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Cyclophosphamide (Cyclophosphamide) - Atrial Fibrillation - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Atrial Fibrillation ()

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cyclophosphamide where reactions include atrial fibrillation. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of    Next >>

Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-22

Patient: male

Reactions: Rectal Haemorrhage, Constipation, Cardiac Disorder, Hospitalisation, Granulocytopenia, Inappropriate Antidiuretic Hormone Secretion, Thrombocytopenia, Cardiac Failure Congestive, Pneumonia, Anaemia, Pancytopenia, Atrial Fibrillation, Febrile Neutropenia, Syncope, Embolism, Sepsis, Dehydration, Asthenia, Mantle Cell Lymphoma Recurrent, Leukopenia, Deep Vein Thrombosis, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Mantle Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Mantle Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Mantle Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Mantle Cell Lymphoma



Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male, weighing 115.7 kg (254.5 pounds)

Reactions: Gastrointestinal Haemorrhage, Cholecystitis Acute, T-Cell Lymphoma, Disseminated Intravascular Coagulation, Pancytopenia, Atrial Fibrillation, Multi-Organ Failure, Sepsis, Acute Respiratory Distress Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Prednisone TAB
    Indication: T-Cell Lymphoma
    Start date: 2006-01-01

Adriamycin PFS
    Indication: T-Cell Lymphoma
    Start date: 2006-09-10

Cyclophosphamide
    Indication: T-Cell Lymphoma
    Start date: 2006-01-01

Vincristine
    Indication: T-Cell Lymphoma
    Start date: 2006-09-10

Remicade
    Dosage: 3 dose induction followed by maint. q 8 weeks, 300 mg on 29-jun-2006, total 27 infusions
    Indication: Rheumatoid Arthritis
    Start date: 2001-10-01
    End date: 2006-06-29

Other drugs received by patient: Azulfadine; Lisinopril



Possible Cyclophosphamide side effects in male

Reported by a individual with unspecified qualification from United States on 2012-08-13

Patient: male, weighing 73.0 kg (160.6 pounds)

Reactions: Pneumonia, Dyspnoea, Hypotension, Malnutrition, Pseudomonas Infection, Atrial Fibrillation, Pulmonary Embolism, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rituximab (Moab C2b8 Anti Cd20, Chimeric)
    Dosage: 750mg

Cyclophosphamide
    Dosage: 1500 mg

Vincristine Sulfate
    Dosage: 1.5mg

Doxorubicin Hydrochloride
    Dosage: 75 mg



Possible Cyclophosphamide side effects in male

Reported by a physician from Italy on 2012-08-07

Patient: male

Reactions: Oesophageal Candidiasis, Oral Candidiasis, Blood Lactate Dehydrogenase Increased, Atrial Fibrillation, Cytomegalovirus Infection, Hyperaemia, Abdominal Pain Upper

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mabcampath
    Dosage: 20 mg, qd
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-01-09
    End date: 2012-01-11

Cyclophosphamide
    Dosage: 285 mg, qd
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-01-09
    End date: 2012-01-11

Fludarabine Phosphate
    Dosage: 38 mg, qd
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-01-09
    End date: 2012-01-11

Other drugs received by patient: Dexamethasone Sodium Phosphate; Omeprazole / Sodium Bicarbonate; Filgrastim; Levofloxacin; Decadron Phosphate; RED Blood Cells; Flecainide Acetate; RED Blood Cells; Dexamethasone; Acyclovir; Idroplurivit; Dexamethasone Sodium Phosphate; Folina



Possible Cyclophosphamide side effects in male

Reported by a physician from Italy on 2012-07-19

Patient: male

Reactions: Oesophageal Candidiasis, Cytomegalovirus Infection, Atrial Fibrillation, Abdominal Pain Upper

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 285 mg, qd
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-01-09
    End date: 2012-01-11

Mabcampath
    Dosage: 20 mg, qd
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-01-09
    End date: 2012-01-11

Fludarabine Phosphate
    Dosage: 38 mg, qd
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-01-09
    End date: 2012-01-11

Other drugs received by patient: RED Blood Cells; Omeprazole Sodium; RED Blood Cells; Idroplurivit; Decadron; Folina; Levofloxacin; Dexamethasone Sodium Phosphate; Flecainide Acetate; Acyclovir; Filgrastim



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-17

Patient: male

Reactions: Cardiac Murmur, Vomiting, Alanine Aminotransferase Increased, Hypotension, Atrial Fibrillation, Headache, Rash, Pyrexia, Diarrhoea, Oedema Peripheral, Vertigo, Neutropenia, Blood Creatinine Increased, Leukopenia, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Escitalopram
    Dosage: 10 mg, qd, 1 pill
    Indication: Product Used FOR Unknown Indication

Valacyclovir Hydrochloride
    Dosage: 500 mg, unk
    Indication: Product Used FOR Unknown Indication

Cyclophosphamide
    Dosage: 400 mg, qd, cycle 2
    Start date: 2012-06-02
    End date: 2012-06-04

Fludara
    Dosage: 80 mg, qd, cycle 2
    Start date: 2012-06-02
    End date: 2012-06-04

Bactrim
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Fludara
    Dosage: 80 mg, unk, cycle 1
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-04-28
    End date: 2012-04-30

Mabthera
    Dosage: 755 mg, once, cycle 1
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-04-27
    End date: 2012-04-27

Cyclophosphamide
    Dosage: 500 mg, qd, cycle 1
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-04-28
    End date: 2012-04-30

Dedrogyl
    Dosage: 15 mg/100ml (3 drps/d)
    Indication: Product Used FOR Unknown Indication

MAG 2
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Mabthera
    Dosage: 1000 mg, once, cycle 2
    Start date: 2012-06-01
    End date: 2012-06-01

Phosphoneuros
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Difrarel
    Dosage: 100 mg, unk
    Indication: Product Used FOR Unknown Indication



Possible Cyclophosphamide side effects in male

Reported by a consumer/non-health professional from Germany on 2012-07-10

Patient: male, weighing 60.0 kg (132.0 pounds)

Reactions: Candida Pneumonia, Bronchopneumonia, Tachycardia, Atrial Fibrillation, Febrile Neutropenia, General Physical Health Deterioration, Lactic Acidosis, Respiratory Distress, Respiratory Failure, Skin Lesion, Pseudomonal Sepsis, Tracheitis, Septic Shock

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 92 mg, unk
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2010-01-07
    End date: 2010-01-07

Pegfilgrastim
    Dosage: 6 mg, once
    Start date: 2010-03-01
    End date: 2010-03-01

Cyclophosphamide
    Dosage: 690 mg, once
    Start date: 2010-02-22
    End date: 2010-02-22

Campath
    Dosage: 30 mg, qd
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2010-01-07
    End date: 2010-01-08

Vincristine
    Dosage: 2 mg, qd
    Start date: 2010-02-22
    End date: 2010-02-22

Vasopressin
    Dosage: unk
    Indication: Blood Pressure Management

Vincristine
    Dosage: 2 mg, unk
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2010-01-07
    End date: 2010-01-07

Cyclophosphamide
    Dosage: 1380 mg, unk
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2010-01-07
    End date: 2010-01-07

Doxorubicin HCL
    Dosage: 46 mg, once
    Start date: 2010-02-22
    End date: 2010-02-22

Campath
    Dosage: 30 mg, qd
    Start date: 2010-02-22
    End date: 2010-02-23

Prednisone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2010-01-07
    End date: 2010-01-11

Prednisone
    Dosage: 100 mg, qdx5
    Administration route: Oral
    Start date: 2010-02-22
    End date: 2010-02-26

Pegfilgrastim
    Dosage: 3 mg, qd
    Indication: Peripheral T-Cell Lymphoma Unspecified

Other drugs received by patient: Zienam; Posaconazole; Taranic; Zienam; Taranic; Candiohermal; Candiohermal



Possible Cyclophosphamide side effects in 73 year old male

Reported by a physician from Germany on 2012-07-06

Patient: 73 year old male

Reactions: Stenotrophomonas Infection, Febrile Neutropenia, Atrial Fibrillation, Ileus Paralytic, Multi-Organ Failure, Pneumonia Bacterial, Respiratory Failure, Cardiac Failure, Oesophagitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1500 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2009-06-25
    End date: 2009-09-03

Vincristine
    Dosage: 1 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2009-06-17
    End date: 2009-09-03

Prednisone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: T-Cell Lymphoma
    Start date: 2009-06-17
    End date: 2009-09-10

Doxorubicin HCL
    Dosage: 100 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2009-06-25
    End date: 2009-09-03

Campath
    Dosage: 30 mg, q2w
    Indication: T-Cell Lymphoma
    Start date: 2009-06-25
    End date: 2009-09-04

Pegfilgrastim
    Dosage: 6 mg, q2w
    Indication: T-Cell Lymphoma
    Start date: 2009-06-29
    End date: 2009-09-06

Pegfilgrastim
    Indication: Prophylaxis

Other drugs received by patient: Ciprofloxacin



Possible Cyclophosphamide side effects in male

Reported by a physician from Italy on 2012-06-27

Patient: male

Reactions: Oesophageal Candidiasis, Atrial Fibrillation, Cytomegalovirus Infection, Abdominal Pain Upper

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fludarabine Phosphate
    Dosage: 38 mg, qd
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-01-09
    End date: 2012-01-11

Cyclophosphamide
    Dosage: 285 mg, qd
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-01-09
    End date: 2012-01-11

Mabcampath
    Dosage: 20 mg, qd
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-01-09
    End date: 2012-01-11

Other drugs received by patient: RED Blood Cells; Filgrastim; Folina; Levofloxacin; Acyclovir; Decadron; Omeprazole Sodium; RED Blood Cells; Flecainide Acetate; Dexamethasone Sodium Phosphate; Idroplurivit



Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-18

Patient: male

Reactions: Bradypnoea, Hypotension, Atrial Fibrillation, Device Occlusion, Loss of Consciousness, Death, Ventricular Tachycardia, Coronary Artery Occlusion, Pneumothorax, Pleural Effusion, Haemolytic Anaemia, Cardiac Arrest

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Fludara
    Dosage: 40 mg, qd
    Indication: Waldenstrom's Macroglobulinaemia
    Start date: 2012-02-10
    End date: 2012-02-12

Cyclophosphamide
    Dosage: unk
    Start date: 2012-03-19

Cyclophosphamide
    Dosage: 450 mg, qd
    Indication: Waldenstrom's Macroglobulinaemia
    Start date: 2012-02-10
    End date: 2012-02-12

Mabthera
    Dosage: 650 mg, unk
    Indication: Waldenstrom's Macroglobulinaemia
    Start date: 2012-02-13
    End date: 2012-02-13

Mabthera
    Dosage: unk
    Start date: 2012-03-22

Other drugs received by patient: Vastarel; Acetaminophen; Mirtazapine; Pravastatin; Lorazepam; Zantac; Sotalol HCL; Potassium Chloride



Possible Cyclophosphamide side effects in

Reported by a physician from United Kingdom on 2012-05-16

Patient:

Reactions: Atrial Fibrillation, Neutropenia

Drug(s) suspected as cause:
Vincristine
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: cycle 1

Cyclophosphamide
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Prednisolone
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Rituximab
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Prednisolone
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: cycle 1

Cyclophosphamide
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Steroids NOS



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-03

Patient:

Reactions: Atrial Fibrillation, Neutropenia

Drug(s) suspected as cause:
Prednisolone Acetate
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Vincristine Sulfate
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Rituximab
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine Sulfate
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: cycle 1
    Indication: Diffuse Large B-Cell Lymphoma

Prednisolone Acetate
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Rituximab
    Dosage: cycle 1
    Indication: Burkitt's Lymphoma

Other drugs received by patient: Steroids NOS



Possible Cyclophosphamide side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-03

Patient: female

Reactions: Atrial Fibrillation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Pegfilgrastim
    Indication: Breast Cancer

Doxorubicin HCL
    Indication: Breast Cancer

Bevacizumab

Cyclophosphamide
    Indication: Breast Cancer

Paclitaxel
    Indication: Breast Cancer

Bevacizumab
    Indication: Breast Cancer



Possible Cyclophosphamide side effects in 75 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-22

Patient: 75 year old male

Reactions: Histiocytosis Haematophagic, Disseminated Intravascular Coagulation, Atrial Fibrillation, Interstitial Lung Disease, Cerebral Infarction, Aspergillosis, Pseudomembranous Colitis, Cytomegalovirus Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Etanercept
    Indication: Rheumatoid Arthritis

Sulfasalazine
    Indication: Rheumatoid Arthritis

Cyclophosphamide
    Dosage: pulse therapy
    Indication: Rheumatoid Arthritis

Methylprednisolone
    Dosage: dose decreased to 500mg,250mg,125mg,100mg,60mg
    Indication: Rheumatoid Arthritis



Possible Cyclophosphamide side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-04-12

Patient: 76 year old male, weighing 70.8 kg (155.8 pounds)

Reactions: Blood Bilirubin Increased, Blood Albumin Decreased, Prothrombin Time Prolonged, C-Reactive Protein Increased, Blood Sodium Increased, Circulatory Collapse, Blood Creatinine Increased, Melaena, Hypothermia, Platelet Count Decreased, Pancreatitis, Neutrophil Count Decreased, Pco2 Decreased, Blood Magnesium Decreased, PO2 Decreased, RED Blood Cell Count Decreased, Electrolyte Imbalance, Blood Glucose Increased, White Blood Cell Count Decreased, Blood Urea Increased, Atrial Flutter, Alanine Aminotransferase Increased, International Normalised Ratio Increased, Metamyelocyte Count Increased, Atrial Fibrillation, Iron Deficiency, Condition Aggravated, Protein Total Decreased, Haemoglobin Decreased, Myelocyte Count Increased, Torsade DE Pointes, Syncope, Blood Potassium Decreased, Sepsis, Altered State of Consciousness, Cardiac Arrest

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Revlimid
    Administration route: Oral
    End date: 2011-12-07

Dexamethasone 4MG TAB
    Administration route: Oral
    Start date: 2011-10-22

Revlimid
    Administration route: Oral
    Start date: 2011-10-22

Cyclophosphamide
    Administration route: Oral
    End date: 2011-11-26

Dexamethasone 4MG TAB
    Administration route: Oral
    End date: 2011-12-06

Cyclophosphamide
    Administration route: Oral
    Start date: 2011-10-22

Other drugs received by patient: Iron Infusion; Arachis Olli Enema; Difflam; Albuterol



Possible Cyclophosphamide side effects in 75 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-06

Patient: 75 year old male

Reactions: Histiocytosis Haematophagic, Drug Ineffective, Disseminated Intravascular Coagulation, Condition Aggravated, Atrial Fibrillation, Multi-Organ Failure, Interstitial Lung Disease, Cytomegalovirus Infection, Pseudomembranous Colitis, Aspergillosis, Haemorrhagic Cerebral Infarction

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Etanercept
    Indication: Interstitial Lung Disease

Methylprednisolone
    Indication: Interstitial Lung Disease

Cyclophosphamide
    Indication: Interstitial Lung Disease



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-23

Patient:

Reactions: Thrombosis, Confusional State, Tubulointerstitial Nephritis, Blood Stem Cell Harvest Failure, Disease Progression, Fatigue, Neuropathy Peripheral, Thrombocytopenia, Anaemia, Hyperglycaemia, Lymphopenia, Atrial Fibrillation, Muscular Weakness, Rash, Haematotoxicity, Renal Failure, Diarrhoea, Insomnia, Neutropenia, Leukopenia, Infection

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 40 mg, days 1, 8, 15, and 22 of each cycle., po
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-07-01

Cyclophosphamide
    Dosage: 300 mg/m2, days 1, 8, and 15, unk
    Indication: Multiple Myeloma

Revlimid
    Dosage: 25 mg, daily on days 1-21 of a 28-day cycle, po
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-07-01

Other drugs received by patient: Aspirin



Possible Cyclophosphamide side effects in 63 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-03-23

Patient: 63 year old male

Reactions: Agitation, Histiocytosis Haematophagic, Brain Herniation, Atrial Fibrillation, Encephalitis Fungal, Cerebral Ischaemia, Zygomycosis, Brain Oedema, Bone Marrow Failure, Acute Respiratory Failure, Subendocardial Ischaemia, Shock

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Solu-Medrol
    Dosage: 100 mg, 1x/day
    Start date: 2011-06-07

Cyclophosphamide
    Dosage: unk
    Start date: 2011-06-07
    End date: 2011-06-07

Solu-Medrol
    Dosage: 1 g, 1x/day
    Start date: 2011-06-03
    End date: 2011-06-06



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-03-21

Patient:

Reactions: Pancreatitis Acute, Bronchopulmonary Aspergillosis, Anaemia, Atrial Fibrillation, Pyrexia, Arrhythmia, Sinus Bradycardia, Epidermolysis, Ileus Paralytic, Astringent Therapy, Neuropathy Peripheral, Cardiac Failure, Sepsis, Neutropenia, Thrombocytopenia, Infusion Related Reaction

Adverse event resulted in: death

Drug(s) suspected as cause:
Mabthera
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Vincristine
    Dosage: days 4 and 11, at a maximum dose of 2 mg
    Indication: Mantle Cell Lymphoma

Methotrexate
    Dosage: for 24 hours continuous infusion day 1

Dexamethasone
    Dosage: days 1-4 and 11-14
    Indication: Mantle Cell Lymphoma

Cytarabine
    Dosage: days 2 to 3
    Indication: Mantle Cell Lymphoma

Doxorubicin Hydrochloride
    Dosage: days 4 to 5
    Indication: Mantle Cell Lymphoma

Cyclophosphamide
    Dosage: days 1 to 3
    Indication: Mantle Cell Lymphoma

Methotrexate
    Dosage: bolus infusion day 1
    Indication: Mantle Cell Lymphoma



Possible Cyclophosphamide side effects in 69 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 69 year old male

Reactions: Death, Blood Bilirubin Increased, Hepatotoxicity, Nausea, Atrial Flutter, Sepsis, Palmar-Plantar Erythrodysaesthesia Syndrome, Atrial Fibrillation, Myocardial Infarction

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Fluconazole
    Indication: Antifungal Prophylaxis

Cytarabine
    Indication: Chemotherapy

Acyclovir
    Indication: Antiviral Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Metronidazole
    Indication: Antibiotic Prophylaxis

Clofarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis

Rabbit Antithymocyte Globulin
    Indication: Bone Marrow Conditioning Regimen

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen



Possible Cyclophosphamide side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-14

Patient: 61 year old male

Reactions: Vomiting, Atrial Flutter, Nausea, Hepatotoxicity, Atrial Fibrillation, Oedema, Device Related Infection, Decreased Appetite

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Metronidazole
    Indication: Antibiotic Prophylaxis

Cytarabine
    Indication: Chemotherapy

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Levofloxacin
    Indication: Antibiotic Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Clofarabine
    Indication: Chemotherapy

Acyclovir
    Indication: Antiviral Prophylaxis



Possible Cyclophosphamide side effects in 69 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-10

Patient: 69 year old male

Reactions: Blood Bilirubin Increased, Nausea, Atrial Fibrillation, Palmar-Plantar Erythrodysaesthesia Syndrome, Aplasia, Transaminases Increased, Sepsis, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Acute Myeloid Leukaemia

Clofarabine
    Indication: Acute Myeloid Leukaemia

Mycophenolate Mofetil
    Indication: Acute Myeloid Leukaemia

Cytarabine
    Indication: Acute Myeloid Leukaemia

Cyclosporine
    Indication: Acute Myeloid Leukaemia

Anti-Thymocyte Globulin NOS
    Indication: Acute Myeloid Leukaemia



Possible Cyclophosphamide side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-10

Patient: 61 year old male

Reactions: Vomiting, Nausea, Oedema, Atrial Fibrillation, Device Related Infection, Aplasia, Transaminases Increased, Decreased Appetite

Drug(s) suspected as cause:
Mycophenolate Mofetil
    Indication: Acute Myeloid Leukaemia

Cyclosporine
    Indication: Acute Myeloid Leukaemia

Anti-Thymocyte Globulin NOS
    Indication: Acute Myeloid Leukaemia

Clofarabine
    Indication: Acute Myeloid Leukaemia

Cyclophosphamide
    Indication: Acute Myeloid Leukaemia

Cytarabine
    Indication: Acute Myeloid Leukaemia



Possible Cyclophosphamide side effects in 73 year old female

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-02-28

Patient: 73 year old female

Reactions: Nausea, Atrial Fibrillation, Asthenia, Leukopenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Breast Cancer
    Start date: 2011-03-30
    End date: 2011-03-30

Taxotere
    Indication: Breast Cancer
    Start date: 2011-03-30
    End date: 2011-03-30



Possible Cyclophosphamide side effects in female

Reported by a physician from Norway on 2012-02-23

Patient: female, weighing 103.0 kg (226.6 pounds)

Reactions: Left Ventricular Dysfunction, Atrial Fibrillation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: last dose prior to sae 19/dec/2011
    Indication: Breast Cancer
    Start date: 2011-08-02
    End date: 2012-01-03

Epirubicin Hydrochloride
    Dosage: last dose prior to sae 3/oct/2011
    Indication: Breast Cancer
    Start date: 2011-08-02

Paclitaxel
    Dosage: last dose prior to sae 19/dec/2011
    Indication: Breast Cancer
    Start date: 2011-10-24
    End date: 2012-01-03

Cyclophosphamide
    Dosage: last dose prior to sae 3/oct/2011
    Indication: Breast Cancer
    Start date: 2011-08-02

Fluorouracil
    Dosage: last dose prior to sae 3/oct/2011
    Indication: Breast Cancer
    Start date: 2011-08-02

Other drugs received by patient: Lovaza; Magnesium; Vitamin K TAB; Ascorbic Acid; Vitamin E; Vitamin D; Glucosamine; Nexium; Levothyroxine Sodium; Zinc Sulfate; Triobe; Liothyronin; Calcium



Possible Cyclophosphamide side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-02-14

Patient: 76 year old male, weighing 70.8 kg (155.8 pounds)

Reactions: Hypothermia, Condition Aggravated, Atrial Fibrillation, Syncope, Sepsis, Circulatory Collapse, Pancreatitis, Electrolyte Imbalance, Altered State of Consciousness, Cardiac Arrest

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Administration route: Oral
    Start date: 2011-10-22

Revlimid
    Administration route: Oral
    Start date: 2011-10-22

Dexamethasone
    Administration route: Oral
    Start date: 2011-10-22

Dexamethasone
    Administration route: Oral
    End date: 2011-12-06

Revlimid
    Administration route: Oral
    End date: 2011-12-07

Cyclophosphamide
    Administration route: Oral
    End date: 2011-11-26

Other drugs received by patient: Arachis Olli Enema; Difflam; Albuterol Sulfate Autohaler



Possible Cyclophosphamide side effects in

Reported by a physician from Italy on 2012-02-10

Patient:

Reactions: Pancreatitis Acute, Bronchopulmonary Aspergillosis, Anaemia, Atrial Fibrillation, Ileus Paralytic, Epidermolysis, Sinus Bradycardia, Astringent Therapy, Neuropathy Peripheral, Cardiac Failure, Embolism, Sepsis, Neutropenia, Thrombocytopenia, Infusion Related Reaction, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Mantle Cell Lymphoma

Mabthera
    Indication: Mantle Cell Lymphoma

Cytarabine
    Indication: Mantle Cell Lymphoma

Vincristine
    Dosage: at a maximum dose of 2 mg
    Indication: Mantle Cell Lymphoma

Methotrexate
    Indication: Mantle Cell Lymphoma

Dexamethasone
    Indication: Mantle Cell Lymphoma

Doxorubicin HCL
    Indication: Mantle Cell Lymphoma



Possible Cyclophosphamide side effects in male

Reported by a physician from Italy on 2012-01-26

Patient: male

Reactions: Atrial Fibrillation, Neutropenia, Thrombocytopenia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: 1 milligram;
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-14
    End date: 2011-11-14

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-14
    End date: 2011-11-14

Doxorubicin HCL
    Dosage: 50 milligram;
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-14
    End date: 2011-11-14

Other drugs received by patient: Prednisone TAB; Lasix; Methylprednisolone; Norvasc; Clexane T; Omeprazole



Possible Cyclophosphamide side effects in

Reported by a individual with unspecified qualification from United States on 2012-01-25

Patient:

Reactions: Thrombosis, Gastrointestinal Haemorrhage, Rectal Haemorrhage, Constipation, Cardiac Disorder, Inappropriate Antidiuretic Hormone Secretion, Pleural Effusion, Thrombocytopenia, Cardiac Failure Congestive, Pneumonia, Anaemia, Atrial Fibrillation, Pancytopenia, Febrile Neutropenia, Syncope, Embolism, Sepsis, Dehydration, Neutropenia, Leukopenia, Deep Vein Thrombosis, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisone
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Mabthera
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: maximum 2.0 mg
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Sargramostim



Possible Cyclophosphamide side effects in

Reported by a individual with unspecified qualification from United States on 2012-01-25

Patient:

Reactions: Parainfluenzae Virus Infection, Bacteraemia, Dehydration, Febrile Neutropenia, Atrial Fibrillation, Arthritis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Lymphoma

Mabthera
    Indication: Lymphoma

Other drugs received by patient: Pegfilgrastim



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