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Clozaril (Clozapine) - Mental Impairment - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Mental Impairment (230)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clozaril (Clozapine) where reactions include mental impairment. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 230   Next >>

Possible Clozaril side effects in male

Reported by a physician from Australia on 2012-08-27

Patient: male

Reactions: Mental Impairment

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-08-27

Patient: male

Reactions: Mental Impairment, Colon Cancer, Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-11-01
    End date: 2011-09-29

Clozaril
    Dosage: unk ukn, unk

Other drugs received by patient: Paliperidone; Olanzapine



Possible Clozaril side effects in male

Reported by a physician from NEW Zealand on 2012-08-23

Patient: male

Reactions: Mental Impairment, Dementia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 250 mg
    Indication: Schizophrenia
    Start date: 2006-11-09

Clozaril
    Dosage: 200 mg, unk



Possible Clozaril side effects in male

Reported by a physician from Australia on 2012-08-23

Patient: male, weighing 109.0 kg (239.8 pounds)

Reactions: Electrocardiogram QT Prolonged, Blood Creatine Phosphokinase Increased, Head Injury, Hallucination, Auditory, Pyrexia, Feeling Cold, Myalgia, Fatigue, Malaise, C-Reactive Protein Increased, Chest Pain, Injury, Tenderness, Myoglobin Blood Increased, Myocarditis, White Blood Cell Count Increased, Decreased Appetite, Chest Discomfort, Dyspnoea, Nausea, Tachyarrhythmia, Troponin T Increased, Aggression, Tremor, Affective Disorder, Mental Impairment, Heart Rate Increased, Electrocardiogram Abnormal, Suicide Attempt, Troponin I Increased, Sinus Tachycardia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 325 mg
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    Start date: 2004-08-10

Clozaril
    Dosage: 375 mg, unk
    Administration route: Oral
    Start date: 2012-03-01
    End date: 2012-03-12

Clozaril
    Dosage: 350 mg, qd
    Administration route: Oral
    Start date: 2004-08-11
    End date: 2007-07-01

Clozaril
    Dosage: 275 mg, unk
    Administration route: Oral
    Start date: 2012-02-12

Clozaril
    Dosage: 300 mg, unk
    Administration route: Oral

Other drugs received by patient: Omeprazole; Venlafaxine HCL; Quetiapine; Olanzapine; Seroquel; Diazepam; Nitrazepam; Clozapine; Multi-Vitamin; Effexor; Seroquel; Nitrazepam



Possible Clozaril side effects in male

Reported by a physician from Australia on 2012-08-22

Patient: male

Reactions: Mental Impairment, Psychotic Disorder, Anaemia, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 50 mg, unk
    Indication: Schizophrenia
    Start date: 1999-11-10
    End date: 2012-03-20

Clozaril
    Dosage: unk
    Start date: 2012-03-29

Clozaril
    Dosage: unk
    Start date: 2012-08-16

Valproate Sodium
    Start date: 2010-01-01
    End date: 2012-03-20



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-22

Patient: male, weighing 73.0 kg (160.6 pounds)

Reactions: White Blood Cell Count Decreased, Mental Impairment, Neutrophil Count Decreased

Drug(s) suspected as cause:
Clozaril
    Dosage: unk ukn, unk

Clozaril
    Dosage: unk ukn, unk
    Administration route: Oral
    Start date: 2012-01-10

Other drugs received by patient: Atenolol; Quetiapine; Omeprazole; Lactulose; Ferrous Sulfate TAB; Hyoscine Hydrobromide



Possible Clozaril side effects in male

Reported by a physician from NEW Zealand on 2012-08-17

Patient: male

Reactions: Mental Impairment, Consciousness Fluctuating, Hypophagia, Pulse Pressure Decreased, Depressed Level of Consciousness, Arrhythmia

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Aspirin; Docusate Sodium W / Senna; Cranberry Capsules; Calcium Carbonate; Furosemide; Colecalciferol; Alendronate Sodium



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-16

Patient: male

Reactions: Mental Impairment

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in female

Reported by a physician from Australia on 2012-08-14

Patient: female

Reactions: Mental Impairment, Psychotic Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Lithium Carbonate; Lithium Carbonate



Possible Clozaril side effects in female

Reported by a pharmacist from Australia on 2012-08-09

Patient: female

Reactions: Mental Impairment

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Clozaril
    Dosage: 350 mg, unk
    Start date: 1998-05-05



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-08-08

Patient: male, weighing 73.0 kg (160.6 pounds)

Reactions: White Blood Cell Count Decreased, Mental Impairment, Neutrophil Count Decreased

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Lactulose; Ferrous Sulfate TAB; Atenolol; Quetiapine; Omeprazole; Hyoscine Hydrobromide



Possible Clozaril side effects in male

Reported by a physician from Australia on 2012-08-08

Patient: male, weighing 109.0 kg (239.8 pounds)

Reactions: Blood Creatine Phosphokinase Increased, Head Injury, Hallucination, Auditory, Pyrexia, Feeling Cold, Myalgia, C-Reactive Protein Increased, Myoglobin Blood Increased, Injury, Myocarditis, Decreased Appetite, White Blood Cell Count Increased, Chest Discomfort, Dyspnoea, Nausea, Troponin T Increased, Tremor, Aggression, Mental Impairment, Affective Disorder, Heart Rate Increased, Troponin I Increased, Suicide Attempt, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 350 mg, qd
    Administration route: Oral
    End date: 2007-07-01

Clozaril
    Dosage: 375 mg, unk
    End date: 2012-03-12

Clozaril
    Dosage: 325 mg
    Administration route: Oral
    Start date: 2004-08-10

Clozaril
    Dosage: 275 mg, unk
    Administration route: Oral
    Start date: 2012-02-12

Clozaril
    Dosage: 300 mg, unk
    Administration route: Oral

Other drugs received by patient: Seroquel; Multi-Vitamin; Effexor; Seroquel; Clozapine; Olanzapine; Venlafaxine; Omeprazole; Quetiapine; Nitrazepam; Diazepam; Nitrazepam



Possible Clozaril side effects in male

Reported by a pharmacist from Australia on 2012-08-08

Patient: male

Reactions: Mental Impairment

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a pharmacist from United Kingdom on 2012-08-08

Patient: male

Reactions: Mental Impairment, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a pharmacist from United Kingdom on 2012-07-26

Patient: male

Reactions: Mental Impairment, Neutrophil Count Increased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a physician from Australia on 2012-07-23

Patient: male

Reactions: Weight Decreased, Mental Impairment, Obsessive-Compulsive Disorder, Depressive Symptom, Drug Ineffective, General Physical Health Deterioration, Hallucination

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 400 mg
    Administration route: Oral
    Start date: 1998-10-07

Clozaril
    Dosage: 100 mg, daily
    Start date: 1998-11-30

Clozaril
    Dosage: 400 mg, daily
    Start date: 1998-12-14

Clozaril
    Dosage: 600 mg, daily
    Start date: 1999-10-25

Clozaril
    Dosage: 400 mg, daily
    Start date: 1998-10-21

Clozaril
    Dosage: 200 mg, daily
    Start date: 1998-10-14

Clozaril
    Dosage: 300 mg, daily
    Start date: 1998-10-28

Clozaril
    Dosage: 300 mg, daily
    Start date: 2003-01-21



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-20

Patient: male

Reactions: White Blood Cell Count Decreased, Mental Impairment, Neutrophil Count Decreased

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Quetiapine



Possible Clozaril side effects in male

Reported by a physician from NEW Zealand on 2012-07-19

Patient: male

Reactions: Death, Mental Impairment, Consciousness Fluctuating, Hypophagia, Pulse Pressure Decreased, Depressed Level of Consciousness, Arrhythmia

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in female

Reported by a physician from United Kingdom on 2012-07-16

Patient: female

Reactions: Mental Impairment

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in male

Reported by a physician from United Kingdom on 2012-07-12

Patient: male

Reactions: Mental Impairment, Oedema Peripheral, Psoriasis, Blood Test Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril

Clozaril
    Indication: Schizophrenia
    Start date: 2004-12-17
    End date: 2006-12-01

Other drugs received by patient: Zuclopenthixol; Depot; Risperidone



Possible Clozaril side effects in 48 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-11

Patient: 48 year old male

Reactions: Mental Impairment, Eosinophil Count Decreased, Psychotic Disorder, Hepatitis C Virus Test Positive, Neutropenia, Salivary Hypersecretion, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 350 mg, unknown
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-02-20

Clozaril
    Dosage: 350 mg, unknown
    Administration route: Oral
    Start date: 2010-11-10
    End date: 2012-01-19

Pirenzepine
    Dosage: 50 mg, tid
    Administration route: Oral
    Indication: Salivary Hypersecretion
    Start date: 2010-06-08
    End date: 2012-01-20

Risperidone
    Dosage: 1 mg, bid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-06-08
    End date: 2012-01-27

Other drugs received by patient: Valproic Acid; Citalopram Hydrobromide; Olanzapine; Simvastatin



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-11

Patient: male

Reactions: Mental Impairment

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-10

Patient: female, weighing 55.0 kg (121.0 pounds)

Reactions: Mental Impairment, Agitation, White Blood Cell Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: 500 mg/day
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2001-11-19
    End date: 2011-06-01

Clozaril
    Dosage: unk ukn, unk
    Administration route: Oral
    Start date: 2012-04-27
    End date: 2012-06-20

Other drugs received by patient: Diazepam; Lithium Carbonate; Citalopram Hydrobromide; Antipsychotics



Possible Clozaril side effects in female

Reported by a physician from United Kingdom on 2012-07-09

Patient: female, weighing 76.0 kg (167.2 pounds)

Reactions: Enterococcal Infection, Anaemia, Device Related Infection, Weight Increased, Klebsiella Infection, Mental Impairment, Staphylococcal Infection, Oral Candidiasis, Hypophagia, Neutropenia, Escherichia Infection, Candidiasis, Klebsiella Sepsis, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril

Other drugs received by patient: Metformin HCL; Gabapentin; Levemir; Enoxaparin; Aripiprazole; Atenolol; Duloxetime Hydrochloride



Possible Clozaril side effects in male

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-06

Patient: male

Reactions: Mental Impairment, Treatment Noncompliance

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril



Possible Clozaril side effects in 48 year old male

Reported by a physician from United Kingdom on 2012-07-06

Patient: 48 year old male

Reactions: Mental Impairment, Eosinophil Count Decreased, Psychotic Disorder, Hepatitis C Virus Test Positive, Salivary Hypersecretion, Neutropenia, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-02-20

Clozaril
    Administration route: Oral
    Start date: 2010-11-10
    End date: 2012-01-19

Pirenzepine
    Administration route: Oral
    Indication: Salivary Hypersecretion
    Start date: 2010-06-08
    End date: 2012-01-20

Risperidone
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-06-08
    End date: 2012-01-27

Other drugs received by patient: Citalopram Hydrobromide; Olanzapine; Valproic Acid; Simvastatin



Possible Clozaril side effects in 48 year old male

Reported by a pharmacist from United Kingdom on 2012-07-06

Patient: 48 year old male

Reactions: Mental Impairment, White Blood Cell Count Decreased, Eosinophil Count Decreased, Psychotic Disorder, Hepatitis C Virus Test Positive, Neutropenia, Salivary Hypersecretion, Thrombocytopenia, Self-Injurious Ideation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: (350 mg), oral
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-02-20

Clozaril
    Dosage: (350 mg), oral
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-11-10
    End date: 2012-01-19

Pirenzepine (Pirenzepine)
    Dosage: 150 mg (50 mg,3 in 1 d), oral
    Administration route: Oral
    Indication: Salivary Hypersecretion
    Start date: 2010-06-08
    End date: 2012-01-20

Risperidone
    Dosage: 2 mg (1 mg, 2 in 1 d), oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-06-08
    End date: 2012-01-27

Other drugs received by patient: Olanzapine; Procyclidine Hydrochloride 2MG TAB; Simvastatin; Valproic Acid; Citalopram



Possible Clozaril side effects in 48 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-06

Patient: 48 year old male

Reactions: Eosinophil Count Decreased, Mental Impairment, Psychotic Disorder, Hepatitis C Virus Test Positive, Salivary Hypersecretion, Neutropenia, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-02-20

Clozaril
    Dosage: 100 mg morning and 250 mg ncte
    Administration route: Oral
    Start date: 2010-11-10
    End date: 2012-01-18

Pirenzepine
    Dosage: 50 mg, tid
    Administration route: Oral
    Indication: Salivary Hypersecretion
    Start date: 2010-06-08
    End date: 2012-01-20

Risperidone
    Dosage: 1 mg, bid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-06-08
    End date: 2012-01-27

Other drugs received by patient: Olanzapine; Valproic Acid; Simvastatin; Citalopram Hydrobromide



Possible Clozaril side effects in 48 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-05

Patient: 48 year old male

Reactions: Eosinophil Count Decreased, Hepatitis, Mental Impairment, Psychotic Disorder, Hepatitis C Virus Test Positive, Platelet Count Decreased, Neutropenia, Salivary Hypersecretion, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clozaril
    Dosage: unk
    Administration route: Oral
    Start date: 2010-11-10
    End date: 2012-01-19

Clozaril
    Dosage: unk
    Administration route: Oral
    Start date: 2010-11-10
    End date: 2012-01-18

Clozaril
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-02-20

Olanzapine
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-01-27

Pirenzepine
    Dosage: 50 mg, tid
    Administration route: Oral
    Indication: Salivary Hypersecretion
    Start date: 2010-06-08
    End date: 2012-01-20

Risperidone
    Dosage: 1 mg, bid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-06-08
    End date: 2012-01-27

Valproic Acid
    Dosage: 250 mg, tid
    Administration route: Oral
    Indication: Affective Disorder
    Start date: 2010-06-08

Other drugs received by patient: Procyclidine Hydrochloride 2MG TAB; Citalopram Hydrobromide; Citalopram Hydrobromide; Simvastatin; Olanzapine



Possible Clozaril side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-03

Patient: female

Reactions: Mental Impairment, Self-Injurious Ideation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozaril



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