Index of reports
> Life Threatening Events (302)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Avastin (Bevacizumab) life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.
Reports 1 - 30 of 302 Next >>
Possible Avastin side effects in female
Reported by a physician from Canada on 2012-08-27
Patient: female, weighing 86.0 kg (189.2 pounds)
Reactions: Angina Unstable, Proteinuria
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Indication: Product Used FOR Unknown Indication
Lucentis
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Metoprolol Tartrate; Risedronate Sodium; Diovan; Lansoprazole; Novolin 70 / 30; Plavix; Lipitor; Amlodipine; Gabapentin; Calcium Carbonate
Possible Avastin side effects in male
Reported by a physician from Lebanon on 2012-08-23
Patient: male, weighing 74.5 kg (163.9 pounds)
Reactions: Abscess Neck, Pharyngeal Fistula, Disseminated Intravascular Coagulation, Vascular Pseudoaneurysm, Pharyngeal Ulceration, Septic Shock, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Other drugs received by patient: Fluorouracil; Oxaliplatin; Bisoprolol Fumarate
Possible Avastin side effects in 52 year old female
Reported by a consumer/non-health professional from France on 2012-08-22
Patient: 52 year old female
Reactions: Chest Wall Necrosis
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Dosage: 1 df = 25mg/ml, concentrate for solution for infusion
Start date: 2012-02-01
End date: 2012-06-06
Taxol
Start date: 2012-02-01
End date: 2012-06-06
Possible Avastin side effects in 65 year old female
Reported by a physician from Switzerland on 2012-08-21
Patient: 65 year old female
Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration, Hypokalaemia
Adverse event resulted in: life threatening event, hospitalization, disablity
Drug(s) suspected as cause:
Avastin
Dosage: date of last dose prior to sae: 20/jan/2012
Indication: Adenocarcinoma
Start date: 2011-12-30
Carboplatin
Indication: Adenocarcinoma
Start date: 2011-02-14
Cisplatin
Dosage: date of last dose prior to sae: 20/jan/2012
Indication: Adenocarcinoma
Start date: 2011-12-30
Pemetrexed Disodium
Dosage: date of last dose prior to sae: 20/jan/2012
Indication: Adenocarcinoma
Start date: 2011-12-30
Other drugs received by patient: Crestor; Dolpasse; Potassium Chloride; Norfloxacin
Possible Avastin side effects in female
Reported by a physician from Germany on 2012-08-20
Patient: female, weighing 52.0 kg (114.4 pounds)
Reactions: Syncope, Supraventricular Tachycardia, Dehydration, Pulmonary Oedema
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Dosage: 1 x 90 minutes. last dose prior to sae was taken on 11/jul/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-07-11
Irinotecan Hydrochloride
Dosage: 1 x 2 hours
Indication: Colorectal Cancer Metastatic
Irinotecan Hydrochloride
Start date: 2012-08-01
Xeloda
Dosage: 2 tablets in the morning and 2 tablets in the evening.
Administration route: Oral
Start date: 2012-08-01
Xeloda
Dosage: 3 tablets in the morning and 2 tablets in the evening. last dose prior to sae was taken on 24/jul/20
Indication: Colorectal Cancer Metastatic
Start date: 2012-07-11
Possible Avastin side effects in male
Reported by a physician from Japan on 2012-08-20
Patient: male
Reactions: Pneumonia Aspiration, Haemoptysis
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Avastin
Indication: Lung Adenocarcinoma
Carboplatin
Indication: Lung Adenocarcinoma
Pemetrexed
Indication: Lung Adenocarcinoma
Possible Avastin side effects in male
Reported by a pharmacist from Japan on 2012-08-20
Patient: male, weighing 63.0 kg (138.6 pounds)
Reactions: Back Pain, Dyspnoea, Haemoptysis, Disseminated Intravascular Coagulation, Cold Sweat
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Dosage: 11 course
Indication: Large Intestine Carcinoma
Start date: 2011-12-06
End date: 2012-04-10
Levoleucovorin Calcium
Indication: Large Intestine Carcinoma
Start date: 2011-12-06
End date: 2012-04-10
Oxaliplatin
Dosage: uncertain dosage and 11 course
Indication: Large Intestine Carcinoma
Start date: 2011-12-06
End date: 2012-04-10
Other drugs received by patient: Fluorouracil; Levoleucovorin Calcium; Levoleucovorin Calcium; Granisetron; Dexamethasone Sodium Phosphate; Fluorouracil; Fluorouracil; Fluorouracil
Possible Avastin side effects in 79 year old male
Reported by a consumer/non-health professional from China on 2012-08-20
Patient: 79 year old male
Reactions: Asthma, Productive Cough, Urinary Incontinence, Bronchial Carcinoma, Aphasia, Rash Pruritic, Off Label Use, Poor Quality Sleep, Death, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Emphysema, Stomatitis, Vomiting, Pneumonia, Dyspnoea, Blood Urea Increased, Nausea, Rhinorrhoea, Rash, Diarrhoea, Cerebral Infarction, Depressed Level of Consciousness, Metastases To Bone, Asthenia
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Dosage: unk
Indication: Rectal Cancer Metastatic
Tarceva
Dosage: 150 mg, uid/qd
Administration route: Oral
Indication: Rectal Cancer Metastatic
Start date: 2012-06-01
End date: 2012-06-09
Xeloda
Dosage: 1.5 df, bid for 2 weeks followed by 7 day rest period
Administration route: Oral
Indication: Rectal Cancer Metastatic
End date: 2012-02-23
Possible Avastin side effects in 79 year old male
Reported by a consumer/non-health professional from China on 2012-08-20
Patient: 79 year old male
Reactions: Productive Cough, Aphasia, Bronchial Carcinoma, Rash Pruritic, Poor Quality Sleep, Death, Incontinence, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Emphysema, Dyspnoea, Blood Urea Increased, Stomatitis, Vomiting, Nausea, Rhinorrhoea, Diarrhoea, Cerebral Infarction, Depressed Level of Consciousness, Metastases To Bone, Asthenia
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Indication: Rectal Cancer Metastatic
Tarceva
Administration route: Oral
Indication: Rectal Cancer Metastatic
Start date: 2012-06-01
End date: 2012-06-09
Xeloda
Administration route: Oral
Indication: Rectal Cancer Metastatic
End date: 2012-02-23
Possible Avastin side effects in male
Reported by a physician from Japan on 2012-08-17
Patient: male, weighing 40.0 kg (88.0 pounds)
Reactions: Gastrointestinal Perforation, Wound Dehiscence, Wound Infection, Peritonitis, Disease Progression
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Indication: Colon Cancer Metastatic
Start date: 2012-03-14
End date: 2012-04-25
Fluorouracil
Start date: 2012-02-29
End date: 2012-04-27
Fluorouracil
Dosage: dosage is uncertain.
Indication: Colon Cancer Metastatic
Start date: 2012-02-29
End date: 2012-04-25
Oxaliplatin
Indication: Colon Cancer Metastatic
Start date: 2012-02-29
End date: 2012-04-10
Other drugs received by patient: Loxonin; Emend; Levoleucovorin Calcium; Levoleucovorin Calcium; Emend; Ferrous Citrate; Maglax; Mucosta
Possible Avastin side effects in female
Reported by a physician from Japan on 2012-08-17
Patient: female, weighing 36.0 kg (79.2 pounds)
Reactions: Cardio-Respiratory Arrest, Pneumonia, Haemoptysis, Obstructive Airways Disorder
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Other drugs received by patient: Prochlorperazine; Morphine Sulfate; Alimta; Carboplatin
Possible Avastin side effects in male
Reported by a physician from Austria on 2012-08-17
Patient: male, weighing 99.0 kg (217.8 pounds)
Reactions: Renal Failure, Sepsis, Diarrhoea Haemorrhagic, Leukopenia
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Avastin
Indication: Rectal Neoplasm
Start date: 2012-07-04
Capecitabine
Administration route: Oral
Indication: Rectal Neoplasm
Start date: 2012-07-04
End date: 2012-07-15
Other drugs received by patient: Oxaliplatin
Possible Avastin side effects in female
Reported by a physician from United States on 2012-08-17
Patient: female, weighing 65.3 kg (143.7 pounds)
Reactions: Neutropenic Colitis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Dosage: date of most recent dose prior to sae: 20/mar/2012
Indication: Colon Cancer
Start date: 2012-01-31
Fluorouracil
Fluorouracil
Dosage: date of most recent dose prior to sae: 20/mar/2012
Indication: Colon Cancer
Start date: 2012-01-31
Folinic Acid
Dosage: date of most recent dose prior to sae: 20/mar/2012
Indication: Colon Cancer
Start date: 2012-01-31
Oxaliplatin
Dosage: date of most recent dose prior to sae: 20/mar/2012
Indication: Colon Cancer
Start date: 2012-01-31
Possible Avastin side effects in male
Reported by a physician from Japan on 2012-08-15
Patient: male, weighing 51.0 kg (112.2 pounds)
Reactions: Haemoptysis, Interstitial Lung Disease, Platelet Count Decreased, Hypertension
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Start date: 2010-11-16
End date: 2010-11-16
Avastin
Start date: 2010-12-16
End date: 2010-12-16
Avastin
Start date: 2010-10-14
End date: 2010-10-14
Avastin
Indication: Lung Adenocarcinoma Recurrent
Start date: 2010-08-17
End date: 2010-08-17
Avastin
Start date: 2010-09-14
End date: 2010-09-14
Carboplatin
Start date: 2010-09-14
End date: 2010-09-14
Carboplatin
Start date: 2010-12-16
End date: 2010-12-16
Carboplatin
Start date: 2010-11-16
End date: 2010-11-16
Carboplatin
Indication: Lung Adenocarcinoma Recurrent
Start date: 2010-08-17
End date: 2010-08-17
Carboplatin
Start date: 2010-10-14
End date: 2010-10-14
Paclitaxel
Start date: 2010-09-14
End date: 2010-09-14
Paclitaxel
Indication: Lung Adenocarcinoma Recurrent
Start date: 2010-08-17
End date: 2010-08-17
Paclitaxel
Start date: 2010-10-14
End date: 2010-10-14
Paclitaxel
Start date: 2010-12-16
End date: 2010-12-16
Paclitaxel
Start date: 2010-11-16
End date: 2010-11-16
Possible Avastin side effects in female
Reported by a physician from United States on 2012-08-15
Patient: female, weighing 114.7 kg (252.3 pounds)
Reactions: Cerebrovascular Accident, Acute Respiratory Failure
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Dosage: date of last dose prior to sae 30/jul/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Blinded Onartuzumab
Dosage: date of last dose prior to sae 30/jul/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Fluorouracil
Dosage: date of last dose prior to sae 30/jul/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Leucovorin Calcium
Dosage: 456, date of last dose prior to sae 27/jun/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Oxaliplatin
Dosage: date of last dose prior to sae 13/jun/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Other drugs received by patient: Premarin; Compazine; Losartan Potassium and Hydrochlorothiazide; Tebs EYE Formula FOR Macula Support Smokers Formula; Aspirin; Fibercon; Ativan; Lomotil; Zofran; Magnesium; Crestor; Neupogen
Possible Avastin side effects in male
Reported by a physician from Japan on 2012-08-14
Patient: male, weighing 68.0 kg (149.6 pounds)
Reactions: Intestinal Perforation, Malignant Ascites, Malignant Pleural Effusion, Disseminated Intravascular Coagulation, Septic Shock, Disease Progression, Renal Failure Acute
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Avastin
Dosage: eight times
Start date: 2011-11-14
End date: 2012-04-09
Avastin
Dosage: 26 times
Start date: 2010-08-30
End date: 2011-09-12
Avastin
Dosage: nine times
Indication: Rectal Cancer Recurrent
Start date: 2009-08-17
Avastin
Dosage: eight times
End date: 2010-04-26
Avastin
Dosage: eight times
Start date: 2010-05-10
End date: 2010-08-16
Other drugs received by patient: Oxaliplatin; Fluorouracil; Fluorouracil; Irinotecan HCL; TS-1; Levoleucovorin Calcium; Levoleucovorin Calcium; Fluorouracil; Fluorouracil; Fluorouracil; Levoleucovorin Calcium; Oxaliplatin; Fluorouracil
Possible Avastin side effects in female
Reported by a physician from United States on 2012-08-14
Patient: female, weighing 68.1 kg (149.8 pounds)
Reactions: Lung Neoplasm Malignant, Lower Gastrointestinal Haemorrhage, Cardiac Arrest
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Avastin
Other drugs received by patient: Alimta; Cisplatin
Possible Avastin side effects in female
Reported by a physician from United States on 2012-08-14
Patient: female, weighing 114.7 kg (252.3 pounds)
Reactions: Acute Respiratory Failure, Cerebrovascular Accident
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Dosage: date of last dose prior to sae 30/jul/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Blinded Onartuzumab
Dosage: date of last dose prior to sae 30/jul/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Fluorouracil
Dosage: date of last dose prior to sae 30/jul/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Leucovorin Calcium
Dosage: 456, date of last dose prior to sae 27/jun/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Oxaliplatin
Dosage: date of last dose prior to sae 13/jun/2012
Indication: Colorectal Cancer Metastatic
Start date: 2012-05-30
Other drugs received by patient: Lomotil; Premarin; Compazine; Zofran; Aspirin; Fibercon; Losartan Potassium and Hydrochlorothiazide; Neupogen; Ativan; Crestor; Tebs EYE Formula FOR Macula Support Smokers Formula
Possible Avastin side effects in 50 year old female
Reported by a physician from Japan on 2012-08-13
Patient: 50 year old female, weighing 48.0 kg (105.6 pounds)
Reactions: Renal Impairment, Disease Progression
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Avastin
Indication: Rectal Cancer Metastatic
Start date: 2012-06-01
End date: 2012-06-01
Decadron Phosphate
Indication: Product Used FOR Unknown Indication
Start date: 2012-06-01
End date: 2012-06-01
Decadron Phosphate
Administration route: Oral
Start date: 2012-06-01
End date: 2012-06-03
Oxaliplatin
Indication: Rectal Cancer Metastatic
Start date: 2012-06-01
End date: 2012-06-01
Xeloda
Administration route: Oral
Indication: Rectal Cancer Metastatic
Start date: 2012-06-01
End date: 2012-06-06
Other drugs received by patient: Oxycontin; Aldactone; BIO-Three; Mucosta; Lasix; Prochlorperazine; Magmitt; Loxonin
Possible Avastin side effects in 19 year old female
Reported by a consumer/non-health professional from Ecuador on 2012-08-13
Patient: 19 year old female
Reactions: Vomiting, Dyspnoea, Aphasia, Pyrexia, Asthenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Possible Avastin side effects in male
Reported by a physician from Japan on 2012-08-13
Patient: male, weighing 65.0 kg (143.0 pounds)
Reactions: Intestinal Ischaemia, Disseminated Intravascular Coagulation, Shock
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Indication: Lung Adenocarcinoma Metastatic
Start date: 2012-06-19
End date: 2012-07-18
Carboplatin
Indication: Lung Adenocarcinoma Metastatic
Start date: 2012-06-19
End date: 2012-07-18
Paclitaxel
Indication: Lung Adenocarcinoma Metastatic
Start date: 2012-06-19
End date: 2012-07-18
Other drugs received by patient: Decadron Phosphate; Aloxi
Possible Avastin side effects in 52 year old female
Reported by a physician from France on 2012-08-10
Patient: 52 year old female
Reactions: Chest Wall Necrosis
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Indication: Product Used FOR Unknown Indication
Start date: 2012-02-01
End date: 2012-06-06
Taxol
Indication: Product Used FOR Unknown Indication
Start date: 2012-02-01
End date: 2012-06-06
Possible Avastin side effects in male
Reported by a consumer/non-health professional from Australia on 2012-08-10
Patient: male
Reactions: Grand MAL Convulsion, Brain Oedema
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Possible Avastin side effects in female
Reported by a physician from United States on 2012-08-08
Patient: female, weighing 60.8 kg (133.8 pounds)
Reactions: Back Pain, Swelling Face, Pyrexia, Rash
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Other drugs received by patient: Fluorouracil; Leucovorin Calcium; Fluorouracil; Oxaliplatin
Possible Avastin side effects in female
Reported by a physician from Japan on 2012-08-08
Patient: female
Reactions: Disseminated Intravascular Coagulation, Hepatic Failure, Duodenal Perforation
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Avastin
Other drugs received by patient: Levofloxacin; Paclitaxel; Mucosta; Loxonin; Lyrica; Allopurinol; Kolantyl; Juvela N; Neurovitan (Ukraine)
Possible Avastin side effects in female
Reported by a physician from Japan on 2012-08-08
Patient: female, weighing 50.0 kg (110.0 pounds)
Reactions: Breast Cancer Metastatic, Nausea, Anaemia, Pain, Pulmonary Infarction, Tumour Haemorrhage
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Other drugs received by patient: Mucosta; Paclitaxel; Loxonin; Pursennid
Possible Avastin side effects in male
Reported by a physician from Italy on 2012-08-07
Patient: male
Reactions: Myocardial Infarction
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Dosage: 375 milligram daily;
Indication: Colon Cancer Metastatic
Start date: 2012-01-24
End date: 2012-06-01
Fluorouracil
Dosage: 5376 milligram daily;
Indication: Colon Cancer Metastatic
Start date: 2012-01-24
End date: 2012-06-01
Oxaliplatin
Dosage: 163 milligram daily;
Indication: Colon Cancer Metastatic
Start date: 2012-01-24
End date: 2012-06-01
Possible Avastin side effects in female
Reported by a physician from China on 2012-08-06
Patient: female, weighing 54.0 kg (118.8 pounds)
Reactions: Death, Cardiac Failure
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Avastin
Dosage: most recent dose prior to the event: 21/mar/2012, 840 mg
Indication: non-Small Cell Lung Cancer
Start date: 2012-01-05
Carboplatin
Dosage: most recent dose prior to event: 21/mar/2012, 739 mg
Indication: non-Small Cell Lung Cancer
Start date: 2012-01-05
Paclitaxel
Dosage: most recent dose prior to event: 21/mar/2012, 265 mg
Indication: non-Small Cell Lung Cancer
Start date: 2012-01-05
Possible Avastin side effects in male
Reported by a physician from Japan on 2012-08-06
Patient: male
Reactions: Pneumonia, Vomiting, Oesophagobronchial Fistula, Bacteraemia, Lung Infection, Pneumothorax, Oesophageal Haemorrhage, Delirium
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Avastin
Other drugs received by patient: Alimta; Carboplatin; Aspirin
Possible Avastin side effects in male
Reported by a physician from Japan on 2012-08-03
Patient: male, weighing 75.0 kg (165.0 pounds)
Reactions: Idiopathic Pulmonary Fibrosis
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Alimta
Start date: 2012-02-14
End date: 2012-02-14
Alimta
Dosage: dosage is uncertain.
Indication: Lung Adenocarcinoma Recurrent
Start date: 2012-01-24
End date: 2012-01-24
Avastin
Dosage: dosage is uncertain.
Indication: Lung Adenocarcinoma Recurrent
Start date: 2012-01-24
End date: 2012-02-14
Other drugs received by patient: Hokunalin; Decadron Phosphate; Aloxi; Mucosta; Oxycontin; Mucosolvan; Loxonin; Urso 250
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