Index of reports
> Cases with Cytomegalovirus Infection (15)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Campath (Alemtuzumab) where reactions include cytomegalovirus infection. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Campath side effects in female
Reported by a consumer/non-health professional from Germany on 2012-07-06
Patient: female, weighing 70.0 kg (154.0 pounds)
Reactions: B-Cell Lymphoma, Anaemia, Urinary Incontinence, Abnormal Behaviour, Pulmonary Embolism, Cognitive Disorder, Pyrexia, Fall, Peripheral Sensory Neuropathy, Post Transplant Lymphoproliferative Disorder, Klebsiella Infection, Cytokine Release Syndrome, Cytomegalovirus Infection, Neutrophil Toxic Granulation Present, Traumatic Haematoma, Deep Vein Thrombosis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Campath
Dosage: 30 mg, bid
Start date: 2009-07-23
Campath
Dosage: 20 mg, qd
Start date: 2009-07-07
Campath
Dosage: 30 mg, qd
Start date: 2009-08-06
End date: 2009-08-06
Campath
Dosage: 30 mg, qd
Start date: 2009-09-11
End date: 2009-10-22
Campath
Dosage: 10 mg, qd
Indication: Peripheral T-Cell Lymphoma Unspecified
Start date: 2009-06-23
Cyclophosphamide
Dosage: 1200 mg, once
Start date: 2009-07-23
Cyclophosphamide
Dosage: 1200 mg, once
Start date: 2009-08-20
Cyclophosphamide
Dosage: 1200 mg, once
Start date: 2009-07-21
Cyclophosphamide
Dosage: 1250 mg, once
Indication: Peripheral T-Cell Lymphoma Unspecified
Start date: 2009-06-23
Cyclophosphamide
Dosage: 1200 mg, once
Start date: 2009-09-08
End date: 2009-09-08
Cyclophosphamide
Dosage: 1200 mg, once
Start date: 2009-07-07
Cyclophosphamide
Dosage: 1200 mg, once
Start date: 2009-08-06
End date: 2009-08-20
Doxorubicin HCL
Dosage: 80 mg, once
Start date: 2009-07-07
Doxorubicin HCL
Dosage: 80 mg, once
Indication: Peripheral T-Cell Lymphoma Unspecified
Start date: 2009-06-23
Doxorubicin HCL
Dosage: 80 mg, once
Start date: 2009-07-21
Doxorubicin HCL
Dosage: 80 mg, once
Start date: 2009-08-06
End date: 2009-08-20
Doxorubicin HCL
Dosage: 80 mg, once
Start date: 2009-09-08
End date: 2009-09-08
Doxorubicin HCL
Dosage: 80 mg, once
Start date: 2009-07-23
Doxorubicin HCL
Dosage: 80 mg, once
Start date: 2009-08-20
Filgrastim
Dosage: 3000 iu, unk
Start date: 2009-07-26
End date: 2009-08-27
Filgrastim
Dosage: unk on days 4 through 13 of course 5
Start date: 2009-08-20
Filgrastim
Dosage: unk on days 4 through 12 of course 6
Start date: 2009-09-08
Filgrastim
Dosage: unk on days 4, 5, 6 of course 1
Indication: Peripheral T-Cell Lymphoma Unspecified
Start date: 2009-06-23
Filgrastim
Dosage: unk on days 4 through 15 of course 2
Start date: 2009-07-07
Filgrastim
Dosage: unk on days 4 through 8 and day 13 of course 3
Start date: 2009-07-23
Filgrastim
Dosage: unk on days 6 + 7 and days 9 through 12 of course 4
Start date: 2009-08-06
Filgrastim
Dosage: 30000 iu, qd
Start date: 2009-09-11
End date: 2009-09-19
Prednisone
Dosage: 100 mg, qd for 5 days
Administration route: Oral
Start date: 2009-06-23
Prednisone
Dosage: 100 mg, qd for 5 days
Administration route: Oral
Start date: 2009-09-11
Prednisone
Dosage: 100 mg, qd for 5 days
Administration route: Oral
Start date: 2009-07-07
Prednisone
Dosage: 100 mg, qd for 5 days
Administration route: Oral
Indication: Peripheral T-Cell Lymphoma Unspecified
Start date: 2009-06-15
Prednisone
Dosage: 100 mg, qd for 5 days
Administration route: Oral
Start date: 2009-08-06
End date: 2009-08-10
Prednisone
Dosage: 100 mg, qd for 5 days
Administration route: Oral
Start date: 2009-07-23
Prednisone
Dosage: 100 mg, unk
Administration route: Oral
Start date: 2009-09-08
End date: 2009-09-08
Vincristine
Dosage: 2 mg, once
Start date: 2009-06-23
Vincristine
Dosage: 1 mg, once
Indication: Peripheral T-Cell Lymphoma Unspecified
Start date: 2009-06-15
Vincristine
Dosage: 2 mg, once
Start date: 2009-08-20
Vincristine
Dosage: 2 mg, once
Start date: 2009-07-23
Vincristine
Dosage: 2 mg, once
Start date: 2009-07-07
Vincristine
Dosage: 2 mg, once
Start date: 2009-07-21
Vincristine
Vincristine
Dosage: 2 mg, once
Start date: 2009-08-06
End date: 2009-08-20
Other drugs received by patient: Enoxaparin Sodium; Enoxaparin Sodium; Ganciclovir; Metoprolol Tartrate; Trimethoprim + Sulfamethoxazole; Dexamethasone; Antibiotics; Torsemide; Fluticasone Propionate W; Fondaparinux Sodium; Pantoprazole; Ganciclovir; Spiriva
Possible Campath side effects in female
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-28
Patient: female
Reactions: Cytomegalovirus Viraemia, Cytomegalovirus Infection, Peripheral Sensory Neuropathy, Pathogen Resistance
Drug(s) suspected as cause:
Campath
Dosage: on d8, 12 of admission
Indication: Transplant Rejection
Cidofovir
Dosage: received 3 doses
Indication: Cytomegalovirus Viraemia
Foscarnet
Indication: Cytomegalovirus Viraemia
Ganciclovir
Indication: Cytomegalovirus Viraemia
Leflunomide
Dosage: 20mg daily maintenance
Leflunomide
Dosage: 100mg daily for 3d; then 20mg daily
Indication: Cytomegalovirus Viraemia
Methylprednisolone
Dosage: 500mg daily
Indication: Transplant Rejection
Prednisolone
Administration route: Oral
Indication: Transplant Rejection
Tacrolimus
Indication: Immunosuppressant Drug Therapy
Valganciclovir
Dosage: 900mg daily for 5m
Administration route: Oral
Indication: Antiviral Prophylaxis
Valganciclovir
Administration route: Oral
Possible Campath side effects in 60 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-03-07
Patient: 60 year old male
Reactions: Graft Versus Host Disease, Tuberculosis, Pseudomembranous Colitis, Cytomegalovirus Infection, Epstein-Barr Viraemia, Pancytopenia, Lymphoma
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Campath
Dosage: unk
Indication: Acute Myeloid Leukaemia
Start date: 2011-07-29
End date: 2011-08-01
Campath
Dosage: unk
Start date: 2011-08-11
Certican
Dosage: 0.25 mg, bid
Administration route: Oral
Certican
Dosage: 0.5 mg, bid
Administration route: Oral
Indication: Acute Myeloid Leukaemia
Start date: 2011-06-01
End date: 2011-08-01
Mabthera
Dosage: unk
Indication: Acute Myeloid Leukaemia
Start date: 2011-07-01
End date: 2011-07-01
Mabthera
Dosage: unk
Myfortic
Indication: Immunosuppression
Myfortic
Dosage: 750 mg, tid
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-03-01
End date: 2011-06-01
Neoral
Dosage: 100 mg, qd
Indication: Immunosuppression
Neoral
Dosage: 160 mg, qd
Indication: Acute Myeloid Leukaemia
Start date: 2011-03-01
End date: 2011-06-01
Prograf
Dosage: unk
Indication: Graft Versus Host Disease in Skin
Possible Campath side effects in female
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-02-09
Patient: female
Reactions: Death, Pneumonia, Cytomegalovirus Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Fludara
Other drugs received by patient: Trimethoprim; Cyclosporine; Sulphamethoxazole; Anti-Thymocyte Globulin Equine NOS; Fluconazole; Acyclovir; Mycophenolate Mefetil; Busulfan; Corticosteroids
Possible Campath side effects in 68 year old female
Reported by a physician from Germany on 2012-02-06
Patient: 68 year old female
Reactions: Death, Pneumonia, Cytomegalovirus Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Dosage: unk
Indication: Haematological Malignancy
Fludara
Dosage: unk
Indication: Haematological Malignancy
Other drugs received by patient: Anti-Thymocyte Globulin Equine NOS; Sulphamethoxazole; Cyclosporine; Mycophenolate Mofetil; Trimethoprim; Fluconazole; Corticosteroids; Acyclovir; Busulfan
Possible Campath side effects in 68 year old
Reported by a physician from Germany on 2011-11-02
Patient: 68 year old
Reactions: Death, Bronchopulmonary Aspergillosis, Acute Graft Versus Host Disease, Cytomegalovirus Infection, Cerebral Toxoplasmosis
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Other drugs received by patient: Acyclovir; Trimethoprim; Carmustine; Cyclosporine; Melphalan Hydrochloride; Mycophenolate Mofetil; Anti-Thymocyte Globulin NOS; Sulphamethoxazole; Fludarabine; Fluconazole
Possible Campath side effects in 70 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-27
Patient: 70 year old male, weighing 67.9 kg (149.4 pounds)
Reactions: Dyspnoea, Anaemia, Muscular Weakness, Hypoaesthesia, Fall, Paraesthesia, Fatigue, Dehydration, Platelet Count Decreased, Cytomegalovirus Infection, Blood Pressure Decreased, Immobile, Infestation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
(Rituximab)
Dosage: 758 mg, not reported
Indication: Chronic Lymphocytic Leukaemia
Start date: 2010-12-27
End date: 2011-05-18
Campath
Dosage: 30 mg, tiw x 18 weeks, subcutaneous
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-07-29
End date: 2011-09-14
Cyclophosphamide
Dosage: 1212 mg
Indication: Chronic Lymphocytic Leukaemia
Start date: 2010-12-27
End date: 2011-05-18
Nipent
Dosage: 8 mg
Indication: Chronic Lymphocytic Leukaemia
Start date: 2010-12-27
End date: 2011-05-18
Possible Campath side effects in 55 year old
Reported by a physician from Germany on 2011-10-14
Patient: 55 year old
Reactions: Death, Bronchopulmonary Aspergillosis, Cytomegalovirus Infection, Systemic Inflammatory Response Syndrome
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Other drugs received by patient: Trimethoprim; Fludara; Sulphamethoxazole; Fluconazole; Cyclophosphamide; Mycophenolate Mofetil; Acyclovir; Cyclosporine
Possible Campath side effects in 48 year old
Reported by a physician from Germany on 2011-10-14
Patient: 48 year old
Reactions: Death, Bronchopulmonary Aspergillosis, Sepsis, Cytomegalovirus Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Other drugs received by patient: Sulphamethoxazole; Mycophenolate Mofetil; Cyclosporine; Trimethoprim; Fluconazole; Acyclovir; Corticosteroids; Busulfan; Cyclophosphamide
Possible Campath side effects in 42 year old
Reported by a physician from Germany on 2011-10-14
Patient: 42 year old
Reactions: Erythema Infectiosum, Acute Graft Versus Host Disease, Chronic Graft Versus Host Disease, Organising Pneumonia, Death, Cytomegalovirus Infection, Acute Respiratory Distress Syndrome, Systemic Inflammatory Response Syndrome, Pneumonia Respiratory Syncytial Viral
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Other drugs received by patient: Carmustine; Cyclosporine; Sulphamethoxazole; Fludara; Trimethoprim; Acyclovir; Melphalan Hydrochloride; Mycophenolate Mofetil; Fluconazole
Possible Campath side effects in 19 year old
Reported by a physician from Germany on 2011-10-14
Patient: 19 year old
Reactions: Pneumonia, Graft Versus Host Disease, Epidermolysis, Intestinal Haemorrhage, Death, Systemic Inflammatory Response Syndrome, Cytomegalovirus Infection, Escherichia Sepsis
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Other drugs received by patient: Cyclosporine; Mycophenolate Mofetil; Busulfan; Cyclophosphamide; Corticosteroids; Fluconazole; Anti-Thymocyte Globulin NOS; Daclizumab; Trimethoprim; Sulphamethoxazole; Acyclovir
Possible Campath side effects in 55 year old female
Reported by a physician from Germany on 2011-10-14
Patient: 55 year old female
Reactions: Death, Pneumonia, Cytomegalovirus Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Other drugs received by patient: Tacrolimus; Cyclosporine; Trimethoprim; Sulphamethoxazole; Mycophenolate Mofetil; Cyclophosphamide; Anti-Thymocyte Globulin NOS; Etanercept; Daclizumab; Fluconazole; Rituximab; Acyclovir; Corticosteroids
Possible Campath side effects in 68 year old
Reported by a physician from Germany on 2011-10-14
Patient: 68 year old
Reactions: Bronchopulmonary Aspergillosis, Death, Acute Graft Versus Host Disease, Cytomegalovirus Infection, Cerebral Toxoplasmosis
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Other drugs received by patient: Trimethoprim; Carmustine; Acyclovir; Melphalan Hydrochloride; Anti-Thymocyte Globulin NOS; Mycophenolate Mofetil; Sulphamethoxazole; Fludarabine Phosphate; Fluconazole; Cyclosporine
Possible Campath side effects in 68 year old female
Reported by a physician from Germany on 2011-10-13
Patient: 68 year old female
Reactions: Death, Pneumonia, Cytomegalovirus Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Other drugs received by patient: Busulfan; Cyclosporine; Fluconazole; Acyclovir; Mycophenolate Mofetil; Sulphamethoxazole; Corticosteroids; Fludara; Anti-Thymocyte Globulin NOS; Trimethoprim
Possible Campath side effects in 37 year old
Reported by a physician from Germany on 2011-10-13
Patient: 37 year old
Reactions: Death, Pneumonia, Sepsis, Cytomegalovirus Infection, Chronic Graft Versus Host Disease, Liver Transplant
Adverse event resulted in: death
Drug(s) suspected as cause:
Campath
Other drugs received by patient: Mycophenolate Mofetil; Sulfamethoxazole W; Acyclovir; Busulfan; Anti-Thymocyte Globulin NOS; Cyclophosphamide; Fluconazole; Cyclosporine
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