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Clozapine (Clozapine) - Leukopenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Leukopenia (231)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clozapine where reactions include leukopenia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 231   Next >>

Possible Clozapine side effects in

Reported by a physician from Germany on 2012-08-21

Patient:

Reactions: Hypothermia, Dementia, Drug Interaction, Catatonia, Miosis, Liver Function Test Abnormal, Pupil Fixed, Leukopenia, Oxygen Saturation Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg, / day
    Indication: Schizophrenia, Catatonic Type

Haloperidol
    Dosage: 5 mg, / day
    Indication: Schizophrenia, Catatonic Type

Haloperidol
    Dosage: 2 mg, / day

Haloperidol Decanoate
    Dosage: 100 mg, every 4 weeks
    Indication: Schizophrenia, Catatonic Type

Other drugs received by patient possibly interacting with the suspect drug:
Lorazepam
    Dosage: 3 to 4.5 mg per day,divided into three single doses
    Administration route: Oral
    Indication: Schizophrenia, Catatonic Type

Lorazepam
    Dosage: 1-1-1 mg
    Administration route: Oral

Olanzapine
    Dosage: 10 mg, / day
    Indication: Schizophrenia, Catatonic Type

Olanzapine
    Dosage: 10 mg, single
    Administration route: Oral



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-08-16

Patient: female, weighing 75.0 kg (165.0 pounds)

Reactions: Renal Disorder, Agranulocytosis, Hypophagia, Somnolence, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Aspirin; Persantine; Exelon; Nexium; Carbidopa + Levodopa; Movicolon; Triamteren; Amoxicillin and Clavulanate Potassium; Trimethoprim; Arimidex; Acetaminophen; Seroquel; Calcium Carbonate W / Colecalciferol



Possible Clozapine side effects in 60 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-02

Patient: 60 year old female

Reactions: Urinary Tract Infection, Depression, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 25 mg, daily
    Indication: Psychotic Disorder
    Start date: 2011-12-28
    End date: 2012-05-30

Clozapine
    Dosage: 12.5 mg, daily
    Start date: 2012-06-13
    End date: 2012-06-18

Clozapine
    Dosage: 50 mg, daily
    Start date: 2012-01-01

Mianserine G GAM
    Dosage: 10 mg, unk
    Administration route: Oral
    Indication: Depression
    Start date: 2012-05-25
    End date: 2012-05-31

Other drugs received by patient: Lithium Carbonate; Calcium Carbonate; Modopar; Azilect; Sinemet; Oxybutynin; Stalevo 100; Mirtazapine; Rivotril; Atarax; Acid Alendronique



Possible Clozapine side effects in 49 year old male

Reported by a pharmacist from United Kingdom on 2012-08-02

Patient: 49 year old male

Reactions: Drug Interaction, Neutrophil Count Decreased, Tonsil Cancer, Leukopenia

Drug(s) suspected as cause:
Cisplatin
    Dosage: unk
    Indication: Tonsil Cancer
    Start date: 2010-09-01
    End date: 2010-10-01

Clozapine
    Dosage: unk
    Administration route: Oral
    Start date: 2010-06-24



Possible Clozapine side effects in 60 year old female

Reported by a pharmacist from France on 2012-07-30

Patient: 60 year old female

Reactions: Urinary Tract Infection, Depression, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 50 mg, daily
    Start date: 2012-01-01

Clozapine
    Dosage: 12.5 mg, daily
    Start date: 2012-06-13
    End date: 2012-06-18

Clozapine
    Dosage: 25 mg, daily
    Indication: Psychotic Disorder
    Start date: 2011-12-28
    End date: 2012-05-30

Mianserine G GAM
    Dosage: 10 mg, unk
    Administration route: Oral
    Indication: Depression
    Start date: 2012-05-25
    End date: 2012-05-31

Other drugs received by patient: Atarax; Acid Alendronique; Lithium Carbonate; Sinemet; Oxybutynin; Modopar; Calcium Carbonate; Mirtazapine; Azilect; Stalevo 100; Clonazepam



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-07-25

Patient: female, weighing 75.0 kg (165.0 pounds)

Reactions: Renal Disorder, Agranulocytosis, Hypophagia, Somnolence, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Exelon



Possible Clozapine side effects in 35 year old male

Reported by a consumer/non-health professional from Finland on 2012-07-25

Patient: 35 year old male

Reactions: Neutropenia, Idiopathic Thrombocytopenic Purpura, Thrombocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 600 mg, per day
    Start date: 2007-01-01

Clozapine
    Dosage: 600 mg, per day
    Indication: Schizophrenia

Other drugs received by patient: Bisoprolol Fumarate; Lorazepam



Possible Clozapine side effects in 51 year old female

Reported by a health professional (non-physician/pharmacist) from Switzerland on 2012-07-23

Patient: 51 year old female, weighing 56.0 kg (123.2 pounds)

Reactions: Confusional State, Acquired Tracheo-Oesophageal Fistula, Haemorrhage, Pyrexia, Subclavian Vein Thrombosis, Agranulocytosis, Escherichia Test Positive, Aspiration, Oesophagitis, Respiratory Failure, Urosepsis, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Bipolar Disorder
    Start date: 2012-02-01
    End date: 2012-04-29

Seroquel
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2012-02-01
    End date: 2012-04-29

Other drugs received by patient: Calcimagon-D3; Lorazepam; Levothyroxine Sodium; Lithium Carbonate; Ezetimibe



Possible Clozapine side effects in female

Reported by a physician from Germany on 2012-07-13

Patient: female, weighing 83.0 kg (182.6 pounds)

Reactions: Antipsychotic Drug Level Increased, Listless, Pneumonia, Leukopenia, RIB Fracture

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 300 mg, qd
    Indication: Schizophrenia, Paranoid Type
    Start date: 2004-01-01
    End date: 2011-12-28

Clozapine
    Dosage: 300 mg, qd
    Start date: 2012-01-04
    End date: 2012-01-01

Other drugs received by patient: Amisulpride; Sertraline Hydrochloride



Possible Clozapine side effects in female

Reported by a physician from Denmark on 2012-07-10

Patient: female, weighing 94.0 kg (206.8 pounds)

Reactions: Death, Schizophrenia, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Glucosamine; Escitalopram; Propranolol



Possible Clozapine side effects in 58 year old female

Reported by a pharmacist from United States on 2012-06-29

Patient: 58 year old female, weighing 65.9 kg (145.0 pounds)

Reactions: Gastrointestinal Haemorrhage, Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Senna S; Omeprazole; Loratadine; Multivitamin and Mineral; Vitamin D; Lortab; Lorazepam; Levothyroxine; Potassium Chloride; Aspirin; Lamotrigine; Furosemide; Carboxymethylcellulose Sodium



Possible Clozapine side effects in 60 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 60 year old female

Reactions: Granulocytopenia, Leukopenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Lutein / 01638501 /; Vitamin D; Depakote ER; Dextroamphetamine; Multi-Vitamin; Apap TAB; Synthroid; Evista; Trileptal; Restasis; Omega 3 / 01334101 /; Acetylcysteine; Dextroamphetamine; Dextroamphetamine; Vitamin E; Preservision EYE Vitamin and Mineral Suppl.



Possible Clozapine side effects in

Reported by a pharmacist from United States on 2012-06-28

Patient:

Reactions: Agranulocytosis, Granulocytopenia, Leukopenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in 36 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 36 year old female

Reactions: Agranulocytosis, Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Lorazepam; Bactrim; Benzac / 00088302 /; Lipitor; Detrol LA; Glycopyrrolate; Levothyroxine; Triamterene and Hydrochlorothiazide; Valtrex; Voltaren; Cytomel; Estradiol; Metformin HCL; Nasonex; Polyethylene Glycol; Dicyclomine; Nystatin; Pantoprazole; Tizanidine Hydrochloride; Albuterol Sulfate



Possible Clozapine side effects in 54 year old male

Reported by a physician from United States on 2012-06-28

Patient: 54 year old male

Reactions: Granulocytopenia, Myocardial Infarction, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Schizoaffective Disorder
    Start date: 2011-09-19
    End date: 2012-02-10

Clozapine
    Administration route: Oral
    Start date: 2011-09-19
    End date: 2012-02-10

Other drugs received by patient: Trazodone HCL; Klonopin; Wellbutrin XL; Celexa; Haldol



Possible Clozapine side effects in 28 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 28 year old male

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    End date: 2010-12-05

Clozapine
    Administration route: Oral
    End date: 2010-12-05



Possible Clozapine side effects in 50 year old male

Reported by a physician from United States on 2012-06-28

Patient: 50 year old male, weighing 106.1 kg (233.5 pounds)

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Start date: 2011-07-25

Clozapine
    Dosage: 100mg to 200mg tid
    End date: 2011-08-12

Clozapine
    Indication: Schizophrenia
    Start date: 2009-08-04
    End date: 2011-06-01

Clozapine
    Start date: 2011-06-01
    End date: 2011-07-12

Clozapine
    Start date: 2011-07-25

Clozapine
    Start date: 2011-06-01
    End date: 2011-07-12

Other drugs received by patient: Reglan; Wellbutrin; Zovirax; Pravastatin; Aciphex; Cymbalta; Kaletra; Exelon; Sotalol Hydrochloride; Namenda; Isentress; Coumadin



Possible Clozapine side effects in 19 year old male

Reported by a physician from United States on 2012-06-28

Patient: 19 year old male

Reactions: Agranulocytosis, Granulocytopenia, Leukopenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Lorazepam; Geodon; Gabapentin; Strattera; Risperdal Consta; Saphris



Possible Clozapine side effects in 50 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 50 year old female

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Indication: Schizophrenia
    End date: 2012-03-26

Clozapine
    Start date: 2012-03-27
    End date: 2012-03-28

Other drugs received by patient: Navane; Celexa; Trazodone HCL; Ativan



Possible Clozapine side effects in 43 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 43 year old male, weighing 67.1 kg (147.7 pounds)

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Psychotic Disorder
    End date: 2012-01-20

Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    End date: 2012-01-20

Other drugs received by patient: Alprazolam; Zyprexa; Chemotherapeutics



Possible Clozapine side effects in 40 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 40 year old female

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Start date: 2012-05-24

Clozapine
    Administration route: Oral
    End date: 2012-05-08

Other drugs received by patient: Synthroid



Possible Clozapine side effects in 60 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 60 year old male

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Start date: 2011-10-17

Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    End date: 2011-10-14

Clozapine
    Administration route: Oral
    Start date: 2011-10-17

Clozapine
    Administration route: Oral
    End date: 2011-10-14

Other drugs received by patient: Toprol-XL; Lopid; Actos; Glipizide; Pravachol; Lithium Carbonate; Metformin HCL



Possible Clozapine side effects in 45 year old female

Reported by a physician from United States on 2012-06-28

Patient: 45 year old female, weighing 68.0 kg (149.7 pounds)

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Indication: Schizophrenia, Paranoid Type
    End date: 2011-06-13

Clozapine
    End date: 2011-08-01

Clozapine
    End date: 2011-08-01

Clozapine
    Start date: 2011-08-01

Clozapine
    Start date: 2011-06-14
    End date: 2011-07-13

Other drugs received by patient: Docusate; Diazepam; Geodon; Namenda; Tricor; Vitamin E; Levothroid



Possible Clozapine side effects in 39 year old male

Reported by a physician from United States on 2012-06-28

Patient: 39 year old male

Reactions: Agranulocytosis, Leukopenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in 66 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 66 year old female, weighing 121.6 kg (267.4 pounds)

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in 47 year old female

Reported by a pharmacist from United States on 2012-06-28

Patient: 47 year old female

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Baclofen; Propranolol; Geodon; Lamictal



Possible Clozapine side effects in 59 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-28

Patient: 59 year old male, weighing 87.5 kg (192.5 pounds)

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 75mg in the morning and 100mg at bedtime
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    End date: 2012-03-14

Clozapine
    Dosage: 75mg in the morning and 100mg at bedtime
    Administration route: Oral
    Start date: 2012-03-15

Other drugs received by patient: Simvastatin; Olanzapine; Ferrous Sulfate TAB; Haloperidol; Benztropine Mesylate; Senna S; Levothyroxine; Clonazepam; Lorazepam; Depakote ER; Lansoprazole; Lisinopril



Possible Clozapine side effects in 60 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 60 year old male

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    End date: 2011-05-05

Clozapine
    Administration route: Oral
    Start date: 2011-05-01

Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    End date: 2011-05-05

Clozapine
    Administration route: Oral
    Start date: 2011-05-01

Other drugs received by patient: Metoprolol Tartrate; Metformin HCL; Lithium Carbonate; Lopid; Actos; Glipizide; Pravastatin



Possible Clozapine side effects in 25 year old male

Reported by a physician from United States on 2012-06-28

Patient: 25 year old male

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in 41 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-28

Patient: 41 year old male

Reactions: Granulocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Bipolar Disorder
    End date: 2011-10-03

Clozapine
    Administration route: Oral
    End date: 2011-10-03

Pegasys
    Indication: Hepatitis C
    Start date: 2011-07-01

Other drugs received by patient: Cymbalta; Zyprexa



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