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Carboplatin (Carboplatin) - Anaemia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Anaemia (233)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Carboplatin where reactions include anaemia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 233   Next >>

Possible Carboplatin side effects in 65 year old female

Reported by a physician from Japan on 2012-08-24

Patient: 65 year old female, weighing 50.2 kg (110.6 pounds)

Reactions: Weight Decreased, Blood Bilirubin Increased, Cytomegalovirus Viraemia, Headache, Pyrexia, Interstitial Lung Disease, Oedema, Thrombocytopenia, Blood Sodium Decreased, Decreased Appetite, Vomiting, Stomatitis, Pneumonia, Alanine Aminotransferase Increased, Lymphopenia, Anaemia, Febrile Neutropenia, Rash, Blood Phosphorus Decreased, Blood Potassium Decreased, Diarrhoea, Alopecia, Aspartate Aminotransferase Increased, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Dosage: 30 mg/m2 x 1/4 week
    Start date: 2011-03-16

Adriamycin PFS
    Dosage: 40 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Carboplatin
    Dosage: 250 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 350 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Etoposide
    Dosage: 100 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Prednisolone
    Dosage: 1mg/kg x 1/2 week
    Start date: 2011-12-13
    End date: 2011-12-14

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Start date: 2011-03-16

Prednisolone
    Dosage: 2 mg/m2, 1x/day
    Administration route: Oral
    Start date: 2011-03-24

Ranimustine
    Dosage: 60 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-16

Vincristine Sulfate
    Dosage: 1 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Vindesine Sulfate
    Dosage: 2.4 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Other drugs received by patient: Mucosolvan; Lansoprazole; Sulfamethoxazole and Trimethoprim; Armodafinil; Zolpidem; Olopatadine HCL; Cefazolin Sodium; Ciprofloxacin HCL; Armodafinil; Zovirax; Magmitt; Alendronate Sodium



Possible Carboplatin side effects in female

Reported by a physician from United States on 2012-08-23

Patient: female, weighing 81.1 kg (178.5 pounds)

Reactions: Anaemia, Lymphocyte Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 625 mg

Taxol
    Dosage: 320 mg



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-08-23

Patient: female, weighing 62.0 kg (136.4 pounds)

Reactions: Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Breast Cancer
    Start date: 2012-06-15

Lapatinib
    Dosage: 750mg per day
    Indication: Breast Cancer
    Start date: 2012-06-15

Liposome Encapsulated Doxorubicin Citrate Complex
    Dosage: 20mgm2 weekly
    Indication: Breast Cancer
    Start date: 2012-06-15

Paclitaxel
    Dosage: 80mgm2 weekly
    Indication: Breast Cancer
    Start date: 2012-06-15

Trastuzumab
    Dosage: 6mgk every 3 weeks
    Indication: Breast Cancer
    Start date: 2012-06-15

Other drugs received by patient: Loperamide; Neupogen



Possible Carboplatin side effects in male

Reported by a physician from Hungary on 2012-08-22

Patient: male, weighing 74.0 kg (162.8 pounds)

Reactions: Pneumonia, Anaemia, Granulocytopenia, Neutropenia, Thrombocytopenia, Leukopenia, Infectious Pleural Effusion

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: frequency: 1x, form infusion;
    Indication: non-Small Cell Lung Cancer

Avastin
    Dosage: frequency as per protocol, last dose of prior to event on 25 january 2010. form infusion

Avastin
    Dosage: last dose prior to sae: 16 february 2010. last dose prior to leukopenia was 23 mar 2010

Avastin
    Dosage: last dose prior to sae: 16 february 2010,infusion, frequency: 1xdaily

Carboplatin
    Dosage: last dose prior to event on 25 january 2010.

Carboplatin
    Dosage: form: infusion;
    Indication: non-Small Cell Lung Cancer

Carboplatin
    Dosage: last dose prior to sae: 23 march 2010, frequency: 1xdaily

Carboplatin

Gemcitabine Hydrochloride
    Dosage: last dose prior to sae: 01 april 2010

Gemcitabine Hydrochloride

Gemcitabine Hydrochloride
    Dosage: freq: day 1 + 8 every 3 weeks

Gemcitabine Hydrochloride
    Dosage: last dose of iv gemcitabine prior to event on 25 january 2010.

Gemcitabine Hydrochloride
    Dosage: freq: day 1 + 8 every 3 weeks

Gemcitabine Hydrochloride
    Dosage: form infusion, on day 1 and day 8; frequency: 1xdaily;
    Indication: non-Small Cell Lung Cancer
    Start date: 2009-11-09
    End date: 2009-11-17

Gemcitabine Hydrochloride
    Dosage: frequency: 2xevery three week, form: infusion

Other drugs received by patient: Fluticasone Propionate / Salmeterol; Augmentin '500'; Kalium-R; Sinecod; Ondansetron; Bisoprolol Fumarate; Pegfilgrastim; Lidocaine; Ciprofloxacin Hydrochloride; Neupogen; Spiriva; Kalium-R; Eprex; Neorecormon; Hydromorphone HCL; Berodual; Fluticasone Propionate / Salmeterol; Neorecormon; Augmentin '500'; Kalium-R; Medrol; Medrol; Neupogen; Medrol; Bisoprolol Fumarate; Spiriva; Megesin; Megesin



Possible Carboplatin side effects in female

Reported by a individual with unspecified qualification from United States on 2012-08-22

Patient: female, weighing 81.1 kg (178.5 pounds)

Reactions: Refusal of Treatment by Patient, Anaemia, Lymphocyte Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 625 mg

Taxol
    Dosage: 320 mg



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-22

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Avastin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Cisplatin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Pemetrexed Disodium
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Other drugs received by patient: Crestor; Potassium Chloride; Norfloxacin; Dolpasse



Possible Carboplatin side effects in 54 year old female

Reported by a physician from United States on 2012-08-22

Patient: 54 year old female, weighing 47.0 kg (103.4 pounds)

Reactions: Abdominal Pain, Vomiting, Nausea, Anaemia, Hypokalaemia, Small Intestinal Obstruction, Hypomagnesaemia, Platelet Count Decreased, Hypoalbuminaemia, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: last dose prior to sae was taken on 29/jun/2012
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-06-29

Carboplatin
    Dosage: auc= 6 over 30 minutes on day 1. last dose prior to sae was taken on 29/may/2012
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-05-29

Paclitaxel
    Dosage: last dose prior to sae was taken on 06/jul/2012. day 15 held due to sbo.
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-07-06

Veliparib
    Dosage: last dose prior to sae was taken on 03/jul/2012
    Administration route: Oral
    Indication: Ovarian Epithelial Cancer



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-21

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration, Hypokalaemia

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Avastin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Cisplatin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Pemetrexed Disodium
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Other drugs received by patient: Crestor; Dolpasse; Potassium Chloride; Norfloxacin



Possible Carboplatin side effects in 54 year old female

Reported by a physician from United States on 2012-08-21

Patient: 54 year old female, weighing 68.0 kg (149.6 pounds)

Reactions: White Blood Cell Count Decreased, Anaemia, Febrile Neutropenia, Pancytopenia, Platelet Count Decreased, Device Related Infection, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Dosage: 10 mg/kg, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Carboplatin
    Dosage: 6 df, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Cyclophosphamide
    Dosage: 600 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Doxorubicin HCL
    Dosage: 60 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Paclitaxel
    Dosage: 80 mg/m2, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Pegfilgrastim
    Dosage: 480 mug, unk
    Indication: Chemotherapy
    Start date: 2011-12-22

Other drugs received by patient: Tylenol (Caplet); Emend; Levaquin; Decadron; Zofran / 00955302 /; Aloxi; Compazine



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-08-20

Patient: female, weighing 62.0 kg (136.4 pounds)

Reactions: Fatigue, Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Indication: Breast Cancer
    Start date: 2012-05-18
    End date: 2012-08-09

Carboplatin
    Indication: Breast Cancer
    Start date: 2012-05-18
    End date: 2012-08-09

Doxorubicin HCL
    Indication: Breast Cancer
    Start date: 2012-05-18
    End date: 2012-08-09

Paclitaxel
    Indication: Breast Cancer
    Start date: 2012-05-18
    End date: 2012-08-09



Possible Carboplatin side effects in

Reported by a physician from United States on 2012-08-13

Patient:

Reactions: Thrombosis, Pneumonia, Haemorrhage, Anaemia, Procedural Site Reaction, Ulcer Haemorrhage, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 812 mg
    End date: 2012-07-10

Fluorouracil
    Dosage: 7160 mg
    End date: 2012-07-14



Possible Carboplatin side effects in 43 year old female

Reported by a physician from United States on 2012-07-30

Patient: 43 year old female, weighing 121.0 kg (266.2 pounds)

Reactions: Vomiting, Dyspnoea, Nausea, Anaemia, Hypokalaemia, Diarrhoea, Hypophagia, Dehydration, NO Therapeutic Response, Fluid Intake Reduced

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 100mg/m2 weekly iv
    Indication: Breast Cancer
    Start date: 2012-03-26
    End date: 2012-05-11

Carboplatin
    Dosage: auc 4.5 qwk iv
    Indication: Breast Cancer
    Start date: 2012-03-26
    End date: 2012-05-04

Other drugs received by patient: Depakote; Metformin Hydrochloride; Compazine; Crestor; Detrol; Hydrochlorothiazide; Prozac; Motrin



Possible Carboplatin side effects in 67 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-24

Patient: 67 year old male, weighing 155.0 kg (341.0 pounds)

Reactions: Syncope, Dehydration, Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 1df=2.25auc last dose on 27mar2012
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-01-23

Pemetrexed Disodium
    Dosage: 23jan12-12feb12,5mar02-5mar2012(3654d) 188mg/m2:27mar2012
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-01-23

Other drugs received by patient: Triamterene; Metoprolol Succinate; Folic Acid; Decadron; Denosumab; Magnesium Oxide; Potassium Chloride; Mirtazapine; Calcium Carbonate; Neulasta; Vitamin B-12



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-07-24

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Anaemia, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: dose: auc 2min/ml, last dose prior to sae on: 11/jun/2012
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19

Doxorubicin Hydrochloride
    Dosage: last dose prior to sae on: 11/jun/2012
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19

Herceptin
    Dosage: date of last dose prior to sae: 18/may/2012
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19

Lapatinib
    Dosage: last dose prior to sae:18 jun 2012
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19

Paclitaxel
    Dosage: last dose prior to sae on: 11/jun/2012
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19



Possible Carboplatin side effects in 60 year old female

Reported by a physician from United States on 2012-07-24

Patient: 60 year old female, weighing 111.2 kg (244.6 pounds)

Reactions: Abdominal Pain, White Blood Cell Count Decreased, Anaemia, Hyperglycaemia, International Normalised Ratio Increased, Hyponatraemia, Device Related Infection, Seroma, Hypophosphataemia, Skin Ulcer, Proteinuria, Platelet Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: over 30-90 minutes on day 1 (starting with cycle 2 for those patients entering post surgery) x 6 cyc
    Indication: Endometrial Cancer
    Start date: 2011-01-13

Avastin
    Dosage: maintainence therapy (cycles 7+), over 30-90 mins on day 1

Carboplatin
    Dosage: auc = 6 iv over 30 minutes on day 1 x 6 cycles, last dose prior to sae: 27/feb/2012
    Indication: Endometrial Cancer
    Start date: 2011-01-13

Paclitaxel
    Dosage: over 3 hrs on day 1 x 6 cycles, last dose prior to sae: 27/feb/2012
    Indication: Endometrial Cancer
    Start date: 2011-01-13



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Germany on 2012-07-23

Patient: 65 year old female, weighing 46.4 kg (102.1 pounds)

Reactions: Weight Decreased, Fistula, Nausea, Anaemia, General Physical Health Deterioration, Fatigue, Sepsis, Decreased Appetite, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Ovarian Cancer
    Start date: 2012-03-21
    End date: 2012-04-18

Avastin
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Carboplatin
    Dosage: auc 5,
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Carboplatin
    Dosage: auc 5, last dose:15/may/2012
    End date: 2012-06-10

Paclitaxel
    Dosage: last dose:15/may/2012
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Paclitaxel
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Other drugs received by patient: Novalgin; Pantoprazole; Zolpidem



Possible Carboplatin side effects in 62 year old male

Reported by a physician from Japan on 2012-07-19

Patient: 62 year old male

Reactions: Blood Pressure Increased, Anaemia, Posterior Reversible Encephalopathy Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: auc 6 min-mg/ml on day 1 every 3 weeks
    Indication: Adenosquamous Cell Lung Cancer Stage III

Paclitaxel
    Dosage: 200mg/m2 on day 1 every 3 weeks
    Indication: Adenosquamous Cell Lung Cancer Stage III

Other drugs received by patient: Paraplatin; Paclitaxel



Possible Carboplatin side effects in 62 year old male

Reported by a individual with unspecified qualification from Japan on 2012-07-18

Patient: 62 year old male

Reactions: Blood Pressure Increased, Head Discomfort, Oral Disorder, Anaemia, Posterior Reversible Encephalopathy Syndrome

Drug(s) suspected as cause:
Carboplatin
    Dosage: auc 6 min mg/ml intravenous (not otherwise specified)
    Indication: non-Small Cell Lung Cancer

Paclitaxel
    Dosage: 200 mg/m2, intravenous (not specified)
    Indication: non-Small Cell Lung Cancer

Other drugs received by patient: Dexamethasone Sodium Phosphate



Possible Carboplatin side effects in 63 year old female

Reported by a physician from United States on 2012-07-18

Patient: 63 year old female, weighing 122.7 kg (270.0 pounds)

Reactions: Vomiting, Nausea, Pain, Anaemia, Hypokalaemia, Haemoglobin Decreased, Diarrhoea, Skin Ulcer, Hypomagnesaemia, Dehydration, Hypoalbuminaemia, Hypocalcaemia, Vaginal Infection, Blood Creatinine Increased, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: over 30-90 minutes on day 1,starting with cycle 2 x6 cycles, no prior radiotherapy
    Indication: Endometrial Cancer
    Start date: 2011-05-02

Avastin
    Dosage: prior radiotherapy, iv over 30-90 minutes on day 1 (

Carboplatin
    Dosage: auc = 5 iv over 30 minutes on day 1 x 6 cycles

Carboplatin
    Dosage: no prior radiotherapy, auc = 6 iv over 30 minutes on day 1 x 6 cycles
    Indication: Endometrial Cancer
    Start date: 2011-05-02

Paclitaxel
    Dosage: prior radiotherapy,over 3 hrs on day 1 x 6 cycles

Paclitaxel
    Dosage: no prior radiotherapy, iv over 3 hrs on day 1 x 6 cycles
    Indication: Endometrial Cancer
    Start date: 2011-05-02

Other drugs received by patient: Arixtra; Percocet; Lyrica



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-07-17

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Anaemia, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02
    End date: 2012-06-19

Doxorubicin HCL
    Dosage: 20mgm2 weekly
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02
    End date: 2012-06-19

Lapatinib
    Dosage: 500mg per day
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02
    End date: 2012-06-19

Paclitaxel
    Dosage: 80mgm2 weekly
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02
    End date: 2012-06-19

Trastuzumab
    Dosage: 6mg every 3 weeks
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02
    End date: 2012-06-19



Possible Carboplatin side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-06

Patient: male

Reactions: Blood Alkaline Phosphatase Increased, Blood Pressure Increased, Anaemia, Posterior Reversible Encephalopathy Syndrome, Eyelid Ptosis, Platelet Count Decreased, Headache

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: auc 6 min?mg/ml
    Indication: Adenosquamous Cell Lung Cancer Stage III

Paclitaxel
    Dosage: 200 mg/m2, unk
    Indication: Adenosquamous Cell Lung Cancer Stage III

Other drugs received by patient: Dexamethasone



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-07-05

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Anaemia, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: dose: 2 auc, last dose: 11 jun 2012
    Indication: Breast Cancer
    Start date: 2012-02-02

Doxorubicin HCL
    Dosage: last dose: 11 jun 2012
    Indication: Breast Cancer
    Start date: 2012-02-02

Herceptin
    Dosage: last dose: 18-may-2012
    Indication: Breast Cancer
    Start date: 2012-02-02

Lapatinib
    Dosage: frequency: daily, last dose prior to sae:18 jun 2012
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-02-02

Paclitaxel
    Dosage: last dose: 11 jun 2012
    Indication: Breast Cancer
    Start date: 2012-02-02



Possible Carboplatin side effects in 60 year old female

Reported by a individual with unspecified qualification from United States on 2012-07-02

Patient: 60 year old female, weighing 111.2 kg (244.6 pounds)

Reactions: Abdominal Pain, White Blood Cell Count Decreased, Anaemia, International Normalised Ratio Increased, Hyperglycaemia, Hyponatraemia, Device Related Infection, Seroma, Hypophosphataemia, Skin Ulcer, Proteinuria, Platelet Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: maintainence therapy (cycles 7+), over 30-90 mins on day 1

Avastin
    Dosage: over 30-90 minutes on day 1 (starting with cycle 2 for those patients entering post surgery) x 6 cyc
    Indication: Endometrial Cancer
    Start date: 2011-01-13

Carboplatin
    Dosage: auc = 6 iv over 30 minutes on day 1 x 6 cycles, last dose prior to sae: 27/feb/2012
    Indication: Endometrial Cancer
    Start date: 2011-01-13

Paclitaxel
    Dosage: over 3 hrs on day 1 x 6 cycles, last dose prior to sae: 27/feb/2012
    Indication: Endometrial Cancer
    Start date: 2011-01-13



Possible Carboplatin side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02

Patient: female, weighing 120.6 kg (265.3 pounds)

Reactions: Vomiting, Hypersensitivity, Neutrophil Count, Nausea, Anaemia, Constipation, Hypokalaemia, Haemoglobin Decreased, Fatigue, Platelet Count Decreased, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Ovarian Cancer
    Start date: 2012-02-29
    End date: 2012-03-21

Carboplatin
    Dosage: dose: 5 auc
    Start date: 2012-03-21
    End date: 2012-04-11

Carboplatin
    Dosage: dose: 6 auc
    Indication: Ovarian Cancer
    Start date: 2012-02-29
    End date: 2012-04-11

Paclitaxel
    Indication: Ovarian Cancer
    Start date: 2012-02-29
    End date: 2012-04-11

Other drugs received by patient: Palonosetron; Ranitidine; Colace; Dexamethasone; Lovenox; Benadryl; Reglan



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-07-02

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Anaemia, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02
    End date: 2012-06-19

Doxorubicin HCL
    Dosage: 20mgm2 weekly
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02
    End date: 2012-06-19

Lapatinib
    Dosage: 500mg per day
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02

Paclitaxel
    Dosage: 80mgm2 weekly
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02
    End date: 2012-06-19

Trastuzumab
    Dosage: 6mg every 3 weeks
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02
    End date: 2012-06-19



Possible Carboplatin side effects in 66 year old female

Reported by a physician from United States on 2012-07-02

Patient: 66 year old female, weighing 75.0 kg (165.0 pounds)

Reactions: Vomiting, Diarrhoea, Nausea, Anaemia, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: latest received date:08/mar/2012
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-02-16

Carboplatin
    Dosage: latest received date: 22/may/2012
    Indication: Ovarian Epithelial Cancer

Paclitaxel
    Dosage: latest received date: 22/may/2012
    Indication: Ovarian Epithelial Cancer



Possible Carboplatin side effects in male

Reported by a physician from United States on 2012-06-28

Patient: male, weighing 70.3 kg (154.7 pounds)

Reactions: Pain, Anaemia, Dehydration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 1200 mg

Taxol
    Dosage: 388 mg



Possible Carboplatin side effects in 65 year old female

Reported by a physician from Germany on 2012-06-28

Patient: 65 year old female, weighing 46.4 kg (102.1 pounds)

Reactions: Weight Decreased, Fistula, Fatigue, Nausea, Sepsis, Anaemia, General Physical Health Deterioration, Decreased Appetite, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Ovarian Cancer
    Start date: 2012-03-21
    End date: 2012-04-18

Avastin
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Carboplatin
    Dosage: auc 5,
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Carboplatin
    Dosage: auc 5, last dose:15/may/2012
    End date: 2012-06-10

Paclitaxel
    Dosage: last dose:15/may/2012
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Paclitaxel
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Other drugs received by patient: Pantoprazole; Zolpidem; Novalgin



Possible Carboplatin side effects in 54 year old female

Reported by a physician from United States on 2012-06-26

Patient: 54 year old female, weighing 68.0 kg (149.6 pounds)

Reactions: White Blood Cell Count Decreased, Anaemia, Platelet Count Decreased, Pancytopenia, Febrile Neutropenia, Device Related Infection, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Dosage: 10 mg/kg, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Carboplatin
    Dosage: 6 df, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Cyclophosphamide
    Dosage: 600 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Doxorubicin HCL
    Dosage: 60 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Paclitaxel
    Dosage: 80 mg/m2, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Pegfilgrastim
    Dosage: 480 mug, unk
    Indication: Chemotherapy
    Start date: 2011-12-22

Other drugs received by patient: Aloxi; Compazine; Decadron; Emend; Zofran; Tylenol (Caplet); Levaquin



Possible Carboplatin side effects in female

Reported by a physician from Germany on 2012-06-26

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Anaemia, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02

Doxorubicin HCL
    Dosage: 20mgm2 weekly
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02

Lapatinib
    Dosage: 500mg per day
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02

Paclitaxel
    Dosage: 80mgm2 weekly
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02

Trastuzumab
    Dosage: 6mg every 3 weeks
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-02



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