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Clozaril (Clozapine) - Overdose - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Overdose ()

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clozaril (Clozapine) where reactions include overdose. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of    Next >>

Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-08-27

Patient: male, weighing 62.0 kg (136.4 pounds)

Reactions: Overdose, Depression, Schizophrenia, Paranoid Type, Loss of Consciousness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 375 mg, qd
    Start date: 2012-07-03

Clozaril
    Dosage: 4 to 6 tablets
    Start date: 2012-06-29

Clozaril
    Dosage: 375 mg, daily
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2011-08-20

Other drugs received by patient: Paroxetine HCL; Simvastatin; Atenolol; Doxazosin Mesylate; Amisulpride; Aripiprazole



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-21

Patient: female

Reactions: Blood Creatine Phosphokinase Increased, Pneumonia, Neutrophil Count Increased, Overdose, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, (mixed tablet) which included clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Zocor
    Dosage: 40 mixed tablets
    Administration route: Oral



Possible Clozaril side effects in 46 year old female

Reported by a physician from United Kingdom on 2012-08-17

Patient: 46 year old female

Reactions: Overdose, Blood Creatine Phosphokinase Increased, Neutrophil Count Increased, Pneumonia, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Clozaril side effects in 46 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-17

Patient: 46 year old female

Reactions: Neutrophil Count Increased, Overdose, Pneumonia, Blood Creatine Phosphokinase Increased, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, (mixed tablet) which included clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: 40 mixed tablets
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Clozaril side effects in 46 year old female

Reported by a physician from United Kingdom on 2012-08-14

Patient: 46 year old female

Reactions: Neutrophil Count Increased, Blood Creatine Phosphokinase Increased, Overdose, Pneumonia, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, (mixed tablet) which included clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: 40 mixed tablets
    Administration route: Oral



Possible Clozaril side effects in 46 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-14

Patient: 46 year old female

Reactions: Blood Creatine Phosphokinase Increased, Overdose, Pneumonia, Blood Urea Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, (mixed tablet) which included clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: 40 mixed tablets
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Clozaril side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-10

Patient:

Reactions: Overdose, Blood Creatine Phosphokinase Increased, Pneumonia, Neutrophil Count Increased, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Zocor
    Administration route: Oral



Possible Clozaril side effects in 46 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-07

Patient: 46 year old female

Reactions: Overdose, Neutrophil Count Increased, Pneumonia, Blood Creatine Phosphokinase Increased, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, (mixed tablet) which included clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: 40 mixed tablets
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Clozaril side effects in male

Reported by a pharmacist from United Kingdom on 2012-08-06

Patient: male, weighing 119.0 kg (261.8 pounds)

Reactions: Increased Appetite, Diabetes Mellitus, Psychomotor Retardation, Schizophrenia, Headache, Constipation, Suicidal Ideation, Weight Increased, Speech Disorder, Overdose, Fatigue, Palpitations, Chest Pain, Hallucination, Hypertensive Heart Disease, Schizoaffective Disorder, Hyperlipidaemia, Anxiety, Affective Disorder, Sleep Disorder, Disturbance in Attention, Feeling Abnormal, Respiratory Tract Infection, Depressed Mood

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Indication: Schizophrenia
    Start date: 2005-12-01

Clozaril
    Dosage: 325 mg, qd
    Start date: 2008-03-01

Clozaril
    Dosage: 350 mg, qd
    End date: 2010-01-01

Clozaril
    Dosage: 375 mg, qd

Clozaril
    Start date: 2006-01-25

Clozaril
    Dosage: 350 mg, qd

Clozaril
    Dosage: 250 mg, qd
    Start date: 2011-03-01

Clozaril
    Dosage: 225 mg, qd

Clozaril
    Dosage: 300 mg, qd

Other drugs received by patient: Aripiprazole; Depakote; Quetiapine; Escitalopram; Valproate Sodium; Diazepam; Clopixol; Depakote; Amisulpride; Risperidone; Haloperidol; Stelazine; Fluoxetine HCL; Duloxetime Hydrochloride; Citalopram Hydrobromide



Possible Clozaril side effects in 46 year old female

Reported by a physician from United Kingdom on 2012-08-06

Patient: 46 year old female

Reactions: Blood Creatine Phosphokinase Increased, Pneumonia, Overdose, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Clozaril side effects in 46 year old female

Reported by a physician from United Kingdom on 2012-08-06

Patient: 46 year old female

Reactions: Blood Creatine Phosphokinase Increased, Neutrophil Count Increased, Pneumonia, Overdose, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, (mixed tablet) which included clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: 40 mixed tablets
    Administration route: Oral



Possible Clozaril side effects in 46 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-03

Patient: 46 year old female

Reactions: Overdose, Neutrophil Count Increased, Blood Creatine Phosphokinase Increased, Pneumonia, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Clozaril side effects in 46 year old female

Reported by a physician from United Kingdom on 2012-08-01

Patient: 46 year old female

Reactions: Blood Creatine Phosphokinase Increased, Pneumonia, Overdose, Blood Urea Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, (mixed tablet) which included clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: 40 mixed tablets
    Administration route: Oral



Possible Clozaril side effects in female

Reported by a physician from United Kingdom on 2012-08-01

Patient: female

Reactions: Neutrophil Count Increased, Blood Creatine Phosphokinase Increased, Pneumonia, Overdose, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, (mixed tablet) which included clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: 40 mixed tablets
    Administration route: Oral



Possible Clozaril side effects in

Reported by a consumer/non-health professional from United Kingdom on 2012-07-26

Patient:

Reactions: Blood Creatine Phosphokinase Increased, Neutrophil Count Increased, Pneumonia, Overdose, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Zocor
    Administration route: Oral



Possible Clozaril side effects in female

Reported by a physician from United Kingdom on 2012-07-19

Patient: female

Reactions: Overdose, Blood Creatine Phosphokinase Increased, Pneumonia, Neutrophil Count Increased, Blood Urea Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 40 df, (mixed tablet) which included clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-04-28
    End date: 2012-06-28

Simvastatin
    Dosage: 40 mixed tablets
    Administration route: Oral



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-07-16

Patient: male

Reactions: Agitation, Confusional State, Vomiting, Antipsychotic Drug Level Increased, Restlessness, Encephalitis, Overdose, Circulatory Collapse

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Haloperidol; Procyclidine Hydrochloride 2MG TAB; Acetaminophen



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-11

Patient: male

Reactions: Agitation, Confusional State, Overdose, Vomiting, Restlessness, Circulatory Collapse, Encephalitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Procyclidine Hydrochloride 2MG TAB; Haloperidol; Acetaminophen



Possible Clozaril side effects in female

Reported by a physician from United Kingdom on 2012-07-10

Patient: female

Reactions: Overdose, Mental Disorder, Antipsychotic Drug Level Above Therapeutic, Epilepsy

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Dosage: unk ukn, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2002-06-27

Clozaril
    Dosage: 650 mg, daily
    Administration route: Oral
    Start date: 2003-01-01

Other drugs received by patient: Depakote; Zopiclone; Clomipramine HCL; Carbamazepine



Possible Clozaril side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-05

Patient: 47 year old male

Reactions: Neutrophil Count Increased, Pneumonia Aspiration, Overdose, C-Reactive Protein Increased, Respiratory Arrest, White Blood Cell Count Increased, Lower Respiratory Tract Infection

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-05-01

Clozaril
    Dosage: unk
    Start date: 2012-05-25

Lorazepam
    Dosage: 1 mg, prn
    Administration route: Oral
    Indication: Anxiety
    Start date: 2012-04-30

Nitrazepam
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Zopiclone
    Dosage: unk
    Administration route: Oral
    Indication: Insomnia
    Start date: 2012-04-30

Other drugs received by patient: Olanzapine



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-07-03

Patient: male

Reactions: Pupillary Reflex Impaired, Overdose, Somnolence

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 425 mg, single at night
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2009-07-06

Clozaril
    Dosage: 3 x 425 mg
    Start date: 2012-06-25



Possible Clozaril side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-27

Patient: 47 year old male

Reactions: Neutrophil Count Increased, Overdose, Pneumonia Aspiration, C-Reactive Protein Increased, Respiratory Arrest, Lower Respiratory Tract Infection, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-05-01

Clozaril
    Dosage: unk
    Start date: 2012-05-25

Lorazepam
    Dosage: 1 mg, prn
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-04-30

Nitrazepam
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Zopiclone (Unknown)
    Dosage: 7.5 mg, daily
    Administration route: Oral
    Indication: Insomnia
    Start date: 2012-04-30

Other drugs received by patient: Benzodiazepine Derivatives; Olanzapine



Possible Clozaril side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-25

Patient: 47 year old male

Reactions: Neutrophil Count Increased, Pneumonia Aspiration, Overdose, C-Reactive Protein Increased, Respiratory Arrest, Lower Respiratory Tract Infection, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: unk
    Start date: 2012-05-25

Clozaril
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-05-01

Lorazepam
    Dosage: 1 mg, prn
    Administration route: Oral
    Indication: Anxiety
    Start date: 2012-04-30

Nitrazepam
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Zopiclone
    Dosage: unk
    Administration route: Oral
    Indication: Insomnia
    Start date: 2012-04-30

Other drugs received by patient: Olanzapine



Possible Clozaril side effects in 41 year old female

Reported by a physician from United Kingdom on 2012-06-22

Patient: 41 year old female

Reactions: Overdose, Pneumonia, Diabetes Mellitus, Respiratory Depression, Somnolence, Chronic Obstructive Pulmonary Disease, Convulsion

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Administration route: Oral
    Indication: Intentional Self-Injury
    Start date: 2006-05-25
    End date: 2012-03-01

Clozaril
    Dosage: 175 mg int morning and 275 mg at night
    End date: 2012-03-18

Diazepam

Other drugs received by patient: Lithium; Pioglitazone; Valproate Sodium; Simvastatin; Venlafaxine HCL; Lansoprazole; Metformin HCL



Possible Clozaril side effects in female

Reported by a physician from United Kingdom on 2012-06-22

Patient: female

Reactions: Overdose, Pneumothorax, Depressed Level of Consciousness, Coma Scale Abnormal, Cardiac Arrest

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Symbicort; Albuterol; Mirtazapine; Folic Acid; Ramipril; Simvastatin; Procyclidine Hydrochloride 2MG TAB; Diazepam



Possible Clozaril side effects in female

Reported by a physician from United States on 2012-06-22

Patient: female, weighing 65.3 kg (143.7 pounds)

Reactions: Confusional State, Overdose, Respiratory Distress, Convulsion

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Citalopram Hydrobromide; Lortab; Klonopin; Klonopin; Lyrica; Lortab; Neurontin; Prilosec



Possible Clozaril side effects in 41 year old female

Reported by a pharmacist from Denmark on 2012-06-21

Patient: 41 year old female

Reactions: Pneumonia, Overdose, Diabetes Mellitus, Respiratory Depression, Somnolence, Chronic Obstructive Pulmonary Disease, Convulsion

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 500 mg;po
    Administration route: Oral
    Indication: Intentional Self-Injury

Diazepam

Other drugs received by patient: Lithium Carbonate; Simvastatin; Venlafaxine; Lansoprazole; Valproic Acid; Metformin HCL; Pioglitazone



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-06-20

Patient: male

Reactions: Neutrophil Count Increased, Pneumonia Aspiration, Lower Respiratory Tract Infection, Overdose, C-Reactive Protein Increased, Respiratory Arrest, Multiple Drug Overdose, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: unk ukn, unk
    Start date: 2012-05-25

Clozaril
    Dosage: unk ukn, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-05-01

Lorazepam
    Dosage: 1 mg, prn
    Administration route: Oral
    Start date: 2012-04-30

Nitrazepam
    Administration route: Oral

Zopiclone
    Dosage: 7.5 mg, daily
    Administration route: Oral
    Indication: Insomnia
    Start date: 2012-04-30

Other drugs received by patient: Benzodiazepines; Olanzapine



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-19

Patient: male

Reactions: Pneumonia Aspiration, Neutrophil Count Increased, Overdose, C-Reactive Protein Increased, Respiratory Arrest, Lower Respiratory Tract Infection, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: unk ukn, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-05-01

Clozaril
    Dosage: unk ukn, unk
    Start date: 2012-05-25

Lorazepam
    Dosage: 1 mg, prn
    Administration route: Oral
    Start date: 2012-04-30

Nitrazepam
    Administration route: Oral

Zopiclone
    Dosage: 7.5 mg, daily
    Administration route: Oral
    Indication: Insomnia
    Start date: 2012-04-30

Other drugs received by patient: Benzodiazepines; Olanzapine



Possible Clozaril side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-19

Patient: 47 year old male

Reactions: Pneumonia Aspiration, Overdose, Respiratory Arrest

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-05-01

Lorazepam
    Dosage: 1 mg, prn
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-04-30

Nitrazepam
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Zopiclone (Unknown)
    Dosage: 7.5 mg, daily
    Administration route: Oral
    Indication: Insomnia
    Start date: 2012-04-30

Other drugs received by patient: Benzodiazepine Derivatives; Olanzapine



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