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Bumetanide (Bumetanide) - Side Effect Reports to FDA

 
 



This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Bumetanide and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.

Reports by Event Outcome

All Cases (113)
Death (44)
Life Threatening Events (5)
Disability (2)

Reports by Reaction Type

Renal Failure Acute (35)Blood Creatinine Increased (27)Atrial Fibrillation (25)Fluid Overload (24)Toxic Epidermal Necrolysis (24)Haemoglobin Decreased (23)Stevens-Johnson Syndrome (21)Oedema Peripheral (20)DRY Skin (19)Pruritus (18)Erythema (18)Completed Suicide (18)

Below are a few examples of reports where side effects / adverse reactions may be related to Bumetanide. For a complete list or a specific selection of reports, please use the links above.

Possible Bumetanide side effects in male

Reported by a physician from Netherlands on 2012-08-24

Patient: male, weighing 82.8 kg (182.2 pounds)

Reactions: Renal Disorder, Cardiac Failure

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bumetanide
    Dosage: 3 mg, tid
    Administration route: Oral
    Indication: Cardiac Failure
    Start date: 2012-07-14
    End date: 2012-08-21

Enalapril Maleate
    Dosage: unk
    Administration route: Oral
    Indication: Cardiac Failure
    Start date: 2009-11-10
    End date: 2012-07-11

Other drugs received by patient: Spironolactone; Bumetanide; Spironolactone; Metoprolol Tartrate; Metoprolol Tartrate; Spironolactone



Possible Bumetanide side effects in

Reported by a pharmacist from United Kingdom on 2012-08-23

Patient:

Reactions: Pruritus, Hypersensitivity, Pain, Scab, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Stevens-Johnson Syndrome, Blister, Renal Failure Acute, Fluid Overload, Rash Generalised, Atrial Fibrillation, Toxic Epidermal Necrolysis, DRY Skin, Haemoglobin Decreased, Exfoliative Rash, Swelling, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide

Clarithromycin
    Dosage: 500 mg, bid
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Spironolactone

Zocor
    Administration route: Oral

Other drugs received by patient: Amiodarone HCL; Amoxicillin and Clavulanate Potassium; Furosemide; Methotrexate; Adenosine; Dioralyte; Fortisip; Heparin; Omeprazole; Adcal-D3; Teicoplanin; Warfarin Sodium; Dalteparin Sodium; Diclofenac Diethylamine; Folic Acid; Gentamicin; Metoclopramide; Bisoprolol Fumarate; Candesartan Cilexetil; Acetaminophen and Codeine Phosphate; Clotrimazole; Acetaminophen; Tramadol Hydrochloride



Possible Bumetanide side effects in 82 year old female

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-08-23

Patient: 82 year old female

Reactions: Renal Failure, Vomiting, Nausea, Dehydration, Constipation, Decreased Appetite, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bumetanide
    Dosage: 1 mg, bid

Esidrix
    Dosage: 25 mg, unk
    End date: 2012-07-23

Metformin HCL
    Dosage: 500 mg, daily



Possible Bumetanide side effects in 82 year old female

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-08-23

Patient: 82 year old female

Reactions: Renal Failure, Dehydration, Constipation, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bumetanide
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Esidrix
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-07-23

Metformin HCL
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Simvastatin; Digimerck Pico 0,05; Ventolin; Spiriva; Fluticasone Propionate / Salmeterol; Warfarin Sodium



Possible Bumetanide side effects in male

Reported by a physician from Netherlands on 2012-08-22

Patient: male, weighing 82.8 kg (182.2 pounds)

Reactions: Renal Disorder, Cardiac Failure

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bumetanide

Enalapril Maleate
    Dosage: unk
    Administration route: Oral
    Indication: Cardiac Failure
    Start date: 2009-11-10
    End date: 2012-07-11

Other drugs received by patient: Spironolactone; Bumetanide; Metoprolol Tartrate



Possible Bumetanide side effects in 80 year old female

Reported by a physician from Germany on 2012-08-22

Patient: 80 year old female

Reactions: Dehydration, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bumetanide
    Administration route: Oral

Esidrix
    Administration route: Oral
    End date: 2012-07-23

Metformin HCL
    Administration route: Oral

Other drugs received by patient: Digitoxin TAB; Simvastatin; Warfarin Sodium; Ventolin; Spiriva; Fluticasone Propionate / Salmeterol



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-08-21

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Hypersensitivity, Pruritus, Pain, Scab, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Blister, Stevens-Johnson Syndrome, Renal Failure Acute, Fluid Overload, Rash Generalised, Atrial Fibrillation, Toxic Epidermal Necrolysis, DRY Skin, Haemoglobin Decreased, Exfoliative Rash, Swelling, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide
    Dosage: unk

Clarithromycin
    Dosage: 500 mg, 2x/day
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Spironolactone
    Dosage: unk

Zocor
    Dosage: unk
    Administration route: Oral

Other drugs received by patient: Amiodarone HCL; Diclofenac Diethylammonium Salt; Gentamicin; Adenosine; Furosemide; Candesartan Cilexetil; Amoxicillin and Clavulanate Potassium; Bisoprolol Fumarate; Adcal-D3; Dalteparin Sodium; Heparin; Clotrimazole; Fortisip; Omeprazole; Teicoplanin; Methotrexate; Folic Acid; Acetaminophen and Codeine Phosphate; Dioralyte; Metoclopramide; Tramadol HCL; Warfarin Sodium; Paracetamol



Possible Bumetanide side effects in male

Reported by a physician from France on 2012-08-20

Patient: male

Reactions: Diabetes Mellitus

Drug(s) suspected as cause:
Bumetanide
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-02-28
    End date: 2012-03-06

Cellcept
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-02-27

Mabthera
    Indication: Product Used FOR Unknown Indication

Prednisone TAB
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-03-04
    End date: 2012-03-09

Prednisone TAB
    Start date: 2012-03-10
    End date: 2012-03-23

Prograf
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-02-27

Solu-Medrol
    Start date: 2012-03-01
    End date: 2012-03-03

Solu-Medrol
    Start date: 2012-02-28

Solu-Medrol
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-02-27

Other drugs received by patient: Irbesartan; Flixotide 250; Rosuvastatin



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-08-20

Patient: 79 year old female, weighing 55.4 kg (121.9 pounds)

Reactions: Pruritus, Pulmonary Embolism, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Blister, Toxic Epidermal Necrolysis, Skin Tightness, Staphylococcal Scalded Skin Syndrome, Exfoliative Rash, Vasculitis, Rash Maculo-Papular, Hypersensitivity, Skin Exfoliation, Scab, Adverse Drug Reaction, Pain, Petechiae, Skin Swelling, Stevens-Johnson Syndrome, Renal Failure Acute, Fluid Overload, Rash Generalised, Atrial Fibrillation, DRY Skin, Rash, Pulmonary Fibrosis, Skin Irritation, Mucosal Erosion, Haemoglobin Decreased, Diarrhoea, Skin Erosion

Adverse event resulted in: death

Drug(s) suspected as cause:
Amiodarone HCL
    Indication: Product Used FOR Unknown Indication

Amoxicillin
    Indication: Product Used FOR Unknown Indication

Bumetanide
    Indication: Product Used FOR Unknown Indication

Clarithromycin
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Methotrexate
    Indication: Product Used FOR Unknown Indication

Simvastatin
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Dalteparin Sodium; Candesartan Cilexetil; Bisoprolol Fumarate; Bisoprolol Fumarate; Clotrimazole; Fortisip; Diclofenac Diethylammonium Salt; Adenosine; Furosemide; Acetaminophen; Tramadol HCL; Acetaminophen and Codeine Phosphate; Teicoplanin; Adcal-D3; Dioralyte; Gentamicin; Amoxicillin and Clavulanate Potassium; Heparin; Folic Acid; Omeprazole; Metoclopramide



Possible Bumetanide side effects in 56 year old male

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: 56 year old male, weighing 117.0 kg (257.4 pounds)

Reactions: Weight Increased, Drug Ineffective, Fluid Retention

Drug(s) suspected as cause:
Advil
    Indication: Arthralgia

Advil
    Indication: Back Pain

Advil
    Dosage: 400 mg, 2x/day
    Administration route: Oral
    Indication: Pain in Extremity
    Start date: 2011-01-01
    End date: 2012-08-15

Bumetanide
    Dosage: unk

Lasix
    Dosage: unk



Possible Bumetanide side effects in 79 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-17

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Pruritus, Hypersensitivity, Scab, Pain, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Stevens-Johnson Syndrome, Renal Failure Acute, Blister, Fluid Overload, Rash Generalised, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Haemoglobin Decreased, Exfoliative Rash, Swelling, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide
    Indication: Product Used FOR Unknown Indication

Clarithromycin
    Dosage: 500 mg, bid
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Spironolactone
    Indication: Product Used FOR Unknown Indication

Zocor
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Gentamicin; Heparin; Metoclopramide; Methotrexate; Dioralyte / 00386201 /; Candesartan Cilexetil; Amiodarone; Diclofenac Diethylamine; Warfarin Sodium; Amoxicillin and Clavulanate Potassium; Fortisip; Dalteparin Sodium; Bisoprolol; Tramadol HCL; Omeprazole; Furosemide; Adcal D3; Acetaminophen and Codeine Phosphate; Adenosine; Teicoplanin; Acetaminophen; Clotrimazole; Folic Acid



Possible Bumetanide side effects in 82 year old female

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-08-17

Patient: 82 year old female

Reactions: Vomiting, Renal Failure, Nausea, Dehydration, Constipation, Hypokalaemia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bumetanide
    Dosage: 1 mg, bid

Esidrix
    Dosage: 25 mg, unk
    End date: 2012-07-23

Metformin HCL
    Dosage: 500 mg, daily



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-08-17

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Hypersensitivity, Pruritus, Pain, Scab, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Blister, Renal Failure Acute, Stevens-Johnson Syndrome, Fluid Overload, Rash Generalised, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Haemoglobin Decreased, Exfoliative Rash, Swelling, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide
    Dosage: unk

Clarithromycin
    Dosage: 500 mg, 2x/day
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Spironolactone
    Dosage: unk

Zocor
    Dosage: unk
    Administration route: Oral

Other drugs received by patient: Candesartan Cilexetil; Bisoprolol; Fortisip; Folic Acid; Diclofenac Diethylammonium Salt; Amiodarone; Tramadol HCL; Dioralyte; Gentamicin; Dalteparin Sodium; Clotrimazole; Amoxicillin and Clavulanate Potassium; Metoclopramide; Acetaminophen and Codeine Phosphate; Warfarin Sodium; Adenosine; Teicoplanin; Heparin; Acetaminophen; Omeprazole; Furosemide; Paracetamol; Methotrexate; Adcal-D3



Possible Bumetanide side effects in 79 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-16

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Pruritus, Hypersensitivity, Scab, Pain, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Renal Failure Acute, Blister, Stevens-Johnson Syndrome, Fluid Overload, Rash Generalised, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Haemoglobin Decreased, Exfoliative Rash, Swelling, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Clarithromycin
    Dosage: 500 mg, bid
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Spironolactone
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Zocor
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Methotrexate; Teicoplanin; Amiodarone; Folic Acid; Heparin; Adcal-D3; Bisoprolol; Clotrimazole; Codeine Phosphate and Acetaminophen; Acetaminophen; Dioralyte; Fortisip; Candesartan Cilexetil; Diclofenac Diethylammonium Salt; Gentamicin; Metoclopramide; Omeprazole; Tramadol HCL; Adenosine; Amoxicillin and Clavulanate Potassium; Dalteparin Sodium; Furosemide; Warfarin Sodium



Possible Bumetanide side effects in 79 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-14

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Haemoglobin Decreased, Fluid Overload, Toxic Epidermal Necrolysis, Atrial Fibrillation, Renal Failure Acute, Pulmonary Fibrosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Bumetanide

Clarithromycin
    Dosage: 500mg, bid
    Administration route: Oral
    Start date: 2012-05-12
    End date: 2012-05-21

Methotrexate
    Dosage: stopped on admission. pulmonary fibrosis secondary to methotrexate and fluid overload.

Spironolactone

Zocor
    Administration route: Oral

Other drugs received by patient: Clotrimazole; Tramadol HCL; Dalteparin Sodium; Diclofenac Diethylamine; Adcal-D3; Candesartan Cilexetil; Acetaminophen; Fortisip; Adenosine; Folic Acid; Bisoprolol; Dioralyte; Heparin; Amiodarone HCL; Furosemide; Metoclopramide; Acetaminophen and Codeine Phosphate; Warfarin Sodium; Acetaminophen W / Codeine; Omeprazole; Gentamicin; Amoxicillin and Clavulanate Potassium; Teicoplanin



Possible Bumetanide side effects in 64 year old female

Reported by a consumer/non-health professional from United Kingdom on 2012-08-14

Patient: 64 year old female, weighing 99.3 kg (218.5 pounds)

Reactions: Atrial Fibrillation

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Bumetanide

Other drugs received by patient: Omeprazole; Flecainide Acetate; Levothyroxine Sodium; Bisoprolol



Possible Bumetanide side effects in 90 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: 90 year old male, weighing 58.1 kg (127.8 pounds)

Reactions: Contusion, Vomiting, Nausea, Dehydration, Memory Impairment, Fall

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Acetaminophen / Hydrocodone Bitartrate
    Dosage: 500/5 mg tid po
    Administration route: Oral
    Indication: Pain
    Start date: 2012-07-30
    End date: 2012-08-01

Bumetanide
    Dosage: 1 mg bid po
    Administration route: Oral
    Indication: Hypertension
    Start date: 2011-11-04
    End date: 2012-08-01



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-08-13

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Hypersensitivity, Pruritus, Pain, Scab, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Renal Failure Acute, Stevens-Johnson Syndrome, Blister, Fluid Overload, Rash Generalised, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Haemoglobin Decreased, Exfoliative Rash, Swelling, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide
    Dosage: unk

Clarithromycin
    Dosage: 500 mg, 2x/day
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Spironolactone
    Dosage: unk

Zocor
    Dosage: unk
    Administration route: Oral

Other drugs received by patient: Paracetamol; Clotrimazole; Gentamicin; Adenosine; Amoxicillin and Clavulanate Potassium; Tramadol HCL; Acetaminophen; Furosemide; Candesartan Cilexetil; Metoclopramide; Adcal-D3; Diclofenac Diethylammonium Salt; Omeprazole; Dalteparin Sodium; Teicoplanin; Heparin; Fortisip; Methotrexate; Folic Acid; Warfarin Sodium; Bisoprolol; Amiodarone HCL; Acetaminophen and Codeine Phosphate; Dioralyte



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-08-10

Patient: 79 year old female

Reactions: Pruritus, Hypersensitivity, Pain, Scab, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Blister, Stevens-Johnson Syndrome, Renal Failure Acute, Fluid Overload, Rash Generalised, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Haemoglobin Decreased, Swelling, Exfoliative Rash, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide

Clarithromycin
    Dosage: 500 mg, bid
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Spironolactone

Zocor
    Administration route: Oral

Other drugs received by patient: Adenosine; Candesartan Cilexetil; Amoxicillin and Clavulanate Potassium; Tramadol HCL; Bisoprolol Fumarate; Dioralyte; Heparin; Omeprazole; Amiodarone HCL; Codeine Phosphate and Acetaminophen; Teicoplanin; Diclofenac Diethylamine; Fortisip; Metoclopramide; Furosemide; Methotrexate; Clotrimazole; Dalteparin Sodium; Folic Acid; Adcal-D3; Gentamicin; Acetaminophen; Warfarin Sodium



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-08-09

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Pruritus, Hypersensitivity, Scab, Pain, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Stevens-Johnson Syndrome, Renal Failure Acute, Blister, Fluid Overload, Rash Generalised, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Haemoglobin Decreased, Swelling, Exfoliative Rash, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide
    Dosage: unk

Clarithromycin
    Dosage: 500 mg, 2x/day
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Spironolactone
    Dosage: unk

Zocor
    Dosage: unk
    Administration route: Oral

Other drugs received by patient: Adenosine; Candesartan Cilexetil; Bisoprolol Fumarate; Amiodarone HCL; Warfarin Sodium; Clotrimazole; Acetaminophen and Codeine Phosphate; Gentamicin; Omeprazole; Folic Acid; Dioralyte; Diclofenac Diethylammonium Salt; Paracetamol; Adcal-D3; Acetaminophen; Furosemide; Fortisip; Tramadol HCL; Dalteparin Sodium; Teicoplanin; Metoclopramide; Amoxicillin and Clavulanate Potassium; Heparin; Methotrexate



Possible Bumetanide side effects in male

Reported by a physician from Netherlands on 2012-08-08

Patient: male, weighing 80.0 kg (176.0 pounds)

Reactions: Dehydration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Blinded Aliskiren
    Dosage: code not broken
    Administration route: Oral
    Indication: Cardiovascular Disorder
    Start date: 2008-05-21
    End date: 2011-12-27

Blinded Aliskiren
    Dosage: code not broken
    Administration route: Oral

Blinded NO Treatment Received
    Dosage: code not broken
    Administration route: Oral

Blinded NO Treatment Received
    Dosage: code not broken
    Administration route: Oral
    Indication: Cardiovascular Disorder
    Start date: 2008-05-21
    End date: 2011-12-27

Bumetanide
    Dosage: 1 mg, qd

Bumetanide
    Dosage: 1 mg, bid
    Indication: Cardiac Failure
    Start date: 2011-10-05
    End date: 2012-07-18

Placebo
    Dosage: code not broken
    Administration route: Oral
    Indication: Cardiovascular Disorder
    Start date: 2008-05-21
    End date: 2011-12-27

Placebo
    Dosage: code not broken
    Administration route: Oral

Other drugs received by patient: Diovan



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-08-06

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Hypersensitivity, Pruritus, Scab, Pain, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Feeling Hot, Renal Failure Acute, Stevens-Johnson Syndrome, Blister, Fluid Overload, Rash Generalised, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Pulmonary Fibrosis, Haemoglobin Decreased, Swelling, Exfoliative Rash, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide

Clarithromycin
    Dosage: 500 mg, bid
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Methotrexate

Spironolactone

Zocor
    Administration route: Oral

Other drugs received by patient: Amiodarone HCL; Acetaminophen; Clotrimazole; Folic Acid; Fortisip; Heparin; Tramadol HCL; Warfarin Sodium; Diclofenac Sodium; Adcal-D3; Bisoprolol Fumarate; Acetaminophen and Codeine Phosphate; Dalteparin Sodium; Omeprazole; Candesartan Cilexetil; Gentamicin; Adenosine; Furosemide; Metoclopramide; Amoxicillin and Clavulanate Potassium; Dioralyte; Teicoplanin



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-08-06

Patient: 79 year old female, weighing 55.4 kg (121.9 pounds)

Reactions: Pruritus, Pulmonary Embolism, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Blister, Toxic Epidermal Necrolysis, Skin Tightness, Exfoliative Rash, Staphylococcal Scalded Skin Syndrome, Vasculitis, Rash Maculo-Papular, Hypersensitivity, Skin Exfoliation, Pain, Scab, Adverse Drug Reaction, Petechiae, Skin Swelling, Stevens-Johnson Syndrome, Renal Failure Acute, Fluid Overload, Rash Generalised, Atrial Fibrillation, Rash, DRY Skin, Skin Irritation, Pulmonary Fibrosis, Haemoglobin Decreased, Mucosal Erosion, Diarrhoea, Skin Erosion

Adverse event resulted in: death

Drug(s) suspected as cause:
Amiodarone HCL
    Indication: Product Used FOR Unknown Indication

Amoxicillin
    Indication: Product Used FOR Unknown Indication

Bumetanide
    Indication: Product Used FOR Unknown Indication

Clarithromycin
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Methotrexate
    Indication: Product Used FOR Unknown Indication

Simvastatin
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Candesartan Cilexetil; Clotrimazole; Gentamicin; Omeprazole; Adenosine; Fortisip; Adcal-D3; Dioralyte; Dalteparin Sodium; Bisoprolol Fumarate; Bisoprolol Fumarate; Acetaminophen and Codeine Phosphate; Diclofenac Diethylammonium Salt; Amoxicillin and Clavulanate Potassium; Heparin; Metoclopramide; Teicoplanin; Furosemide; Acetaminophen; Folic Acid; Tramadol HCL



Possible Bumetanide side effects in 64 year old male

Reported by a pharmacist from United States on 2012-07-30

Patient: 64 year old male, weighing 118.6 kg (260.9 pounds)

Reactions: Hyponatraemia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bumetanide
    Dosage: 2 mg bid po
    Administration route: Oral
    Indication: Polyuria
    Start date: 2010-10-31
    End date: 2012-07-24

Metolazone
    Dosage: 5 mg other po
    Administration route: Oral
    Indication: Polyuria
    Start date: 2012-07-05
    End date: 2012-07-24



Possible Bumetanide side effects in male

Reported by a physician from Netherlands on 2012-07-27

Patient: male, weighing 80.0 kg (176.0 pounds)

Reactions: Malaise

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Blinded Aliskiren
    Dosage: code not broken
    Administration route: Oral
    Indication: Cardiovascular Disorder
    Start date: 2008-05-21
    End date: 2011-12-27

Blinded NO Treatment Received
    Dosage: code not broken
    Administration route: Oral
    Indication: Cardiovascular Disorder
    Start date: 2008-05-21
    End date: 2011-12-27

Bumetanide
    Dosage: 2 mg, bid
    Start date: 2011-10-05
    End date: 2012-07-18

Placebo
    Dosage: code not broken
    Administration route: Oral
    Indication: Cardiovascular Disorder
    Start date: 2008-05-21
    End date: 2011-12-27

Other drugs received by patient: Diovan



Possible Bumetanide side effects in 79 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-26

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Pruritus, Hypersensitivity, Scab, Pain, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Blister, Stevens-Johnson Syndrome, Renal Failure Acute, Fluid Overload, Rash Generalised, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Haemoglobin Decreased, Swelling, Exfoliative Rash, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide
    Indication: Product Used FOR Unknown Indication

Clarithromycin
    Dosage: 500 mg, bid
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Simvastatin
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Furosemide; Acetaminophen and Codeine Phosphate; Acetaminophen; Diclofenac Diethylamine; Adenosine; Amoxicillin and Clavulanate Potassium; Bisoprolol Fumarate; Metoclopramide; Methotrexate; Tramadol Hydrochloride; Clotrimazole; Folic Acid; Adcal D3; Dioralyte / 00386201 /; Warfarin Sodium; Omeprazole; Dalteparin Sodium; Teicoplanin; Fortisip; Gentamicin; Candesartan; Amiodarone Hydrochloride; Heparin



Possible Bumetanide side effects in

Reported by a pharmacist from United Kingdom on 2012-07-26

Patient:

Reactions: Pruritus, Hypersensitivity, Scab, Pain, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Renal Failure Acute, Blister, Stevens-Johnson Syndrome, Fluid Overload, Rash Generalised, Atrial Fibrillation, Toxic Epidermal Necrolysis, DRY Skin, Haemoglobin Decreased, Exfoliative Rash, Swelling, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide

Clarithromycin
    Dosage: 500 mg, bid
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Spironolactone

Zocor
    Administration route: Oral

Other drugs received by patient: Tramadol HCL; Amoxicillin and Clavulanate Potassium; Fortisip; Methotrexate; Adenosine; Omeprazole; Bisoprolol Fumarate; Teicoplanin; Warfarin Sodium; Furosemide; Amiodarone Hydrochloride; Folic Acid; Metoclopramide; Adcal-D3; Candesartan; Dioralyte; Acetaminophen; Clotrimazole; Acetaminophen and Codeine Phosphate; Dalteparin Sodium; Diclofenac Diethylamine; Gentamicin; Heparin



Possible Bumetanide side effects in 79 year old female

Reported by a consumer/non-health professional from United Kingdom on 2012-07-25

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Fluid Overload, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Haemoglobin Decreased, Oedema Peripheral, Stevens-Johnson Syndrome, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Bumetanide
    Indication: Product Used FOR Unknown Indication

Clarithromycin
    Dosage: 1000 mg (500 mg,2 in 1 d),oral
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Simvastatin
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Acetaminophen and Codeine Phosphate; Tramadol HCL; FAT + Protein (Fortsip); Amiodarone HCL; Metoclopramide; Acetaminophen; Teicoplanin; Warfarin Sodium; Candesartan Cilexetil; Clotrimazole; Dioralyte; Folic Acid; Furosemide; Methotrexate; Diclofenac (Diclofenac Diethylammonium Salt); Heparin; Adcal-D3; Adenosine; Bisoprolol Fumarate; Amoxycillin + Potassium Clavulanate (CO-Amoxiclav); Dalteparin (Dalteparin Sodium); Gemtamicin; Omeprazole



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-07-25

Patient: 79 year old female, weighing 55.5 kg (122.1 pounds)

Reactions: Haemoglobin Decreased, Fluid Overload, Toxic Epidermal Necrolysis, Atrial Fibrillation, Pulmonary Fibrosis, Stevens-Johnson Syndrome, Renal Failure Acute

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide
    Indication: Product Used FOR Unknown Indication

Clarithromycin
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Methotrexate
    Indication: Product Used FOR Unknown Indication

Simvastatin
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Clotrimazole; Dioralyte / 00386201 /; Folic Acid; Metoclopramide; Adcal D3; Gentamicin; Adenosine; Amiodarone Hydrochloride; Dalteparin Sodium; Omeprazole; Tramadol Hydrochloride; Acetaminophen and Codeine Phosphate; Teicoplanin; Candesartan; Amoxicillin and Clavulanate Potassium; Fortisip; Furosemide; Bisoprolol Fumarate; Heparin; Acetaminophen; Diclofenac; Warfarin Sodium



Possible Bumetanide side effects in 79 year old female

Reported by a pharmacist from United Kingdom on 2012-07-25

Patient: 79 year old female, weighing 55.5 kg (122.0 pounds)

Reactions: Hypersensitivity, Pruritus, Pain, Scab, Petechiae, Eczema, Erythema, Rash Pruritic, Oedema Peripheral, Blood Creatinine Increased, Blister, Stevens-Johnson Syndrome, Renal Failure Acute, Fluid Overload, Rash Generalised, Toxic Epidermal Necrolysis, Atrial Fibrillation, DRY Skin, Haemoglobin Decreased, Exfoliative Rash, Swelling, Rash Maculo-Papular

Adverse event resulted in: death

Drug(s) suspected as cause:
Bumetanide
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Clarithromycin
    Dosage: 500 mg, bid
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-05-12
    End date: 2012-05-21

Simvastatin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Amiodarone Hydrochloride; Dioralyte; Furosemide; Acetaminophen; Acetaminophen and Codeine Phosphate; Teicoplanin; Warfarin Sodium; Adcal-D3; Clotrimazole; Diclofenac Diethylammonium Salt; Fortisip; Omeprazole; Candesartan; Dalteparin Sodium; Methotrexate; Metoclopramide; Adenosine; Bisoprolol Fumarate; Amoxicillin and Clavulanate Potassium; Tramadol Hydrochloride; Folic Acid; Gentamicin; Heparin

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