Index of reports
> Cases with Agranulocytosis (11)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Azulfidine (Sulfasalazine) where reactions include agranulocytosis. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Azulfidine side effects in male
Reported by a physician from Japan on 2012-07-18
Patient: male, weighing 55.0 kg (121.0 pounds)
Reactions: Agranulocytosis, Histiocytosis Haematophagic, Pseudomonal Sepsis, Disseminated Intravascular Coagulation, Cytomegalovirus Infection, Deep Vein Thrombosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Azulfidine
Dosage: 1000 mg, 1x/day
Administration route: Oral
Indication: Sjogren's Syndrome
Start date: 2012-03-29
End date: 2012-04-17
Azulfidine
Indication: Arthropathy
Azulfidine
Dosage: 500 mg, 1x/day
Administration route: Oral
Indication: Scleroderma
Start date: 2012-03-14
End date: 2012-03-28
Other drugs received by patient: Actos; Rabeprazole Sodium; Lobu; Prednisolone
Possible Azulfidine side effects in 59 year old female
Reported by a pharmacist from Japan on 2012-07-16
Patient: 59 year old female, weighing 64.8 kg (142.6 pounds)
Reactions: Drug Eruption, Hepatic Function Abnormal, Oesophagitis Ulcerative, Febrile Neutropenia, Agranulocytosis, RED Blood Cell Count Decreased, Arthralgia, Oral Candidiasis, Herpes Oesophagitis, Abscess Limb
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Azulfidine
Dosage: 500 mg/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2011-10-01
End date: 2011-11-05
Celebrex
Dosage: 200 mg, 2x/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2011-10-01
End date: 2011-11-04
Other drugs received by patient: Prednisolone; Prednisolone
Possible Azulfidine side effects in 59 year old female
Reported by a pharmacist from Japan on 2012-07-05
Patient: 59 year old female, weighing 64.8 kg (142.6 pounds)
Reactions: Drug Eruption, Hepatic Function Abnormal, Febrile Neutropenia, Oesophagitis Ulcerative, Agranulocytosis, Oral Candidiasis, RED Blood Cell Count Decreased, Arthralgia, Herpes Oesophagitis, Abscess Limb
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Azulfidine
Dosage: 500 mg/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2011-10-01
End date: 2011-11-05
Celebrex
Dosage: 200 mg, 2x/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2011-10-01
End date: 2011-11-04
Other drugs received by patient: Prednisolone Sodium Succinate INJ; Prednisolone Sodium Succinate INJ
Possible Azulfidine side effects in 59 year old female
Reported by a physician from Japan on 2012-06-04
Patient: 59 year old female, weighing 64.8 kg (142.6 pounds)
Reactions: Drug Eruption, Hepatic Function Abnormal, Febrile Neutropenia, Oesophagitis Ulcerative, Agranulocytosis, Oral Candidiasis, Arthralgia, RED Blood Cell Count Decreased, Herpes Oesophagitis, Abscess Limb
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Azulfidine
Dosage: 500 mg/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2011-10-01
End date: 2011-11-05
Celebrex
Dosage: 200 mg, 2x/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2011-10-01
End date: 2011-11-04
Other drugs received by patient: Prednisolone; Prednisolone
Possible Azulfidine side effects in 59 year old female
Reported by a pharmacist from Japan on 2012-05-25
Patient: 59 year old female, weighing 64.8 kg (142.6 pounds)
Reactions: Drug Eruption, Hepatic Function Abnormal, Effusion, Oesophagitis Ulcerative, Oropharyngeal Pain, Malaise, RED Blood Cell Count Decreased, Gamma-Glutamyltransferase Increased, Oral Candidiasis, Abscess Limb, Blood Alkaline Phosphatase Increased, Blood Lactate Dehydrogenase Increased, Alanine Aminotransferase Increased, Febrile Neutropenia, Agranulocytosis, Arthralgia, Aspartate Aminotransferase Increased, Herpes Oesophagitis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Azulfidine
Dosage: 500 mg/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2011-10-01
End date: 2011-11-05
Celebrex
Dosage: 200 mg, 2x/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2011-10-01
End date: 2011-11-04
Other drugs received by patient: Prednisolone; Prednisolone
Possible Azulfidine side effects in 66 year old male
Reported by a physician from Japan on 2012-05-15
Patient: 66 year old male, weighing 69.0 kg (151.8 pounds)
Reactions: Agranulocytosis, Pyelonephritis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Azulfidine
Dosage: 500 mg, 2x/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2012-01-12
End date: 2012-02-23
Lansoprazole
Dosage: 15 mg, 1x/day
Administration route: Oral
Start date: 2012-01-12
End date: 2012-02-23
Other drugs received by patient: Amlodipine; Rebamipide; Famotidine; Propiverine Hydrochloride; Glimepiride; Loxonin; Pursennid; Sitagliptin Phosphate; Azelastine Hydrochloride
Possible Azulfidine side effects in 60 year old male
Reported by a physician from Japan on 2012-04-30
Patient: 60 year old male
Reactions: Agranulocytosis, Disseminated Intravascular Coagulation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Azulfidine
Indication: Sjogren's Syndrome
Azulfidine
Indication: Arthropathy
Azulfidine
Dosage: 1 g/day
Administration route: Oral
Indication: Scleroderma
Start date: 2012-03-14
Possible Azulfidine side effects in 66 year old male
Reported by a physician from Japan on 2012-04-27
Patient: 66 year old male, weighing 69.0 kg (151.8 pounds)
Reactions: Agranulocytosis, Pyelonephritis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Lansoprazole
Dosage: 15 mg, 1x/day
Administration route: Oral
Start date: 2012-01-12
End date: 2012-02-23
Azulfidine
Dosage: 500 mg, 2x/day
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2012-01-12
End date: 2012-02-23
Other drugs received by patient: Propiverine Hydrochloride; Glimepiride; Azelastine Hydrochloride; Pursennid; Rebamipide; Amlodipine; Famotidine; Sitagliptin Phosphate; Loxonin
Possible Azulfidine side effects in 78 year old male
Reported by a physician from Japan on 2011-10-28
Patient: 78 year old male
Reactions: Agranulocytosis, Sepsis
Adverse event resulted in: death
Drug(s) suspected as cause:
Azulfidine
Possible Azulfidine side effects in 78 year old male
Reported by a physician from Japan on 2011-10-11
Patient: 78 year old male
Reactions: Agranulocytosis, Sepsis
Adverse event resulted in: death
Drug(s) suspected as cause:
Azulfidine
Possible Azulfidine side effects in 78 year old male
Reported by a physician from Japan on 2011-10-11
Patient: 78 year old male, weighing 60.2 kg (132.4 pounds)
Reactions: Disseminated Intravascular Coagulation, Oropharyngeal Pain, Pyrexia, Chest X-RAY Abnormal, Agranulocytosis, Corynebacterium Test Positive, Sepsis, Septic Shock, Leukopenia
Adverse event resulted in: death
Drug(s) suspected as cause:
Azulfidine
Dosage: 500 mg daily
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2010-03-04
Azulfidine
Dosage: 500 mg, 2x/day
Start date: 2010-03-11
End date: 2010-04-19
Other drugs received by patient: Olmesartan Medoxomil; Calblock; Insulin Detemir; Aspirin; Lansoprazole; Glufast; Montelukast Sodium; Alendronate Sodium; Prednisolone
|