possible Cyclophosphamide side effects in 46 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-27

Patient: 46 year old female

Reactions: Pancreatic Infarction, Unresponsive To Stimuli, Myelodysplastic Syndrome, Pyrexia, Pallor, Cerebral Haemorrhage, Skin Discolouration, Diarrhoea Haemorrhagic, Small Intestinal Haemorrhage, Apnoea, Thrombocytopenia, Cough, Candidiasis, Hepatosplenomegaly, Dyspnoea, Pain in Extremity, Anaemia, Pulmonary Haemorrhage, Zygomycosis, Diarrhoea, Hemisensory Neglect, Lung Infiltration, Asthenia, Hepatic Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Carmustine
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Cytarabine
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Etoposide
    Indication: Diffuse Large B-Cell Lymphoma

Idarubicin HCL
    Dosage: 12 mg/m2, unk
    Indication: Myelodysplastic Syndrome

Oncovin
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma

Suberoylanilide Hydroxamic Acid
    Dosage: 500 mg, tid
    Administration route: Oral
    Indication: Myelodysplastic Syndrome

Other drugs received by patient: Radiotherapy



Possible Cyclophosphamide side effects in 33 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-25

Patient: 33 year old female

Reactions: Hyperbilirubinaemia, Enterococcal Infection, Pyrexia, Chorioretinitis, Large Intestinal Ulcer, Abdominal Distension, Microsporidia Infection, Hydrocephalus, Meningitis, Papule, Retinal Haemorrhage, Pulmonary Alveolar Haemorrhage, Hepatic Enzyme Increased, Respiratory Failure, Diarrhoea, Fungal Infection, Aspartate Aminotransferase Increased, Dermal Cyst, Lung Infiltration, Macule, Inflammation

Adverse event resulted in: death

Drug(s) suspected as cause:
Alemtuzumab
    Indication: Multiple Myeloma

Alemtuzumab
    Indication: Prophylaxis

Cyclophosphamide
    Indication: Multiple Myeloma

Cyclosporine
    Indication: Prophylaxis

Cyclosporine
    Indication: Stem Cell Transplant

Cyclosporine
    Dosage: unk
    Indication: Multiple Myeloma

Fludarabine Phosphate
    Dosage: unk
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in 57 year old male

Reported by a physician from France on 2012-07-23

Patient: 57 year old male

Reactions: Alanine Aminotransferase Increased, Hypercreatininaemia, Oedema Peripheral, Neutropenia, Pyrexia, Rash Maculo-Papular

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Start date: 2012-06-02
    End date: 2012-06-04

Cyclophosphamide
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-04-28
    End date: 2012-04-30

Fludarabine Phosphate
    Start date: 2012-06-02
    End date: 2012-06-04

Fludarabine Phosphate
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-04-28
    End date: 2012-04-30

Mabthera
    Start date: 2012-06-01
    End date: 2012-06-04

Mabthera
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-04-27
    End date: 2012-04-30

Other drugs received by patient: MAG 2; Valacyclovir Hydrochloride; Phosphoneuros; Dedrogyl; Bactrim DS; Difrarel 100; Escitalopram



Possible Cyclophosphamide side effects in 44 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-20

Patient: 44 year old female, weighing 55.5 kg (122.1 pounds)

Reactions: Abdominal Pain, Intestinal Ischaemia, Colitis Ischaemic, White Blood Cell Count Decreased, Vomiting, Blood Creatine Phosphokinase Increased, Gastrointestinal Necrosis, Pyrexia, Multi-Organ Failure, Diarrhoea, GAS Gangrene, Heart Rate Increased, Bone Marrow Failure, Neutropenia, Clostridial Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 7 cycles, total 4 courses
    Indication: Breast Cancer
    Start date: 2011-07-22
    End date: 2011-09-22

Epirubicin
    Dosage: 7 cycles, total 4 courses
    Indication: Breast Cancer
    Start date: 2011-07-22
    End date: 2011-09-22

Taxotere
    Dosage: 4 cycles, total 3 courses, dose taken once daily
    Indication: Breast Cancer
    Start date: 2011-10-14
    End date: 2011-11-25

Other drugs received by patient: Leucon; Lorazepam; Decadron Phosphate; Lorazepam; Kytril; Prochlorperazine; Kytril; Cepharanthin; Decadron Phosphate; Marzulene S



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-20

Patient: male

Reactions: Alanine Aminotransferase Increased, Oedema Peripheral, Neutropenia, Pyrexia, Rash Maculo-Papular, Blood Creatinine Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Administration route: Oral
    Start date: 2012-06-02
    End date: 2012-06-04

Cyclophosphamide
    Administration route: Oral
    Start date: 2012-04-28
    End date: 2012-04-30

Fludara
    Administration route: Oral
    Start date: 2012-04-28
    End date: 2012-04-30

Fludara
    Administration route: Oral
    Start date: 2012-06-02
    End date: 2012-06-04

Mabthera
    Start date: 2012-06-01
    End date: 2012-06-01

Mabthera
    Start date: 2012-04-27
    End date: 2012-04-27

Other drugs received by patient: Phosphoneuros; MAG 2; Dedrogyl; Valacyclovir Hydrochloride; Escitalopram; Bactrim; Difrarel



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