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Index of reports
> Cases with Pyrexia (16)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clolar (Clofarabine) where reactions include pyrexia. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Clolar side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24
Patient: male, weighing 121.9 kg (268.2 pounds)
Reactions: Pruritus, Unresponsive To Stimuli, Device Related Infection, Pyrexia, Candidiasis, Abscess Limb, Ventricular Extrasystoles, Metabolic Acidosis, Dyspnoea, Hypotension, Pancytopenia, Tremor, Convulsion, Respiratory Failure, Fungal Infection, Ventricular Tachycardia, Sepsis, Respiratory Arrest, Pulse Absent, Sinus Tachycardia, Hypertension, Feeling Abnormal, Cardiac Arrest, Escherichia Infection, Infusion Related Reaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Epinephrine
Dosage: 4 df, unk
Indication: Cardiac Arrest
Start date: 2012-07-14
End date: 2012-07-14
Cyclophosphamide
Dosage: daily for 5 days
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-06-19
End date: 2012-06-23
Oncaspar
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-07-02
End date: 2012-07-02
Epinephrine
Dosage: unk
Start date: 2012-07-14
End date: 2012-07-14
Clolar
Dosage: 74.4 mg, qd
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-06-19
End date: 2012-06-23
Etoposide
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-06-19
End date: 2012-06-23
Vincristine Sulfate
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-07-02
End date: 2012-07-02
Other drugs received by patient: Colace; Bactrim; Stomatitis Mouthwash; Prilosec; Lortab; Cymbalta; Ondansetron; Ambien
Possible Clolar side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-21
Patient: male, weighing 115.0 kg (253.0 pounds)
Reactions: Dyspnoea, Pneumonia, Haemoptysis, Rales, Musculoskeletal Pain, Hypotension, Pyrexia, Atrioventricular Block Second Degree, Lung Consolidation, Pulmonary Haemorrhage, Chest Pain, Tachypnoea, Pleural Effusion, Cough
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Busulfan
Dosage: unk
Indication: Acute Myeloid Leukaemia
Start date: 2012-08-04
End date: 2012-08-08
Clolar
Dosage: unk
Indication: Acute Myeloid Leukaemia
Start date: 2012-08-03
End date: 2012-08-08
Other drugs received by patient: Vancomycin; Zosyn; Micafungin; Voriconazole; Tacrolimus; Oxycodone HCL; Antibiotics; Methotrexate; Azithromycin; Neupogen; Coreg
Possible Clolar side effects in female
Reported by a physician from United States on 2012-08-16
Patient: female
Reactions: Pyrexia, Pupils Unequal, Cerebral Ischaemia, Pleural Effusion, Brain Oedema, Intracranial Pressure Increased, Staphylococcal Bacteraemia, Pupil Fixed, Blood Pressure Systolic Decreased, Pupillary Reflex Impaired, Cerebral Artery Stenosis, Brain Stem Haemorrhage, Brain Herniation, Hyperreflexia, Ascites, Convulsion, Venoocclusive Disease, Bacteraemia, Respiratory Failure, Meningitis Bacterial, Mental Disorder, Acute Myeloid Leukaemia Recurrent
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Cytarabine
Dosage: unk
Indication: Bone Marrow Conditioning Regimen
Start date: 2012-07-12
Clolar
Dosage: 52 mg/m2, dose level 3
Indication: Bone Marrow Conditioning Regimen
Start date: 2012-07-13
End date: 2012-07-17
Possible Clolar side effects in 12 year old female
Reported by a physician from Argentina on 2012-05-25
Patient: 12 year old female
Reactions: Acute Lymphocytic Leukaemia, Neutropenia, Pyrexia
Adverse event resulted in: death
Drug(s) suspected as cause:
Etoposide
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-07-01
Clolar
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-07-01
Cytoxan
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-07-01
Possible Clolar side effects in female
Reported by a physician from United States on 2012-04-24
Patient: female, weighing 41.7 kg (91.7 pounds)
Reactions: Contusion, Skin Exfoliation, Pyrexia, Haematemesis, Oral Candidiasis, Skin Discolouration, Epistaxis, Blood Pressure Increased, Swelling Face, Stomatitis, Vomiting, Pain in Extremity, Nausea, Acute Lymphocytic Leukaemia, Renal Failure, Diarrhoea
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Clolar
Other drugs received by patient: Promethazine; Vinorelbine; Zosyn; Linezolid; Amphojel; Meropenem; Nystatin; Norvasc; Octreotide Acetate; Dexamethasone; Vinorelbine; Caphosol; Vinorelbine; Pepcid; Zoloft; Bactrim; Caspofungin Acetate; Thiotepa; RED Blood Cells, Concentrated; Platelets; Allopurinol; Acyclovir; Solutions FOR Parenteral Nutrition; Oxycodone HCL; Neupogen; Ondansetron; Lorazepam; Zithromax; Vfend; Vancomycin; Octreotide Acetate; Topotecan; Cefepime; Imodium; Dexamethasone; D5 1 / 2 NS + KCL 20 MEQ / L; Imodium
Possible Clolar side effects in female
Reported by a physician from United States on 2012-04-11
Patient: female, weighing 41.7 kg (91.7 pounds)
Reactions: Contusion, Skin Exfoliation, Pyrexia, Haematemesis, Oral Candidiasis, Skin Discolouration, Epistaxis, Blood Pressure Increased, Swelling Face, Vomiting, Nausea, Pain in Extremity, Acute Lymphocytic Leukaemia, Mucosal Inflammation, Renal Failure, Diarrhoea
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Clolar
Other drugs received by patient: D5 1 / 2 NS + KCL 20 MEQ / L; Vfend; Pepcid; Zoloft; Solutions FOR Parenteral Nutrition; Imodium; Thiotepa; Ondansetron; Lorazepam; Vinorelbine; Vinorelbine; Zosyn; Zithromax; Norvasc; Bactrim; Octreotide Acetate; Oxycodone HCL; Acyclovir; Caphosol; Neupogen; Promethazine; Nystatin; Platelets; Cefepime; Imodium; RED Blood Cells, Concentrated; Allopurinol; Vinorelbine; Amphojel; Meropenem; Vancomycin; Dexamethasone; Dexamethasone; Topotecan; Linezolid; Caspofungin Acetate; Octreotide Acetate
Possible Clolar side effects in male
Reported by a physician from Argentina on 2012-01-16
Patient: male
Reactions: Acute Lymphocytic Leukaemia, Neutropenia, Pyrexia
Adverse event resulted in: death
Drug(s) suspected as cause:
Clolar
Dosage: 40 mg/m2, qd
Indication: Acute Lymphocytic Leukaemia
Etoposide
Dosage: 150 mg/m2, unk
Indication: Acute Lymphocytic Leukaemia
Cyclophosphamide
Dosage: 440 mg/m2, unk
Indication: Acute Lymphocytic Leukaemia
Possible Clolar side effects in male
Reported by a physician from Argentina on 2012-01-16
Patient: male
Reactions: Acute Lymphocytic Leukaemia, Fanconi Syndrome, Pyrexia, Neutropenia
Adverse event resulted in: death
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: 440 mg/m2, qdx5
Indication: Acute Lymphocytic Leukaemia Recurrent
Clolar
Dosage: 40 mg/m2, qdx5
Indication: Acute Lymphocytic Leukaemia Recurrent
Etoposide
Dosage: 150 mg/m2, qdx5
Indication: Acute Lymphocytic Leukaemia Recurrent
Possible Clolar side effects in male
Reported by a physician from Argentina on 2012-01-13
Patient: male
Reactions: Acute Lymphocytic Leukaemia, Fanconi Syndrome, Pyrexia, Neutropenia
Adverse event resulted in: death
Drug(s) suspected as cause:
Clolar
Dosage: 40 mg/m2, qdx5
Indication: Acute Lymphocytic Leukaemia Recurrent
Etoposide
Dosage: 150 mg/m2, qdx5
Indication: Acute Lymphocytic Leukaemia Recurrent
Cyclophosphamide
Dosage: 440 mg/m2, qdx5
Indication: Acute Lymphocytic Leukaemia Recurrent
Possible Clolar side effects in male
Reported by a physician from Argentina on 2012-01-12
Patient: male
Reactions: Acute Lymphocytic Leukaemia, Drug Ineffective, Neutropenia, Pyrexia
Adverse event resulted in: death
Drug(s) suspected as cause:
Etoposide
Dosage: 150 mg/m2, qdx5, 1cycle
Indication: Acute Lymphocytic Leukaemia
Clolar
Dosage: 40 mg/m2, qdx5 1 cycle
Indication: Acute Lymphocytic Leukaemia
Cyclophosphamide
Dosage: 440 mg/m2, qdx5 1 cycle
Indication: Acute Lymphocytic Leukaemia
Possible Clolar side effects in female
Reported by a physician from Argentina on 2012-01-12
Patient: female
Reactions: Acute Lymphocytic Leukaemia, Neoplasm Progression, Neutropenia, Pyrexia
Adverse event resulted in: death
Drug(s) suspected as cause:
Clolar
Other drugs received by patient: Etoposide; Cyclophosphamide
Possible Clolar side effects in male
Reported by a physician from Argentina on 2012-01-12
Patient: male
Reactions: Acute Lymphocytic Leukaemia Recurrent, Neutropenia, Pyrexia, Rash Pruritic
Adverse event resulted in: death
Drug(s) suspected as cause:
Clolar
Dosage: 40 mg/m2, qdx5 (1 cycle)
Clolar
Dosage: 40 mg/m2, 1 cycle
Indication: Acute Lymphocytic Leukaemia Recurrent
Other drugs received by patient: Etoposide; Cyclophosphamide
Possible Clolar side effects in 8 year old male
Reported by a physician from Colombia on 2011-12-02
Patient: 8 year old male, weighing 19.0 kg (41.8 pounds)
Reactions: Diarrhoea, Dysuria, Pyrexia, Staphylococcal Sepsis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Clolar
Dosage: 40 mg/m2, qdx5
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-02-01
Cyclophosphamide
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Etoposide
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Possible Clolar side effects in 11 year old female
Reported by a physician from Colombia on 2011-11-30
Patient: 11 year old female, weighing 35.0 kg (77.0 pounds)
Reactions: Large Intestine Perforation, Stomatitis, Neutropenic Colitis, Anaemia, Febrile Neutropenia, Pyrexia, Klebsiella Bacteraemia, Burkholderia Cepacia Complex Sepsis, Thrombocytopenia, Sinusitis, Leukopenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Clolar
Dosage: 60 mg (52 mg/m2), qdx5 (cycle 1)
Indication: Acute Lymphocytic Leukaemia
Clolar
Dosage: 60 mg (52 mg/m2), qdx5 (cycle 2)
Other drugs received by patient: Acetaminophen; Hydrocortisone; Hydroxyzine; Ranitidine; Ondansetron
Possible Clolar side effects in 8 year old male
Reported by a physician from Colombia on 2011-10-11
Patient: 8 year old male, weighing 19.0 kg (41.8 pounds)
Reactions: Escherichia Test Positive, Bacteraemia, Diarrhoea, Dysuria, Pyrexia, Culture Urine Positive, Staphylococcal Sepsis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Cyclosporine
Dosage: unk
Indication: Product Used FOR Unknown Indication
Etoposide
Dosage: unk
Indication: Product Used FOR Unknown Indication
Clolar
Dosage: 40 mg/m2, qdx5
Indication: Product Used FOR Unknown Indication
Start date: 2011-02-01
Possible Clolar side effects in 11 year old female
Reported by a physician from Colombia on 2011-10-11
Patient: 11 year old female, weighing 35.0 kg (77.0 pounds)
Reactions: Large Intestine Perforation, Neutropenic Colitis, Stomatitis, Anaemia, Febrile Neutropenia, Pyrexia, Klebsiella Bacteraemia, Death, Thrombocytopenia, Sinusitis, Leukopenia
Adverse event resulted in: death
Drug(s) suspected as cause:
Clolar
Dosage: 60 mg (52 mg/m2), qdx5 (cycle 1)
Indication: Acute Lymphocytic Leukaemia
Clolar
Dosage: 60 mg (52 mg/m2), qdx5 (cycle 2)
Other drugs received by patient: Hydrocortisone; Ondansetron; Acetaminophen; Hydroxyzine; Ranitidine
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