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Cyclophosphamide (Cyclophosphamide) - Febrile Neutropenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Febrile Neutropenia (521)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cyclophosphamide where reactions include febrile neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 521   Next >>

Possible Cyclophosphamide side effects in 65 year old female

Reported by a physician from Japan on 2012-08-24

Patient: 65 year old female, weighing 50.2 kg (110.6 pounds)

Reactions: Weight Decreased, Blood Bilirubin Increased, Cytomegalovirus Viraemia, Headache, Pyrexia, Interstitial Lung Disease, Oedema, Thrombocytopenia, Blood Sodium Decreased, Decreased Appetite, Vomiting, Stomatitis, Pneumonia, Alanine Aminotransferase Increased, Lymphopenia, Anaemia, Febrile Neutropenia, Rash, Blood Phosphorus Decreased, Blood Potassium Decreased, Diarrhoea, Alopecia, Aspartate Aminotransferase Increased, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Dosage: 30 mg/m2 x 1/4 week
    Start date: 2011-03-16

Adriamycin PFS
    Dosage: 40 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Carboplatin
    Dosage: 250 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 350 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Etoposide
    Dosage: 100 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Prednisolone
    Dosage: 1mg/kg x 1/2 week
    Start date: 2011-12-13
    End date: 2011-12-14

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Start date: 2011-03-16

Prednisolone
    Dosage: 2 mg/m2, 1x/day
    Administration route: Oral
    Start date: 2011-03-24

Ranimustine
    Dosage: 60 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-16

Vincristine Sulfate
    Dosage: 1 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Vindesine Sulfate
    Dosage: 2.4 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Other drugs received by patient: Mucosolvan; Lansoprazole; Sulfamethoxazole and Trimethoprim; Armodafinil; Zolpidem; Olopatadine HCL; Cefazolin Sodium; Ciprofloxacin HCL; Armodafinil; Zovirax; Magmitt; Alendronate Sodium



Possible Cyclophosphamide side effects in male

Reported by a physician from Germany on 2012-08-24

Patient: male

Reactions: Febrile Neutropenia, Skin Infection, Neutropenia, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1500 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Doxorubicin Hydrochloride
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Neulasta
    Dosage: 6 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-06
    End date: 2012-04-20

Prednisolone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-21

Rituximab
    Dosage: 750 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-01
    End date: 2012-04-16

Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Other drugs received by patient: MST / 00036302 /; Novalgin / 00169801 /; Rulid; Pantoprazole; Paspertin / 00041902 /; Acyclovir; Electrolytes NOS W / Macrogol 3350; Dipyrone INJ; Metoclopramide; Acyclovir



Possible Cyclophosphamide side effects in

Reported by a physician from United States on 2012-08-23

Patient:

Reactions: Confusional State, White Blood Cell Count Decreased, Sepsis, Febrile Neutropenia, Encephalopathy, Platelet Count Decreased, Cystitis, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Blinded Vorinostat
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Cyclophosphamide
    Dosage: 750 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Placebo
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Prednisone TAB
    Dosage: 100 mg, qd, on days 3-7
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25
    End date: 2012-07-29

Rituximab
    Dosage: 375 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Simvastatin
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Simvastatin
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Vincristine Sulfate
    Dosage: 1.4 mg, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25



Possible Cyclophosphamide side effects in female

Reported by a physician from United States on 2012-08-23

Patient: female

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-07-21

Cytarabine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-07-17
    End date: 2012-07-20

Dasatinib
    Dosage: 40 milligram daily;
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-29

Mercaptopurine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-07-13
    End date: 2012-07-21

Other drugs received by patient: Zofran; Miralax



Possible Cyclophosphamide side effects in

Reported by a physician from Japan on 2012-08-23

Patient:

Reactions: White Blood Cell Count Decreased, Stomatitis, Anaemia, Febrile Neutropenia, Constipation, Neutrophil Count Decreased

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 700 mg, qd
    Start date: 2010-10-26
    End date: 2010-10-26

Cyclophosphamide
    Dosage: 700 mg, qd
    Start date: 2010-12-07
    End date: 2010-12-07

Cyclophosphamide
    Dosage: 700 mg, qd
    Start date: 2010-11-16
    End date: 2010-11-16

Cyclophosphamide
    Dosage: 700 mg, once
    Indication: Breast Cancer
    Start date: 2010-09-29
    End date: 2010-10-29

Emend
    Dosage: 80 mg, qd
    Administration route: Oral
    Start date: 2010-10-27
    End date: 2010-10-28

Emend
    Dosage: 125 mg, qd
    Administration route: Oral
    Start date: 2010-12-07
    End date: 2010-12-07

Emend
    Dosage: 125 mg, once
    Administration route: Oral
    Indication: Prophylaxis of Nausea and Vomiting
    Start date: 2010-09-29
    End date: 2010-09-29

Emend
    Dosage: 125 mg, qd
    Administration route: Oral
    Start date: 2010-10-26
    End date: 2010-10-26

Emend
    Dosage: 80 mg, qd
    Administration route: Oral
    Start date: 2010-09-30
    End date: 2010-10-01

Emend
    Dosage: 80 mg, qd
    Administration route: Oral
    Start date: 2010-12-08
    End date: 2010-12-09

Emend
    Dosage: 80 mg, qd
    Administration route: Oral
    Start date: 2010-11-17
    End date: 2010-11-18

Emend
    Dosage: 125 mg, qd
    Administration route: Oral
    Start date: 2010-11-16
    End date: 2010-11-16

Epirubicin Hydrochloride
    Dosage: |100 mg, once
    Indication: Breast Cancer
    Start date: 2010-09-29
    End date: 2010-09-29

Epirubicin Hydrochloride
    Dosage: 100 mg, qd
    Start date: 2010-12-07
    End date: 2010-12-07

Epirubicin Hydrochloride
    Dosage: 100 mg, qd
    Start date: 2010-10-26
    End date: 2010-10-26

Epirubicin Hydrochloride
    Dosage: 100 mg, qd
    Start date: 2010-11-16
    End date: 2010-11-16

Other drugs received by patient: Granisetron Hydrochloride; Dexamethasone Sodium Phosphate; Mucosta; Decadron Phosphate; Dexamethasone Sodium Phosphate; Mucosta; Decadron Phosphate; Granisetron Hydrochloride; Mucosta; Mucosta; Granisetron Hydrochloride; Decadron Phosphate; Dexamethasone Sodium Phosphate; Granisetron Hydrochloride; Decadron Phosphate; Dexamethasone Sodium Phosphate



Possible Cyclophosphamide side effects in

Reported by a physician from United States on 2012-08-23

Patient:

Reactions: Confusional State, White Blood Cell Count Decreased, Sepsis, Febrile Neutropenia, Encephalopathy, Platelet Count Decreased, Cystitis, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Blinded Vorinostat
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Cyclophosphamide
    Dosage: 750 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Placebo
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Prednisone TAB
    Dosage: 100 mg, qd, on days 3-7
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25
    End date: 2012-07-29

Rituximab
    Dosage: 375 mg/m2, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25

Simvastatin
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Simvastatin
    Dosage: 400 mg, qd, on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-23
    End date: 2012-07-27

Vincristine Sulfate
    Dosage: 1.4 mg, once, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-25



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-22

Patient: male

Reactions: Pneumonia Bacterial, Febrile Neutropenia

Drug(s) suspected as cause:
Cisplatin
    Dosage: unk
    Indication: Thymoma Malignant
    Start date: 2011-08-01

Cyclophosphamide
    Dosage: unk
    Indication: Thymoma Malignant
    Start date: 2011-08-01

Doxorubicin HCL
    Dosage: unk
    Indication: Thymoma Malignant
    Start date: 2011-08-01

Vincristine
    Dosage: unk
    Indication: Thymoma Malignant
    Start date: 2011-08-01



Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-22

Patient: male

Reactions: Rectal Haemorrhage, Constipation, Cardiac Disorder, Hospitalisation, Granulocytopenia, Inappropriate Antidiuretic Hormone Secretion, Thrombocytopenia, Cardiac Failure Congestive, Pneumonia, Anaemia, Pancytopenia, Atrial Fibrillation, Febrile Neutropenia, Syncope, Embolism, Sepsis, Dehydration, Asthenia, Mantle Cell Lymphoma Recurrent, Leukopenia, Deep Vein Thrombosis, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Cyclophosphamide
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Mantle Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Mantle Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Mantle Cell Lymphoma



Possible Cyclophosphamide side effects in 54 year old female

Reported by a physician from United States on 2012-08-21

Patient: 54 year old female, weighing 68.0 kg (149.6 pounds)

Reactions: White Blood Cell Count Decreased, Anaemia, Febrile Neutropenia, Pancytopenia, Platelet Count Decreased, Device Related Infection, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Dosage: 10 mg/kg, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Carboplatin
    Dosage: 6 df, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Cyclophosphamide
    Dosage: 600 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Doxorubicin HCL
    Dosage: 60 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Paclitaxel
    Dosage: 80 mg/m2, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Pegfilgrastim
    Dosage: 480 mug, unk
    Indication: Chemotherapy
    Start date: 2011-12-22

Other drugs received by patient: Tylenol (Caplet); Emend; Levaquin; Decadron; Zofran / 00955302 /; Aloxi; Compazine



Possible Cyclophosphamide side effects in 41 year old male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-21

Patient: 41 year old male

Reactions: Ecthyma, Pseudomonas Infection, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: B-Cell Lymphoma

Doxorubicin HCL
    Indication: B-Cell Lymphoma

Prednisone TAB
    Dosage: unk
    Indication: B-Cell Lymphoma

Rituximab
    Indication: B-Cell Lymphoma

Vincristine
    Indication: B-Cell Lymphoma



Possible Cyclophosphamide side effects in male

Reported by a individual with unspecified qualification from United States on 2012-08-21

Patient: male, weighing 42.6 kg (93.8 pounds)

Reactions: Mouth Ulceration, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 2780 mg

Doxorubicin Hydrochloride
    Dosage: 152 mg

Etoposide
    Dosage: 750 mg

Prednisone
    Dosage: 646 mg

Rituximab (Muab C2b8 Anti Cd20)
    Dosage: 810 mg

Vincristine Sulfate
    Dosage: 3.6 mg



Possible Cyclophosphamide side effects in 59 year old female

Reported by a physician from Japan on 2012-08-18

Patient: 59 year old female

Reactions: Febrile Neutropenia

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Breast Cancer

Dexamethasone
    Dosage: 8 mg

Dexamethasone
    Dosage: 8 mg
    Administration route: Oral
    Indication: Supportive Care

Docetaxel
    Indication: Breast Cancer



Possible Cyclophosphamide side effects in male

Reported by a physician from India on 2012-08-17

Patient: male, weighing 65.0 kg (143.0 pounds)

Reactions: Diarrhoea, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Blinded Gp2013
    Dosage: code not broken
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-08-06

Blinded Mabthera
    Dosage: code not broken
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-08-06

Blinded NO Treatment Received
    Dosage: code not broken
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-08-06

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma

Prednisone TAB
    Administration route: Oral
    Indication: non-Hodgkin's Lymphoma

Vincristine
    Indication: non-Hodgkin's Lymphoma



Possible Cyclophosphamide side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-17

Patient: 36 year old female

Reactions: Febrile Neutropenia

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Breast Cancer

Dexamethasone
    Dosage: 8 mg

Dexamethasone
    Dosage: 8 mg
    Administration route: Oral
    Indication: Supportive Care

Docetaxel
    Indication: Breast Cancer



Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-16

Patient: male, weighing 73.5 kg (161.7 pounds)

Reactions: Escherichia Urinary Tract Infection, Febrile Neutropenia, Proteus Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1370 mg

Doxorubicin Hydrochloride
    Dosage: 91 mg

Prednisone
    Dosage: 350 mg

Rituximab (Maab C2b8 Anti Cd20, Chimeric)
    Dosage: 700 mg

Vincristine Sulfate
    Dosage: 2 mg



Possible Cyclophosphamide side effects in female

Reported by a physician from United States on 2012-08-16

Patient: female

Reactions: Abdominal Pain, Vomiting, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Febrile Neutropenia, Peripheral Sensory Neuropathy, Constipation, Fatigue, Diarrhoea, Neutropenia

Drug(s) suspected as cause:
Adriamycin PFS
    Dosage: cycle 3

Adriamycin PFS
    Dosage: cycle 4

Adriamycin PFS
    Dosage: cycle 2

Adriamycin PFS
    Dosage: cycle 1
    Indication: Breast Cancer

Cyclophosphamide
    Dosage: cycle 4

Cyclophosphamide
    Dosage: cycle 3
    Indication: Breast Cancer

Cyclophosphamide
    Dosage: cycle 1

Cyclophosphamide
    Dosage: cycle 2

Docetaxel
    Dosage: cycle 4

Docetaxel
    Dosage: cycle 3
    Indication: Breast Cancer

Docetaxel
    Dosage: cycle 2

Docetaxel
    Dosage: cycle 1

Doxorubicin Hydrochloride
    Dosage: cycle 3

Doxorubicin Hydrochloride
    Dosage: cycle 4
    Indication: Breast Cancer

Doxorubicin Hydrochloride
    Dosage: cycle 1

Doxorubicin Hydrochloride
    Dosage: cycle 2

NOV-002

NOV-002
    Dosage: administered approximately 3 hr apart
    Indication: Breast Cancer

NOV-002



Possible Cyclophosphamide side effects in female

Reported by a individual with unspecified qualification from United States on 2012-08-10

Patient: female, weighing 68.5 kg (150.7 pounds)

Reactions: White Blood Cell Count Decreased, Febrile Neutropenia, Feeling Cold

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1040 mg
    Start date: 2012-07-26

Doxorubicin Hydrochloride
    Dosage: 105 mg
    Start date: 2012-07-26

Pegfilgrastim
    Dosage: 6 mg
    Start date: 2012-07-27



Possible Cyclophosphamide side effects in

Reported by a physician from United States on 2012-08-10

Patient:

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 750 mg/m2, over 30-60 minutes on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-18
    End date: 2012-07-18

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-18
    End date: 2012-07-18

Prednisone TAB
    Dosage: 100 mg, qd on days 3-7
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-18
    End date: 2012-07-22

Rituximab
    Dosage: 375 mg/m2, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-18
    End date: 2012-07-18

Vincristine Sulfate
    Dosage: 1.4 mg/m2, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-18
    End date: 2012-07-18

Vorinostat
    Dosage: 400 mg, qd on days 1-5
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-07-16
    End date: 2012-07-20



Possible Cyclophosphamide side effects in 57 year old female

Reported by a physician from Japan on 2012-08-09

Patient: 57 year old female, weighing 55.6 kg (122.3 pounds)

Reactions: White Blood Cell Count Decreased, Disseminated Intravascular Coagulation, Febrile Neutropenia, Cardiac Arrest, Septic Shock

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 725 mg, 1x/day
    Indication: Breast Cancer
    Start date: 2012-06-25

Epirubicin Hydrochloride
    Dosage: 108.75 mg, 1x/day
    Indication: Breast Cancer
    Start date: 2012-06-25

Fluorouracil
    Dosage: 725 mg, 1x/day
    Indication: Breast Cancer
    Start date: 2012-06-25

Other drugs received by patient: Gabapentin; Ketalar; Sitagliptin Phosphate; Risperdal; Fentanyl Citrate; Celebrex; Bisoprolol Fumarate; Amaryl; Morphine



Possible Cyclophosphamide side effects in female

Reported by a physician from Netherlands on 2012-08-09

Patient: female, weighing 61.5 kg (135.3 pounds)

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 885 mg, unk
    Indication: Breast Cancer
    Start date: 2011-03-22

Epirubicin Hydrochloride
    Dosage: 177 mg, unk
    Indication: Breast Cancer
    Start date: 2011-03-22

Fluorouracil
    Dosage: 885 mg, unk
    Indication: Breast Cancer
    Start date: 2011-03-22

NO Treatment Received
    Dosage: no treatment received
    Indication: Breast Cancer

Other drugs received by patient: Granisetron



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-09

Patient:

Reactions: Dermatitis Allergic, Pneumonia, Angina Pectoris, Febrile Neutropenia, Cognitive Disorder, Hepatitis, Arrhythmia, Interstitial Lung Disease, Gastrointestinal Disorder, Progressive Multifocal Leukoencephalopathy, Cardiac Failure Congestive, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Indication: Diffuse Large B-Cell Lymphoma

Radiotherapy
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Cyclophosphamide side effects in

Reported by a individual with unspecified qualification from United States on 2012-08-07

Patient:

Reactions: Lung Infection, Febrile Neutropenia, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: over 30-60 minutes on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-08

Cyclophosphamide
    Dosage: over 30-60 minutes on day 3
    Start date: 2012-07-12
    End date: 2012-07-12

Cyclophosphamide
    Dosage: over 30-60 minutes on day 3
    Start date: 2012-03-01
    End date: 2012-03-01

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, on day 3
    Start date: 2012-07-12
    End date: 2012-07-12

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, on day 3
    Start date: 2012-03-01
    End date: 2012-03-01

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-08

Prednisone
    Dosage: 100 mg, qd on days 3-7
    Administration route: Oral
    Start date: 2012-03-01
    End date: 2012-03-05

Prednisone
    Dosage: 100 mg, qd on days 3-7
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-12

Prednisone
    Dosage: 100 mg, qd on days 3-7
    Administration route: Oral
    Start date: 2012-07-12
    End date: 2012-07-12

Rituximab
    Dosage: 375 mg/m2, on day 3
    Start date: 2012-03-01
    End date: 2012-03-01

Rituximab
    Dosage: 375 mg/m2, on day 3
    Start date: 2012-07-12
    End date: 2012-07-12

Rituximab
    Dosage: 375 mg/m2, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-08

Vincristine Sulfate
    Dosage: 1.4 mg/m2, on day 3
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-08
    End date: 2012-02-08

Vincristine Sulfate
    Dosage: 1.4 mg/m2, on day 3
    Start date: 2012-07-12
    End date: 2012-07-12

Vincristine Sulfate
    Dosage: 1.4 mg/m2, on day 3
    Start date: 2012-03-01
    End date: 2012-03-01

Vorinostat
    Dosage: on day 1-9
    Administration route: Oral
    Start date: 2012-02-28
    End date: 2012-03-07

Vorinostat
    Dosage: on day 1-9
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-06
    End date: 2012-02-14

Vorinostat
    Dosage: on day 1-5
    Administration route: Oral
    Start date: 2012-07-10
    End date: 2012-07-14



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-07

Patient:

Reactions: Hospitalisation, Neuropathy Peripheral, Vomiting, Febrile Neutropenia, Neutropenia, Neutrophil Count Decreased, Lymphoma

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Dosage: for 5 days
    Indication: B-Cell Lymphoma

Prednisone
    Dosage: for 5 days
    Indication: Diffuse Large B-Cell Lymphoma

Radiotherapy
    Indication: Diffuse Large B-Cell Lymphoma

Radiotherapy
    Indication: B-Cell Lymphoma

Rituximab
    Indication: B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Neupogen



Possible Cyclophosphamide side effects in 41 year old male

Reported by a physician from Canada on 2012-08-03

Patient: 41 year old male

Reactions: Ecthyma, Diarrhoea, Pseudomonas Infection, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: B-Cell Lymphoma Stage IV

Doxorubicin HCL
    Indication: B-Cell Lymphoma Stage IV

Prednisone
    Indication: B-Cell Lymphoma Stage IV

Rituximab
    Indication: B-Cell Lymphoma Stage IV

Vincristine
    Indication: B-Cell Lymphoma Stage IV

Other drugs received by patient: Epogen; Enoxaparin Sodium; Filgrastim



Possible Cyclophosphamide side effects in 57 year old female

Reported by a pharmacist from Japan on 2012-08-03

Patient: 57 year old female, weighing 55.6 kg (122.3 pounds)

Reactions: White Blood Cell Count Decreased, Disseminated Intravascular Coagulation, Febrile Neutropenia, Septic Shock, Cardiac Arrest

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 725 mg, 1x/day
    Indication: Breast Cancer
    Start date: 2012-06-25

Epirubicin Hydrochloride
    Dosage: 108.75 mg, 1x/day
    Indication: Breast Cancer
    Start date: 2012-06-25

Fluorouracil
    Dosage: 725 mg, 1x/day
    Indication: Breast Cancer
    Start date: 2012-06-25

Other drugs received by patient: Risperdal; Bisoprolol Fumarate; Fentanyl Citrate; Morphine; Ketalar; Amaryl; Gabapentin; Celebrex; Sitagliptin Phosphate



Possible Cyclophosphamide side effects in female

Reported by a physician from Japan on 2012-08-02

Patient: female

Reactions: Febrile Neutropenia, Septic Shock

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Breast Cancer
    Start date: 2012-06-25

Cyclophosphamide
    Start date: 2012-07-17
    End date: 2012-07-22

Epirubicin Hydrochloride
    Indication: Breast Cancer
    Start date: 2012-06-25

Epirubicin Hydrochloride
    Start date: 2012-07-17
    End date: 2012-07-22

Fluorouracil
    Start date: 2012-07-17
    End date: 2012-07-22

Fluorouracil
    Indication: Breast Cancer
    Start date: 2012-06-25

Other drugs received by patient: Amaryl; Gabapentin; Sitagliptin Phosphate; Celebrex; Fentanyl Citrate



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from Russian Federation on 2012-07-31

Patient:

Reactions: Vomiting, Acute Leukaemia, Febrile Neutropenia, Treatment Failure, Neutropenia, Toxicity To Various Agents, Neoplasm, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Chemoradiation
    Indication: Hodgkin's Disease

Cyclophosphamide
    Indication: Hodgkin's Disease

Dacarbazine
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Prednisone
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Indication: Hodgkin's Disease

Vinblastine Sulfate
    Indication: Hodgkin's Disease

Vincristine
    Indication: Hodgkin's Disease



Possible Cyclophosphamide side effects in female

Reported by a physician from Netherlands on 2012-07-30

Patient: female, weighing 61.5 kg (135.3 pounds)

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 885 mg, unk
    Indication: Breast Cancer
    Start date: 2011-03-22

Epirubicin
    Dosage: 177 mg, unk
    Indication: Breast Cancer
    Start date: 2011-03-22

Fluorouracil
    Dosage: 885 mg, unk
    Indication: Breast Cancer
    Start date: 2011-03-22

NO Treatment Received
    Dosage: no treatment received
    Indication: Breast Cancer

Other drugs received by patient: Granisetron



Possible Cyclophosphamide side effects in

Reported by a physician from Italy on 2012-07-27

Patient:

Reactions: Anaemia, Skin Toxicity, Febrile Neutropenia, Mucosal Inflammation, Neurotoxicity, Respiratory Failure, Sepsis, Neutropenia, Cardiotoxicity, Septic Shock, Thrombocytopenia, Myocardial Infarction, Diffuse Large B-Cell Lymphoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Epirubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Mabthera
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone and Prednisone
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Cyclophosphamide side effects in female

Reported by a physician from Spain on 2012-07-27

Patient: female, weighing 43.5 kg (95.7 pounds)

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-11-21

Fludarabine Phosphate
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-11-21

Ofatumumab
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-11-21

Other drugs received by patient: Levofloxacin; Tazobactam; Piperacilina



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