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Clolar (Clofarabine) - Pleural Effusion - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Pleural Effusion (9)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clolar (Clofarabine) where reactions include pleural effusion. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female, weighing 25.0 kg (55.0 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Respiratory Failure, Cardiac Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: 70 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: 229.9 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: 254 mg, qd
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Busulfan; Thiotepa; Dilaudid; Meropenem; Cytarabine; Melphalan Hydrochloride; Fentanyl Citrate



Possible Clolar side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-21

Patient: male, weighing 115.0 kg (253.0 pounds)

Reactions: Dyspnoea, Pneumonia, Haemoptysis, Rales, Musculoskeletal Pain, Hypotension, Pyrexia, Atrioventricular Block Second Degree, Lung Consolidation, Pulmonary Haemorrhage, Chest Pain, Tachypnoea, Pleural Effusion, Cough

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Busulfan
    Dosage: unk
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-08-04
    End date: 2012-08-08

Clolar
    Dosage: unk
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-08-03
    End date: 2012-08-08

Other drugs received by patient: Vancomycin; Zosyn; Micafungin; Voriconazole; Tacrolimus; Oxycodone HCL; Antibiotics; Methotrexate; Azithromycin; Neupogen; Coreg



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female, weighing 25.0 kg (55.0 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Cardiac Failure, Respiratory Failure, Sepsis, Pleural Effusion, Hypertension, Fusarium Infection

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: 70 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: 254 mg, qd
    Start date: 2012-06-16
    End date: 2012-06-19

Thymoglobulin
    Dosage: 229.9 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Other drugs received by patient: Meropenem; Fentanyl Citrate; Cytarabine; Thiotepa; Melphalan Hydrochloride; Dilaudid; Busulfan



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-16

Patient: female

Reactions: Pyrexia, Pupils Unequal, Cerebral Ischaemia, Pleural Effusion, Brain Oedema, Intracranial Pressure Increased, Staphylococcal Bacteraemia, Pupil Fixed, Blood Pressure Systolic Decreased, Pupillary Reflex Impaired, Cerebral Artery Stenosis, Brain Stem Haemorrhage, Brain Herniation, Hyperreflexia, Ascites, Convulsion, Venoocclusive Disease, Bacteraemia, Respiratory Failure, Meningitis Bacterial, Mental Disorder, Acute Myeloid Leukaemia Recurrent

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clolar
    Dosage: 52 mg/m2, dose level 3
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-07-13
    End date: 2012-07-17

Cytarabine
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-07-12



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-16

Patient: female, weighing 25.2 kg (55.4 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Cardiac Failure, Respiratory Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: unk
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Melphalan Hydrochloride; Busulfan; Fentanyl; Thiotepa; Cytarabine; Dilaudid; Meropenem



Possible Clolar side effects in female

Reported by a physician from United States on 2012-08-13

Patient: female, weighing 25.2 kg (55.4 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Respiratory Failure, Cardiac Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: unk
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Meropenem; Melphalan Hydrochloride; Cytarabine; Busulfan; Dilaudid; Fentanyl; Thiotepa



Possible Clolar side effects in male

Reported by a physician from United States on 2012-04-24

Patient: male, weighing 90.0 kg (198.0 pounds)

Reactions: Cardio-Respiratory Arrest, Mouth Haemorrhage, Unresponsive To Stimuli, Febrile Neutropenia, Pleural Effusion, Pancytopenia, Pneumonitis

Adverse event resulted in: death

Drug(s) suspected as cause:
Clolar



Possible Clolar side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-17

Patient: male, weighing 116.6 kg (256.5 pounds)

Reactions: Renal Failure, Pneumonia, Neutropenic Colitis, Neutropenic Sepsis, Hypotension, Pleural Effusion, Mental Status Changes, Staphylococcal Bacteraemia, Pulseless Electrical Activity

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Busulfan
    Dosage: 249 mg, once
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-03-30
    End date: 2012-03-31

Busulfan
    Dosage: 390 mg, once
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-04-01
    End date: 2012-04-02

Clolar
    Dosage: 94 mg, once
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-03-29
    End date: 2012-04-02

Clolar
    Indication: Bone Marrow Conditioning Regimen



Possible Clolar side effects in male

Reported by a consumer/non-health professional from Australia on 2011-12-19

Patient: male

Reactions: Pleural Effusion, Febrile Neutropenia, Urinary Retention, Constipation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clolar
    Dosage: 20 mg/m2, qdx5 cycle 1
    Indication: Acute Leukaemia
    Start date: 2011-01-18
    End date: 2011-01-22

Clolar
    Dosage: 20 mg/m2, qdx5 cycle 3

Clolar
    Dosage: 20 mg/m2, qdx5 cycle 4
    End date: 2011-04-16

Clolar
    Dosage: 20 mg/m2, qdx5 cycle 2

Ondansetron
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

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