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Clozapine (Clozapine) - White Blood Cell Count Decreased - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with White Blood Cell Count Decreased (116)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clozapine where reactions include white blood cell count decreased. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 116   Next >>

Possible Clozapine side effects in

Reported by a pharmacist from Spain on 2012-07-23

Patient:

Reactions: White Blood Cell Count Decreased, Agranulocytosis, Cytomegalovirus Infection, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Clonazepam; Quetiapine; Lithium Carbonate; Lactulose; Lormetazepam



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-16

Patient: male

Reactions: White Blood Cell Count Decreased, Neutrophil Count Increased, Drug Ineffective, Spinal Cord Injury, Mean Platelet Volume Increased, RED Cell Distribution Width Increased, Haemoglobin Decreased, Psychotic Disorder, Haematocrit Decreased, RED Blood Cell Count Decreased, Neutrophil Count Decreased, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Start date: 2008-01-01
    End date: 2011-09-22

Clozaril
    Dosage: 12.5 mg
    Start date: 2003-01-31
    End date: 2007-04-03



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-13

Patient: female

Reactions: White Blood Cell Count Decreased, B-Cell Lymphoma, Paranoia, Lymphopenia, Burkitt's Lymphoma, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 400 mg, qd

Clozaril
    Dosage: 800 mg, unk
    Start date: 2007-08-21
    End date: 2009-11-02

Clozaril
    Dosage: 750 mg, unk
    Start date: 2009-11-30
    End date: 2010-06-28

Clozaril
    Dosage: 300 mg, unk
    Start date: 2011-07-19
    End date: 2011-07-25

Clozaril
    Dosage: 750 mg, unk
    Start date: 2007-02-06
    End date: 2007-07-27

Clozaril
    Dosage: 200 mg, unk
    Start date: 2011-07-04
    End date: 2011-07-18

Clozaril
    Dosage: 450 mg, daily
    Start date: 2005-02-23

Clozaril
    Dosage: 650 mg, unk
    Start date: 2010-10-18
    End date: 2011-05-30

Clozaril
    Dosage: 400 mg, unk
    Start date: 2011-08-01
    End date: 2011-09-05

Clozaril
    Dosage: 500 mg, unk
    Start date: 2011-09-20
    End date: 2011-11-23

Clozaril
    Dosage: 475 mg, unk
    Start date: 2011-12-15
    End date: 2012-02-17

Clozaril
    Dosage: 450 mg, unk
    Start date: 2012-02-20

Clozaril
    Start date: 2004-02-04

Clozaril
    Dosage: 700 mg, unk
    Start date: 2010-07-27
    End date: 2010-09-21



Possible Clozapine side effects in 80 year old male

Reported by a physician from Finland on 2012-07-12

Patient: 80 year old male

Reactions: White Blood Cell Count Decreased, Dyspnoea, General Physical Condition Abnormal, Pneumonia, Hypotension, Rhinitis, Headache, C-Reactive Protein Increased, Chest Pain, Dizziness, Hypertension, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 125 mg, unk
    Start date: 2012-01-23
    End date: 2012-03-06

Clozapine
    Dosage: 75 mg/day
    Start date: 2011-08-08

Clozapine
    Dosage: 150 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-06-27

Clozapine
    Start date: 2012-06-26



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-11

Patient: female

Reactions: White Blood Cell Count Decreased, Paranoia, Burkitt's Lymphoma, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 400 mg, qd

Clozaril
    Dosage: 750 mg, unk
    Start date: 2007-02-06
    End date: 2007-07-27

Clozaril
    Dosage: 750 mg, unk
    Start date: 2009-11-30
    End date: 2010-06-28

Clozaril
    Dosage: 450 mg, unk
    Start date: 2012-02-20

Clozaril
    Start date: 2004-02-04

Clozaril
    Dosage: 650 mg, unk
    Start date: 2010-10-18
    End date: 2011-05-30

Clozaril
    Dosage: 400 mg, unk
    Start date: 2011-08-01
    End date: 2011-09-05

Clozaril
    Dosage: 500 mg, unk
    Start date: 2011-09-20
    End date: 2011-11-23

Clozaril
    Dosage: 475 mg, unk
    Start date: 2011-12-15
    End date: 2012-02-17

Clozaril
    Dosage: 800 mg, unk
    Start date: 2007-08-21
    End date: 2009-11-02

Clozaril
    Dosage: 200 mg, unk
    Start date: 2011-07-04
    End date: 2011-07-18

Clozaril
    Dosage: 450 mg, daily
    Start date: 2005-02-23

Clozaril
    Dosage: 700 mg, unk
    Start date: 2010-07-27
    End date: 2010-09-21

Clozaril
    Dosage: 300 mg, unk
    Start date: 2011-07-19
    End date: 2011-07-25



Possible Clozapine side effects in 80 year old male

Reported by a physician from Finland on 2012-07-11

Patient: 80 year old male

Reactions: White Blood Cell Count Decreased, General Physical Condition Abnormal, Dyspnoea, Pneumonia, Hypotension, Rhinitis, Headache, C-Reactive Protein Increased, Chest Pain, Dizziness, Hypertension, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 125 mg, unk
    Start date: 2012-01-23
    End date: 2012-03-06

Clozapine
    Start date: 2012-06-26

Clozapine
    Dosage: 75 mg/day
    Start date: 2011-08-08

Clozapine
    Dosage: 150 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-06-27



Possible Clozapine side effects in 45 year old female

Reported by a health professional (non-physician/pharmacist) from India on 2012-07-05

Patient: 45 year old female

Reactions: White Blood Cell Count Decreased, Agranulocytosis, Body Temperature Increased, Platelet Count Decreased, Oropharyngeal Pain, Neutrophil Count Decreased

Drug(s) suspected as cause:
Clozapine
    Dosage: 25 mg, daily
    Administration route: Oral
    Indication: Schizophrenia

Clozapine
    Dosage: 400 mg, daily
    Administration route: Oral



Possible Clozapine side effects in 80 year old male

Reported by a physician from Finland on 2012-07-04

Patient: 80 year old male

Reactions: White Blood Cell Count Decreased, Pneumonia, General Physical Condition Abnormal, Dyspnoea, Hypotension, Rhinitis, Headache, C-Reactive Protein Increased, Chest Pain, Dizziness, Neutrophil Count Decreased, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Start date: 2012-06-26

Clozapine
    Dosage: 75 mg/day
    Start date: 2011-08-08

Clozapine
    Dosage: 150 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-06-27

Clozapine
    Dosage: 125 mg, unk
    Start date: 2012-01-23
    End date: 2012-03-06



Possible Clozapine side effects in 48 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 48 year old female, weighing 90.7 kg (199.6 pounds)

Reactions: White Blood Cell Count Decreased, Granulocytopenia

Drug(s) suspected as cause:
Clozapine

Clozapine
    Administration route: Oral
    Start date: 2011-02-01
    End date: 2011-02-01

Clozapine
    Administration route: Oral
    Start date: 2009-07-29
    End date: 2011-02-01

Other drugs received by patient: Abilify; Divalproex Sodium; Lexapro; Aspirin; Polyethylene Glycol; Benztropine Mesylate; Topamax; Ranitidine; Metformin HCL; Buspirone HCL; M.v.i.



Possible Clozapine side effects in 26 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 26 year old male, weighing 99.8 kg (219.5 pounds)

Reactions: White Blood Cell Count Decreased, Granulocytopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Start date: 2010-07-01
    End date: 2011-05-25

Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-07-01
    End date: 2011-05-25

Other drugs received by patient: Ativan; Artane; Prozac; Trileptal; Trileptal



Possible Clozapine side effects in 46 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 46 year old female, weighing 83.9 kg (184.6 pounds)

Reactions: White Blood Cell Count Decreased, Granulocytopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Schizoaffective Disorder
    Start date: 2011-08-15
    End date: 2011-08-27

Clozapine
    Administration route: Oral
    Start date: 2011-08-27
    End date: 2011-09-14

Other drugs received by patient: Aspirin; Synthroid; Metformin HCL; Exelon; Geodon; Lamictal



Possible Clozapine side effects in 42 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 42 year old female

Reactions: White Blood Cell Count Decreased, Granulocytopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Bipolar Disorder
    Start date: 2011-01-24
    End date: 2011-02-01

Clozapine
    Administration route: Oral
    Start date: 2011-02-02
    End date: 2011-02-04

Clozapine
    Administration route: Oral
    Start date: 2011-02-02
    End date: 2011-02-04

Other drugs received by patient: Depakote; Seroquel XR; Topamax; Thiamine; Levothyroxine; Zoloft; Multi-Vitamin



Possible Clozapine side effects in female

Reported by a physician from Australia on 2012-06-28

Patient: female

Reactions: White Blood Cell Count Decreased, Paranoia, Burkitt's Lymphoma, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 400 mg, qd

Clozaril
    Dosage: 200 mg, unk
    Start date: 2011-07-04
    End date: 2011-07-18

Clozaril
    Dosage: 400 mg, unk
    Start date: 2011-08-01
    End date: 2011-09-05

Clozaril
    Dosage: 500 mg, unk
    Start date: 2011-09-20
    End date: 2011-11-23

Clozaril
    Dosage: 700 mg, unk
    Start date: 2010-07-27
    End date: 2010-09-21

Clozaril
    Dosage: 750 mg, unk
    Start date: 2007-02-06
    End date: 2007-07-27

Clozaril
    Dosage: 650 mg, unk
    Start date: 2010-10-18
    End date: 2011-05-30

Clozaril
    Start date: 2004-02-04

Clozaril
    Dosage: 475 mg, unk
    Start date: 2011-12-15
    End date: 2012-02-17

Clozaril
    Dosage: 450 mg, unk
    Start date: 2012-02-20

Clozaril
    Dosage: 800 mg, unk
    Start date: 2007-08-21
    End date: 2009-11-02

Clozaril
    Dosage: 750 mg, unk
    Start date: 2009-11-30
    End date: 2010-06-28

Clozaril
    Dosage: 450 mg, daily
    Start date: 2005-02-23

Clozaril
    Dosage: 300 mg, unk
    Start date: 2011-07-19
    End date: 2011-07-25



Possible Clozapine side effects in 21 year old male

Reported by a physician from United States on 2012-06-28

Patient: 21 year old male

Reactions: White Blood Cell Count Decreased, Agranulocytosis, Neutropenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in 68 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 68 year old female

Reactions: White Blood Cell Count Decreased, Granulocytopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-07-13
    End date: 2011-03-17

Clozapine
    Administration route: Oral
    Start date: 2010-07-13
    End date: 2011-03-17



Possible Clozapine side effects in 29 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 29 year old female, weighing 78.0 kg (171.6 pounds)

Reactions: White Blood Cell Count Decreased, Granulocytopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2009-12-14
    End date: 2011-11-11

Clozapine
    Administration route: Oral
    Start date: 2009-12-14
    End date: 2011-11-11

Other drugs received by patient: Oral Contraceptive NOS



Possible Clozapine side effects in 43 year old male

Reported by a physician on 2012-06-28

Patient: 43 year old male

Reactions: Back Pain, White Blood Cell Count Decreased, Drug Interaction, Neutropenia

Drug(s) suspected as cause:
Acetaminophen W / Codeine
    Indication: Back Pain

Clozapine
    Dosage: (650 mg,1 d),oral ; oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-02

Clozapine
    Dosage: (650 mg,1 d),oral ; oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-07-01
    End date: 2012-04-25

Ibuprofen
    Indication: Back Pain

Lamotrigine
    Dosage: 200 mg (200 mg,1 in 1 d)
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Sulprid (Sulpiride)



Possible Clozapine side effects in 42 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 42 year old male

Reactions: White Blood Cell Count Decreased, Granulocytopenia

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Amphetamine and Dextroamphetamine Salts; Lantus; Oxycodone / Acetaminophen



Possible Clozapine side effects in 42 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 42 year old male

Reactions: White Blood Cell Count Decreased, Granulocytopenia

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Wellbutrin; Clonazepam; Abilify; Clindamycin; Fentanyl-100



Possible Clozapine side effects in 43 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 43 year old male

Reactions: White Blood Cell Count Decreased, Granulocytopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Start date: 2011-11-01
    End date: 2012-01-01

Clozapine
    Administration route: Oral
    Start date: 1999-01-01
    End date: 2011-11-01



Possible Clozapine side effects in male

Reported by a consumer/non-health professional from Canada on 2012-06-27

Patient: male

Reactions: Agitation, Pco2 Decreased, Blood Calcium Decreased, Poor Quality Sleep, Speech Disorder, Mania, Haematocrit Decreased, RED Blood Cell Count Decreased, Blood Sodium Increased, Blood Bicarbonate Increased, Blood Creatinine Increased, Lymphocyte Count Decreased, White Blood Cell Count Decreased, Urine Albumin / Creatinine Ratio Increased, Blood Urea Increased, Glomerular Filtration Rate Decreased, Urinary Tract Infection, Haemoglobin Decreased, Hallucination, Visual, Platelet Count Decreased, Base Excess Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Allopurinol; Valproate Sodium; Pantoprazole Sodium; Colace; Calcium Carbonate; Rocaltrol; Carvedilol; Sodium Bicarbonate



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-06-22

Patient: female, weighing 100.0 kg (220.0 pounds)

Reactions: White Blood Cell Count Decreased, Neutrophil Count Increased, Neoplasm Malignant, Ear Infection, Neutropenia, Neutrophil Count Decreased, Lymphoma, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 200 mg, unk
    Start date: 1997-10-03

Clozaril
    Dosage: 200 mg, unk
    Administration route: Oral
    Start date: 1997-10-03

Clozaril
    Dosage: 250 mg, unk
    Start date: 2012-05-08

Clozaril
    Dosage: 200 mg, unk

Other drugs received by patient: Chlorhexidine Gluconate; Fludrocortisone Acetate; Ranitidine; Potassium Chloride; Valproate Sodium; Senna-Mint WAF; Magnesium Aspartate; Pravastatin; Nystatin; Gliclazide; Sulfamethoxazole and Trimethoprim; Valaciclovir; Docusate



Possible Clozapine side effects in 43 year old male

Reported by a physician from United Kingdom on 2012-06-22

Patient: 43 year old male

Reactions: White Blood Cell Count Decreased, Back Pain, Drug Interaction, Neutropenia, Neutrophil Count Decreased

Drug(s) suspected as cause:
Acetaminophen and Codeine Phosphate
    Indication: Back Pain

Clozapine
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-02

Clozapine
    Administration route: Oral
    Start date: 2005-07-01
    End date: 2012-04-25

Other drugs received by patient possibly interacting with the suspect drug:
Ibuprofen
    Indication: Back Pain

Lamotrigine
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Sulpiride



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-06-22

Patient: female, weighing 100.0 kg (220.0 pounds)

Reactions: White Blood Cell Count Decreased, Neutrophil Count Increased, Neoplasm Malignant, Ear Infection, Neutropenia, Neutrophil Count Decreased, Lymphoma, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 200 mg, unk
    Start date: 1997-10-03

Clozaril
    Dosage: 200 mg, unk
    Administration route: Oral
    Start date: 1997-10-03

Clozaril
    Dosage: 200 mg, unk

Clozaril
    Dosage: 250 mg, unk
    Start date: 2012-05-08

Other drugs received by patient: Sulfamethoxazole and Trimethoprim; Ranitidine; Valaciclovir; Fludrocortisone Acetate; Senna-Mint WAF; Docusate; Pravastatin; Chlorhexidine Gluconate; Gliclazide; Potassium Chloride; Nystatin; Valproate Sodium; Magnesium Aspartate



Possible Clozapine side effects in 43 year old male

Reported by a physician from United Kingdom on 2012-06-21

Patient: 43 year old male

Reactions: White Blood Cell Count Decreased, Back Pain, Drug Interaction, Neutropenia, Neutrophil Count Decreased

Drug(s) suspected as cause:
Acetaminophen and Codeine Phosphate
    Dosage: unk
    Indication: Back Pain

Clozapine
    Dosage: 650 mg, 1x/day
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-07-01
    End date: 2012-04-25

Clozapine
    Dosage: unk
    Administration route: Oral
    Start date: 2012-05-02

Other drugs received by patient possibly interacting with the suspect drug:
Ibuprofen
    Dosage: unk
    Indication: Back Pain

Lamotrigine
    Dosage: 200 mg, 1x/day

Other drugs received by patient: Sulpiride



Possible Clozapine side effects in female

Reported by a physician from Finland on 2012-06-20

Patient: female

Reactions: White Blood Cell Count Decreased, Agranulocytosis, Neutropenia, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in male

Reported by a consumer/non-health professional from Venezuela on 2012-06-17

Patient: male

Reactions: White Blood Cell Count Decreased, Monocyte Count Decreased, Neutrophil Count Decreased

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in male

Reported by a consumer/non-health professional from Venezuela on 2012-06-15

Patient: male

Reactions: Lymphocyte Count Increased, White Blood Cell Count Decreased, Monocyte Percentage Decreased, Neutrophil Count Decreased

Drug(s) suspected as cause:
Clozapine
    Dosage: 50 mg, unk
    Administration route: Oral

Clozapine
    Dosage: 100 mg, unk
    Administration route: Oral

Clozapine
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-04-26

Clozapine
    Dosage: 200 mg, unk
    Start date: 2006-06-01



Possible Clozapine side effects in 33 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-12

Patient: 33 year old male

Reactions: White Blood Cell Count Decreased, Dyspepsia, Drug Interaction, Neutropenia, Depression, Hypertension, Constipation

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg;po
    Administration route: Oral
    Start date: 2012-03-19
    End date: 2012-04-01

Clozapine
    Dosage: 100 mg;po
    Administration route: Oral
    Start date: 2011-10-25
    End date: 2012-03-07

Ramipril
    Dosage: 2.5 mg;qd 5 mg;qd 10 mg;qd
    Indication: Hypertension
    Start date: 2012-03-06
    End date: 2012-03-09

Ramipril
    Dosage: 2.5 mg;qd 5 mg;qd 10 mg;qd
    Indication: Hypertension
    Start date: 2011-08-22

Ramipril
    Dosage: 2.5 mg;qd 5 mg;qd 10 mg;qd
    Indication: Hypertension
    Start date: 2012-03-02

Ribavirin
    Dosage: 1200 mg;po
    Administration route: Oral
    Indication: Hepatitis C
    Start date: 2011-05-16

Other drugs received by patient: Beclomethasone Dipropionate; Calcichew D3 (Lekovit CA); Moviprep; Clozapine; Omeprazole; Peginterferon Alfa-2A; Venlafaxine HCL



Possible Clozapine side effects in 33 year old male

Reported by a physician from United Kingdom on 2012-06-08

Patient: 33 year old male

Reactions: White Blood Cell Count Decreased, Drug Interaction, Neutropenia, Neutrophil Count Decreased

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg, 2x/day
    Administration route: Oral
    Start date: 2012-03-19
    End date: 2012-04-01

Clozapine
    Dosage: 50 mg in the morning and 300 in the night
    Administration route: Oral
    Start date: 2011-10-25
    End date: 2012-03-07

Peginterferon Alfa-2A
    Dosage: 180 ug, weekly
    Indication: Hepatitis C
    Start date: 2011-05-16

Other drugs received by patient possibly interacting with the suspect drug:
Ramipril
    Dosage: 10 mg, 1x/day
    Start date: 2012-03-06
    End date: 2012-05-09

Ramipril
    Dosage: 5 mg, 1x/day
    Start date: 2012-03-02

Ramipril
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2011-08-22

Ribavirin
    Dosage: 1200 mg, unk
    Administration route: Oral
    Indication: Hepatitis C
    Start date: 2011-05-16

Other drugs received by patient: Calcichew-D3; Moviprep; Beclomethasone Dipropionate; Venlafaxine; Omeprazole



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