This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Caprelsa (Vandetanib) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (99)
Death (10)
Life Threatening Events (1)
Reports by Reaction Type
Diarrhoea (29),
Rash (26),
Fatigue (21),
Electrocardiogram QT Prolonged (15),
Acne (14),
Blood Pressure Increased (13),
Dyspnoea (13),
Nausea (9),
Joint Swelling (8),
Arthralgia (8),
Hot Flush (7),
Muscle Spasms (7)
Below are a few examples of reports where side effects / adverse reactions may be related to Caprelsa (Vandetanib). For a complete list or a specific selection of reports, please use the links above.
Possible Caprelsa side effects in 29 year old female
Reported by a consumer/non-health professional from United States on 2012-08-27
Patient: 29 year old female
Reactions: Blood Pressure Increased, Vomiting, Nausea, Blood Thyroid Stimulating Hormone Increased, Rash, Constipation, Blood Electrolytes Decreased, Tumour Lysis Syndrome, Diarrhoea
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Caprelsa
Other drugs received by patient: Synthroid; Calcium; Imodium; Vitamin D
Possible Caprelsa side effects in 32 year old male
Reported by a individual with unspecified qualification from United States on 2012-08-22
Patient: 32 year old male, weighing 53.9 kg (118.6 pounds)
Reactions: Electrocardiogram QT Prolonged, Acne, Skin Sensitisation
Drug(s) suspected as cause:
Caprelsa
Administration route: Oral
Indication: Multiple Myeloma
Start date: 2012-04-26
End date: 2012-07-05
Caprelsa
Administration route: Oral
Indication: Thyroid Cancer
Start date: 2012-04-26
End date: 2012-07-05
Caprelsa
Administration route: Oral
Indication: Thyroid Disorder
Start date: 2012-04-26
End date: 2012-07-05
Other drugs received by patient: Oxycontin; Synthroid; Oxycontin
Possible Caprelsa side effects in 79 year old male
Reported by a physician from United States on 2012-08-22
Patient: 79 year old male, weighing 77.6 kg (170.7 pounds)
Reactions: Mental Status Changes, Hypoacusis, Fatigue, Muscle Spasms, Back Pain, Dermatitis Acneiform, Dyspnoea, Haemoptysis, Urinary Tract Infection, Palmar-Plantar Erythrodysaesthesia Syndrome, Amnesia, Joint Swelling, Arthralgia, Insomnia, Increased Tendency To Bruise, Haemorrhagic Diathesis, Vision Blurred, Asthenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Caprelsa
Other drugs received by patient: Metformin; Nitrostat; Plavix; Icaps; Aspirin; Benadryl; Prednisone TAB; Niacin; Synthroid; Lisinopril; Zocor; Niacin; Iron; Januvia
Possible Caprelsa side effects in
Reported by a pharmacist from United States on 2012-08-20
Patient:
Reactions: Convulsion
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 72 year old male
Reported by a individual with unspecified qualification from United States on 2012-08-17
Patient: 72 year old male
Reactions: Diarrhoea, Insomnia, DRY Mouth, Hypertension
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 45 year old male
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: 45 year old male
Reactions: Procedural Complication, Vocal Cord Paralysis
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-14
Patient: male
Reactions: Palmar-Plantar Erythrodysaesthesia Syndrome
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 42 year old male
Reported by a consumer/non-health professional from United States on 2012-08-07
Patient: 42 year old male
Reactions: Blood Thyroid Stimulating Hormone Increased
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in
Reported by a physician from United States on 2012-08-07
Patient:
Reactions: Therapeutic Response Unexpected, Constipation
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 60 year old male
Reported by a physician from United States on 2012-08-06
Patient: 60 year old male
Reactions: Cerebrovascular Accident, Disease Progression
Adverse event resulted in: death
Drug(s) suspected as cause:
Caprelsa
Other drugs received by patient: Tretinoin
Possible Caprelsa side effects in male
Reported by a physician from United States on 2012-08-06
Patient: male, weighing 78.8 kg (173.4 pounds)
Reactions: Pruritus Generalised, Face Oedema, Conjunctival Oedema, Erythema, Skin Reaction, Rash Macular
Drug(s) suspected as cause:
Caprelsa
Administration route: Oral
Start date: 2012-04-05
End date: 2012-06-08
Caprelsa
Administration route: Oral
Start date: 2012-06-14
Caprelsa
Administration route: Oral
Indication: Thyroid Cancer
Other drugs received by patient: Flomax; Lipitor; Norvasc; Pepcid; Triamcinolone Acetonide; Levothroid; Avodart; Vandetanib; Aspirin; Vitamin D; Vanicream; Aspirin
Possible Caprelsa side effects in 79 year old male
Reported by a individual with unspecified qualification from United States on 2012-08-06
Patient: 79 year old male
Reactions: Cardiac Failure Congestive
Adverse event resulted in: death
Drug(s) suspected as cause:
Caprelsa
Other drugs received by patient: Metformin HCL; Simvastatin; Uroxatral; Symbicort; Synthroid; Fentanyl Citrate; Aspirin; Paroxetine HCL; Omeprazole; Singulair; Digoxin
Possible Caprelsa side effects in male
Reported by a physician from United States on 2012-08-01
Patient: male
Reactions: Off Label Use, Fatigue, Dyspnoea
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 51 year old female
Reported by a physician from United States on 2012-08-01
Patient: 51 year old female
Reactions: Fatigue, Impaired Work Ability, Rash
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 79 year old male
Reported by a individual with unspecified qualification from United States on 2012-08-01
Patient: 79 year old male
Reactions: Cardiac Failure Congestive
Adverse event resulted in: death
Drug(s) suspected as cause:
Caprelsa
Other drugs received by patient: Singulair; Synthroid; Aspirin; Paroxetine HCL; Symbicort; Fentanyl Citrate; Metformin HCL; Uroxatral; Digoxin; Omeprazole; Simvastatin
Possible Caprelsa side effects in 79 year old female
Reported by a individual with unspecified qualification from United States on 2012-07-31
Patient: 79 year old female
Reactions: Fatigue, Diarrhoea, Head Injury, Coma, Fall, Traumatic Haematoma
Adverse event resulted in: death
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 47 year old male
Reported by a individual with unspecified qualification from United States on 2012-07-25
Patient: 47 year old male
Reactions: Dyspnoea, Joint Swelling, Arthralgia, Rash
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 50 year old female
Reported by a individual with unspecified qualification from Canada on 2012-07-23
Patient: 50 year old female
Reactions: Electrocardiogram Abnormal
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 71 year old male
Reported by a consumer/non-health professional from United States on 2012-07-19
Patient: 71 year old male
Reactions: Dyspnoea, Diarrhoea, Muscular Weakness, Rash, Abdominal Pain Upper, Cough
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 56 year old male
Reported by a individual with unspecified qualification from United States on 2012-07-18
Patient: 56 year old male
Reactions: Poor Quality Sleep, Fatigue, Hot Flush, Rash, Muscle Twitching
Drug(s) suspected as cause:
Caprelsa
Other drugs received by patient: Levothyroxine Sodium; Oxicodone HCI; Cymbalta; Lisinopril; Neurontin; Oxycontin; Ambien
Possible Caprelsa side effects in 32 year old male
Reported by a individual with unspecified qualification from United States on 2012-07-16
Patient: 32 year old male
Reactions: Electrocardiogram QT Prolonged, Acne, Skin Sensitisation
Drug(s) suspected as cause:
Caprelsa
Administration route: Oral
Indication: Thyroid Cancer
Caprelsa
Administration route: Oral
Indication: Thyroid Disorder
Other drugs received by patient: Oxycontin; Synthroid; Oxycontin
Possible Caprelsa side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-13
Patient: male
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 70 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-12
Patient: 70 year old male
Reactions: Keratopathy
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 72 year old male
Reported by a consumer/non-health professional from United States on 2012-07-12
Patient: 72 year old male
Reactions: Blood Urine Present, Drug Level Increased, Feeling Abnormal, Muscle Spasms
Drug(s) suspected as cause:
Caprelsa
Administration route: Oral
Indication: Thyroid Cancer
Coumadin
Administration route: Oral
Other drugs received by patient: Toprol-XL; Pancreaze; Imodium A-D
Possible Caprelsa side effects in 64 year old male
Reported by a consumer/non-health professional from United States on 2012-07-12
Patient: 64 year old male
Reactions: Blood Pressure Increased, Polycythaemia, Dyspnoea, Acne, Musculoskeletal Chest Pain, Rash, Hypokalaemia, Diarrhoea, Hypomagnesaemia
Drug(s) suspected as cause:
Caprelsa
Other drugs received by patient: Avodart; Synthroid; Calcitriol; Pepcid AC; Levothyroxine Sodium; Pepcid AC; Docusate Sodium; Benicar; Multivital; Famotidine; Senna Leaves; Multi-Vitamin; Slow-MAG; Hyrdocodone-Acetaminophen
Possible Caprelsa side effects in
Reported by a physician from United States on 2012-07-11
Patient:
Reactions: Electrocardiogram QT Interval Abnormal
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 63 year old male
Reported by a individual with unspecified qualification from United States on 2012-07-10
Patient: 63 year old male
Reactions: Glossodynia, Acne
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 69 year old female
Reported by a pharmacist from United States on 2012-07-09
Patient: 69 year old female
Reactions: Dysgeusia, Electrocardiogram QT Prolonged, Dyspnoea
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Caprelsa
Other drugs received by patient: Atenolol; Lexapro; Synthroid; Prochlorperazine Maleate
Possible Caprelsa side effects in male
Reported by a physician from United States on 2012-07-09
Patient: male
Reactions: Face Oedema, Conjunctival Oedema, Skin Reaction, Rash Macular
Drug(s) suspected as cause:
Caprelsa
Possible Caprelsa side effects in 59 year old female
Reported by a physician from United States on 2012-07-09
Patient: 59 year old female, weighing 62.1 kg (136.6 pounds)
Reactions: Electrocardiogram QT Prolonged, Night Sweats, Headache, Rash, Flushing, Dysphonia, Diarrhoea, Palpitations, Hypertension
Drug(s) suspected as cause:
Caprelsa
Administration route: Oral
Start date: 2012-01-11
End date: 2012-06-07
Caprelsa
Administration route: Oral
Indication: Thyroid Cancer Stage IV
Start date: 2012-01-12
End date: 2012-03-08
Caprelsa
Administration route: Oral
Start date: 2012-04-04
Other drugs received by patient: Synthroid; Lomotil; Protonix; Vitamin B-12 CR
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