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Carboplatin (Carboplatin) - Diarrhoea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Diarrhoea (237)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Carboplatin where reactions include diarrhoea. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 237   Next >>

Possible Carboplatin side effects in 65 year old female

Reported by a physician from Japan on 2012-08-24

Patient: 65 year old female, weighing 50.2 kg (110.6 pounds)

Reactions: Weight Decreased, Blood Bilirubin Increased, Cytomegalovirus Viraemia, Headache, Pyrexia, Interstitial Lung Disease, Oedema, Thrombocytopenia, Blood Sodium Decreased, Decreased Appetite, Vomiting, Stomatitis, Pneumonia, Alanine Aminotransferase Increased, Lymphopenia, Anaemia, Febrile Neutropenia, Rash, Blood Phosphorus Decreased, Blood Potassium Decreased, Diarrhoea, Alopecia, Aspartate Aminotransferase Increased, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Dosage: 30 mg/m2 x 1/4 week
    Start date: 2011-03-16

Adriamycin PFS
    Dosage: 40 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Carboplatin
    Dosage: 250 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 350 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Etoposide
    Dosage: 100 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Prednisolone
    Dosage: 1mg/kg x 1/2 week
    Start date: 2011-12-13
    End date: 2011-12-14

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Start date: 2011-03-16

Prednisolone
    Dosage: 2 mg/m2, 1x/day
    Administration route: Oral
    Start date: 2011-03-24

Ranimustine
    Dosage: 60 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-16

Vincristine Sulfate
    Dosage: 1 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Vindesine Sulfate
    Dosage: 2.4 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Other drugs received by patient: Mucosolvan; Lansoprazole; Sulfamethoxazole and Trimethoprim; Armodafinil; Zolpidem; Olopatadine HCL; Cefazolin Sodium; Ciprofloxacin HCL; Armodafinil; Zovirax; Magmitt; Alendronate Sodium



Possible Carboplatin side effects in female

Reported by a physician from Ireland on 2012-08-24

Patient: female, weighing 75.5 kg (166.1 pounds)

Reactions: Vomiting, Diarrhoea, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 790mg cyclic
    Indication: Breast Cancer
    Start date: 2012-08-09

Docetaxel
    Dosage: 75mgm2 cyclic
    Indication: Breast Cancer
    Start date: 2012-08-09

Lapatinib
    Dosage: 1000mg per day
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-08-09

Trastuzumab
    Dosage: 8mgk cyclic
    Indication: Breast Cancer
    Start date: 2012-08-09



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-22

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Avastin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Cisplatin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Pemetrexed Disodium
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Other drugs received by patient: Crestor; Potassium Chloride; Norfloxacin; Dolpasse



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-08-22

Patient: female, weighing 64.0 kg (140.8 pounds)

Reactions: Weight Decreased, Vomiting, Diarrhoea, General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Breast Cancer
    Start date: 2012-03-01
    End date: 2012-05-03

Carboplatin
    Dosage: auc 1
    Start date: 2012-05-10

Doxorubicin Hydrochloride
    Indication: Breast Cancer
    Start date: 2012-03-01

Lapatinib
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-03-01
    End date: 2012-05-03

Paclitaxel
    Indication: Breast Cancer
    Start date: 2012-03-01

Trastuzumab
    Indication: Breast Cancer
    Start date: 2012-03-01

Other drugs received by patient: Ranitidine HCL; Erythropoetin; Dexamethasone Sodium Phosphate; Lenograstim; Clemastin; Palonosetron



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-21

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration, Hypokalaemia

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Avastin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Cisplatin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Pemetrexed Disodium
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Other drugs received by patient: Crestor; Dolpasse; Potassium Chloride; Norfloxacin



Possible Carboplatin side effects in 50 year old female

Reported by a physician from United States on 2012-08-17

Patient: 50 year old female, weighing 72.6 kg (159.7 pounds)

Reactions: Vomiting, Diarrhoea, Urinary Tract Infection, Hyponatraemia, Asthenia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Blinded Therapy
    Start date: 2012-02-28

Blinded Therapy
    Start date: 2012-02-28

Carboplatin
    Start date: 2012-02-28

Docetaxel
    Start date: 2012-02-28

Trastuzumab
    Start date: 2012-02-28

Other drugs received by patient: Dexamethasone; Spironolactone; Loperamide; Atropine Sulfate / Diphenoxylate Hydrochloride; Simvastatin; Tramadol HCL; Magnesium Oxide; Meclizine; Prochlorperazine Maleate; Lorazepam; Citalopram Hydrobromide; Omeprazole; Ciprofloxacin HCL; Prednisolone Acetate



Possible Carboplatin side effects in 30 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16

Patient: 30 year old female, weighing 106.6 kg (234.5 pounds)

Reactions: Vomiting, Blood Potassium Decreased, Nausea, Diarrhoea, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: carboauc5
    Indication: Endometrial Cancer
    Start date: 2012-08-06
    End date: 2012-08-06

Paclitaxel
    Dosage: taxol 175mg/m2
    Indication: Endometrial Cancer
    Start date: 2012-08-07
    End date: 2012-08-10

Ridaforolimus
    Dosage: ridaforolimus 20mg po qd
    Administration route: Oral
    Indication: Endometrial Cancer
    Start date: 2012-08-07
    End date: 2012-08-10



Possible Carboplatin side effects in female

Reported by a physician from United States on 2012-08-15

Patient: female, weighing 57.6 kg (126.7 pounds)

Reactions: Abdominal Pain, Diarrhoea, Disseminated Intravascular Coagulation, Febrile Neutropenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: permanently discontinued
    End date: 2012-05-25

Carboplatin
    Dosage: temporarily discontinued
    Indication: Breast Cancer
    Start date: 2012-04-13
    End date: 2012-05-04

Docetaxel
    Dosage: permanently discontinued
    End date: 2012-05-25

Docetaxel
    Dosage: permanently discontinued
    Indication: Breast Cancer
    Start date: 2012-04-13
    End date: 2012-05-04

Herceptin
    Dosage: permanently discontinued
    End date: 2012-05-25

Herceptin
    Dosage: maintanance dose, temporarily interrupted
    End date: 2012-05-04

Herceptin
    Dosage: loading dose, permanently discontinued
    Indication: Breast Cancer
    Start date: 2012-04-13

Pertuzumab
    Dosage: loading dose
    Indication: Breast Cancer
    Start date: 2012-04-13
    End date: 2012-05-25

Other drugs received by patient: Clindamycin; Lovaza; Tylenol; Zofran



Possible Carboplatin side effects in 71 year old male

Reported by a physician from Japan on 2012-08-14

Patient: 71 year old male, weighing 45.0 kg (99.0 pounds)

Reactions: Haemoglobin Decreased, Diarrhoea, Febrile Neutropenia, Gastroenteritis Staphylococcal, Thrombocytopenia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Carboplatin
    Dosage: 220 mg, single
    Indication: Small Cell Lung Cancer Stage Unspecified
    Start date: 2011-12-21
    End date: 2011-12-21

Carboplatin
    Dosage: 210 mg, single
    Start date: 2012-02-28
    End date: 2012-02-28

Carboplatin
    Dosage: 220 mg, single
    Start date: 2012-01-20
    End date: 2012-01-20

Irinotecan Hydrochloride
    Dosage: 70 mg, single
    Indication: Small Cell Lung Cancer Stage Unspecified
    Start date: 2011-12-21
    End date: 2011-12-21

Irinotecan Hydrochloride
    Dosage: 60 mg, single
    Start date: 2012-03-06
    End date: 2012-03-06

Irinotecan Hydrochloride
    Dosage: 60 mg, single
    Start date: 2012-02-28
    End date: 2012-02-28

Irinotecan Hydrochloride
    Dosage: 70 mg, single
    Start date: 2011-12-28
    End date: 2011-12-28

Irinotecan Hydrochloride
    Dosage: 70 mg, single
    Start date: 2012-01-20
    End date: 2012-01-20

Irinotecan Hydrochloride
    Dosage: 70 mg, single
    Start date: 2012-01-27
    End date: 2012-01-27

Other drugs received by patient: NEU-UP; Ambisome; Lansoprazole; Decadron Phosphate; Vancomycin Hydrochloride; Zyvox; Kremezin; Platelets, Human Blood; Allopurinol; Maxipime; Loperamide Hydrochloride; Itraconazole; Targocid; Meropenem; BIO Three; Gran; Medrol



Possible Carboplatin side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: female, weighing 64.9 kg (142.8 pounds)

Reactions: Abdominal Pain, White Blood Cell Count Decreased, Vomiting, Gastrointestinal Haemorrhage, Nausea, Hyponatraemia, Hypokalaemia, Haemoglobin Decreased, Diarrhoea, Dehydration, Hypocalcaemia, Neutrophil Count Decreased, Blood Creatinine Increased, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 177 milligram
    Start date: 2012-07-18
    End date: 2012-07-25

Abraxane
    Dosage: 80 microgram/sq. meter
    Start date: 2012-08-01

Abraxane
    Dosage: 177 milligram
    Indication: Breast Cancer
    Start date: 2012-06-13

Carboplatin
    Dosage: 675 milligram
    Indication: Breast Cancer
    Start date: 2012-06-13

Carboplatin
    Dosage: 675 milligram
    Start date: 2012-07-18

Herceptin
    Dosage: 139 milligram
    Start date: 2012-07-18

Herceptin
    Dosage: 139 milligram
    Indication: Breast Cancer
    Start date: 2012-06-13

Other drugs received by patient: Dexamethasone; Gabapentin; Ativan; Motrin; Ativan; Vicodin; Ativan; Ativan



Possible Carboplatin side effects in 64 year old male

Reported by a physician from Italy on 2012-08-09

Patient: 64 year old male

Reactions: Abdominal Pain, Pancreatic Disorder, Diarrhoea, Hepatitis Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 400 ug/m2
    Indication: Lung Adenocarcinoma
    Start date: 2012-07-12
    End date: 2012-07-12

Gemcitabine
    Dosage: 1000 mg/m2, unk
    Indication: Lung Adenocarcinoma
    Start date: 2012-07-12
    End date: 2012-07-12

Other drugs received by patient: Oramorph SR; Tachidol; Beclomethasone Dipropionate; Medrol; Fragmin; Oxivent; Morphine Sulfate



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-08-07

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Diarrhoea, Pyrexia, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Breast Cancer
    Start date: 2012-02-07

Doxorubicin HCL
    Indication: Breast Cancer
    Start date: 2012-02-07

Lapatinib
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-02-07

Paclitaxel
    Indication: Breast Cancer
    Start date: 2012-02-07

Trastuzumab
    Indication: Breast Cancer
    Start date: 2012-02-07

Other drugs received by patient: Omeprazole



Possible Carboplatin side effects in female

Reported by a individual with unspecified qualification from United States on 2012-08-07

Patient: female, weighing 48.4 kg (106.4 pounds)

Reactions: Abdominal Pain, Vomiting, Nausea, Tachycardia, Small Intestinal Obstruction, Haemoglobin Decreased, Diarrhoea, Gastric Dilatation, Dehydration, Abdominal Distension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 332 mg
    End date: 2012-03-29

Taxol
    Dosage: 255 mg
    End date: 2012-03-29



Possible Carboplatin side effects in 75 year old female

Reported by a physician from United States on 2012-08-02

Patient: 75 year old female, weighing 49.7 kg (109.4 pounds)

Reactions: Activated Partial Thromboplastin Time Prolonged, Fatigue, Hypocalcaemia, White Blood Cell Count Decreased, Vomiting, Nausea, Hypotension, Renal Failure Chronic, Hypophosphataemia, Syncope, Respiratory Failure, Embolism, Diarrhoea, Aspartate Aminotransferase Increased, Hypermagnesaemia, Hypoalbuminaemia, Neutrophil Count Decreased, Enterocolitis Infectious

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: over 30-90 minutes on day 1 of cycles 2+. drug withdrawn.
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-31
    End date: 2012-02-21

Carboplatin
    Dosage: auc=6 iv on day 1 (cycle 1-6)
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-31

Paclitaxel
    Dosage: over 3 hours on day 1 (cycles, 1-6).
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-31



Possible Carboplatin side effects in 43 year old female

Reported by a physician from United States on 2012-07-30

Patient: 43 year old female, weighing 121.0 kg (266.2 pounds)

Reactions: Vomiting, Dyspnoea, Nausea, Anaemia, Hypokalaemia, Diarrhoea, Hypophagia, Dehydration, NO Therapeutic Response, Fluid Intake Reduced

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 100mg/m2 weekly iv
    Indication: Breast Cancer
    Start date: 2012-03-26
    End date: 2012-05-11

Carboplatin
    Dosage: auc 4.5 qwk iv
    Indication: Breast Cancer
    Start date: 2012-03-26
    End date: 2012-05-04

Other drugs received by patient: Depakote; Metformin Hydrochloride; Compazine; Crestor; Detrol; Hydrochlorothiazide; Prozac; Motrin



Possible Carboplatin side effects in 28 year old female

Reported by a physician from United States on 2012-07-26

Patient: 28 year old female

Reactions: Vomiting, Nausea, Diarrhoea, Bone Pain, Chills, Febrile Neutropenia, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Brentuximab Vedotin (Brentuximab Vedotin) Injection
    Dosage: 103 mg, qcycle, intravenous
    Indication: Hodgkin's Disease
    Start date: 2012-02-28
    End date: 2012-04-10

Carboplatin
    Dosage: 750 mg, qcycle
    Indication: Hodgkin's Disease
    Start date: 2012-04-18
    End date: 2012-05-11

Etoposide
    Dosage: 400 mg, cycle
    Indication: Hodgkin's Disease
    Start date: 2012-04-18
    End date: 2012-05-11

Ifosfamide
    Dosage: 10000 mg, qcycle
    Indication: Hodgkin's Disease
    Start date: 2012-04-18
    End date: 2012-05-11



Possible Carboplatin side effects in female

Reported by a physician from United States on 2012-07-26

Patient: female, weighing 100.0 kg (220.0 pounds)

Reactions: Hypophosphataemia, Vomiting, Diarrhoea, Nausea, Dehydration, Hypomagnesaemia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-07-26

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Diarrhoea, Pyrexia, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Breast Cancer
    Start date: 2012-02-07

Doxorubicin HCL
    Indication: Breast Cancer
    Start date: 2012-02-07

Lapatinib
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-02-07

Paclitaxel
    Indication: Breast Cancer
    Start date: 2012-02-07

Trastuzumab
    Indication: Breast Cancer
    Start date: 2012-02-07

Other drugs received by patient: Omeprazole



Possible Carboplatin side effects in 75 year old female

Reported by a physician from United States on 2012-07-24

Patient: 75 year old female, weighing 51.4 kg (113.0 pounds)

Reactions: White Blood Cell Count Decreased, Hypotension, Hypophosphataemia, Activated Partial Thromboplastin Time Prolonged, Fatigue, Diarrhoea, Embolism, Hypermagnesaemia, Hypocalcaemia, Hypoalbuminaemia, Neutrophil Count Decreased, Enterocolitis Infectious

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: over 30-90 minutres on day 1 of cycles 2+
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-31

Carboplatin
    Dosage: auc=6 iv on day 1 (cycle 1-6)
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-31

Paclitaxel
    Dosage: over 3 hours on day 1 (cycles, 1-6).
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-31



Possible Carboplatin side effects in female

Reported by a physician from United States on 2012-07-19

Patient: female, weighing 57.9 kg (127.4 pounds)

Reactions: White Blood Cell Count Decreased, Diarrhoea, Otitis Externa, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 128 milligram
    Indication: Breast Cancer
    Start date: 2012-04-17
    End date: 2012-06-26

Abraxane
    Dosage: 118 milligram

Carboplatin
    Dosage: 720 milligram
    Indication: Breast Cancer
    Start date: 2012-04-17
    End date: 2012-06-26

Herceptin
    Dosage: 120 milligram
    Start date: 2012-06-05

Herceptin
    Dosage: 120 milligram
    Start date: 2012-06-12

Herceptin
    Dosage: 2 milligram
    Start date: 2012-05-29

Other drugs received by patient: Ciprofloxacin; Zofran; Neurontin; Protonix; Colace; Lovenox; Neurontin; Neupogen; Ciprofloxacin; Atenolol; Zolpidem; Magnesium Sulfate; Imodium; K-TAB; Vicodin; Zosyn; Zofran; Vancomycin; Levaquin; Morphine Sulfate; Ciprofloxacin HCL; Augmentin '500'; Acyclovir



Possible Carboplatin side effects in 35 year old female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-18

Patient: 35 year old female

Reactions: Abdominal Pain, Vomiting, Nausea, Diarrhoea, Pyrexia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: auc5, in one hour, intravenous (not otherwise specified)
    Indication: Cervix Carcinoma

Cisplatin
    Dosage: 40 mg, weekly for 5 doses
    Indication: Cervix Carcinoma

Paclitaxel
    Dosage: 155 mg/m**2, over 3 hours
    Indication: Cervix Carcinoma

Other drugs received by patient: Sodium Chloride; Phenergan; Ranitidine; Serotonin (5ht3) Antagonists; Dexamethasone



Possible Carboplatin side effects in 63 year old female

Reported by a physician from United States on 2012-07-18

Patient: 63 year old female, weighing 122.7 kg (270.0 pounds)

Reactions: Vomiting, Nausea, Pain, Anaemia, Hypokalaemia, Haemoglobin Decreased, Diarrhoea, Skin Ulcer, Hypomagnesaemia, Dehydration, Hypoalbuminaemia, Hypocalcaemia, Vaginal Infection, Blood Creatinine Increased, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: over 30-90 minutes on day 1,starting with cycle 2 x6 cycles, no prior radiotherapy
    Indication: Endometrial Cancer
    Start date: 2011-05-02

Avastin
    Dosage: prior radiotherapy, iv over 30-90 minutes on day 1 (

Carboplatin
    Dosage: auc = 5 iv over 30 minutes on day 1 x 6 cycles

Carboplatin
    Dosage: no prior radiotherapy, auc = 6 iv over 30 minutes on day 1 x 6 cycles
    Indication: Endometrial Cancer
    Start date: 2011-05-02

Paclitaxel
    Dosage: prior radiotherapy,over 3 hrs on day 1 x 6 cycles

Paclitaxel
    Dosage: no prior radiotherapy, iv over 3 hrs on day 1 x 6 cycles
    Indication: Endometrial Cancer
    Start date: 2011-05-02

Other drugs received by patient: Arixtra; Percocet; Lyrica



Possible Carboplatin side effects in female

Reported by a individual with unspecified qualification from United States on 2012-07-17

Patient: female, weighing 66.1 kg (145.4 pounds)

Reactions: Diarrhoea, Respiratory Failure, Cardiac Arrest, Cardiogenic Shock

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bevacizumab (Rhumab Vegf)
    Dosage: 3934 mg

Carboplatin
    Dosage: 2965 mg

Paclitaxel
    Dosage: 1296 mg



Possible Carboplatin side effects in female

Reported by a physician from United States on 2012-07-16

Patient: female, weighing 66.0 kg (145.2 pounds)

Reactions: Vomiting, Nausea, Diarrhoea, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: two doses held due to anc below 800 on 5/17/2012 and 6/1/2012

Paclitaxel
    Dosage: two doses held as anc below 800 on 5/17/2012 and 6/8/2012

Other drugs received by patient: Simvastatin; Ativan; Metformin Hydrochloride; Onglyza; Levothyroxine Sodium; Lisinopril



Possible Carboplatin side effects in female

Reported by a individual with unspecified qualification from United States on 2012-07-16

Patient: female, weighing 66.1 kg (145.4 pounds)

Reactions: Diarrhoea, Unresponsive To Stimuli, Cardiac Arrest

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bevacizumab (Rhumab Vegf) 3934 MG
    Dosage: 3934 mg

Carboplatin
    Dosage: 2965 mg

Paclitaxel
    Dosage: 1296 mg



Possible Carboplatin side effects in 59 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-13

Patient: 59 year old female, weighing 58.9 kg (129.6 pounds)

Reactions: Otitis Externa, Skin Hyperpigmentation, Hypoacusis, Neuropathy Peripheral, Diarrhoea, Ear Pain, Otitis Media, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 128 mg iv, 118 mg iv
    Indication: Chemotherapy
    Start date: 2012-04-17
    End date: 2012-06-26

Carboplatin
    Dosage: 720 mg
    Indication: Chemotherapy
    Start date: 2012-04-17
    End date: 2012-06-26

Other drugs received by patient: Zofren 8 MG; Atenolol; Neurontin



Possible Carboplatin side effects in 71 year old male

Reported by a physician from Greece on 2012-07-11

Patient: 71 year old male, weighing 69.0 kg (151.8 pounds)

Reactions: Abdominal Pain, Diarrhoea, Sepsis, Tachypnoea, Febrile Neutropenia, Acute Respiratory Failure

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-25

Carboplatin
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-25

Xeloda
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-25

Other drugs received by patient: Lipidil; Indapamide; Exforge; Kerlone



Possible Carboplatin side effects in 47 year old male

Reported by a individual with unspecified qualification from United Kingdom on 2012-07-09

Patient: 47 year old male, weighing 113.0 kg (248.6 pounds)

Reactions: Contusion, Diarrhoea, International Normalised Ratio Increased, Swelling, Drug Interaction, Rash, Haematoma

Drug(s) suspected as cause:
Carboplatin

Other drugs received by patient possibly interacting with the suspect drug:
Alprazolam
    Indication: Product Used FOR Unknown Indication

Bevacizumab
    Indication: Product Used FOR Unknown Indication

Cimetidine
    Indication: Product Used FOR Unknown Indication

Citalopram Hydrobromide
    Indication: Product Used FOR Unknown Indication

Darbepoetin Alfa
    Indication: Product Used FOR Unknown Indication

Dexamethasone
    Indication: Product Used FOR Unknown Indication

Diphenhydramine HCL
    Indication: Product Used FOR Unknown Indication

Erlotinib Hydrochloride
    Dosage: drug with drawan
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Granisetron
    Indication: Product Used FOR Unknown Indication

Loperamide
    Indication: Product Used FOR Unknown Indication

Oxycodone Hydrochloride
    Indication: Pain

Paclitaxel
    Indication: Product Used FOR Unknown Indication

Vitamin K TAB
    Indication: Product Used FOR Unknown Indication

Warfarin Sodium
    Indication: Product Used FOR Unknown Indication



Possible Carboplatin side effects in male

Reported by a physician from Belgium on 2012-07-09

Patient: male, weighing 73.0 kg (160.6 pounds)

Reactions: Colitis Ischaemic, Vomiting, Nausea, Rectal Haemorrhage, Constipation, Faecaloma, Diarrhoea, Abdominal Symptom, Diarrhoea Haemorrhagic, Feeling of Body Temperature Change, Muscle Spasms, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Testicular Neoplasm
    Start date: 2012-04-17
    End date: 2012-05-08

Zofran
    Start date: 2012-04-17
    End date: 2012-05-08

Zofran
    Dosage: 8mg twice per day
    Administration route: Oral
    Indication: Nausea
    Start date: 2012-04-18
    End date: 2012-05-11

Other drugs received by patient: Solu-Medrol; Medrol



Possible Carboplatin side effects in 30 year old female

Reported by a physician from United States on 2012-07-09

Patient: 30 year old female

Reactions: Nausea, Diarrhoea, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Brentuximab Vedotin (Brentuximab Vedotin) Injection
    Indication: non-Hodgkin's Lymphoma Recurrent
    Start date: 2012-04-18
    End date: 2012-06-14

Carboplatin
    Indication: non-Hodgkin's Lymphoma Recurrent
    End date: 2012-06-14

Etoposide
    Indication: non-Hodgkin's Lymphoma Recurrent
    End date: 2012-06-14

Ifosfamide
    Indication: non-Hodgkin's Lymphoma Recurrent
    End date: 2012-06-14

Other drugs received by patient: Pantoprazole; Prochlorperazine (Prochlorperazine Maleate); Aprepitant; Pegfilgrastim (Pegfilgrastim); Senna-Mint WAF; Dexamethasone Sodium Phosphate; Enoxaprin Sodium (Enoxaparin Sodium); Ondansetron; Ambien; Lorazepam; Docusate Sodium (Docusate Sodium); Leuprolide Acetate; Omeprazole



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