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Clolar (Clofarabine) - Death - Suspected Cause - Side Effect Reports

 
 



Index of reports > Death (67)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clolar (Clofarabine) death. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 67   Next >>

Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female, weighing 25.0 kg (55.0 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Respiratory Failure, Cardiac Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Thymoglobulin
    Dosage: 229.9 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: 254 mg, qd
    Start date: 2012-06-16
    End date: 2012-06-19

Clolar
    Dosage: 70 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Other drugs received by patient: Busulfan; Thiotepa; Dilaudid; Meropenem; Cytarabine; Melphalan Hydrochloride; Fentanyl Citrate



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female, weighing 25.0 kg (55.0 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Cardiac Failure, Respiratory Failure, Sepsis, Pleural Effusion, Hypertension, Fusarium Infection

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Clolar
    Dosage: 70 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Thymoglobulin
    Dosage: 254 mg, qd
    Start date: 2012-06-16
    End date: 2012-06-19

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Thymoglobulin
    Dosage: 229.9 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Other drugs received by patient: Meropenem; Fentanyl Citrate; Cytarabine; Thiotepa; Melphalan Hydrochloride; Dilaudid; Busulfan



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-16

Patient: female

Reactions: Pyrexia, Pupils Unequal, Cerebral Ischaemia, Pleural Effusion, Brain Oedema, Intracranial Pressure Increased, Staphylococcal Bacteraemia, Pupil Fixed, Blood Pressure Systolic Decreased, Pupillary Reflex Impaired, Cerebral Artery Stenosis, Brain Stem Haemorrhage, Brain Herniation, Hyperreflexia, Ascites, Convulsion, Venoocclusive Disease, Bacteraemia, Respiratory Failure, Meningitis Bacterial, Mental Disorder, Acute Myeloid Leukaemia Recurrent

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-07-12

Clolar
    Dosage: 52 mg/m2, dose level 3
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-07-13
    End date: 2012-07-17



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-16

Patient: female, weighing 25.2 kg (55.4 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Cardiac Failure, Respiratory Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Thymoglobulin
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: unk
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Melphalan Hydrochloride; Busulfan; Fentanyl; Thiotepa; Cytarabine; Dilaudid; Meropenem



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-13

Patient: female, weighing 25.2 kg (55.4 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Respiratory Failure, Cardiac Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Thymoglobulin
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: unk
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Meropenem; Melphalan Hydrochloride; Cytarabine; Busulfan; Dilaudid; Fentanyl; Thiotepa



Possible Clolar side effects in female

Reported by a physician from Australia on 2012-07-19

Patient: female

Reactions: Atrial Fibrillation, Febrile Neutropenia, Constipation, Delusion, Haemoglobin Decreased, Fatigue, Myocardial Infarction, Hallucination, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Acute Myeloid Leukaemia
    Start date: 2010-10-25
    End date: 2010-10-29

Clolar
    Dosage: unk
    Start date: 2010-11-29
    End date: 2010-12-03

Other drugs received by patient: Metformin Hydrochloride



Possible Clolar side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-15

Patient: male, weighing 83.4 kg (183.5 pounds)

Reactions: Hepatic Failure

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clolar

Other drugs received by patient: Acyclovir; Fluconazole; Ceftazidime; Filgrastim; Voriconazole



Possible Clolar side effects in 11 year old male

Reported by a physician from Argentina on 2012-06-14

Patient: 11 year old male

Reactions: Multi-Organ Failure, Cardiac Failure, Hypotension, Sepsis, Electrolyte Imbalance

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar
    Dosage: unk

Cyclophosphamide
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Cyclophosphamide
    Dosage: unk

Etoposide
    Dosage: unk

Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Etoposide
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia



Possible Clolar side effects in male

Reported by a physician from United States on 2012-06-04

Patient: male, weighing 83.4 kg (183.5 pounds)

Reactions: Hyperbilirubinaemia, Hypoalbuminaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clolar

Other drugs received by patient: Voriconazole; Acyclovir; Ceftazidime; Filgrastim; Fluconazole



Possible Clolar side effects in 12 year old female

Reported by a physician from Argentina on 2012-05-25

Patient: 12 year old female

Reactions: Acute Lymphocytic Leukaemia, Neutropenia, Pyrexia

Adverse event resulted in: death

Drug(s) suspected as cause:
Etoposide
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-07-01

Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-07-01

Cytoxan
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-07-01



Possible Clolar side effects in male

Reported by a physician from Argentina on 2012-05-23

Patient: male

Reactions: Acute Lymphocytic Leukaemia, Device Related Sepsis, Vomiting, Rash Erythematous, Febrile Neutropenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Etoposide
    Dosage: 150 mg/m2, qdx5
    Indication: Acute Lymphocytic Leukaemia

Cyclophosphamide
    Dosage: 440 mg/m2, qdx5
    Indication: Acute Lymphocytic Leukaemia

Clolar
    Dosage: 40 mg/m2, qdx5
    Indication: Acute Lymphocytic Leukaemia



Possible Clolar side effects in 7 year old female

Reported by a physician from Argentina on 2012-05-15

Patient: 7 year old female

Reactions: Acute Lymphocytic Leukaemia, Pigmentation Disorder, Bone Marrow Failure

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar
    Dosage: 40 mg/m2, qdx5

Cyclophosphamide
    Dosage: 440 mg/m2, qdx5

Etoposide
    Dosage: 150 mg/m2, qdx5
    Indication: Acute Lymphocytic Leukaemia Recurrent

Cyclophosphamide
    Dosage: 440 mg/m2, qdx5
    Indication: Acute Lymphocytic Leukaemia Recurrent

Clolar
    Dosage: 40 mg/m2, qdx5
    Indication: Acute Lymphocytic Leukaemia Recurrent

Etoposide
    Dosage: 150 mg/m2, qdx5



Possible Clolar side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-25

Patient: female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar



Possible Clolar side effects in male

Reported by a physician from United States on 2012-04-24

Patient: male, weighing 90.0 kg (198.0 pounds)

Reactions: Cardio-Respiratory Arrest, Mouth Haemorrhage, Unresponsive To Stimuli, Febrile Neutropenia, Pleural Effusion, Pancytopenia, Pneumonitis

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar



Possible Clolar side effects in female

Reported by a physician from United States on 2012-04-24

Patient: female, weighing 41.7 kg (91.7 pounds)

Reactions: Contusion, Skin Exfoliation, Pyrexia, Haematemesis, Oral Candidiasis, Skin Discolouration, Epistaxis, Blood Pressure Increased, Swelling Face, Stomatitis, Vomiting, Pain in Extremity, Nausea, Acute Lymphocytic Leukaemia, Renal Failure, Diarrhoea

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clolar

Other drugs received by patient: Promethazine; Vinorelbine; Zosyn; Linezolid; Amphojel; Meropenem; Nystatin; Norvasc; Octreotide Acetate; Dexamethasone; Vinorelbine; Caphosol; Vinorelbine; Pepcid; Zoloft; Bactrim; Caspofungin Acetate; Thiotepa; RED Blood Cells, Concentrated; Platelets; Allopurinol; Acyclovir; Solutions FOR Parenteral Nutrition; Oxycodone HCL; Neupogen; Ondansetron; Lorazepam; Zithromax; Vfend; Vancomycin; Octreotide Acetate; Topotecan; Cefepime; Imodium; Dexamethasone; D5 1 / 2 NS + KCL 20 MEQ / L; Imodium



Possible Clolar side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-17

Patient: male, weighing 116.6 kg (256.5 pounds)

Reactions: Renal Failure, Pneumonia, Neutropenic Colitis, Neutropenic Sepsis, Hypotension, Pleural Effusion, Mental Status Changes, Staphylococcal Bacteraemia, Pulseless Electrical Activity

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Clolar
    Dosage: 94 mg, once
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-03-29
    End date: 2012-04-02

Busulfan
    Dosage: 249 mg, once
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-03-30
    End date: 2012-03-31

Clolar
    Indication: Bone Marrow Conditioning Regimen

Busulfan
    Dosage: 390 mg, once
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-04-01
    End date: 2012-04-02



Possible Clolar side effects in female

Reported by a physician from United States on 2012-04-11

Patient: female, weighing 41.7 kg (91.7 pounds)

Reactions: Contusion, Skin Exfoliation, Pyrexia, Haematemesis, Oral Candidiasis, Skin Discolouration, Epistaxis, Blood Pressure Increased, Swelling Face, Vomiting, Nausea, Pain in Extremity, Acute Lymphocytic Leukaemia, Mucosal Inflammation, Renal Failure, Diarrhoea

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clolar

Other drugs received by patient: D5 1 / 2 NS + KCL 20 MEQ / L; Vfend; Pepcid; Zoloft; Solutions FOR Parenteral Nutrition; Imodium; Thiotepa; Ondansetron; Lorazepam; Vinorelbine; Vinorelbine; Zosyn; Zithromax; Norvasc; Bactrim; Octreotide Acetate; Oxycodone HCL; Acyclovir; Caphosol; Neupogen; Promethazine; Nystatin; Platelets; Cefepime; Imodium; RED Blood Cells, Concentrated; Allopurinol; Vinorelbine; Amphojel; Meropenem; Vancomycin; Dexamethasone; Dexamethasone; Topotecan; Linezolid; Caspofungin Acetate; Octreotide Acetate



Possible Clolar side effects in

Reported by a consumer/non-health professional from United States on 2012-04-09

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar



Possible Clolar side effects in

Reported by a consumer/non-health professional from United States on 2012-04-03

Patient:

Reactions: Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Cytarabine
    Dosage: unk
    Indication: Product Used FOR Unknown Indication



Possible Clolar side effects in

Reported by a pharmacist from United States on 2012-04-02

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar



Possible Clolar side effects in

Reported by a pharmacist from United States on 2012-03-30

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar



Possible Clolar side effects in

Reported by a physician from United States on 2012-03-30

Patient:

Reactions: Death, Fall

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar



Possible Clolar side effects in

Reported by a consumer/non-health professional from United States on 2012-03-30

Patient:

Reactions: Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Cytarabine
    Dosage: unk
    Indication: Product Used FOR Unknown Indication



Possible Clolar side effects in

Reported by a consumer/non-health professional from United States on 2012-03-30

Patient:

Reactions: Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Cytarabine
    Dosage: unk
    Indication: Product Used FOR Unknown Indication



Possible Clolar side effects in

Reported by a consumer/non-health professional from United States on 2012-03-29

Patient:

Reactions: Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cytarabine
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Clolar
    Dosage: unk
    Indication: Product Used FOR Unknown Indication



Possible Clolar side effects in 62 year old male

Reported by a physician from United States on 2012-03-28

Patient: 62 year old male, weighing 71.0 kg (156.2 pounds)

Reactions: Multi-Organ Failure, Sepsis, Acute Myeloid Leukaemia, Septic Shock

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clolar
    Dosage: 37.2 mg, unk
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-01-24

Clolar
    Dosage: 37.2 mg, unk
    Start date: 2012-02-17
    End date: 2012-02-17



Possible Clolar side effects in male

Reported by a consumer/non-health professional from United States on 2012-03-28

Patient: male, weighing 71.0 kg (156.2 pounds)

Reactions: Transfusion-Related Acute Lung Injury, Sepsis, Acute Respiratory Distress Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clolar
    Dosage: 20 mg/m2, qdx5 consolidation
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-01-23
    End date: 2012-01-27

Clolar
    Dosage: cycle ii of induction
    Start date: 2011-10-25
    End date: 2011-10-28

Clolar
    Dosage: cycle i of induction
    Start date: 2011-10-04
    End date: 2011-10-08

Other drugs received by patient: Ciprofloxacin HCL; Voriconazole; Oxycodone HCL; Ondansetron; Ondansetron; Compazine; Compazine



Possible Clolar side effects in male

Reported by a individual with unspecified qualification from United States on 2012-03-22

Patient: male, weighing 93.1 kg (204.8 pounds)

Reactions: Hypoxia, Acute Lymphocytic Leukaemia Recurrent, Cardiac Arrest, Influenza

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: 8000 mg
    End date: 2012-03-06

Clolar
    Dosage: 240 mg
    End date: 2012-03-02



Possible Clolar side effects in male

Reported by a consumer/non-health professional from United States on 2012-03-16

Patient: male, weighing 71.0 kg (156.2 pounds)

Reactions: Transfusion-Related Acute Lung Injury, Sepsis, Acute Respiratory Distress Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clolar
    Dosage: 20 mg/m2, qdx5 consolidation
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-01-23
    End date: 2012-01-27

Clolar
    Dosage: cycle i of induction
    Start date: 2011-10-04
    End date: 2011-10-08

Clolar
    Dosage: cycle ii of induction
    Start date: 2011-10-25
    End date: 2011-10-28

Other drugs received by patient: Voriconazole; Ondansetron; Ondansetron; Compazine; Oxycodone HCL; Compazine; Ciprofloxacin Hydrochloride



Possible Clolar side effects in

Reported by a physician from United States on 2012-03-09

Patient:

Reactions: Death, Fall

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar



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