Avastin (Bevacizumab) - Hospitalization - Suspected Cause - Side Effect Reports

Possible Avastin side effects in female

Reported by a physician from France on 2012-08-27

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: Skin Mass, Disease Progression

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Cyclophosphamide

Possible Avastin side effects in female

Reported by a physician from United States on 2012-08-27

Patient: female, weighing 84.9 kg (186.8 pounds)

Reactions: Breast Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-06-15
    End date: 2012-08-01

Avastin
    Dosage: last dose prior to event - 27/jul/2012
    Indication: Breast Cancer
    Start date: 2012-06-15

Cyclophosphamide
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-06-15
    End date: 2012-08-01

Possible Avastin side effects in male

Reported by a physician from United States on 2012-08-27

Patient: male, weighing 76.7 kg (168.7 pounds)

Reactions: Pneumonia, Pyrexia, Convulsion

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Glioblastoma Multiforme
    Start date: 2010-04-27
    End date: 2012-05-09

Bortezomib
    Indication: Glioblastoma Multiforme
    Start date: 2010-04-27
    End date: 2010-07-13

Other drugs received by patient: Keppra; Ascorbic Acid; Celexa; Zinc Sulfate; Finasteride; Provigil

Possible Avastin side effects in 62 year old female

Reported by a physician from United States on 2012-08-27

Patient: 62 year old female

Reactions: Mucosal Inflammation, Fatigue, Diarrhoea, Mental Status Changes, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Xeloda
    Indication: Colorectal Cancer Metastatic

Avastin
    Indication: Colorectal Cancer Metastatic

Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-27

Patient: male, weighing 59.0 kg (129.8 pounds)

Reactions: White Blood Cell Count Decreased, Gastrointestinal Haemorrhage, Dyspnoea, Haemoptysis, Cardio-Respiratory Arrest, Depressed Level of Consciousness, Pulmonary Thrombosis, Epistaxis, Oxygen Saturation Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Aspirin
    Dosage: dose form: enteric coating drug
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Warfarin Sodium
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Avastin
    Indication: non-Small Cell Lung Cancer
    Start date: 2010-08-10
    End date: 2010-08-10

Other drugs received by patient: Amaryl; Transamine CAP; Carboplatin; Coniel; Allopurinol; Lasix; Adona; Candesartan Cilexetil; Aldactone; Basen; Gosha-Jinki-GAN; Paclitaxel

Possible Avastin side effects in male

Reported by a physician from Netherlands on 2012-08-27

Patient: male

Reactions: Dyspnoea, Respiratory Failure, Cardiac Arrest

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Colorectal Cancer
    Start date: 2010-12-06

Oxaliplatin
    Indication: Colorectal Cancer
    Start date: 2010-12-06

Xeloda
    Administration route: Oral
    Indication: Colorectal Cancer
    Start date: 2010-12-06

Other drugs received by patient: Glyburide; Rosuvastatin; Augmentin '500'; Telmisartan

Possible Avastin side effects in 72 year old male

Reported by a physician from Israel on 2012-08-24

Patient: 72 year old male

Reactions: Embolism, Dihydropyrimidine Dehydrogenase Deficiency, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin

Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-24

Patient: female, weighing 77.0 kg (169.4 pounds)

Reactions: Dehydration, Bradyarrhythmia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Xeloda
    Indication: Breast Cancer

Vinorelbine Tartrate
    Indication: Breast Cancer

Avastin
    Indication: Breast Cancer

Possible Avastin side effects in male

Reported by a physician from Lebanon on 2012-08-23

Patient: male, weighing 74.5 kg (163.9 pounds)

Reactions: Abscess Neck, Pharyngeal Fistula, Disseminated Intravascular Coagulation, Vascular Pseudoaneurysm, Pharyngeal Ulceration, Septic Shock, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Fluorouracil; Oxaliplatin; Bisoprolol Fumarate

Possible Avastin side effects in male

Reported by a physician from United Kingdom on 2012-08-23

Patient: male

Reactions: Inappropriate Schedule of Drug Administration, Confusional State, Aphasia, Hypoaesthesia, Cerebrovascular Accident, Concomitant Disease Progression, Transient Ischaemic Attack

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lucentis
    Start date: 2011-09-15
    End date: 2011-09-15

Avastin
    Indication: Diabetic Retinal Oedema

Lucentis
    Dosage: last dose prior to ae onset on 13/jul/2011
    Indication: Diabetic Retinal Oedema
    Start date: 2011-02-17

Lucentis
    Start date: 2011-04-21
    End date: 2011-04-21

Lucentis
    Start date: 2011-03-14
    End date: 2011-03-14

Lucentis
    Start date: 2011-05-19
    End date: 2011-05-19

Lucentis
    Start date: 2011-06-13
    End date: 2011-06-13

Other drugs received by patient: Atorvastatin; Novolog MIX 70 / 30; Metformin; Aspirin; Metformin; Isosorbide Mononitrate; Dipyridamole; Irbesartan; Furosemide

Possible Avastin side effects in 63 year old female

Reported by a physician from France on 2012-08-23

Patient: 63 year old female

Reactions: Partial Seizures, Diarrhoea

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Irinotecan Mayne
    Indication: Glioblastoma
    Start date: 2011-04-20
    End date: 2011-05-18

Avastin
    Indication: Glioblastoma
    Start date: 2011-04-20

Other drugs received by patient: Irinotecan Hydrochloride; Methylprednisolone Hemisuccinate; Zofran

Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-22

Patient: male, weighing 72.0 kg (158.4 pounds)

Reactions: Haemorrhage, Perineal Pain, Wound Haemorrhage

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Pydoxal; Irinotecan Hydrochloride; Irinotecan Hydrochloride; TS-1; Irinotecan Hydrochloride; Promac; Tamsulosin HCL

Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-22

Patient: female, weighing 72.0 kg (158.4 pounds)

Reactions: Headache

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Indication: Breast Cancer
    Start date: 2012-04-05

Doxorubicin Hydrochloride
    Indication: Breast Cancer
    Start date: 2012-04-05

Carboplatin
    Indication: Breast Cancer
    Start date: 2012-04-05

Avastin
    Indication: Breast Cancer
    Start date: 2012-04-05

Possible Avastin side effects in male

Reported by a physician from Serbia on 2012-08-22

Patient: male, weighing 62.0 kg (136.4 pounds)

Reactions: Depression

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Roferon-A
    Indication: Renal Cell Carcinoma
    Start date: 2009-12-17
    End date: 2010-11-03

Avastin
    Indication: Renal Cell Carcinoma
    Start date: 2009-12-10
    End date: 2010-10-27

Other drugs received by patient: Enalapril Maleate; Iron

Possible Avastin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-22

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Avastin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Cisplatin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Pemetrexed Disodium
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Other drugs received by patient: Crestor; Potassium Chloride; Norfloxacin; Dolpasse

Possible Avastin side effects in 54 year old female

Reported by a physician from United States on 2012-08-22

Patient: 54 year old female, weighing 47.0 kg (103.4 pounds)

Reactions: Abdominal Pain, Vomiting, Nausea, Anaemia, Hypokalaemia, Small Intestinal Obstruction, Hypomagnesaemia, Platelet Count Decreased, Hypoalbuminaemia, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: last dose prior to sae was taken on 06/jul/2012. day 15 held due to sbo.
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-07-06

Avastin
    Dosage: last dose prior to sae was taken on 29/jun/2012
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-06-29

Carboplatin
    Dosage: auc= 6 over 30 minutes on day 1. last dose prior to sae was taken on 29/may/2012
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-05-29

Veliparib
    Dosage: last dose prior to sae was taken on 03/jul/2012
    Administration route: Oral
    Indication: Ovarian Epithelial Cancer

Possible Avastin side effects in female

Reported by a physician from United States on 2012-08-22

Patient: female, weighing 67.3 kg (148.1 pounds)

Reactions: Drug Dose Omission, Vomiting, Headache, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 7392 mg

Leucovorin Calcium
    Dosage: 1408 mg

Eloxatin
    Dosage: 0 mg

Avastin
    Dosage: 664 mg

Other drugs received by patient: ...

Possible Avastin side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-22

Patient: male, weighing 89.9 kg (197.8 pounds)

Reactions: Vomiting, Dyspnoea, Nausea, Dehydration, Pneumomediastinum, Pneumothorax, Odynophagia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Oxaliplatin
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-15

Avastin
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-15

Xeloda
    End date: 2012-02-26

Avastin
    Dosage: last dose recieved on 14 feb 2012
    End date: 2012-02-14

Herceptin
    Dosage: last dose recieved on 14 feb 2012.
    End date: 2012-02-14

Xeloda
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-29

Herceptin
    Dosage: last dose recieved on 14 feb 2012.
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-10
    End date: 2011-11-15

Oxaliplatin
    End date: 2012-02-14

Other drugs received by patient: Actos; Lorazepam; DTO; Prilosec; Ritalin; Toprol-XL; Potassium Chloride; Lomotil; Dexamethasone; Compazine; Prednisone TAB; Citalopram Hydrobromide; Morphine Sulfate; Lisinopril; Metoprolol Tartrate; Dicyclomine; Methylphenidate; Zofran; Oxycodone HCL; Decadron Phosphate; Bentyl; Emend

Possible Avastin side effects in male

Reported by a physician from Hungary on 2012-08-22

Patient: male, weighing 74.0 kg (162.8 pounds)

Reactions: Pneumonia, Anaemia, Granulocytopenia, Neutropenia, Thrombocytopenia, Leukopenia, Infectious Pleural Effusion

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Gemcitabine Hydrochloride
    Dosage: last dose prior to sae: 01 april 2010

Carboplatin
    Dosage: last dose prior to event on 25 january 2010.

Gemcitabine Hydrochloride

Gemcitabine Hydrochloride
    Dosage: freq: day 1 + 8 every 3 weeks

Carboplatin
    Dosage: form: infusion;
    Indication: non-Small Cell Lung Cancer

Carboplatin
    Dosage: last dose prior to sae: 23 march 2010, frequency: 1xdaily

Avastin
    Dosage: frequency: 1x, form infusion;
    Indication: non-Small Cell Lung Cancer

Gemcitabine Hydrochloride
    Dosage: last dose of iv gemcitabine prior to event on 25 january 2010.

Avastin
    Dosage: frequency as per protocol, last dose of prior to event on 25 january 2010. form infusion

Gemcitabine Hydrochloride
    Dosage: freq: day 1 + 8 every 3 weeks

Avastin
    Dosage: last dose prior to sae: 16 february 2010. last dose prior to leukopenia was 23 mar 2010

Gemcitabine Hydrochloride
    Dosage: form infusion, on day 1 and day 8; frequency: 1xdaily;
    Indication: non-Small Cell Lung Cancer
    Start date: 2009-11-09
    End date: 2009-11-17

Gemcitabine Hydrochloride
    Dosage: frequency: 2xevery three week, form: infusion

Carboplatin

Avastin
    Dosage: last dose prior to sae: 16 february 2010,infusion, frequency: 1xdaily

Other drugs received by patient: Fluticasone Propionate / Salmeterol; Augmentin '500'; Kalium-R; Sinecod; Ondansetron; Bisoprolol Fumarate; Pegfilgrastim; Lidocaine; Ciprofloxacin Hydrochloride; Neupogen; Spiriva; Kalium-R; Eprex; Neorecormon; Hydromorphone HCL; Berodual; Fluticasone Propionate / Salmeterol; Neorecormon; Augmentin '500'; Kalium-R; Medrol; Medrol; Neupogen; Medrol; Bisoprolol Fumarate; Spiriva; Megesin; Megesin

Possible Avastin side effects in 78 year old male

Reported by a physician from Japan on 2012-08-21

Patient: 78 year old male

Reactions: Blood Bilirubin Increased, Renal Disorder, Pneumonia, Cancer Pain, Pulmonary Fibrosis, Liver Disorder, Haemoglobin Decreased, Respiratory Failure, Interstitial Lung Disease, Platelet Count Decreased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2012-03-05
    End date: 2012-05-07

Avastin
    Dosage: dosage is uncertain.
    Start date: 2012-06-11
    End date: 2012-07-09

Other drugs received by patient: Pemetrexed Disodium; Pemetrexed Disodium; Carboplatin

Possible Avastin side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-21

Patient: 65 year old female

Reactions: Urticaria, Hepatocellular Injury, Cholestasis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: unk
    Indication: Breast Cancer
    Start date: 2012-02-01
    End date: 2012-07-16

Midodrine Hydrochloride
    Dosage: unk
    Administration route: Oral
    Indication: Orthostatic Hypotension
    Start date: 2012-06-22
    End date: 2012-07-16

Chlorpromazine HCL
    Dosage: 200 drop(s)
    Administration route: Oral
    Indication: Major Depression
    Start date: 2012-06-20
    End date: 2012-06-28

Zofran
    Dosage: 8 mg, weekly
    Administration route: Oral
    Indication: Vomiting
    Start date: 2012-02-01
    End date: 2012-07-16

Zyprexa
    Dosage: 10 mg, 1x/day
    Administration route: Oral
    Indication: Major Depression
    Start date: 2012-06-28
    End date: 2012-07-16

Paclitaxel
    Dosage: unk
    Indication: Breast Cancer Recurrent
    Start date: 2012-02-01
    End date: 2012-07-16

Anafranil
    Dosage: 150 mg, 1x/day
    Administration route: Oral
    Indication: Major Depression
    Start date: 2012-06-22

Other drugs received by patient: Nexium

Possible Avastin side effects in 74 year old male

Reported by a physician from United States on 2012-08-21

Patient: 74 year old male, weighing 102.1 kg (224.6 pounds)

Reactions: Chronic Obstructive Pulmonary Disease

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: lasat dose prior to sae: 02/aug/2012
    Indication: Bronchioloalveolar Carcinoma
    Start date: 2012-05-30

Carboplatin
    Indication: Bronchioloalveolar Carcinoma
    Start date: 2012-05-30

Avastin
    Indication: Bronchioloalveolar Carcinoma
    Start date: 2012-05-30

Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-21

Patient: female, weighing 72.0 kg (158.4 pounds)

Reactions: Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Breast Cancer
    Start date: 2012-03-13
    End date: 2012-05-22

Doxorubicin HCL
    Indication: Breast Cancer
    Start date: 2012-03-13
    End date: 2012-05-22

Paclitaxel
    Indication: Breast Cancer
    Start date: 2012-03-13
    End date: 2012-05-22

Other drugs received by patient: Filgrastim; Ranitidine; Granisetron; Dexamethasone; Clemastine Fumarate

Possible Avastin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-21

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration, Hypokalaemia

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Pemetrexed Disodium
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Cisplatin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Avastin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Other drugs received by patient: Crestor; Dolpasse; Potassium Chloride; Norfloxacin

Possible Avastin side effects in male

Reported by a physician from Italy on 2012-08-20

Patient: male

Reactions: Paralysis, Cerebral Ischaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Folina; Scopolamine; Ranitidine HCL; Fluorouracil; Zofran; Betamethasone Sodium Phosphate; Oxaliplatin

Possible Avastin side effects in male

Reported by a physician from Denmark on 2012-08-20

Patient: male

Reactions: Fistula

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Irinotecan HCL
    Dosage: 180 mg/m2, cyclic, 14 days
    Indication: Colorectal Cancer
    Start date: 2012-02-23
    End date: 2012-04-12

Fluorouracil
    Dosage: cyclic, 14 days
    Indication: Colorectal Cancer
    Start date: 2012-02-23
    End date: 2012-04-12

Avastin
    Dosage: 5 mg/kg, unk
    Indication: Colorectal Cancer
    Start date: 2012-03-15
    End date: 2012-04-12

Other drugs received by patient: Enalapril Maleate; Prednisolone; Vitamin D; Ondansetron; Atropine

Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-20

Patient: female, weighing 77.0 kg (169.4 pounds)

Reactions: Dehydration, Bradyarrhythmia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Xeloda
    Indication: Breast Cancer

Avastin
    Indication: Breast Cancer

Vinorelbine Tartrate
    Indication: Breast Cancer

Possible Avastin side effects in 59 year old male

Reported by a physician from United States on 2012-08-20

Patient: 59 year old male, weighing 92.1 kg (202.6 pounds)

Reactions: Oesophageal Fistula, Post Procedural Haemorrhage

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Docetaxel
    Dosage: over 1 hour on day 1, last dose prior to the event: 12/jul/2012
    Indication: Head and Neck Cancer
    Start date: 2012-05-23

Carboplatin
    Dosage: auc 6 over 30 minutes on day 1, last dose prior to the event: 12/jul/2012
    Indication: Head and Neck Cancer
    Start date: 2012-05-23

Avastin
    Dosage: on day 1 over 30-90 minutes, last dose prior to the event: 23/may/2012
    Indication: Head and Neck Cancer
    Start date: 2012-05-23

Possible Avastin side effects in 48 year old male

Reported by a physician from Japan on 2012-08-20

Patient: 48 year old male

Reactions: Bronchopulmonary Aspergillosis, Septic Shock

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: non-Small Cell Lung Cancer Metastatic
    Start date: 2011-07-05
    End date: 2012-01-01

Avastin
    Start date: 2012-06-01

Other drugs received by patient: TS-1; TS-1; Aspirin

Possible Avastin side effects in 70 year old female

Reported by a physician from United States on 2012-08-20

Patient: 70 year old female, weighing 55.5 kg (122.1 pounds)

Reactions: Small Intestinal Obstruction, Urinary Tract Obstruction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Start date: 2012-03-12

Dasatinib
    Dosage: 100 mg po qd cycle 1,2 cycle=28 days,sob occured during c3 on 30/mar/2012.dasatinib was held between
    Administration route: Oral
    Indication: Neoplasm
    Start date: 2012-01-09

Avastin
    Dosage: 10 mg/kg over 30-90 min q 2 wks, cycle=28 days (cycle2+) last dose administered on 04/jun/2012,c3 wa
    Indication: Neoplasm
    Start date: 2012-01-09
    End date: 2012-03-05

Other drugs received by patient: Metoprolol Tartrate; Glipizide; Januvia; Magnesium; Triplex AD (United States); Levothyroxine Sodium