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Carboplatin (Carboplatin) - Sepsis - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Sepsis (91)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Carboplatin where reactions include sepsis. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 91   Next >>

Possible Carboplatin side effects in 58 year old male

Reported by a consumer/non-health professional from Argentina on 2012-08-24

Patient: 58 year old male

Reactions: Hepatotoxicity, Neoplasm Malignant, Sepsis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Yervoy
    Dosage: no of inf:2 infusion on 9feb12
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-02-09

Carboplatin
    Start date: 2012-01-01



Possible Carboplatin side effects in 58 year old female

Reported by a physician from United States on 2012-08-13

Patient: 58 year old female, weighing 79.0 kg (173.8 pounds)

Reactions: Obstruction Gastric, Vomiting, Hyperkalaemia, Nausea, Supraventricular Tachycardia, Febrile Neutropenia, Aspiration, Sepsis, Abdominal Distension, Cardiac Arrest

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ixabepilone
    Dosage: last dose administerd:12/may/2011
    Indication: Endometrial Cancer
    Start date: 2012-05-12

Avastin
    Dosage: last dose administered on 12/may/2011
    Indication: Endometrial Cancer
    Start date: 2012-05-12

Carboplatin
    Dosage: auc=6; last dose administered on:12/may/2011
    Indication: Endometrial Cancer
    Start date: 2011-05-12

Other drugs received by patient: Protonix; Norco; Compazine; Synthroid; Ventolin; Lovenox



Possible Carboplatin side effects in 58 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-10

Patient: 58 year old female, weighing 79.0 kg (173.8 pounds)

Reactions: Obstruction Gastric, Vomiting, Hyperkalaemia, Nausea, Supraventricular Tachycardia, Febrile Neutropenia, Aspiration, Sepsis, Abdominal Distension, Cardiac Arrest

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ixabepilone
    Dosage: last administered 12may2011
    Indication: Endometrial Cancer
    Start date: 2011-05-12

Bevacizumab
    Dosage: last administered 12may2011
    Indication: Endometrial Cancer
    Start date: 2011-05-12

Carboplatin
    Dosage: last administered 12may2011
    Indication: Endometrial Cancer
    Start date: 2011-05-12

Other drugs received by patient: Norco; Compazine; Synthroid; Ventolin; Protonix; Lovenox



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Germany on 2012-07-23

Patient: 65 year old female, weighing 46.4 kg (102.1 pounds)

Reactions: Weight Decreased, Fistula, Nausea, Anaemia, General Physical Health Deterioration, Fatigue, Sepsis, Decreased Appetite, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Ovarian Cancer
    Start date: 2012-03-21
    End date: 2012-04-18

Carboplatin
    Dosage: auc 5,
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Paclitaxel
    Dosage: last dose:15/may/2012
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Avastin
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Carboplatin
    Dosage: auc 5, last dose:15/may/2012
    End date: 2012-06-10

Paclitaxel
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Other drugs received by patient: Novalgin; Pantoprazole; Zolpidem



Possible Carboplatin side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-17

Patient: 76 year old male, weighing 70.0 kg (154.0 pounds)

Reactions: Hypotension, Disseminated Intravascular Coagulation, Headache, Malaise, Sepsis, Neutropenia, Cardiac Arrest, Thrombocytopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Carboplatin
    Dosage: dose unit: unknown
    Indication: Small Cell Lung Cancer Stage Unspecified
    Start date: 2010-10-04
    End date: 2010-10-04

Etoposide
    Dosage: dose unit: unknown
    Indication: Small Cell Lung Cancer Stage Unspecified
    Start date: 2010-10-04
    End date: 2010-10-06

Other drugs received by patient: Aldactone; Urief; Warfarin Sodium; Alendronate Sodium; Spiriva; Magnesium Oxide; Theophylline; Ambroxol Hydrochloride; Enalapril Maleate; Seltepnon; Vasolator; Sotalol Hydrochloride



Possible Carboplatin side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Greece on 2012-07-16

Patient: 65 year old female

Reactions: Confusional State, Pneumonia, Dyspnoea, Hypersensitivity, Wheezing, Hypotension, Pyrexia, Respiratory Failure, Sepsis

Adverse event resulted in: death

Drug(s) suspected as cause:
Carboplatin



Possible Carboplatin side effects in 71 year old male

Reported by a physician from Greece on 2012-07-11

Patient: 71 year old male, weighing 69.0 kg (151.8 pounds)

Reactions: Abdominal Pain, Diarrhoea, Sepsis, Tachypnoea, Febrile Neutropenia, Acute Respiratory Failure

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Xeloda
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-25

Avastin
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-25

Carboplatin
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-25

Other drugs received by patient: Lipidil; Indapamide; Exforge; Kerlone



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Germany on 2012-06-28

Patient: 65 year old female, weighing 46.4 kg (102.1 pounds)

Reactions: Weight Decreased, Fistula, Fatigue, Nausea, Sepsis, Anaemia, General Physical Health Deterioration, Decreased Appetite, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Ovarian Cancer
    Start date: 2012-03-21
    End date: 2012-04-18

Carboplatin
    Dosage: auc 5,
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Paclitaxel
    Dosage: last dose:15/may/2012
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Carboplatin
    Dosage: auc 5, last dose:15/may/2012
    End date: 2012-06-10

Paclitaxel
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Avastin
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Other drugs received by patient: Pantoprazole; Zolpidem; Novalgin



Possible Carboplatin side effects in 16 month old female

Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-06-26

Patient: 16 month old female

Reactions: Sepsis

Adverse event resulted in: death

Drug(s) suspected as cause:
Etoposide
    Dosage: 2.5 mg/kg once daily for 5 consecutive days from day 0 (ceiv regimen)

Cisplatin
    Dosage: 3 mg/kg, once daily on day 0 (cecv regimen)
    Indication: Brain Neoplasm Malignant

Ifosfamide
    Dosage: 50 mg/kg daily for 5 consecutive days from day 0 (ceiv regimen)
    Indication: Brain Neoplasm Malignant

Vincristine
    Dosage: 0.05 mg/kg, 1x/day, day 0 and 7
    Indication: Brain Neoplasm Malignant

Etoposide
    Dosage: 2.5 mg/kg once daily on days 0, 1, and 2 (cecv regimen)
    Indication: Brain Neoplasm Malignant

Carboplatin
    Dosage: 10 mg/kg daily on days 0
    Indication: Brain Neoplasm Malignant

Cyclophosphamide
    Dosage: 50 mg/kg once daily on day 1 and 2 (cecv regimen)
    Indication: Brain Neoplasm Malignant



Possible Carboplatin side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-26

Patient:

Reactions: Sepsis

Adverse event resulted in: death

Drug(s) suspected as cause:
Bevacizumab(bevacizumab)
    Dosage: 15 mg/kg (day 1 of 21 day cycle),intravenous
    Indication: non-Small Cell Lung Cancer

Carboplatin
    Dosage: area under the concentration time curve=5 (day 1 of 21 day cycle), intravenous
    Indication: non-Small Cell Lung Cancer

Pemetrexed
    Dosage: 500 mg/m2 (day 1 of 21 day cycle), intravenous
    Indication: non-Small Cell Lung Cancer



Possible Carboplatin side effects in 16 month old female

Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-06-25

Patient: 16 month old female

Reactions: Sepsis

Adverse event resulted in: death

Drug(s) suspected as cause:
Etoposide
    Dosage: 2.5 mg/kg once daily on days 0, 1, and 2 (cecv regimen)
    Indication: Brain Neoplasm Malignant

Cisplatin
    Dosage: 3 mg/kg, once daily on day 0 (cecv regimen)
    Indication: Brain Neoplasm Malignant

Etoposide
    Dosage: 2.5 mg/kg once daily for 5 consecutive days from day 0 (ceiv regimen)

Carboplatin
    Dosage: 10 mg/kg daily on days 0
    Indication: Brain Neoplasm Malignant

Cyclophosphamide
    Dosage: 50 mg/kg once daily on day 1 and 2 (cecv regimen)
    Indication: Brain Neoplasm Malignant

Ifosfamide
    Dosage: 50 mg/kg daily for 5 consecutive days from day 0 (ceiv regimen)
    Indication: Brain Neoplasm Malignant

Vincristine
    Dosage: 0.05 mg/kg, 1x/day, day 0 and 7
    Indication: Brain Neoplasm Malignant



Possible Carboplatin side effects in 78 year old female

Reported by a individual with unspecified qualification from United States on 2012-06-25

Patient: 78 year old female, weighing 55.5 kg (122.1 pounds)

Reactions: Sepsis, Hypotension, Dehydration, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Docetaxel
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-26

Avastin
    Dosage: over 30 to 90 minutes
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-26

Carboplatin
    Dosage: auc 5 over 30 mins
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-26

Other drugs received by patient: Dexamethasone; Lipitor; Reglan; Zofran; Atenolol; Lisinopril



Possible Carboplatin side effects in female

Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-06-22

Patient: female

Reactions: Wound, Streptococcal Infection, Fall, Thermal Burn, Accident, Escherichia Test Positive, Pseudomonas Test Positive, Limb Injury, Impaired Healing, Sepsis, Wound Necrosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 350 mg milligram(s), intravenous (not otherwise specified)
    Indication: non-Small Cell Lung Cancer

Avastin
    Dosage: 400 mg millgram(s), intravenous (not otherwise specified)
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-03-07
    End date: 2012-03-07

Vinorelbine
    Dosage: 80 mg milligram(s), oral
    Indication: non-Small Cell Lung Cancer

Other drugs received by patient: Emperal; Prednisolon Nausea (Nausea) / 00016201 /



Possible Carboplatin side effects in female

Reported by a physician from Denmark on 2012-06-22

Patient: female

Reactions: Impaired Healing, Wound, Sepsis, Thermal Burn, Streptococcal Infection, Fall, Wound Necrosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vinorelbine Tartrate
    Dosage: 80 mg, unk
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-03-07

Carboplatin
    Dosage: 350 mg, unk
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-03-07

Avastin
    Dosage: 400 mg, unk
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-03-07
    End date: 2012-03-07

Other drugs received by patient: Prednisolone; Emperal



Possible Carboplatin side effects in

Reported by a consumer/non-health professional from Germany on 2012-06-21

Patient:

Reactions: Sepsis, Progressive Multifocal Leukoencephalopathy, Meningitis Tuberculous

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Neupogen
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Rituxan
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Cyclophosphamide
    Dosage: 2000 mg/m2, unk
    Indication: Product Used FOR Unknown Indication

Carboplatin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Etoposide
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Zevalin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Prednisone TAB
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Busulfan
    Dosage: 12 mg/kg, unk
    Indication: Product Used FOR Unknown Indication

Fludara
    Dosage: 250 mg/m2, unk
    Indication: Product Used FOR Unknown Indication

Doxorubicin Hydrochloride
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Ifosfamide
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Vincristine Sulfate
    Dosage: unk
    Indication: Product Used FOR Unknown Indication



Possible Carboplatin side effects in female

Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-06-19

Patient: female

Reactions: Wound, Pseudomonas Infection, Thermal Burn, Fall, Streptococcal Infection, Impaired Healing, Sepsis, Escherichia Infection, Wound Necrosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 350 mg
    Indication: non-Small Cell Lung Cancer

Vinorelbine
    Dosage: 80 mg
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer

Avastin
    Dosage: 400 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-03-07
    End date: 2012-03-07

Other drugs received by patient: Emperal; Prednisolone



Possible Carboplatin side effects in female

Reported by a physician from United States on 2012-06-19

Patient: female, weighing 86.0 kg (189.2 pounds)

Reactions: Vomiting, Escherichia Test Positive, Fatigue, Nausea, Urinary Tract Infection, Sepsis, Enterococcus Test Positive, Culture Urine Positive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Taxol
    Dosage: 324 mg

Carboplatin
    Dosage: 536 mg



Possible Carboplatin side effects in male

Reported by a physician from United States on 2012-06-13

Patient: male, weighing 85.3 kg (187.7 pounds)

Reactions: Respiratory Failure, Sepsis, Thrombocytopenia, Renal Failure Acute, Leukopenia, Infectious Peritonitis

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 6 df, q21d
    Indication: non-Small Cell Lung Cancer
    Start date: 2009-09-04
    End date: 2009-09-04

Pemetrexed Disodium
    Dosage: 500 mg/m2, q21d
    Indication: non-Small Cell Lung Cancer
    Start date: 2009-09-04
    End date: 2009-09-04

Avastin
    Dosage: 15 mg/m2, q21d
    Indication: non-Small Cell Lung Cancer
    Start date: 2009-09-04
    End date: 2009-09-04

Other drugs received by patient: Folic Acid; Duragesic-100; Vitamin B-12; Megestrol Acetate; Dexamethasone; Nexium; Fluconazole; Norco



Possible Carboplatin side effects in

Reported by a consumer/non-health professional from Canada on 2012-06-13

Patient:

Reactions: Sepsis, Progressive Multifocal Leukoencephalopathy, Meningitis Tuberculous

Adverse event resulted in: death

Drug(s) suspected as cause:
Neupogen
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Rituxan
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Busulfan
    Dosage: 12 mg/kg, qd
    Indication: Product Used FOR Unknown Indication

Cisplatin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Cyclophosphamide
    Dosage: 2000 mg/m2, qd
    Indication: Product Used FOR Unknown Indication

Etoposide
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Ifosfamide
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Zevalin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Prednisone TAB
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Vincristine Sulfate
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Fludara
    Dosage: 250 mg/m2, qd
    Indication: Product Used FOR Unknown Indication

Doxorubicin Hydrochloride
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Carboplatin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication



Possible Carboplatin side effects in female

Reported by a physician from United States on 2012-06-07

Patient: female, weighing 150.6 kg (331.2 pounds)

Reactions: Diarrhoea, Sepsis, Neutropenia, Thrombocytopenia, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Dosage: 10 mg/kg, qd
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-18
    End date: 2012-05-18

Afinitor
    Dosage: 5 mg, qw3 (m, w, f) all 4 weeks, repeat q28 days
    Administration route: Oral
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-21
    End date: 2012-05-25

Taxol
    Dosage: 80 mg/m2, unk
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-18
    End date: 2012-05-18

Carboplatin



Possible Carboplatin side effects in female

Reported by a physician from United States on 2012-06-07

Patient: female, weighing 150.6 kg (331.2 pounds)

Reactions: Diarrhoea, Sepsis, Neutropenia, Thrombocytopenia, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin

Taxol
    Dosage: 80 mg/m2, unk
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-18
    End date: 2012-05-18

Afinitor
    Dosage: 5 mg, qw3 (m, w, f) all 4 weeks, repeat q28 days
    Administration route: Oral
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-21
    End date: 2012-05-25

Bevacizumab
    Dosage: 10 mg/kg, qd
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-18
    End date: 2012-05-18



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Greece on 2012-06-06

Patient: 65 year old female

Reactions: Confusional State, Hypersensitivity, Hypotension, Toxicity To Various Agents, Respiratory Failure, Heart Rate Increased, Sepsis, Acute Respiratory Distress Syndrome, Infusion Related Reaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin



Possible Carboplatin side effects in 65 year old female

Reported by a physician from United States on 2012-06-06

Patient: 65 year old female, weighing 150.6 kg (331.2 pounds)

Reactions: Diarrhoea, Sepsis, Platelet Count Decreased, Neutrophil Count Decreased, Renal Failure Acute

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Everolimus
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-18

Carboplatin
    Dosage: 5 auc
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-18

Paclitaxel
    Dosage: last dose taken on 18/may/2012
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-18

Avastin
    Dosage: last dose taken 18/may/2012
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-18



Possible Carboplatin side effects in

Reported by a health professional (non-physician/pharmacist) from Belgium on 2012-06-02

Patient:

Reactions: Sepsis

Drug(s) suspected as cause:
Cetuximab

Fluorouracil

Cetuximab

Cisplatin

Carboplatin



Possible Carboplatin side effects in

Reported by a health professional (non-physician/pharmacist) from Belgium on 2012-06-02

Patient:

Reactions: Sepsis

Drug(s) suspected as cause:
Cisplatin

Carboplatin
    Dosage: dose unit:5

Fluorouracil



Possible Carboplatin side effects in

Reported by a health professional (non-physician/pharmacist) from Belgium on 2012-06-02

Patient:

Reactions: Sepsis

Drug(s) suspected as cause:
Cisplatin

Carboplatin
    Dosage: dose unit:5

Fluorouracil



Possible Carboplatin side effects in 53 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-01

Patient: 53 year old male, weighing 42.0 kg (92.4 pounds)

Reactions: White Blood Cell Count Decreased, Fall, Hypokalaemia, Tracheal Obstruction, Sepsis, Platelet Count Decreased, Hypoalbuminaemia, Neutrophil Count Decreased

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cetuximab
    Indication: Head and Neck Cancer
    Start date: 2012-03-07
    End date: 2012-03-07

Fluorouracil
    Dosage: last dose: 20apr12
    Indication: Head and Neck Cancer
    Start date: 2012-03-19
    End date: 2012-04-20

Carboplatin
    Dosage: 1df= 5auc last dose: 16apr12
    Indication: Head and Neck Cancer
    Start date: 2012-03-19
    End date: 2012-04-16

Other drugs received by patient: Oxycontin; Oxycodone Hydrochloride



Possible Carboplatin side effects in 57 year old female

Reported by a individual with unspecified qualification from United States on 2012-05-31

Patient: 57 year old female, weighing 51.5 kg (113.3 pounds)

Reactions: Hyperglycaemia, Sepsis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: iv over 90 min on day 1last dose prior to sae: 31/oct/2011).
    Indication: Oesophageal Adenocarcinoma
    Start date: 2011-10-03

Herceptin
    Dosage: iv over 30-60 min on days 8, 15, 22, 29 and 36

Herceptin
    Dosage: iv over 30-90 min on day 57

Paclitaxel
    Dosage: iv over 1 hr on days 1, 8, 15, 22, 29 and 36last dose prior to sae: 31/oct/2011).
    Indication: Oesophageal Adenocarcinoma
    Start date: 2011-10-03

Dexamethasone
    Indication: Product Used FOR Unknown Indication

Herceptin
    Dosage: iv over 30-90 min on day 1, maintenance therapy cycle 21

Carboplatin
    Dosage: iv over 1 hr on days 1, 8, 15, 22, 29 and 36last dose prior to sae: 31/oct/2011).
    Indication: Oesophageal Adenocarcinoma



Possible Carboplatin side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-31

Patient: female, weighing 57.6 kg (126.7 pounds)

Reactions: Diarrhoea, Disseminated Intravascular Coagulation, Sepsis, Febrile Neutropenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Docetaxel
    Dosage: temporarily interrupted
    Indication: Breast Cancer
    Start date: 2012-04-13
    End date: 2012-05-04

Herceptin
    Dosage: loading dose, temporarily interrupted
    Indication: Breast Cancer
    Start date: 2012-04-13
    End date: 2012-05-04

Carboplatin
    Indication: Breast Cancer
    Start date: 2012-04-13

Pertuzumab
    Dosage: loading dose
    Indication: Breast Cancer
    Start date: 2012-04-13

Other drugs received by patient: Zofran; Lovaza; Tylenol; Clindamycin



Possible Carboplatin side effects in male

Reported by a physician from United States on 2012-05-30

Patient: male, weighing 41.7 kg (91.7 pounds)

Reactions: White Blood Cell Count Decreased, Fall, Hypokalaemia, Tracheal Obstruction, Sepsis, Platelet Count Decreased, Hypoalbuminaemia, Neutrophil Count Decreased

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: auc 5, on day one
    Indication: Head and Neck Cancer
    Start date: 2012-03-19
    End date: 2012-04-16

Blinded Therapy
    Dosage: 400 mg/m2, on day one of cycle one only
    Indication: Head and Neck Cancer
    Start date: 2012-03-07
    End date: 2012-03-07

Fluorouracil
    Dosage: 1000 mg/m2 on days one to four
    Indication: Head and Neck Cancer
    Start date: 2012-03-19
    End date: 2012-04-20

Other drugs received by patient: Oxycodone; Oxycontin



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