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Clozapine (Clozapine) - Agitation - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Agitation ()

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clozapine where reactions include agitation. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of    Next >>

Possible Clozapine side effects in 42 year old male

Reported by a consumer/non-health professional from Brazil on 2012-07-27

Patient: 42 year old male

Reactions: Agitation, Psychotic Disorder, Vitello-Intestinal Duct Remnant, Appendicitis, Ileus Paralytic

Drug(s) suspected as cause:
Clozapine
    Dosage: 3 df, daily (1 tablet in the morning and 2 tablets at night)
    Indication: Schizophrenia
    Start date: 2002-01-01

Clozapine
    Dosage: 5 df, (2 tablets at morning and 3 tablets at night)



Possible Clozapine side effects in 48 year old female

Reported by a pharmacist from United States on 2012-07-18

Patient: 48 year old female

Reactions: Agitation, Blood Creatine Phosphokinase Increased, Hyperthermia, Hallucination, Auditory, Unresponsive To Stimuli, Muscle Rigidity, Haematemesis, Social Avoidant Behaviour, Blood Creatinine Increased, Blood Glucose Increased, Lethargy, Blood Urea Increased, Restlessness, Catatonia, Foreign Body, Dehydration, Upper Gastrointestinal Haemorrhage, Withdrawal Syndrome, Leukocytosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lamotrigine
    Dosage: 100 mg, bid, po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Haloperidol
    Dosage: 5 mg, iv
    Indication: Agitation

Paroxetine HCL
    Dosage: 40;20;30 mg, qd
    Indication: Product Used FOR Unknown Indication

Clozapine
    Indication: Agitation

Other drugs received by patient: Diphenhydramine HCL; Glimepiride; Diphenhydramine HCL; Famotidine; Pantoprazole



Possible Clozapine side effects in male

Reported by a consumer/non-health professional from United States on 2012-06-28

Patient: male, weighing 104.3 kg (229.5 pounds)

Reactions: Agitation, Coprolalia, Communication Disorder, Abnormal Behaviour

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Start date: 2004-12-04
    End date: 2005-02-01

Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2002-02-11
    End date: 2004-11-23



Possible Clozapine side effects in male

Reported by a consumer/non-health professional from Canada on 2012-06-27

Patient: male

Reactions: Agitation, Pco2 Decreased, Blood Calcium Decreased, Poor Quality Sleep, Speech Disorder, Mania, Haematocrit Decreased, RED Blood Cell Count Decreased, Blood Sodium Increased, Blood Bicarbonate Increased, Blood Creatinine Increased, Lymphocyte Count Decreased, White Blood Cell Count Decreased, Urine Albumin / Creatinine Ratio Increased, Blood Urea Increased, Glomerular Filtration Rate Decreased, Urinary Tract Infection, Haemoglobin Decreased, Hallucination, Visual, Platelet Count Decreased, Base Excess Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Allopurinol; Valproate Sodium; Pantoprazole Sodium; Colace; Calcium Carbonate; Rocaltrol; Carvedilol; Sodium Bicarbonate



Possible Clozapine side effects in 26 year old female

Reported by a physician from Belgium on 2012-06-27

Patient: 26 year old female

Reactions: Agitation, Confusional State, Poisoning

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-22

Patient: male

Reactions: Confusional State, Agitation, Aphasia, Pyrexia, Disorientation, Pallor, Fall, Electroencephalogram Abnormal, Speech Disorder, Malaise, C-Reactive Protein Increased, Crepitations, Heart Rate Irregular, White Blood Cell Count Increased, Prurigo, General Physical Health Deterioration, Abnormal Behaviour, Atrial Fibrillation, Rash, Computerised Tomogram Abnormal, Diastolic Hypotension, Insomnia, Mitral Valve Incompetence, Fibrin Increased, RED Blood Cell Sedimentation Rate Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Aspirin; Tercian; Exelon; Diclofenac Sodium



Possible Clozapine side effects in 26 year old female

Reported by a physician from Belgium on 2012-06-20

Patient: 26 year old female

Reactions: Confusional State, Agitation, Poisoning

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in 45 year old male

Reported by a consumer/non-health professional from United States on 2012-06-11

Patient: 45 year old male

Reactions: Agitation, Confusional State, Vomiting, Blood Creatine Phosphokinase Increased, Restlessness, Hallucination, Auditory, Tachycardia, Impulsive Behaviour, White Blood Cell Disorder, Neuroleptic Malignant Syndrome, Memory Impairment

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozapine
    Indication: Bipolar I Disorder
    Start date: 2007-01-01
    End date: 2011-08-01

Latuda
    Administration route: Oral
    Indication: Bipolar I Disorder
    Start date: 2012-05-10
    End date: 2012-05-13

Clozapine
    Start date: 2011-08-01
    End date: 2012-05-13

Other drugs received by patient: Depakote; Klor-CON; Ditropan; Lasix



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-04

Patient: male

Reactions: Confusional State, Agitation, Blood Creatine Phosphokinase Increased, Rhabdomyolysis, Hyperthermia, Tachycardia, Coma, Hypernatraemia, Musculoskeletal Stiffness, Mydriasis, Cytolytic Hepatitis, Abnormal Behaviour, Tremor, Lung Disorder, Blood Potassium Decreased, Extrapyramidal Disorder, Antipsychotic Drug Level Above Therapeutic

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-05-31

Patient: male

Reactions: Confusional State, Agitation, Blood Creatine Phosphokinase Increased, Rhabdomyolysis, Hyperthermia, Tachycardia, Coma, Hypernatraemia, Musculoskeletal Stiffness, Mydriasis, Cytolytic Hepatitis, Alanine Aminotransferase Increased, Abnormal Behaviour, Tremor, Lung Disorder, Blood Potassium Decreased, Aspartate Aminotransferase Increased, Extrapyramidal Disorder, Antipsychotic Drug Level Above Therapeutic

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-05-15

Patient: male

Reactions: Agitation, Dyspnoea, Tachycardia, Unresponsive To Stimuli, Coma, Coma Scale Abnormal, Grand MAL Convulsion, Lung Disorder, Blood Creatinine Increased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine
    Dosage: 0.5 df, unk
    Indication: Dementia
    Start date: 2012-04-17
    End date: 2012-04-17

Oxazepam
    Dosage: 3 df, daily
    Indication: Dementia
    Start date: 2012-04-17
    End date: 2012-04-17

Other drugs received by patient: Galantamine Hydrobromide



Possible Clozapine side effects in male

Reported by a consumer/non-health professional from Brazil on 2012-05-14

Patient: male, weighing 70.0 kg (154.0 pounds)

Reactions: Agitation, Confusional State, Pyromania, Restlessness, Drug Ineffective, Abnormal Behaviour, Schizophrenia, Self Injurious Behaviour, Amnesia, Aggression, Violence-Related Symptom, Tooth Disorder, Hallucination

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 250 mg, unk

Clozapine
    Dosage: 350 mg, unk

Clozapine
    Dosage: 275 mg, unk

Clozapine
    Dosage: 100 mg, unk
    Indication: Schizophrenia
    Start date: 2011-05-27

Clozapine
    Dosage: 3 df, qd
    Administration route: Oral
    Start date: 2008-05-01

Clozapine
    Dosage: 300 mg, unk

Clozapine
    Dosage: 400 mg, qd
    Start date: 1994-01-01

Clozapine
    Dosage: 275 mg, unk
    Administration route: Oral
    Indication: Paranoia
    Start date: 1994-01-01

Clozapine
    Dosage: 4 df, unk

Other drugs received by patient: Haldol; Mellaril; Phenergan; Haldol; Amplictil; Neozine; Mallorol Retard; Zyprexa; Risperdal; Amplictil



Possible Clozapine side effects in 43 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-04-27

Patient: 43 year old male

Reactions: Confusional State, Agitation, Pneumonia, Metabolic Acidosis, Hyperglycaemia, General Physical Health Deterioration, Pyrexia, Chronic Obstructive Pulmonary Disease, Respiratory Distress, Dysarthria, Respiratory Arrest, Pulmonary Oedema, Depressed Level of Consciousness, Salivary Hypersecretion, Gait Disturbance

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Quetiapine



Possible Clozapine side effects in 25 year old male

Reported by a physician from France on 2012-04-27

Patient: 25 year old male

Reactions: Colitis Ischaemic, Agitation, Hyperlactacidaemia, Disseminated Intravascular Coagulation, Hepatic Failure, Rash Macular, Multi-Organ Failure, Renal Failure, Sepsis, Circulatory Collapse

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Lepticur
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    End date: 2012-04-07

Quetiapine Fumarate
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    End date: 2012-04-07

Clozapine
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    End date: 2012-04-07

Clopixol
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    End date: 2012-04-07

Other drugs received by patient: Depakote; Lorazepam; Pantoprazole



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-04-25

Patient: male

Reactions: Colitis Ischaemic, Agitation, Abdominal Pain, Hyperlactacidaemia, Disseminated Intravascular Coagulation, Hepatic Failure, Pyrexia, Gastrointestinal Necrosis, Haemodynamic Instability, Multi-Organ Failure, Generalised Erythema, Psychotic Disorder, Renal Failure, Sepsis, Ejection Fraction Decreased, Leukocytosis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 50 mg/day
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    End date: 2012-04-07

Clopixol
    Dosage: 3 df per day
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    End date: 2012-04-07

Xeroquel
    Dosage: 800 mg per day
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    End date: 2012-04-07

Lepticur
    Dosage: 1 df, tid
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    End date: 2012-04-07

Other drugs received by patient: Depakote; Lorazepam; Pantoprazole



Possible Clozapine side effects in 51 year old male

Reported by a pharmacist from United States on 2012-04-25

Patient: 51 year old male, weighing 86.4 kg (190.1 pounds)

Reactions: Confusional State, Agitation, Blood Creatine Phosphokinase Increased, Diet Refusal, Hypotension, Pyrexia, Heart Rate Increased, Neuroleptic Malignant Syndrome, Tardive Dyskinesia, Oxygen Saturation Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 25mg at bedtime oral
    Administration route: Oral
    Indication: Schizophrenia, Disorganised Type
    Start date: 2006-06-01
    End date: 2012-03-01

Solian (Amisulpride) 200mg Sanofi Aventis
    Dosage: 200mg twice a day oral
    Administration route: Oral
    Indication: Schizophrenia, Disorganised Type
    Start date: 2010-04-01
    End date: 2012-03-01

Other drugs received by patient: Aspirin; Lamictal; Fish OIL; Multi-Vitamin; Klonopin; Lithium Carbonate



Possible Clozapine side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-03

Patient: female

Reactions: Akathisia, Movement Disorder, Abdominal Pain, Pruritus, Malaise, Palpitations, Mood Altered, Back Pain, Toxicity To Various Agents, Stress, Delirium, Aggression, Sleep Disorder, Ocular Hyperaemia, Vision Blurred, Parosmia, Speech Disorder, Overdose, Abdominal Distension, Depression, Dyspnoea, Vomiting, Self Injurious Behaviour, Discomfort, Heart Rate Increased, Asthenia, Agitation, Dementia, Headache, Pyrexia, Loss of Consciousness, Off Label Use, Yellow Skin, Muscle Spasms, Panic Reaction, Bowel Movement Irregularity, Pain in Extremity, Hypoaesthesia, Convulsion, Decreased Interest, Insomnia, Choking, Ocular Icterus, Disturbance in Attention, Sleep Apnoea Syndrome, Confusional State, Pain, Bone Pain, Constipation, Suicidal Ideation, Weight Increased, Myalgia, Fatigue, Toothache, Hypersomnia, Tooth Decalcification, Mydriasis, Nausea, Dental Caries, Status Epilepticus, Cognitive Disorder, Drug Prescribing Error, Stupor, Anxiety, Mental Impairment, Psychotic Disorder, Feeling Abnormal, Influenza Like Illness

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Olanzapine
    Dosage: as needed
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2011-11-01

Lithium Carbonate
    Dosage: 900 milligram;

Clozapine
    Dosage: 75 mg in am, 50 mg hs
    Administration route: Oral
    Indication: Psychotic Disorder

Benztropine Mesylate

Other drugs received by patient: Zolpidem Tartrate; Quetiapine



Possible Clozapine side effects in 20 year old female

Reported by a consumer/non-health professional from United Kingdom on 2012-03-30

Patient: 20 year old female

Reactions: Agitation, Drug Dose Omission, Adverse Drug Reaction, Intentional Drug Misuse, Headache, Constipation, Suicidal Ideation, Speech Disorder, Social Avoidant Behaviour, Self-Injurious Ideation, Restlessness, Nausea, Paranoia, Drug Intolerance, Self Injurious Behaviour, Aggression, Irritability, Mental Impairment, Anxiety, Panic Attack, Paradoxical Drug Reaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Seroquel XR
    Administration route: Oral

Vitamin D

Clozapine

Other drugs received by patient: Haloperidol; Lorazepam; Lorazepam; Diazepam; Haloperidol; Diazepam



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-03-29

Patient: 36 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Agitation, Fatigue, Wrong Drug Administered, Pyrexia, Somnolence, Periostitis

Drug(s) suspected as cause:
Clozapine
    Dosage: 1 df, unk
    Administration route: Oral
    Start date: 2011-07-08

Clonazepam
    Dosage: 15 drp, unk
    Administration route: Oral
    Start date: 2011-07-08

Zonegran
    Dosage: 1 df, unk
    Start date: 2011-07-08

Oxazepam
    Dosage: 1 df, unk
    Start date: 2011-07-08

Lamictal
    Dosage: 1 df, unk
    Start date: 2011-07-08

Loxapine
    Dosage: 75 drp, unk
    Administration route: Oral
    Start date: 2011-07-08

Keppra
    Dosage: 1 df, unk
    Start date: 2011-07-08

Other drugs received by patient: Lithium Carbonate; Atarax; Nozinan / NET /; Dipiperon



Possible Clozapine side effects in female

Reported by a consumer/non-health professional from United States on 2012-03-27

Patient: female

Reactions: Abdominal Pain, Movement Disorder, Akathisia, Malaise, Mood Altered, Palpitations, Back Pain, Toxicity To Various Agents, Delirium, Aggression, Sleep Disorder, Ocular Hyperaemia, Vision Blurred, Parosmia, Speech Disorder, Overdose, Abdominal Distension, Depression, Dyspnoea, Vomiting, Self Injurious Behaviour, Discomfort, Heart Rate Increased, Asthenia, Agitation, Dementia, Pyrexia, Headache, Loss of Consciousness, Off Label Use, Yellow Skin, Panic Reaction, Muscle Spasms, Bowel Movement Irregularity, Pain in Extremity, Hypoaesthesia, Convulsion, Decreased Interest, Choking, Insomnia, Ocular Icterus, Disturbance in Attention, Confusional State, Pain, Bone Pain, Constipation, Suicidal Ideation, Weight Increased, Myalgia, Toothache, Hypersomnia, Tooth Decalcification, Mydriasis, Nausea, Dental Caries, Status Epilepticus, Cognitive Disorder, Drug Prescribing Error, Stupor, Anxiety, Mental Impairment, Psychotic Disorder, Feeling Abnormal, Influenza Like Illness

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Olanzapine
    Dosage: as needed
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2011-11-01

Clozapine
    Dosage: 75 mg in am, 50 mg hs
    Administration route: Oral
    Indication: Psychotic Disorder

Lithium Carbonate
    Dosage: 900 milligram;

Benztropine Mesylate

Other drugs received by patient: Quetiapine; Zolpidem Tartrate



Possible Clozapine side effects in female

Reported by a consumer/non-health professional from United States on 2012-03-16

Patient: female

Reactions: Abdominal Pain, Akathisia, Movement Disorder, Agitation, Dementia, Pyrexia, Headache, Loss of Consciousness, Off Label Use, Malaise, Yellow Skin, Mood Altered, Palpitations, Panic Reaction, Muscle Spasms, Bowel Movement Irregularity, Back Pain, Pain in Extremity, Toxicity To Various Agents, Hypoaesthesia, Delirium, Aggression, Convulsion, Decreased Interest, Sleep Disorder, Ocular Hyperaemia, Choking, Insomnia, Vision Blurred, Ocular Icterus, Disturbance in Attention, Parosmia, Confusional State, Bone Pain, Pain, Constipation, Suicidal Ideation, Weight Increased, Myalgia, Speech Disorder, Overdose, Abdominal Distension, Depression, Hypersomnia, Vomiting, Dyspnoea, Mydriasis, Nausea, Cognitive Disorder, Status Epilepticus, Self Injurious Behaviour, Drug Prescribing Error, Stupor, Discomfort, Mental Impairment, Anxiety, Psychotic Disorder, Heart Rate Increased, Feeling Abnormal, Asthenia, Influenza Like Illness

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Benztropine Mesylate

Olanzapine
    Dosage: as needed
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2011-11-01

Clozapine
    Dosage: 75 mg in am, 50 mg hs
    Administration route: Oral
    Indication: Psychotic Disorder

Lithium Carbonate
    Dosage: 900 milligram;

Other drugs received by patient: Quetiapine; Zolpidem Tartrate



Possible Clozapine side effects in 21 year old male

Reported by a pharmacist from United States on 2012-03-16

Patient: 21 year old male, weighing 68.0 kg (149.7 pounds)

Reactions: Agitation, Eye Irritation, Paranoia, Granulocytopenia, Disturbance in Attention, Memory Impairment

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral

Clozapine
    Administration route: Oral

Clozapine
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    Start date: 2008-02-20

Clozapine
    Administration route: Oral
    Start date: 2012-02-08

Clozapine
    Administration route: Oral
    Start date: 2008-01-01
    End date: 2012-02-07



Possible Clozapine side effects in female

Reported by a consumer/non-health professional from United States on 2012-03-12

Patient: female

Reactions: Movement Disorder, Akathisia, Abdominal Pain, Abdominal Discomfort, Palpitations, Mood Altered, Victim of Abuse, Back Pain, Toxicity To Various Agents, Delirium, Aggression, Post-Traumatic Stress Disorder, Thought Blocking, Sleep Disorder, Ocular Hyperaemia, Vision Blurred, Parosmia, Drug Interaction, Speech Disorder, Overdose, Abdominal Distension, Depression, Dyspnoea, Vomiting, Self Injurious Behaviour, Discomfort, Heart Rate Increased, Asthenia, Agitation, Dementia, Headache, Pyrexia, Loss of Consciousness, Off Label Use, Brain Injury, Yellow Skin, Panic Reaction, Muscle Spasms, Bowel Movement Irregularity, Pain in Extremity, Hypoaesthesia, Convulsion, Decreased Interest, Choking, Insomnia, Ocular Icterus, Disturbance in Attention, Confusional State, Pain, Fear, Bone Pain, Constipation, Suicidal Ideation, Weight Increased, Myalgia, Fatigue, Hypersomnia, Refusal of Treatment by Patient, Mydriasis, Nausea, Condition Aggravated, Status Epilepticus, Cognitive Disorder, Stupor, Anxiety, Mental Impairment, Psychotic Disorder, Emotional Poverty, Feeling Abnormal, Influenza Like Illness

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Benztropine Mesylate

Olanzapine
    Dosage: as needed
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2011-11-01

Clozapine
    Dosage: 75 mg in am, 50 mg hs
    Administration route: Oral
    Indication: Psychotic Disorder

Lithium Carbonate
    Dosage: 900 milligram;

Other drugs received by patient: Zolpidem Tartrate; Quetiapine



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-03-07

Patient: male

Reactions: Confusional State, Agitation, Aphasia, Pyrexia, Disorientation, Fall, Pallor, Electroencephalogram Abnormal, Speech Disorder, Malaise, C-Reactive Protein Increased, Skin Lesion, Crepitations, Heart Rate Irregular, White Blood Cell Count Increased, Tachyarrhythmia, Atrial Fibrillation, General Physical Health Deterioration, Abnormal Behaviour, Rash, Computerised Tomogram Abnormal, Diastolic Hypotension, Mitral Valve Incompetence, Insomnia, RED Blood Cell Sedimentation Rate Increased, Fibrin Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Exelon; Aspirin; Tercian; Diclofenac Sodium



Possible Clozapine side effects in female

Reported by a consumer/non-health professional from United States on 2012-02-24

Patient: female

Reactions: Agitation, Movement Disorder, Akathisia, Dementia, Pyrexia, Headache, Loss of Consciousness, Off Label Use, Abdominal Discomfort, Mood Altered, Yellow Skin, Palpitations, Muscle Spasms, Panic Reaction, Back Pain, Pain in Extremity, Hypoaesthesia, Toxicity To Various Agents, Delirium, Convulsion, Aggression, Insomnia, Choking, Ocular Hyperaemia, Ocular Icterus, Disturbance in Attention, Vision Blurred, Parosmia, Confusional State, Pain, Constipation, Suicidal Ideation, Myalgia, Speech Disorder, Weight Increased, Overdose, Hypersomnia, Dyspnoea, Mydriasis, Vomiting, Nausea, Self Injurious Behaviour, Cognitive Disorder, Status Epilepticus, Stupor, Mental Impairment, Anxiety, Psychotic Disorder, Heart Rate Increased, Asthenia, Feeling Abnormal, Influenza Like Illness

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Benztropine Mesylate

Lithium Carbonate
    Dosage: 900 milligram;

Clozapine
    Dosage: 75 mg in am, 50 mg hs
    Administration route: Oral
    Indication: Psychotic Disorder

Olanzapine
    Dosage: as needed
    Administration route: Oral
    Indication: Psychotic Disorder
    Start date: 2011-11-01

Other drugs received by patient: Quetiapine; Zolpidem Tartrate



Possible Clozapine side effects in 21 year old male

Reported by a pharmacist from United States on 2012-02-23

Patient: 21 year old male

Reactions: Agitation, Paranoia, Eye Irritation, Granulocytopenia, Disturbance in Attention, Memory Impairment

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Start date: 2012-02-08

Clozapine
    Administration route: Oral
    Start date: 2012-02-08

Clozapine
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    Start date: 2009-01-01
    End date: 2012-02-07

Clozapine
    Administration route: Oral
    Start date: 2009-01-01
    End date: 2012-02-07



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-02-16

Patient: male

Reactions: Agitation, Confusional State, Akathisia, Blood Creatine Phosphokinase Increased, Hyperthermia, Mutism, Urinary Incontinence, Pyrexia, Hyperhidrosis, Muscle Rigidity, Neuroleptic Malignant Syndrome, White Blood Cell Count Increased, Neutrophil Count Increased, Dysphagia, Viral Infection, Delirium Tremens, Alanine Aminotransferase Increased, Akinesia, Psychotic Disorder, Hypophagia, Heart Rate Increased, Dehydration, Depressed Level of Consciousness, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Atorvastatin; Esomeprazole; Acetylcysteine; Bendroflumethiazide; Aspirin



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-02-16

Patient: male

Reactions: Confusional State, Akathisia, Agitation, Blood Creatine Phosphokinase Increased, Mutism, Hyperthermia, Urinary Incontinence, Pyrexia, Hyperhidrosis, Muscle Rigidity, Neuroleptic Malignant Syndrome, White Blood Cell Count Increased, Viral Infection, Neutrophil Count Increased, Dysphagia, Delirium Tremens, Alanine Aminotransferase Increased, Akinesia, Psychotic Disorder, Dehydration, Hypophagia, Heart Rate Increased, Depressed Level of Consciousness, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Atorvastatin; Acetylsalicylic Acid SRT; Acetylcysteine; Bendroflumethiazide; Esomeprazole



Possible Clozapine side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-14

Patient:

Reactions: Agitation, Psychotic Disorder, Neutrophil Count Increased, Leukocytosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 12.5 mg, bid

Clozapine
    Dosage: 300 mg daily

Clozapine
    Dosage: 400 mg,daily

Other drugs received by patient: Risperidone



Possible Clozapine side effects in female

Reported by a consumer/non-health professional from Brazil on 2012-02-14

Patient: female

Reactions: Agitation, Malaise, Abnormal Behaviour, Hallucination, Tremor

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 500 mg (5 tablets)
    Administration route: Oral

Clozapine
    Dosage: 450 mg, a day (4 tablets and half)
    Administration route: Oral

Clozapine
    Dosage: 500 mg, unk

Clozapine
    Dosage: 100 mg, unk

Clozapine
    Dosage: 100 mg, 1 tablet a day
    Administration route: Oral
    Indication: Schizophrenia

Other drugs received by patient: Topiramate; Akineton



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