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Clozaril (Clozapine) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (234)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clozaril (Clozapine) life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 234   Next >>

Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-27

Patient: male, weighing 81.7 kg (179.7 pounds)

Reactions: Confusional State, Blood Creatine Phosphokinase Increased, Anaemia, General Physical Health Deterioration, Pyrexia, Disorientation, Fall, C-Reactive Protein Increased, Sepsis, Gait Disturbance, Neuroleptic Malignant Syndrome, Neutropenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Simvastatin; Escitalopram; Tamsulosin Hydrochloride; Dekristol; Omeprazole; Hyoscine Hydrobromide; Ferrous Sulfate TAB



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-08-24

Patient: male

Reactions: White Blood Cell Count Decreased, Neutrophil Count Increased, Burkitt's Lymphoma, Platelet Count Decreased, non-Hodgkin's Lymphoma, Neutropenia, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Amitriptyline Hydrochloride



Possible Clozaril side effects in male

Reported by a physician from Japan on 2012-08-24

Patient: male, weighing 52.0 kg (114.4 pounds)

Reactions: Grand MAL Convulsion, Tachycardia, Enteritis Infectious, Loss of Consciousness, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 175mg, daily
    Administration route: Oral
    Start date: 2012-02-10
    End date: 2012-02-12

Clozaril
    Dosage: 200 mg, daily
    Administration route: Oral
    Start date: 2012-02-13
    End date: 2012-02-16

Clozaril
    Dosage: 50 mg, daily
    Administration route: Oral
    Start date: 2012-01-23
    End date: 2012-01-26

Clozaril
    Dosage: 75 mg, daily
    Administration route: Oral
    Start date: 2012-01-27
    End date: 2012-01-29

Clozaril
    Dosage: 150 mg, daily
    Administration route: Oral
    Start date: 2012-02-06
    End date: 2012-02-09

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Start date: 2012-03-02
    End date: 2012-03-29

Clozaril
    Dosage: 375 mg, daily
    Administration route: Oral
    Start date: 2012-04-06
    End date: 2012-04-12

Clozaril
    Dosage: 500 mg, daily
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    Start date: 2012-01-19

Clozaril
    Dosage: 25 mg, daily
    Administration route: Oral
    Start date: 2012-01-20
    End date: 2012-01-22

Clozaril
    Dosage: 275 mg, daily
    Administration route: Oral
    Start date: 2012-02-24
    End date: 2012-03-01

Clozaril
    Dosage: 300mg, daily
    Administration route: Oral
    Start date: 2012-03-30
    End date: 2012-04-05

Clozaril
    Dosage: 450 mg, daily
    Administration route: Oral
    Start date: 2012-04-13

Clozaril
    Dosage: 12.5 mg, daily
    Administration route: Oral
    Start date: 2012-01-19
    End date: 2012-01-19

Clozaril
    Dosage: 100 mg, daily
    Administration route: Oral
    Start date: 2012-01-30
    End date: 2012-02-02

Clozaril
    Dosage: 600 mg daily
    Administration route: Oral
    Start date: 2012-04-27
    End date: 2012-04-28

Clozaril
    Dosage: 125 mg, daily
    Administration route: Oral
    Start date: 2012-02-03
    End date: 2012-02-05

Clozaril
    Dosage: 225 mg, daily
    Administration route: Oral
    Start date: 2012-02-17
    End date: 2012-02-23

Clozaril
    Dosage: 400 mg daily
    Administration route: Oral
    Start date: 2012-04-29

Other drugs received by patient: Lithium Carbonate; Lithium Carbonate; Artane



Possible Clozaril side effects in male

Reported by a physician from Japan on 2012-08-24

Patient: male

Reactions: Dysphagia, Pneumonia Aspiration, Blood Pressure Systolic Increased, Hallucination, Auditory, Pyrexia, Sedation, Sputum Increased, Depressed Level of Consciousness, Sputum Retention

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 100 mg, qd
    Administration route: Oral
    Start date: 2010-08-20
    End date: 2010-08-21

Clozaril
    Dosage: 50 mg, qd
    Administration route: Oral
    Start date: 2010-09-21
    End date: 2010-09-23

Clozaril
    Dosage: 25 mg, qd
    Administration route: Oral
    Start date: 2010-09-24
    End date: 2010-09-28

Clozaril
    Dosage: 50 mg, qd
    Administration route: Oral
    Start date: 2010-08-15
    End date: 2010-08-17

Clozaril
    Dosage: 75 mg, qd
    Administration route: Oral
    Start date: 2010-08-18
    End date: 2010-08-19

Clozaril
    Dosage: 175 mg, qd
    Administration route: Oral
    Start date: 2010-08-28
    End date: 2010-08-30

Clozaril
    Dosage: 200 mg, qd
    Administration route: Oral
    Start date: 2010-09-13
    End date: 2010-09-20

Clozaril
    Dosage: 12.5 mg, qd
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    Start date: 2010-08-11
    End date: 2010-08-11

Clozaril
    Dosage: 150 mg, qd
    Start date: 2010-08-25
    End date: 2010-08-27

Clozaril
    Dosage: 25 mg, qd
    Administration route: Oral
    Start date: 2010-08-12
    End date: 2010-08-14

Clozaril
    Dosage: 125 mg, qd
    Administration route: Oral
    Start date: 2010-08-22
    End date: 2010-08-24

Clozaril
    Dosage: 200 mg, qd
    Administration route: Oral
    Start date: 2010-08-31
    End date: 2010-09-06

Clozaril
    Dosage: 250 mg, qd
    Administration route: Oral
    Start date: 2010-09-07
    End date: 2010-09-12

Other drugs received by patient: Haloperidol; Risperidone; Potassium Chloride; Famotidine; Promethazine HCL; Olanzapine; Lactec; Magmitt Kenei; Haloperidol; Aripiprazole; Physiosol 3; Olanzapine; Quetiapine Fumarate; Physiosol 3; Sulbactam Sodium; Amoxicillin; Ceftriaxone Sodium; Flunitrazepam; Levomepromazine Maleate; Olanzapine; TPN Electrolytes IN Plastic Container; M.v.i.



Possible Clozaril side effects in 49 year old female

Reported by a physician from United Kingdom on 2012-08-23

Patient: 49 year old female

Reactions: Eosinophil Count Decreased, Scratch, White Blood Cell Count Decreased, Tooth Infection, Off Label Use, Road Traffic Accident, Platelet Count Decreased, Injury, Neutropenia, Toothache, Neutrophil Count Decreased, Infection Susceptibility Increased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-01-12
    End date: 2012-01-17

Clozaril
    Administration route: Oral

Clozaril
    Administration route: Oral
    Start date: 2006-08-14
    End date: 2012-01-09

Clozaril
    Administration route: Oral

Mirtazapine
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21

Topiramate
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Amoxicillin; Zopiclone; Quetiapine Fumarate



Possible Clozaril side effects in male

Reported by a physician from Australia on 2012-08-23

Patient: male, weighing 109.0 kg (239.8 pounds)

Reactions: Electrocardiogram QT Prolonged, Blood Creatine Phosphokinase Increased, Head Injury, Hallucination, Auditory, Pyrexia, Feeling Cold, Myalgia, Fatigue, Malaise, C-Reactive Protein Increased, Chest Pain, Injury, Tenderness, Myoglobin Blood Increased, Myocarditis, White Blood Cell Count Increased, Decreased Appetite, Chest Discomfort, Dyspnoea, Nausea, Tachyarrhythmia, Troponin T Increased, Aggression, Tremor, Affective Disorder, Mental Impairment, Heart Rate Increased, Electrocardiogram Abnormal, Suicide Attempt, Troponin I Increased, Sinus Tachycardia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 325 mg
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    Start date: 2004-08-10

Clozaril
    Dosage: 375 mg, unk
    Administration route: Oral
    Start date: 2012-03-01
    End date: 2012-03-12

Clozaril
    Dosage: 350 mg, qd
    Administration route: Oral
    Start date: 2004-08-11
    End date: 2007-07-01

Clozaril
    Dosage: 275 mg, unk
    Administration route: Oral
    Start date: 2012-02-12

Clozaril
    Dosage: 300 mg, unk
    Administration route: Oral

Other drugs received by patient: Omeprazole; Venlafaxine HCL; Quetiapine; Olanzapine; Seroquel; Diazepam; Nitrazepam; Clozapine; Multi-Vitamin; Effexor; Seroquel; Nitrazepam



Possible Clozaril side effects in 49 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-22

Patient: 49 year old female

Reactions: Scratch, White Blood Cell Count Decreased, Eosinophil Count Decreased, Tooth Infection, Off Label Use, Road Traffic Accident, Platelet Count Decreased, Toothache, Neutropenia, Injury

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 75 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-01-12
    End date: 2012-01-17

Mirtazapine
    Dosage: 45 mg, qd
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Quetiapine Fumarate; Zopiclone; Antibiotics; Amoxicillin



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-22

Patient: female

Reactions: Pneumonia, Parkinson's Disease

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Levaquin



Possible Clozaril side effects in male

Reported by a physician from Canada on 2012-08-21

Patient: male

Reactions: White Blood Cell Count Decreased, Agranulocytosis, Anaemia, Bone Marrow Failure, Febrile Neutropenia, Pyrexia, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Sertraline Hydrochloride; Kemadrin; Calcium with Vitamin D; Docusate; Zyprexa; Uromax



Possible Clozaril side effects in female

Reported by a physician from United Kingdom on 2012-08-20

Patient: female

Reactions: Scratch, Eosinophil Count Decreased, White Blood Cell Count Decreased, Tooth Infection, Road Traffic Accident, Neutropenia, Injury, Toothache, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 650 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-08-14
    End date: 2012-01-09

Clozaril
    Dosage: 75 mg, unk
    Administration route: Oral
    Start date: 2012-01-12
    End date: 2012-01-17

Mirtazapine
    Dosage: 45 mg, unk
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-20

Patient: female

Reactions: White Blood Cell Count Decreased, Eosinophil Count Decreased, Scratch, Tooth Infection, Road Traffic Accident, Neutropenia, Injury, Toothache, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 650 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-08-14
    End date: 2012-01-09

Clozaril
    Dosage: 75 mg, unk
    Administration route: Oral
    Start date: 2012-01-12
    End date: 2012-01-17

Mirtazapine
    Dosage: 45 mg, unk
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21



Possible Clozaril side effects in female

Reported by a physician from Australia on 2012-08-20

Patient: female

Reactions: Electrocardiogram QT Prolonged, Confusional State, Urinary Tract Infection, Hyperglycaemia, Catatonia, Left Ventricular Hypertrophy, Delirium, Syncope, Left Ventricular Dysfunction, Psychotic Disorder, Sepsis, Dizziness, Electrocardiogram ST Segment Elevation, Myocardial Infarction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 400 mg
    Indication: Schizophrenia
    Start date: 1994-08-05
    End date: 2010-11-09

Clozaril
    Dosage: 100 mg, bid
    Start date: 2012-01-01

Clozaril
    Dosage: 150 mg
    Start date: 2011-03-20

Clozaril
    Dosage: 500 mg
    Administration route: Oral
    Start date: 2010-11-01
    End date: 2011-03-20

Clozaril
    Dosage: 175 mg
    End date: 2011-02-10

Other drugs received by patient: Digoxin; Lantus; Beta Blocking Agents; Lorazepam; Metformin HCL; Insulin; Rosuvastatin; Aripiprazole; Ramipril; Coloxyl with Senna; Duloxetime Hydrochloride; Bisoprolol Fumarate; Furosemide; Pantoprazole; Digoxin; Chlorpromazine HCL; Vitamin D; Aspirin; Olanzapine; Risperidone; Clopidogrel



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-17

Patient: male

Reactions: Hepatitis C, Anaemia, Platelet Count Decreased, Neutropenia, Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Cogentin; Haldol; Elavil; Valproate Sodium



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-17

Patient: female

Reactions: Cachexia, Death, White Blood Cell Count Decreased, Lung Neoplasm Malignant, Neutrophil Count Decreased, Metastases To Central Nervous System, Terminal State

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a physician from Canada on 2012-08-16

Patient: male

Reactions: Hepatitis C, Anaemia, Platelet Count Decreased, Neutropenia, Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Valproate Sodium; Elavil; Haldol; Cogentin



Possible Clozaril side effects in 49 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-14

Patient: 49 year old female

Reactions: White Blood Cell Count Decreased, Eosinophil Count Decreased, Scratch, Tooth Infection, Road Traffic Accident, Neutropenia, Injury, Toothache, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 75 mg, unknown
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-01-12
    End date: 2012-01-17

Clozaril
    Dosage: 25 mg, unknown
    Administration route: Oral
    Start date: 2012-01-12

Clozaril
    Dosage: 650 mg, unknown
    Administration route: Oral
    Start date: 2006-08-14
    End date: 2012-01-09

Mirtazapine
    Dosage: 45 mg, daily
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, daily
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Amoxicillin; Zopiclone



Possible Clozaril side effects in 49 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-13

Patient: 49 year old female

Reactions: Eosinophil Count Decreased, Scratch, White Blood Cell Count Decreased, Tooth Infection, Road Traffic Accident, Injury, Toothache, Neutropenia, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 650 mg, qd
    Administration route: Oral
    Start date: 2006-08-14
    End date: 2012-01-09

Clozaril
    Dosage: unk
    Administration route: Oral
    Start date: 2012-01-12

Clozaril
    Dosage: unk
    Indication: Schizophrenia
    Start date: 2012-01-12
    End date: 2012-01-17

Clozaril
    Dosage: unk

Mirtazapine
    Dosage: 45 mg, qd
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21

Topiramate
    Indication: Schizophrenia

Topiramate

Zispine
    Dosage: 45 mg, qd
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Zispine
    Indication: Depression

Other drugs received by patient: Quetiapine Fumarate; Zopiclone; Amoxicillin



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-13

Patient: female

Reactions: Colon Cancer, Metastases To Liver

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Indication: Schizoaffective Disorder Depressive Type
    Start date: 2001-10-26

Clozaril
    Dosage: 325 mg, daily
    Administration route: Oral
    Start date: 2002-01-01



Possible Clozaril side effects in 49 year old female

Reported by a physician from United Kingdom on 2012-08-13

Patient: 49 year old female

Reactions: Eosinophil Count Decreased, White Blood Cell Count Decreased, Scratch, Tooth Infection, Road Traffic Accident, Injury, Toothache, Neutropenia, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 650 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-08-14
    End date: 2012-01-09

Clozaril

Clozaril
    Dosage: 75 mg, unk
    Start date: 2012-01-12
    End date: 2012-01-17

Mirtazapine
    Dosage: 45 mg, unk
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, unk
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21



Possible Clozaril side effects in female

Reported by a physician from Canada on 2012-08-10

Patient: female

Reactions: Colon Cancer, Metastases To Liver

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Indication: Schizoaffective Disorder Depressive Type
    Start date: 2001-10-26

Clozaril
    Dosage: 325 mg, daily
    Administration route: Oral
    Start date: 2002-01-01



Possible Clozaril side effects in

Reported by a physician from United Kingdom on 2012-08-10

Patient:

Reactions: White Blood Cell Count Decreased, Eosinophil Count Decreased, Scratch, Tooth Infection, Road Traffic Accident, Toothache, Neutropenia, Injury, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 75 mg, unk
    Administration route: Oral
    Start date: 2012-01-12
    End date: 2012-01-17

Clozaril
    Dosage: 650 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-08-14
    End date: 2012-01-09

Clozaril
    Dosage: unk
    Administration route: Oral

Mirtazapine
    Dosage: 45 mg, qd
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Amoxicillin; Zopiclone; Quetiapine Fumarate



Possible Clozaril side effects in 49 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-08

Patient: 49 year old female

Reactions: Scratch, Eosinophil Count Decreased, White Blood Cell Count Decreased, Tooth Infection, Off Label Use, Road Traffic Accident, Platelet Count Decreased, Injury, Neutropenia, Toothache

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 75 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-01-12
    End date: 2012-01-17

Mirtazapine
    Dosage: 45 mg, qd
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Quetiapine Fumarate; Zopiclone; Antibiotics; Amoxicillin



Possible Clozaril side effects in 59 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-06

Patient: 59 year old male, weighing 117.0 kg (257.4 pounds)

Reactions: Tracheobronchitis, Anxiety, Urinary Incontinence, Faecal Incontinence, Atrial Fibrillation, Neuroleptic Malignant Syndrome, Deep Vein Thrombosis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in 49 year old female

Reported by a physician from Denmark on 2012-08-06

Patient: 49 year old female

Reactions: White Blood Cell Count Decreased, Scratch, Laceration, Tooth Infection, Road Traffic Accident, Platelet Count Decreased, Toothache, Neutropenia, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 650 mg, qd, po
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-08-14
    End date: 2012-01-17

Mirtazapine
    Dosage: 45 mg, qd, po
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd, po
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Zopiclone; Amoxicillin



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-05

Patient: female

Reactions: White Blood Cell Count Decreased, Scratch, Eosinophil Count Decreased, Tooth Infection, Road Traffic Accident, Neutropenia, Injury, Toothache, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 75 mg, unk
    Administration route: Oral
    Start date: 2012-01-12
    End date: 2012-01-17

Clozaril
    Dosage: 650 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-08-14
    End date: 2012-01-09

Mirtazapine
    Dosage: 45 mg, unk
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21



Possible Clozaril side effects in 49 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-03

Patient: 49 year old female

Reactions: Scratch, White Blood Cell Count Decreased, Eosinophil Count Decreased, Tooth Infection, Road Traffic Accident, Toothache, Injury, Neutropenia, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 650 mg, qd
    Administration route: Oral
    Start date: 2006-08-14
    End date: 2012-01-09

Clozaril
    Dosage: unk
    Indication: Schizophrenia
    Start date: 2012-01-12
    End date: 2012-01-17

Clozaril
    Dosage: unk

Clozaril
    Dosage: unk
    Administration route: Oral
    Start date: 2012-01-12

Mirtazapine
    Dosage: 45 mg, qd
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Mirtazapine
    Indication: Depression

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21

Topiramate
    Indication: Schizophrenia

Other drugs received by patient: Amoxicillin; Zopiclone



Possible Clozaril side effects in 49 year old female

Reported by a physician from United Kingdom on 2012-08-03

Patient: 49 year old female

Reactions: Eosinophil Count Decreased, Scratch, White Blood Cell Count Decreased, Tooth Infection, Off Label Use, Road Traffic Accident, Platelet Count Decreased, Toothache, Neutropenia, Injury, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Administration route: Oral

Clozaril
    Administration route: Oral

Clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-01-12
    End date: 2012-01-17

Clozaril
    Administration route: Oral
    Start date: 2006-08-14
    End date: 2012-01-09

Mirtazapine
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-01-01
    End date: 2012-01-21

Topiramate
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Amoxicillin; Zopiclone; Quetiapine Fumarate



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-03

Patient: female

Reactions: Agitation, Atelectasis, White Blood Cell Count Decreased, Hepatic Function Abnormal, Pleurisy, Pyrexia, Thirst, Aggression, Irritability, C-Reactive Protein Increased, Platelet Count Decreased, Pleural Effusion, Anger, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 100 mg
    Administration route: Oral
    Start date: 2010-08-18
    End date: 2010-08-20

Clozaril
    Dosage: 175 mg
    Administration route: Oral
    Start date: 2010-08-15
    End date: 2010-08-17

Clozaril
    Dosage: 12.5 mg
    Indication: Schizophrenia

Clozaril
    Dosage: 50 mg
    Administration route: Oral
    Start date: 2010-07-30
    End date: 2010-08-01

Clozaril
    Dosage: 25 mg daily
    Administration route: Oral
    Start date: 2010-07-29
    End date: 2010-07-29

Clozaril
    Administration route: Oral
    Start date: 2010-08-02
    End date: 2010-08-04

Clozaril
    Dosage: 75 mg
    Administration route: Oral
    Start date: 2010-08-05
    End date: 2010-08-06

Clozaril
    Dosage: 5 mg
    Administration route: Oral
    Start date: 2010-09-10
    End date: 2010-09-14

Clozaril
    Dosage: 100 mg
    Administration route: Oral
    Start date: 2010-08-07
    End date: 2010-08-08

Clozaril
    Dosage: 125 mg
    Administration route: Oral
    Start date: 2010-08-09
    End date: 2010-08-11

Clozaril
    Dosage: 150 mg
    Administration route: Oral
    Start date: 2010-08-12
    End date: 2010-08-14

Other drugs received by patient: Perphenazine; Risperidone; Perospirone Hydrochloride; Levomepromazine Maleate; Akineton; Quetiapine Fumarate; Depakene; Pursennide; Olanzapine; Olanzapine; Lexotan; Silece; Depakene; Bromperidol; Levomepromazine Maleate; Levomepromazine Maleate; Meilax; Almarl; Magmitt; Levomepromazine Maleate; Akineton; Magmitt; Timiperone; Aripiprazole; Blonanserin; Levomepromazine Maleate; Olanzapine; Silece; Akineton; Meilax; Silece



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-03

Patient: female

Reactions: Scratch, White Blood Cell Count Decreased, Eosinophil Count Decreased, Tooth Infection, Road Traffic Accident, Neutropenia, Injury, Toothache, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozaril
    Dosage: 650 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-08-14
    End date: 2012-01-09

Clozaril
    Dosage: 75 mg, unk
    Administration route: Oral
    Start date: 2012-01-12
    End date: 2012-01-17

Mirtazapine
    Dosage: 45 mg, unk
    Administration route: Oral
    Indication: Depressive Symptom
    Start date: 2006-01-01
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2007-01-01
    End date: 2012-01-21



Possible Clozaril side effects in male

Reported by a physician from Japan on 2012-08-01

Patient: male, weighing 54.0 kg (118.8 pounds)

Reactions: Renal Disorder, Hypotension, Pyrexia, Cardiomyopathy, Left Ventricular Failure, Eating Disorder, Ileus Paralytic, Delusion, C-Reactive Protein Increased, Dehydration, Pulmonary Congestion, Ejection Fraction Decreased, Hyperphosphatasaemia, Myocarditis, Shock

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 12.5 mg, unk
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    Start date: 2012-04-10
    End date: 2012-04-10

Clozaril
    Dosage: 100 mg, daily
    Administration route: Oral
    Start date: 2012-04-18
    End date: 2012-04-19

Clozaril
    Dosage: 25 mg, daily
    Administration route: Oral
    Start date: 2012-04-11
    End date: 2012-04-12

Clozaril
    Dosage: 100 mg, unk
    Administration route: Oral
    Start date: 2012-04-25
    End date: 2012-04-25

Clozaril
    Dosage: 75 mg, unk
    Administration route: Oral
    Start date: 2012-04-16
    End date: 2012-04-17

Clozaril
    Dosage: 50 mg, unk
    Start date: 2012-04-26
    End date: 2012-04-26

Clozaril
    Dosage: 125 mg, daily
    Administration route: Oral
    Start date: 2012-04-20
    End date: 2012-04-22

Clozaril
    Dosage: 50 mg, unk
    Administration route: Oral
    Start date: 2012-04-13
    End date: 2012-04-15

Clozaril
    Dosage: 150 mg, unk
    Administration route: Oral
    Start date: 2012-04-23
    End date: 2012-04-24

Voltaren
    Dosage: 25 mg, 4 times per day
    Start date: 2012-04-24
    End date: 2012-04-27

Other drugs received by patient: Lamictal; Lamictal; Lamictal; Zyprexa; Zyprexa; Lithium Carbonate; Famotidine



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