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Carboplatin (Carboplatin) - Death - Suspected Cause - Side Effect Reports

 
 



Index of reports > Death (558)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Carboplatin death. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 558   Next >>

Possible Carboplatin side effects in 29 year old female

Reported by a physician from Hungary on 2012-08-27

Patient: 29 year old female

Reactions: Histiocytosis Haematophagic, Cytomegalovirus Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin
    Dosage: 8 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Carboplatin
    Dosage: 2 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Cisplatin
    Dosage: 2 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Cytarabine
    Dosage: 2 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Dacarbazine
    Dosage: 8 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Dexamethasone Sodium Phosphate
    Dosage: 2 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Doxorubicin HCL
    Dosage: 8 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Doxorubicin HCL
    Dosage: unk
    Indication: Hodgkin's Disease

Etoposide
    Dosage: 2 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Etoposide
    Dosage: unk
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01

Gemcitabine Hydrochloride
    Dosage: unk
    Indication: Hodgkin's Disease
    Start date: 2007-01-01

Ifosfamide
    Dosage: unk
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01

Ifosfamide
    Dosage: 2 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Rituximab
    Dosage: unk
    Indication: Hodgkin's Disease
    Start date: 2007-01-01

Vinblastine
    Dosage: 8 cycles
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Vinorelbine
    Dosage: unk
    Indication: Hodgkin's Disease
    Start date: 2007-01-01



Possible Carboplatin side effects in 58 year old male

Reported by a consumer/non-health professional from Argentina on 2012-08-24

Patient: 58 year old male

Reactions: Hepatotoxicity, Neoplasm Malignant, Sepsis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Start date: 2012-01-01

Yervoy
    Dosage: no of inf:2 infusion on 9feb12
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-02-09



Possible Carboplatin side effects in 29 year old female

Reported by a health professional (non-physician/pharmacist) from Hungary on 2012-08-24

Patient: 29 year old female

Reactions: Histiocytosis Haematophagic, Neoplasm Malignant, Cytomegalovirus Infection, Pancytopenia, Immunosuppression

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Carboplatin
    Indication: Hodgkin's Disease

Cisplatin
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Cytarabine
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Dacarbazine
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Doxorubicin Hydrochloride
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Etoposide
    Indication: Hodgkin's Disease

Gemcitabine Hydrochloride
    Indication: Hodgkin's Disease

Ifosfamide
    Indication: Hodgkin's Disease

Rituximab
    Indication: Hodgkin's Disease

Vinblastine Sulfate
    Indication: Hodgkin's Disease
    Start date: 2006-01-01

Vinorelbine
    Indication: Hodgkin's Disease

Other drugs received by patient: Dexamethasone



Possible Carboplatin side effects in male

Reported by a physician from France on 2012-08-24

Patient: male

Reactions: Dermatitis Acneiform, Renal Failure, Neoplasm Malignant, Dehydration, Purpura, Neutropenia, Thrombocytopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Carboplatin
    Dosage: 200 df, unknown/d
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-08-03

Erlotinib Hydrochloride
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer

Erlotinib Hydrochloride
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Start date: 2012-08-17

Pemetrexed Disodium
    Dosage: 200 df, unknown/d
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-08-03



Possible Carboplatin side effects in 29 year old female

Reported by a physician from Hungary on 2012-08-23

Patient: 29 year old female

Reactions: Histiocytosis Haematophagic, Pancytopenia, Cytomegalovirus Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Carboplatin
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Cisplatin
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Cytarabine
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Dacarbazine
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Dexamethasone
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Doxorubicin Hydrochloride
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Etoposide
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Etoposide
    Start date: 2007-01-01

Gemcitabine Hydrochloride
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01

Ifosfamide
    Start date: 2007-01-01

Ifosfamide
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Rituximab
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01

Vinblastine Sulfate
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Vinorelbine
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01



Possible Carboplatin side effects in 29 year old female

Reported by a physician from Hungary on 2012-08-23

Patient: 29 year old female

Reactions: Histiocytosis Haematophagic, Pancytopenia, Cytomegalovirus Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Carboplatin
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Cisplatin
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Cytarabine
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Dacarbazine
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Dexamethasone
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Doxorubicin Hydrochloride
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Etoposide
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Etoposide
    Start date: 2007-01-01

Gemcitabine Hydrochloride
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01

Ifosfamide
    Start date: 2007-01-01

Ifosfamide
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Rituximab
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01

Vinblastine Sulfate
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Vinorelbine
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01



Possible Carboplatin side effects in 63 year old male

Reported by a consumer/non-health professional from Germany on 2012-08-22

Patient: 63 year old male

Reactions: Circulatory Collapse

Adverse event resulted in: death

Drug(s) suspected as cause:
Carboplatin
    Dosage: recent dose:20apr12
    Indication: Head and Neck Cancer
    Start date: 2012-03-05
    End date: 2012-04-20

Cetuximab
    Dosage: 400mg/m2:05mar12-unk, 250mg/m2:unk-16apr12. recent dose:16apr12
    Indication: Head and Neck Cancer
    Start date: 2012-03-05

Fluorouracil
    Dosage: recent dose:16apr12
    Indication: Head and Neck Cancer
    Start date: 2012-03-05
    End date: 2012-04-20



Possible Carboplatin side effects in male

Reported by a physician from Hungary on 2012-08-22

Patient: male, weighing 74.0 kg (162.8 pounds)

Reactions: Pneumonia, Anaemia, Granulocytopenia, Neutropenia, Thrombocytopenia, Leukopenia, Infectious Pleural Effusion

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: frequency: 1x, form infusion;
    Indication: non-Small Cell Lung Cancer

Avastin
    Dosage: frequency as per protocol, last dose of prior to event on 25 january 2010. form infusion

Avastin
    Dosage: last dose prior to sae: 16 february 2010. last dose prior to leukopenia was 23 mar 2010

Avastin
    Dosage: last dose prior to sae: 16 february 2010,infusion, frequency: 1xdaily

Carboplatin
    Dosage: last dose prior to event on 25 january 2010.

Carboplatin
    Dosage: form: infusion;
    Indication: non-Small Cell Lung Cancer

Carboplatin
    Dosage: last dose prior to sae: 23 march 2010, frequency: 1xdaily

Carboplatin

Gemcitabine Hydrochloride
    Dosage: last dose prior to sae: 01 april 2010

Gemcitabine Hydrochloride

Gemcitabine Hydrochloride
    Dosage: freq: day 1 + 8 every 3 weeks

Gemcitabine Hydrochloride
    Dosage: last dose of iv gemcitabine prior to event on 25 january 2010.

Gemcitabine Hydrochloride
    Dosage: freq: day 1 + 8 every 3 weeks

Gemcitabine Hydrochloride
    Dosage: form infusion, on day 1 and day 8; frequency: 1xdaily;
    Indication: non-Small Cell Lung Cancer
    Start date: 2009-11-09
    End date: 2009-11-17

Gemcitabine Hydrochloride
    Dosage: frequency: 2xevery three week, form: infusion

Other drugs received by patient: Fluticasone Propionate / Salmeterol; Augmentin '500'; Kalium-R; Sinecod; Ondansetron; Bisoprolol Fumarate; Pegfilgrastim; Lidocaine; Ciprofloxacin Hydrochloride; Neupogen; Spiriva; Kalium-R; Eprex; Neorecormon; Hydromorphone HCL; Berodual; Fluticasone Propionate / Salmeterol; Neorecormon; Augmentin '500'; Kalium-R; Medrol; Medrol; Neupogen; Medrol; Bisoprolol Fumarate; Spiriva; Megesin; Megesin



Possible Carboplatin side effects in 29 year old female

Reported by a physician from Hungary on 2012-08-21

Patient: 29 year old female

Reactions: Histiocytosis Haematophagic, Cytomegalovirus Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Carboplatin
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Cisplatin
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Cytarabine
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Dacarbazine
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Dexamethasone
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Doxorubicin HCL
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Doxorubicin HCL

Etoposide
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Etoposide
    Start date: 2007-01-01

Gemcitabine Hydrochloride
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01

Ifosfamide
    Start date: 2007-01-01

Ifosfamide
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Rituximab
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01

Vinblastine Sulfate
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2006-01-01

Vinorelbine
    Indication: non-Hodgkin's Lymphoma Stage IV
    Start date: 2007-01-01



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Germany on 2012-08-20

Patient: 65 year old female, weighing 86.0 kg (189.2 pounds)

Reactions: Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: dose reduced
    Start date: 2010-06-15
    End date: 2010-07-22

Carboplatin
    Dosage: form: vialsdose level: 5 auc
    Start date: 2010-05-04

Docetaxel
    Dosage: dose: 60mg/m2, form:vials
    Start date: 2010-05-04

Docetaxel
    Dosage: dose reduced, form:vials
    Start date: 2010-06-15
    End date: 2010-07-22

Trastuzumab
    Dosage: dose level: 6mg/kgform: vials
    Start date: 2010-05-04
    End date: 2010-07-22

Other drugs received by patient: Metoclopramide; Bisoprolol Fumarate; Ondansetron; Dexamethasone; Emend; Loperamide



Possible Carboplatin side effects in 59 year old male

Reported by a physician from United States on 2012-08-20

Patient: 59 year old male, weighing 92.1 kg (202.6 pounds)

Reactions: Oesophageal Fistula, Post Procedural Haemorrhage

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: on day 1 over 30-90 minutes, last dose prior to the event: 23/may/2012
    Indication: Head and Neck Cancer
    Start date: 2012-05-23

Carboplatin
    Dosage: auc 6 over 30 minutes on day 1, last dose prior to the event: 12/jul/2012
    Indication: Head and Neck Cancer
    Start date: 2012-05-23

Docetaxel
    Dosage: over 1 hour on day 1, last dose prior to the event: 12/jul/2012
    Indication: Head and Neck Cancer
    Start date: 2012-05-23



Possible Carboplatin side effects in male

Reported by a physician from Japan on 2012-08-20

Patient: male

Reactions: Pneumonia Aspiration, Haemoptysis

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Avastin
    Indication: Lung Adenocarcinoma

Carboplatin
    Indication: Lung Adenocarcinoma

Pemetrexed
    Indication: Lung Adenocarcinoma



Possible Carboplatin side effects in 22 year old male

Reported by a consumer/non-health professional from United States on 2012-08-17

Patient: 22 year old male, weighing 83.0 kg (182.6 pounds)

Reactions: Neoplasm Malignant

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin

Carboplatin

Etoposide

Sprycel

Other drugs received by patient: Medrol; Phenergan HCL; Ativan; Reglan



Possible Carboplatin side effects in 69 year old female

Reported by a physician from Belgium on 2012-08-17

Patient: 69 year old female

Reactions: Acute Myeloid Leukaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 700 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-19

Carboplatin
    Dosage: 720 mg, unk
    Start date: 2006-11-30

Carboplatin
    Dosage: 830 mg, unk
    Start date: 2006-11-09

Etoposide
    Dosage: 190 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-18

Etoposide
    Dosage: 1600 mg, unk
    Start date: 2007-01-16

Filgrastim
    Dosage: 6000 mug, qd (day 6 to day 13)
    Indication: Diffuse Large B-Cell Lymphoma

Ifosfamide
    Dosage: 9600 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-19

Ifosfamide
    Dosage: 9400 mg, unk
    Start date: 2006-11-09

Ifosfamide
    Dosage: 9500 mg, unk
    Start date: 2006-11-30

Rituximab
    Dosage: 720 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-18

Rituximab
    Dosage: 710 mg, unk
    Start date: 2006-11-08

Rituximab
    Dosage: 710 mg, unk
    Start date: 2006-11-29

Other drugs received by patient: Melphalan Hydrochloride; Cytarabine; Carmustine



Possible Carboplatin side effects in female

Reported by a individual with unspecified qualification from Belgium on 2012-08-15

Patient: female, weighing 94.9 kg (208.8 pounds)

Reactions: Acute Myeloid Leukaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Diffuse Large B-Cell Lymphoma Stage IV
    Start date: 2006-10-19

Carboplatin
    Start date: 2006-11-09

Carboplatin
    Start date: 2006-11-30

Etoposide
    Start date: 2006-11-08

Etoposide
    Indication: Diffuse Large B-Cell Lymphoma Stage IV
    Start date: 2006-10-18

Etoposide
    Start date: 2006-10-19

Etoposide
    Start date: 2006-10-20

Etoposide
    Start date: 2006-11-29

Etoposide
    Start date: 2006-11-30

Etoposide
    Start date: 2006-11-09

Etoposide
    Start date: 2006-11-10

Etoposide
    Start date: 2006-12-01

Ifosfamide
    Indication: Diffuse Large B-Cell Lymphoma Stage IV
    Start date: 2006-10-19

Ifosfamide
    Start date: 2006-11-09

Ifosfamide
    Start date: 2006-11-30

Pegfilgrastim
    Dosage: 6000 ug/day
    Indication: Diffuse Large B-Cell Lymphoma Stage IV

Rituximab
    Start date: 2006-11-08

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma Stage IV
    Start date: 2006-10-16

Rituximab
    Start date: 2006-10-18

Rituximab
    Start date: 2006-11-29

Other drugs received by patient: Cordarone; Combivent; Zantac; Zantac; Cordarone; Combivent



Possible Carboplatin side effects in 29 year old female

Reported by a health professional (non-physician/pharmacist) from Hungary on 2012-08-14

Patient: 29 year old female

Reactions: Histiocytosis Haematophagic, Oophoritis, Pancytopenia, Cytomegalovirus Infection, Pyrexia, Pneumonia Cytomegaloviral

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Bleomycin Sulfate
    Indication: Hodgkin's Disease

Carboplatin
    Indication: Hodgkin's Disease

Cisplatin
    Indication: Hodgkin's Disease

Cytarabine
    Indication: Hodgkin's Disease

Dacarbazine
    Indication: Hodgkin's Disease

Dexamethasone
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Gemcitabine Hydrochloride
    Indication: Hodgkin's Disease

Ifosfamide
    Indication: Hodgkin's Disease

Rituximab
    Indication: Hodgkin's Disease

Vinblastine Sulfate
    Indication: Hodgkin's Disease

Vinorelbine
    Indication: Hodgkin's Disease

Other drugs received by patient: Radiotherapy



Possible Carboplatin side effects in 29 year old female

Reported by a health professional (non-physician/pharmacist) from Hungary on 2012-08-14

Patient: 29 year old female

Reactions: Histiocytosis Haematophagic, Oophoritis, Cytomegalovirus Infection, Pancytopenia, Pyrexia, Pneumonia Cytomegaloviral

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Bleomycin Sulfate
    Indication: Hodgkin's Disease

Carboplatin
    Indication: Hodgkin's Disease

Cisplatin
    Indication: Hodgkin's Disease

Cytarabine
    Indication: Hodgkin's Disease

Dacarbazine
    Indication: Hodgkin's Disease

Dexamethasone
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Gemcitabine Hydrochloride
    Indication: Hodgkin's Disease

Ifosfamide
    Indication: Hodgkin's Disease

Rituximab
    Indication: Hodgkin's Disease

Vinblastine Sulfate
    Indication: Hodgkin's Disease

Vinorelbine
    Indication: Hodgkin's Disease

Other drugs received by patient: Radiotherapy



Possible Carboplatin side effects in 71 year old male

Reported by a physician from Japan on 2012-08-14

Patient: 71 year old male, weighing 45.0 kg (99.0 pounds)

Reactions: Haemoglobin Decreased, Diarrhoea, Febrile Neutropenia, Gastroenteritis Staphylococcal, Thrombocytopenia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Carboplatin
    Dosage: 220 mg, single
    Indication: Small Cell Lung Cancer Stage Unspecified
    Start date: 2011-12-21
    End date: 2011-12-21

Carboplatin
    Dosage: 210 mg, single
    Start date: 2012-02-28
    End date: 2012-02-28

Carboplatin
    Dosage: 220 mg, single
    Start date: 2012-01-20
    End date: 2012-01-20

Irinotecan Hydrochloride
    Dosage: 70 mg, single
    Indication: Small Cell Lung Cancer Stage Unspecified
    Start date: 2011-12-21
    End date: 2011-12-21

Irinotecan Hydrochloride
    Dosage: 60 mg, single
    Start date: 2012-03-06
    End date: 2012-03-06

Irinotecan Hydrochloride
    Dosage: 60 mg, single
    Start date: 2012-02-28
    End date: 2012-02-28

Irinotecan Hydrochloride
    Dosage: 70 mg, single
    Start date: 2011-12-28
    End date: 2011-12-28

Irinotecan Hydrochloride
    Dosage: 70 mg, single
    Start date: 2012-01-20
    End date: 2012-01-20

Irinotecan Hydrochloride
    Dosage: 70 mg, single
    Start date: 2012-01-27
    End date: 2012-01-27

Other drugs received by patient: NEU-UP; Ambisome; Lansoprazole; Decadron Phosphate; Vancomycin Hydrochloride; Zyvox; Kremezin; Platelets, Human Blood; Allopurinol; Maxipime; Loperamide Hydrochloride; Itraconazole; Targocid; Meropenem; BIO Three; Gran; Medrol



Possible Carboplatin side effects in 52 year old male

Reported by a physician from Germany on 2012-08-14

Patient: 52 year old male, weighing 105.2 kg (231.4 pounds)

Reactions: Gastric Ulcer Haemorrhage

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: last dose administered 1575 mg on 05/june/2012
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-24

Carboplatin
    Dosage: last dose administered 432 mg on 05/june/2012
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-24

Megf0444a (Anti-Egfl7)
    Dosage: last dose - 05/june/2012, 605 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-24

Paclitaxel
    Dosage: last dose administered 432 mg on 05/june/2012
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-24

Other drugs received by patient: Ondansetron; Dexamethasone; Erythrocyte Transfusions; Diclofenac; ACC Long; Ibuprofen; Clemastine Fumarate; Oxazepam; Fresh Frozen Plasma; Omeprazole; Ranitidine; Zopiclon



Possible Carboplatin side effects in female

Reported by a physician from Belgium on 2012-08-13

Patient: female

Reactions: Acute Myeloid Leukaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: cycle 1 day 2
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-19

Carboplatin
    Dosage: cycle 2 day 2
    Start date: 2006-11-09

Carboplatin
    Dosage: cycle 3 day 2
    Start date: 2006-11-30

Etoposide
    Dosage: cycle 1 day 3

Etoposide
    Start date: 2007-01-16

Etoposide
    Dosage: cycle 1 day 1
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-16

Etoposide
    Dosage: cycle 1 day 2

Filgrastim
    Dosage: dose 6000 ug/day from d6 to d13 of cycle 1,2 and 3
    Indication: Diffuse Large B-Cell Lymphoma

Ifosfamide
    Dosage: cycle 3 day 2
    Start date: 2006-11-30

Ifosfamide
    Dosage: cycle 1 day 2
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-02-19

Ifosfamide
    Dosage: cycle 2 day 2
    Start date: 2006-11-09

Mabthera
    Dosage: cycle 1 day 2

Mabthera
    Dosage: cycle 3 day 1
    Start date: 2006-11-29

Mabthera
    Dosage: cycle 2 day 1
    Start date: 2006-11-08

Mabthera
    Dosage: cycle 1 day 1
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-16

Other drugs received by patient: Melphalan Hydrochloride; Cytarabine; Carmustine



Possible Carboplatin side effects in 58 year old female

Reported by a physician from United States on 2012-08-13

Patient: 58 year old female, weighing 79.0 kg (173.8 pounds)

Reactions: Obstruction Gastric, Vomiting, Hyperkalaemia, Nausea, Supraventricular Tachycardia, Febrile Neutropenia, Aspiration, Sepsis, Abdominal Distension, Cardiac Arrest

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: last dose administered on 12/may/2011
    Indication: Endometrial Cancer
    Start date: 2012-05-12

Carboplatin
    Dosage: auc=6; last dose administered on:12/may/2011
    Indication: Endometrial Cancer
    Start date: 2011-05-12

Ixabepilone
    Dosage: last dose administerd:12/may/2011
    Indication: Endometrial Cancer
    Start date: 2012-05-12

Other drugs received by patient: Protonix; Norco; Compazine; Synthroid; Ventolin; Lovenox



Possible Carboplatin side effects in 65 year old male

Reported by a health professional (non-physician/pharmacist) from Switzerland on 2012-08-10

Patient: 65 year old male

Reactions: Multi-Organ Failure, Gastrointestinal Haemorrhage, Dermatitis, Interstitial Lung Disease, Acute Respiratory Distress Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Pharyngeal Cancer Stage Unspecified

Cetuximab
    Dosage: loading dose:600mg then 400mg
    Indication: Pharyngeal Cancer Stage Unspecified

Taxol
    Indication: Pharyngeal Cancer Stage Unspecified



Possible Carboplatin side effects in female

Reported by a physician from France on 2012-08-10

Patient: female, weighing 70.0 kg (154.0 pounds)

Reactions: Musculoskeletal Chest Pain, Respiratory Distress, Bronchial Obstruction

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-01-31
    End date: 2011-04-04

Carboplatin
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-01-31
    End date: 2011-04-04

Pemetrexed Disodium
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-05-23
    End date: 2011-08-04



Possible Carboplatin side effects in 69 year old female

Reported by a physician from Belgium on 2012-08-10

Patient: 69 year old female

Reactions: Acute Myeloid Leukaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 830 mg, unk
    Start date: 2006-11-09

Carboplatin
    Dosage: 720 mg, unk
    Start date: 2006-11-30

Carboplatin
    Dosage: 700 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-19

Etoposide
    Dosage: 190 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-18

Etoposide
    Dosage: 1600 mg, unk
    Start date: 2007-01-16

Filgrastim
    Dosage: 6000 mug, qd (day 6 to day 13)
    Indication: Diffuse Large B-Cell Lymphoma

Ifosfamide
    Dosage: 9600 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-02-19

Ifosfamide
    Dosage: 9400 mg, unk
    Start date: 2006-11-09

Ifosfamide
    Dosage: 9500 mg, unk
    Start date: 2006-11-30

Rituximab
    Dosage: 710 mg, unk
    Start date: 2006-11-29

Rituximab
    Dosage: 710 mg, unk
    Start date: 2006-11-08

Rituximab
    Dosage: 720 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-18

Other drugs received by patient: Cytarabine; Carmustine; Melphalan Hydrochloride



Possible Carboplatin side effects in 58 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-10

Patient: 58 year old female, weighing 79.0 kg (173.8 pounds)

Reactions: Obstruction Gastric, Vomiting, Hyperkalaemia, Nausea, Supraventricular Tachycardia, Febrile Neutropenia, Aspiration, Sepsis, Abdominal Distension, Cardiac Arrest

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Dosage: last administered 12may2011
    Indication: Endometrial Cancer
    Start date: 2011-05-12

Carboplatin
    Dosage: last administered 12may2011
    Indication: Endometrial Cancer
    Start date: 2011-05-12

Ixabepilone
    Dosage: last administered 12may2011
    Indication: Endometrial Cancer
    Start date: 2011-05-12

Other drugs received by patient: Norco; Compazine; Synthroid; Ventolin; Protonix; Lovenox



Possible Carboplatin side effects in 69 year old female

Reported by a physician from Belgium on 2012-08-10

Patient: 69 year old female

Reactions: Acute Myeloid Leukaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 830 mg, unk
    Start date: 2006-11-09

Carboplatin
    Dosage: 700 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-19

Carboplatin
    Dosage: 720 mg, unk
    Start date: 2006-11-30

Etoposide
    Dosage: 190 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-18

Etoposide
    Dosage: 1600 mg, unk
    Start date: 2007-01-16

Filgrastim
    Dosage: 6000 mug, qd (day 6 to day 13)
    Indication: Diffuse Large B-Cell Lymphoma

Ifosfamide
    Dosage: 9600 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-02-19

Ifosfamide
    Dosage: 9400 mg, unk
    Start date: 2006-11-09

Ifosfamide
    Dosage: 9500 mg, unk
    Start date: 2006-11-30

Rituximab
    Dosage: 720 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-18

Rituximab
    Dosage: 710 mg, unk
    Start date: 2006-11-08

Rituximab
    Dosage: 710 mg, unk
    Start date: 2006-11-29

Other drugs received by patient: Carmustine; Cytarabine; Melphalan Hydrochloride



Possible Carboplatin side effects in 52 year old male

Reported by a physician from Germany on 2012-08-09

Patient: 52 year old male, weighing 105.2 kg (231.4 pounds)

Reactions: Gastric Ulcer Haemorrhage

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: last dose administered 1575 mg on 05/june/2012
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-24

Carboplatin
    Dosage: last dose administered 432 mg on 05/june/2012
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-24

Megf0444a (Anti-Egfl7)
    Dosage: last dose - 05/june/2012, 605 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-24

Paclitaxel
    Dosage: last dose administered 432 mg on 05/june/2012
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-24

Other drugs received by patient: Diclofenac; Omeprazole; Ibuprofen



Possible Carboplatin side effects in female

Reported by a physician from United States on 2012-08-07

Patient: female, weighing 69.9 kg (153.8 pounds)

Reactions: Urinary Tract Infection, Bacterial Sepsis, Abscess, Peritonitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 792 mg
    End date: 2011-08-10

Herceptin
    Dosage: 140 mg
    End date: 2011-08-10

Taxotere
    Dosage: 130 mg
    End date: 2011-08-10



Possible Carboplatin side effects in 69 year old female

Reported by a physician from Belgium on 2012-08-06

Patient: 69 year old female

Reactions: Acute Myeloid Leukaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 700 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-19

Carboplatin
    Dosage: 720 mg, unk
    Start date: 2006-11-30

Carboplatin
    Dosage: 830 mg, unk
    Start date: 2006-11-09

Etoposide
    Dosage: 190 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-18

Etoposide
    Dosage: 1600 mg, unk
    Start date: 2007-01-16

Ifosfamide
    Dosage: 9500 mg, unk
    Start date: 2006-11-30

Ifosfamide
    Dosage: 9600 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-02-19

Ifosfamide
    Dosage: 9400 mg, unk
    Start date: 2006-11-09

Pegfilgrastim
    Dosage: 6000 mug, qd (day 6 to day 13)
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: 720 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2006-10-18

Rituximab
    Dosage: 710 mg, unk
    Start date: 2006-11-29

Rituximab
    Dosage: 710 mg, unk
    Start date: 2006-11-08

Other drugs received by patient: Cytarabine; Melphalan Hydrochloride; Carmustine



Possible Carboplatin side effects in female

Reported by a physician from China on 2012-08-06

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: Death, Cardiac Failure

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: most recent dose prior to the event: 21/mar/2012, 840 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-01-05

Carboplatin
    Dosage: most recent dose prior to event: 21/mar/2012, 739 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-01-05

Paclitaxel
    Dosage: most recent dose prior to event: 21/mar/2012, 265 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-01-05



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