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Clozaril (Clozapine) - Myocardial Infarction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Myocardial Infarction ()

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clozaril (Clozapine) where reactions include myocardial infarction. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of    Next >>

Possible Clozaril side effects in female

Reported by a physician from Australia on 2012-08-20

Patient: female

Reactions: Electrocardiogram QT Prolonged, Confusional State, Urinary Tract Infection, Hyperglycaemia, Catatonia, Left Ventricular Hypertrophy, Delirium, Syncope, Left Ventricular Dysfunction, Psychotic Disorder, Sepsis, Dizziness, Electrocardiogram ST Segment Elevation, Myocardial Infarction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 400 mg
    Indication: Schizophrenia
    Start date: 1994-08-05
    End date: 2010-11-09

Clozaril
    Dosage: 100 mg, bid
    Start date: 2012-01-01

Clozaril
    Dosage: 150 mg
    Start date: 2011-03-20

Clozaril
    Dosage: 500 mg
    Administration route: Oral
    Start date: 2010-11-01
    End date: 2011-03-20

Clozaril
    Dosage: 175 mg
    End date: 2011-02-10

Other drugs received by patient: Digoxin; Lantus; Beta Blocking Agents; Lorazepam; Metformin HCL; Insulin; Rosuvastatin; Aripiprazole; Ramipril; Coloxyl with Senna; Duloxetime Hydrochloride; Bisoprolol Fumarate; Furosemide; Pantoprazole; Digoxin; Chlorpromazine HCL; Vitamin D; Aspirin; Olanzapine; Risperidone; Clopidogrel



Possible Clozaril side effects in male

Reported by a physician from Canada on 2012-08-09

Patient: male

Reactions: Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in female

Reported by a physician from Australia on 2012-08-06

Patient: female

Reactions: Myocardial Ischaemia, Left Ventricular Hypertrophy, Diastolic Dysfunction, Tricuspid Valve Incompetence, Cardiac Disorder, Obesity, Electrocardiogram Abnormal, Hypertension, Myocardial Infarction

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in female

Reported by a pharmacist from Canada on 2012-07-25

Patient: female

Reactions: Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Administration route: Oral
    Indication: Dementia
    Start date: 2008-06-12

Clozaril
    Dosage: 75 mg, daily
    Administration route: Oral

Other drugs received by patient: Alphagan; Ibuprofen; Vitamin D; Effexor; Tryptophan; Calcium; Pantoprazole Sodium; Actonel; Timoptic; Motilium; Sorbitol 50pc INJ; Altace; Senokot; Sinemet; B12 ^recip^



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-07-18

Patient: male, weighing 105.0 kg (231.0 pounds)

Reactions: Chest Pain, Myocardial Infarction, Electrocardiogram ST Segment Elevation, Renal Artery Stenosis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-04-06

Clozaril
    Administration route: Oral
    Start date: 2012-06-14

Other drugs received by patient: Duloxetime Hydrochloride; Aspirin; Gliclazide; Metformin Hydrochloride; Sitagliptin; Metformin Hydrochloride; Omeprazole; Metformin Hydrochloride; Simvastatin



Possible Clozaril side effects in female

Reported by a physician from Australia on 2012-07-13

Patient: female

Reactions: Electrocardiogram Abnormal, Left Ventricular Hypertrophy, Diastolic Dysfunction, Tricuspid Valve Incompetence, Myocardial Infarction, Cardiac Disorder

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a physician from NEW Zealand on 2012-07-12

Patient: male

Reactions: Circulatory Collapse, Constipation, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a pharmacist from United Kingdom on 2012-07-02

Patient: male

Reactions: Weight Increased, Hypertensive Heart Disease, Coronary Artery Disease, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Lansoprazole; Lorazepam; Simvastatin; Pirenzepine; Sertraline Hydrochloride; Lamotrigine; Docusate Sodium



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-29

Patient: female

Reactions: Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in female

Reported by a physician from Australia on 2012-06-26

Patient: female

Reactions: Confusional State, Electrocardiogram QT Prolonged, Hyperglycaemia, Urinary Tract Infection, Left Ventricular Hypertrophy, Catatonia, Delirium, Left Ventricular Dysfunction, Syncope, Psychotic Disorder, Sepsis, Electrocardiogram Abnormal, Dizziness, Electrocardiogram ST Segment Elevation, Myocardial Infarction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 150 mg, unk
    Start date: 2011-03-20

Clozaril
    Dosage: 100 mg, bid
    Start date: 2012-01-01

Clozaril
    Dosage: 175 mg, unk
    End date: 2011-02-10

Clozaril
    Dosage: 400 mg
    Indication: Schizophrenia
    Start date: 1994-08-05

Clozaril
    Dosage: 500 mg
    Administration route: Oral
    Start date: 2010-11-01
    End date: 2011-03-20

Other drugs received by patient: Ramipril; Furosemide; Metformin HCL; Lantus; Aspirin; Beta Blocking Agents; Insulin; Vitamin D; Pantoprazole; Clopidogrel; Digoxin; Aripiprazole; Coloxyl with Senna; Duloxetime Hydrochloride; Olanzapine; Chlorpromazine HCL; Bisoprolol Fumarate; Rosuvastatin; Risperidone



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-06-18

Patient: male

Reactions: Weight Increased, Hypertensive Heart Disease, Coronary Artery Disease, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Lamotrigine; Simvastatin



Possible Clozaril side effects in female

Reported by a physician from United Kingdom on 2012-06-12

Patient: female

Reactions: Death, Mental Impairment, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-06-11

Patient: male

Reactions: Antipsychotic Drug Level Below Therapeutic, Obesity, Blood Cholesterol Increased, Myocardial Infarction, White Blood Cell Count Increased

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Dosage: 325 mg, daily
    Administration route: Oral

Clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2001-07-01

Other drugs received by patient: Citalopram



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-24

Patient: female

Reactions: Mental Impairment, Death, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-16

Patient: male

Reactions: Coronary Artery Thrombosis, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Sertraline Hydrochloride



Possible Clozaril side effects in male

Reported by a pharmacist from Ireland on 2012-05-03

Patient: male

Reactions: Dyspnoea, Chest Pain, Myocardial Infarction, Cardiac Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 100mg mane 175mg nocte
    Administration route: Oral

Clozaril
    Dosage: 150 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-12-16

Clozaril
    Dosage: 175 mg, unk
    Administration route: Oral
    End date: 2012-02-01

Other drugs received by patient: Aspirin; Atorvastatin Calcium; Lansoprazole; Venlafaxine; Ramipril; Furosemide; Clopidogrel



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-04-26

Patient: male

Reactions: Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in female

Reported by a physician from Japan on 2012-04-17

Patient: female, weighing 65.0 kg (143.0 pounds)

Reactions: Pyrexia, Asphyxia, Cardio-Respiratory Arrest, RED Blood Cell Count Decreased, Aspiration, Abdominal Distension, Myocardial Infarction, White Blood Cell Count Increased, Blood Glucose Increased, Lymphocyte Count Decreased, Vomiting, Neutrophil Count Increased, Intestinal Obstruction, Haemoglobin Decreased, Diarrhoea, Gastrointestinal Disorder, Influenza A Virus Test Positive

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Dosage: 500 mg, daily
    Administration route: Oral
    Start date: 2011-09-23
    End date: 2011-12-01

Clozaril
    Dosage: 600 mg, daily
    Administration route: Oral
    Start date: 2011-12-02

Clozaril
    Dosage: 12.5 mg, daily
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-07-08
    End date: 2011-07-08

Clozaril
    Dosage: 325 mg, daily
    Administration route: Oral
    Start date: 2011-08-12
    End date: 2011-08-18

Clozaril
    Dosage: 175 mg, daily
    Administration route: Oral
    Start date: 2011-08-01
    End date: 2011-08-03

Clozaril
    Dosage: 75 mg, daily
    Administration route: Oral
    Start date: 2011-07-22
    End date: 2011-07-23

Clozaril
    Dosage: 100 mg, daily
    Administration route: Oral
    Start date: 2011-07-24
    End date: 2011-07-25

Clozaril
    Dosage: 400 mg, daily
    Administration route: Oral
    Start date: 2011-08-19
    End date: 2011-09-22

Clozaril
    Dosage: 50 mg, daily
    Administration route: Oral
    Start date: 2011-07-12
    End date: 2011-07-21

Clozaril
    Dosage: 150 mg, daily
    Administration route: Oral
    Start date: 2011-07-29
    End date: 2011-07-31

Clozaril
    Dosage: 125 mg, daily
    Administration route: Oral
    Start date: 2011-07-26
    End date: 2011-07-28

Clozaril
    Dosage: 300 mg, daily
    Administration route: Oral
    Start date: 2011-08-05
    End date: 2011-08-11

Clozaril
    Dosage: 25 mg, daily
    Administration route: Oral
    Start date: 2011-07-09
    End date: 2011-07-11

Clozaril
    Dosage: 200 mg, daily
    Administration route: Oral
    Start date: 2011-08-04
    End date: 2011-08-04

Other drugs received by patient: Lorazepam; Leucon; Tsumura DAI-Kenchu-TO; Rohypnol; Setous; Setous; Sennoside; Lithium Carbonate; Ferrous Sulfate TAB; Zyprexa; Zyprexa; Setous; Levotomin; Acetaminophen; Tsumura DAI-Kenchu-TO; Paxil; Ferrous Sulfate TAB; Medicon (Dextromethorphan Hydrobromide); Bladderon; Terbinafine HCL; Zyprexa; Magnesium Oxide; Doral; Risperdal



Possible Clozaril side effects in female

Reported by a physician from Canada on 2012-04-09

Patient: female

Reactions: Pneumonia, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Aspirin; Oxazepam; Sertraline Hydrochloride; Furosemide; Aricept; Cisapride



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from NEW Zealand on 2012-04-02

Patient: male

Reactions: Dyspnoea, Unresponsive To Stimuli, Parkinson's Disease, Hyperhidrosis, Loss of Consciousness, Anxiety, Fatigue, Haematocrit Decreased, RED Blood Cell Count Decreased, Pulse Pressure Decreased, Heart Rate Irregular, Cardiac Arrest, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-08-23

Clozaril
    Dosage: 62.5 mg, nocte
    Administration route: Oral
    Start date: 2011-12-01



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-03-26

Patient: male

Reactions: Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-03-26

Patient: male

Reactions: Nephrolithiasis, Myocardial Ischaemia, Parkinson's Disease, Atrial Fibrillation, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from Ireland on 2012-03-26

Patient: male

Reactions: Death, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Dosage: 175 mg mane + 300 mg nocte
    Start date: 2011-06-28

Clozaril
    Indication: Schizophrenia
    Start date: 2010-01-19

Clozaril
    Start date: 2011-01-21

Other drugs received by patient: Inderal; Lexapro; Dalmane; Mirtazapine



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-03-20

Patient: male, weighing 107.0 kg (235.4 pounds)

Reactions: Incontinence, Obsessive-Compulsive Disorder, Cyanosis, Oedema Peripheral, Myocardial Ischaemia, Hypertensive Heart Disease, Hypothyroidism, Arteriosclerosis Coronary Artery, Myocardial Infarction, Arrhythmia

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Dosage: unk ukn, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 1998-07-07

Clozaril
    Dosage: 375 mg, daily
    Administration route: Oral
    Start date: 2008-01-01

Clozaril
    Dosage: 75 mg, daily at morning

Other drugs received by patient: Senna; Indapamide; Losartan Potassium; Lercanidipine; Levothyroxine Sodium; Fluoxetine; Calcium Channel Blockers



Possible Clozaril side effects in 30 year old female

Reported by a physician from United Kingdom on 2012-03-12

Patient: 30 year old female

Reactions: Bipolar Disorder, Ventricular Fibrillation, Cardiac Arrest, Myocardial Infarction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: tabs
    Administration route: Oral
    Start date: 2011-10-05

Aripiprazole

Yasmin

Other drugs received by patient: Depakote



Possible Clozaril side effects in female

Reported by a physician from Canada on 2012-03-12

Patient: female

Reactions: Death, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-03-09

Patient: female

Reactions: Death, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in female

Reported by a physician from Japan on 2012-03-05

Patient: female, weighing 65.0 kg (143.0 pounds)

Reactions: Pyrexia, Asphyxia, Cardio-Respiratory Arrest, Aspiration, RED Blood Cell Count Decreased, Abdominal Distension, Myocardial Infarction, Lymphocyte Count Decreased, White Blood Cell Count Increased, Blood Glucose Increased, Vomiting, Neutrophil Count Increased, Intestinal Obstruction, Haemoglobin Decreased, Diarrhoea, Gastrointestinal Disorder, Influenza A Virus Test Positive

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Dosage: 100 mg, daily
    Administration route: Oral
    Start date: 2011-07-24
    End date: 2011-07-25

Clozaril
    Dosage: 200 mg, daily
    Administration route: Oral
    Start date: 2011-08-04
    End date: 2011-08-04

Clozaril
    Dosage: 300 mg, daily
    Administration route: Oral
    Start date: 2011-08-05
    End date: 2011-08-11

Clozaril
    Dosage: 25 mg, daily
    Administration route: Oral
    Start date: 2011-07-09
    End date: 2011-07-11

Clozaril
    Dosage: 400 mg, daily
    Administration route: Oral
    Start date: 2011-08-19
    End date: 2011-09-22

Clozaril
    Dosage: 600 mg, daily
    Administration route: Oral
    Start date: 2011-12-02

Clozaril
    Dosage: 75 mg, daily
    Administration route: Oral
    Start date: 2011-07-22
    End date: 2011-07-23

Clozaril
    Dosage: 125 mg, daily
    Administration route: Oral
    Start date: 2011-07-26
    End date: 2011-07-28

Clozaril
    Dosage: 12.5 mg, daily
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-07-08
    End date: 2011-07-08

Clozaril
    Dosage: 150 mg, daily
    Administration route: Oral
    Start date: 2011-07-29
    End date: 2011-07-31

Clozaril
    Dosage: 50 mg, daily
    Administration route: Oral
    Start date: 2011-07-12
    End date: 2011-07-21

Clozaril
    Dosage: 175 mg, daily
    Administration route: Oral
    Start date: 2011-08-01
    End date: 2011-08-03

Clozaril
    Dosage: 325 mg, daily
    Administration route: Oral
    Start date: 2011-08-12
    End date: 2011-08-18

Clozaril
    Dosage: 500 mg, daily
    Administration route: Oral
    Start date: 2011-09-23
    End date: 2011-12-01

Other drugs received by patient: Medicon (Dextromethorphan Hydrobromide); Terbinafine HCL; Doral; Leucon; Lithium Carbonate; Bladderon; Levotomin; Acetaminophen; Zyprexa; Risperdal; Rohypnol; Zyprexa; Zyprexa; Setous; Ferrous Sulfate TAB; Setous; Setous; Sennoside; Tsumura DAI-Kenchu-TO; Ferrous Sulfate TAB; Paxil; Lorazepam; Magnesium Oxide; Tsumura DAI-Kenchu-TO



Possible Clozaril side effects in male

Reported by a physician from Ireland on 2012-03-02

Patient: male

Reactions: Dyspnoea, Chest Pain, Myocardial Infarction, Cardiac Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 150 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-12-16

Clozaril
    Dosage: 175 mg, unk
    Administration route: Oral
    End date: 2012-02-01

Clozaril
    Dosage: 275 mg, daily
    Administration route: Oral

Other drugs received by patient: Lansoprazole; Clopidogrel; Furosemide; Ramipril; Aspirin; Atorvastatin Calcium; Venlafaxine



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-02-29

Patient: male, weighing 69.8 kg (153.6 pounds)

Reactions: Respiratory Arrest, Myocardial Infarction, Left Ventricular Failure, Feeling Cold

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril
    Dosage: 600 mg nocte
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2001-04-24

Amisulpride
    Dosage: 100 mg, bid
    Administration route: Oral
    Indication: Schizophrenia

Clozaril
    Dosage: unk df, unk
    Administration route: Oral
    Start date: 2006-11-02

Other drugs received by patient: Lansoprazole



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