DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Clolar (Clofarabine) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (12)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clolar (Clofarabine) life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female, weighing 25.0 kg (55.0 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Respiratory Failure, Cardiac Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: 70 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: 229.9 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: 254 mg, qd
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Busulfan; Thiotepa; Dilaudid; Meropenem; Cytarabine; Melphalan Hydrochloride; Fentanyl Citrate



Possible Clolar side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-21

Patient: male, weighing 115.0 kg (253.0 pounds)

Reactions: Dyspnoea, Pneumonia, Haemoptysis, Rales, Musculoskeletal Pain, Hypotension, Pyrexia, Atrioventricular Block Second Degree, Lung Consolidation, Pulmonary Haemorrhage, Chest Pain, Tachypnoea, Pleural Effusion, Cough

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Busulfan
    Dosage: unk
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-08-04
    End date: 2012-08-08

Clolar
    Dosage: unk
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-08-03
    End date: 2012-08-08

Other drugs received by patient: Vancomycin; Zosyn; Micafungin; Voriconazole; Tacrolimus; Oxycodone HCL; Antibiotics; Methotrexate; Azithromycin; Neupogen; Coreg



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female, weighing 25.0 kg (55.0 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Cardiac Failure, Respiratory Failure, Sepsis, Pleural Effusion, Hypertension, Fusarium Infection

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: 70 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: 254 mg, qd
    Start date: 2012-06-16
    End date: 2012-06-19

Thymoglobulin
    Dosage: 229.9 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Other drugs received by patient: Meropenem; Fentanyl Citrate; Cytarabine; Thiotepa; Melphalan Hydrochloride; Dilaudid; Busulfan



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-16

Patient: female, weighing 25.2 kg (55.4 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Cardiac Failure, Respiratory Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: unk
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Melphalan Hydrochloride; Busulfan; Fentanyl; Thiotepa; Cytarabine; Dilaudid; Meropenem



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-13

Patient: female, weighing 25.2 kg (55.4 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Respiratory Failure, Cardiac Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: unk
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Meropenem; Melphalan Hydrochloride; Cytarabine; Busulfan; Dilaudid; Fentanyl; Thiotepa



Possible Clolar side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-17

Patient: male, weighing 116.6 kg (256.5 pounds)

Reactions: Renal Failure, Pneumonia, Neutropenic Colitis, Neutropenic Sepsis, Hypotension, Pleural Effusion, Mental Status Changes, Staphylococcal Bacteraemia, Pulseless Electrical Activity

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Busulfan
    Dosage: 249 mg, once
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-03-30
    End date: 2012-03-31

Busulfan
    Dosage: 390 mg, once
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-04-01
    End date: 2012-04-02

Clolar
    Dosage: 94 mg, once
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-03-29
    End date: 2012-04-02

Clolar
    Indication: Bone Marrow Conditioning Regimen



Possible Clolar side effects in 8 year old male

Reported by a physician from Colombia on 2011-12-02

Patient: 8 year old male, weighing 19.0 kg (41.8 pounds)

Reactions: Diarrhoea, Dysuria, Pyrexia, Staphylococcal Sepsis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clolar
    Dosage: 40 mg/m2, qdx5
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-02-01

Cyclophosphamide
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Etoposide
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia



Possible Clolar side effects in female

Reported by a physician from United States on 2011-12-02

Patient: female, weighing 53.0 kg (116.6 pounds)

Reactions: Thrombosis, Hepatic Function Abnormal, Citrobacter Infection, Hyperbilirubinaemia, Atrial Flutter, Pulmonary Alveolar Haemorrhage, Cerebral Ischaemia, Mucosal Inflammation, Renal Failure, Neoplasm Malignant, Acute Respiratory Distress Syndrome, Acute Respiratory Failure, Hypertension

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Clolar
    Dosage: 20 mg/m2, qdx5
    Indication: Acute Myeloid Leukaemia
    Start date: 2010-11-15
    End date: 2010-11-19

Melphalan Hydrochloride
    Dosage: 110 mg, unk
    Indication: Acute Myeloid Leukaemia
    Start date: 2010-11-21
    End date: 2010-11-22

Thiotepa
    Dosage: 600 mg, unk
    Indication: Acute Myeloid Leukaemia
    Start date: 2010-11-20
    End date: 2010-11-20

Other drugs received by patient: Tacrolimus; Filgrastim; Mycophenolate Mofetil; Methotrexate; Methotrexate; Mycophenolate Mofetil



Possible Clolar side effects in 36 year old female

Reported by a physician from Mexico on 2011-10-25

Patient: 36 year old female, weighing 78.0 kg (171.6 pounds)

Reactions: Acute Myeloid Leukaemia, Bone Marrow Failure

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Clolar
    Dosage: 40 mg/m2, qdx5
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-04-12
    End date: 2011-05-01

Cytarabine
    Dosage: 1 g/m2, qdx5
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-04-12
    End date: 2011-04-16

Other drugs received by patient: Neupogen



Possible Clolar side effects in 36 year old female

Reported by a physician from Mexico on 2011-10-20

Patient: 36 year old female, weighing 78.0 kg (171.6 pounds)

Reactions: Acute Myeloid Leukaemia, Bone Marrow Failure

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Clolar
    Dosage: 40 mg/m2, qdx5
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-04-12
    End date: 2011-05-01

Cytarabine
    Dosage: 1 g/m2, qdx5
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-04-12
    End date: 2011-04-16

Other drugs received by patient: Neupogen



Possible Clolar side effects in 36 year old female

Reported by a physician from Mexico on 2011-10-17

Patient: 36 year old female, weighing 78.0 kg (171.6 pounds)

Reactions: Acute Myeloid Leukaemia, Bone Marrow Failure

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Clolar
    Dosage: 40 mg/m2, qdx5
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-05-01
    End date: 2011-05-01

Cytarabine
    Dosage: 1 g/m2, qdx5
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-04-12
    End date: 2011-04-16

Other drugs received by patient: Neupogen



Possible Clolar side effects in 8 year old male

Reported by a physician from Colombia on 2011-10-11

Patient: 8 year old male, weighing 19.0 kg (41.8 pounds)

Reactions: Escherichia Test Positive, Bacteraemia, Diarrhoea, Dysuria, Pyrexia, Culture Urine Positive, Staphylococcal Sepsis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clolar
    Dosage: 40 mg/m2, qdx5
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-02-01

Cyclosporine
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Etoposide
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017