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Avastin (Bevacizumab) - Decreased Appetite - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Decreased Appetite (132)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Avastin (Bevacizumab) where reactions include decreased appetite. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 132   Next >>

Possible Avastin side effects in 62 year old female

Reported by a physician from United States on 2012-08-27

Patient: 62 year old female

Reactions: Mucosal Inflammation, Fatigue, Diarrhoea, Mental Status Changes, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Colorectal Cancer Metastatic

Xeloda
    Indication: Colorectal Cancer Metastatic



Possible Avastin side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-22

Patient: male, weighing 89.9 kg (197.8 pounds)

Reactions: Vomiting, Dyspnoea, Nausea, Dehydration, Pneumomediastinum, Pneumothorax, Odynophagia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-15

Avastin
    Dosage: last dose recieved on 14 feb 2012
    End date: 2012-02-14

Herceptin
    Dosage: last dose recieved on 14 feb 2012.
    End date: 2012-02-14

Herceptin
    Dosage: last dose recieved on 14 feb 2012.
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-10
    End date: 2011-11-15

Oxaliplatin
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-15

Oxaliplatin
    End date: 2012-02-14

Xeloda
    End date: 2012-02-26

Xeloda
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-29

Other drugs received by patient: Actos; Lorazepam; DTO; Prilosec; Ritalin; Toprol-XL; Potassium Chloride; Lomotil; Dexamethasone; Compazine; Prednisone TAB; Citalopram Hydrobromide; Morphine Sulfate; Lisinopril; Metoprolol Tartrate; Dicyclomine; Methylphenidate; Zofran; Oxycodone HCL; Decadron Phosphate; Bentyl; Emend



Possible Avastin side effects in 79 year old male

Reported by a consumer/non-health professional from China on 2012-08-20

Patient: 79 year old male

Reactions: Productive Cough, Aphasia, Bronchial Carcinoma, Rash Pruritic, Poor Quality Sleep, Death, Incontinence, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Emphysema, Dyspnoea, Blood Urea Increased, Stomatitis, Vomiting, Nausea, Rhinorrhoea, Diarrhoea, Cerebral Infarction, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Rectal Cancer Metastatic

Tarceva
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in 79 year old male

Reported by a consumer/non-health professional from China on 2012-08-20

Patient: 79 year old male

Reactions: Asthma, Productive Cough, Urinary Incontinence, Bronchial Carcinoma, Aphasia, Rash Pruritic, Off Label Use, Poor Quality Sleep, Death, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Emphysema, Stomatitis, Vomiting, Pneumonia, Dyspnoea, Blood Urea Increased, Nausea, Rhinorrhoea, Rash, Diarrhoea, Cerebral Infarction, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: unk
    Indication: Rectal Cancer Metastatic

Tarceva
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Dosage: 1.5 df, bid for 2 weeks followed by 7 day rest period
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-16

Patient: male, weighing 51.8 kg (113.9 pounds)

Reactions: Peripheral Coldness, Nausea, Skin Exfoliation, Pain in Extremity, Hypoaesthesia, DRY Skin, Erythema, Dysgeusia, Protein Urine, Fatigue, Diarrhoea, Skin Discolouration, Feeling Hot, Decreased Appetite

Drug(s) suspected as cause:
Avastin
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-03-01

Xeloda
    Dosage: 2000mg in morning, 1500 mg in night
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-03-01
    End date: 2012-07-01



Possible Avastin side effects in female

Reported by a physician from Japan on 2012-08-14

Patient: female, weighing 37.0 kg (81.4 pounds)

Reactions: Pulmonary Haemorrhage, Pneumonia, Spinal Compression Fracture, Haemoptysis, Enterocolitis, Acute Respiratory Failure, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Colon Cancer Recurrent
    Start date: 2010-09-27
    End date: 2012-06-22

Avastin
    Start date: 2011-05-27
    End date: 2012-06-22

Irinotecan Hydrochloride
    Dosage: dosage is uncertain.
    Indication: Colon Cancer Recurrent
    Start date: 2011-05-27
    End date: 2012-06-22

TS-1
    Dosage: dosage is uncertain.
    Administration route: Oral
    Start date: 2011-05-27
    End date: 2012-06-22

TS-1
    Dosage: dosage is uncertain.
    Administration route: Oral
    Start date: 2010-09-27
    End date: 2011-05-06

TS-1
    Dosage: dosage is uncertain.
    Administration route: Oral
    Indication: Colon Cancer Recurrent
    Start date: 2010-07-07
    End date: 2010-09-01

Other drugs received by patient: Oxaliplatin; Decadron Phosphate; Protecadin; Promac



Possible Avastin side effects in

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-13

Patient:

Reactions: Abdominal Pain, Blood Bilirubin Increased, Thrombosis, Anal Examination Abnormal, Hypokalaemia, Fatigue, Proteinuria, Abdominal Distension, Decreased Appetite, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Hyponatraemia, Small Intestinal Obstruction, Hypophosphataemia, Diarrhoea, Alopecia, Dehydration, Neutropenia, Hypertension, Vascular Access Complication

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Dosage: given on day 1
    Indication: Colorectal Cancer Metastatic

Irinotecan Hydrochloride and Irinotecan Hydrochloride
    Dosage: given on day 1
    Indication: Colorectal Cancer Metastatic

Xeloda
    Dosage: 1000 mg/m2 twice daily for age below 65 years,750 mg/m2 twice daily for age above 65 years
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic



Possible Avastin side effects in female

Reported by a physician from France on 2012-08-09

Patient: female

Reactions: Death, Diarrhoea, Alopecia, Asthenia, Epistaxis, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Start date: 2009-05-05
    End date: 2010-06-08

Avastin
    Start date: 2010-06-29
    End date: 2010-06-29

Avastin
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-08-31
    End date: 2008-09-10

Capecitabine
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-01-23
    End date: 2012-03-18

Fluorouracil
    Indication: Product Used FOR Unknown Indication
    Start date: 2002-06-17
    End date: 2003-12-23

Fluorouracil
    Start date: 2009-05-05
    End date: 2010-06-08

Fluorouracil
    Start date: 2011-09-28
    End date: 2011-09-28

Fluorouracil
    Start date: 2011-08-11
    End date: 2011-09-14

Fluorouracil
    Start date: 2005-08-31
    End date: 2008-09-10

Irinotecan HCL
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-11
    End date: 2011-09-14

Leucovorin Calcium
    Start date: 2011-08-11
    End date: 2011-09-14

Leucovorin Calcium
    Start date: 2009-05-05
    End date: 2010-06-08

Leucovorin Calcium
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-08-31
    End date: 2008-09-10

Leucovorin Calcium
    Start date: 2011-09-28
    End date: 2011-09-28

Leucovorin Calcium
    Indication: Product Used FOR Unknown Indication
    Start date: 2002-06-17
    End date: 2003-12-23

Oxaliplatin
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-08-31
    End date: 2008-09-10

Oxaliplatin
    Start date: 2009-05-05
    End date: 2010-06-08



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-09

Patient: male

Reactions: Fracture, Asthenia, Decreased Appetite

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Fluorouracil; Fluorouracil; Irinotecan HCL; Leucovorin Calcium; Irinotecan HCL; Leucovorin Calcium



Possible Avastin side effects in female

Reported by a physician from France on 2012-08-09

Patient: female

Reactions: Mucosal Inflammation, Death, Nausea, Anaemia, Toxicity To Various Agents, Asthenia, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Indication: Colon Cancer

Avastin
    Start date: 2010-10-27
    End date: 2011-01-27

Xeloda
    Indication: Colon Cancer
    Start date: 2011-04-15
    End date: 2011-08-19

Other drugs received by patient: Leucovorin Calcium; Fluorouracil; Vectibix; Leucovorin Calcium; Fluorouracil; Irinotecan HCL; Oxaliplatin; Oxaliplatin



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-09

Patient: male

Reactions: Vomiting, Nausea, Disease Progression, Gastritis, Neuropathy Peripheral, Diarrhoea, Neutropenia, Thrombocytopenia, Asthenia, Decreased Appetite

Drug(s) suspected as cause:
Avastin
    Dosage: 12 courses of bevacizumab, first line treatment
    Indication: Colon Cancer
    Start date: 2008-06-30
    End date: 2008-12-23

Avastin
    Dosage: 6 courses of bevacizumab
    Start date: 2009-02-02
    End date: 2009-05-18

Other drugs received by patient: Fluorouracil; Leucovorin Calcium; Oxaliplatin



Possible Avastin side effects in 61 year old female

Reported by a physician from United States on 2012-08-08

Patient: 61 year old female, weighing 49.3 kg (108.5 pounds)

Reactions: Vomiting, Oesophagitis, Nausea, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: date of last dsoe received 17/jul/2012
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-06-05

Blinded Everolimus
    Dosage: date of last dose received 17/jul/2012
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-06-05



Possible Avastin side effects in female

Reported by a physician from France on 2012-08-08

Patient: female

Reactions: Diarrhoea, Nausea, Asthenia, Decreased Appetite, Disease Progression

Drug(s) suspected as cause:
Avastin
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-06-18
    End date: 2009-12-28

Avastin
    Start date: 2010-01-18
    End date: 2010-05-03

Other drugs received by patient: Irinotecan HCL; Capecitabine; Oxaliplatin; Irinotecan HCL



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-08

Patient: female, weighing 57.0 kg (125.4 pounds)

Reactions: Fatigue, Dyspnoea, General Physical Health Deterioration, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: last dose prior to sae 13/jun/2012
    Indication: Breast Cancer
    Start date: 2012-04-30

Vinorelbine Tartrate
    Dosage: last dose prior to sae 18 jun 2012
    Indication: Breast Cancer
    Start date: 2012-04-30
    End date: 2012-05-21

Xeloda
    Dosage: last dose prior to sae 22 jun 2012
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-04-30
    End date: 2012-06-03

Other drugs received by patient: Furosemide; Amlodipine; Amitriptyline HCL; Novalgin



Possible Avastin side effects in 78 year old male

Reported by a consumer/non-health professional from China on 2012-08-07

Patient: 78 year old male

Reactions: Productive Cough, Asthma, Aphasia, Bronchial Carcinoma, Rash Pruritic, Death, Off Label Use, Incontinence, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Stomatitis, Dyspnoea, Vomiting, Blood Urea Increased, Nausea, Diarrhoea, Insomnia, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: unk
    Indication: Rectal Cancer Metastatic

Tarceva
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Dosage: 1.5 df, bid for 2 weeks followed by 7 day rest period
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in female

Reported by a consumer/non-health professional from Belgium on 2012-08-06

Patient: female, weighing 62.4 kg (137.3 pounds)

Reactions: Large Intestine Perforation, Fatigue, Oedema, Pulmonary Embolism, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Colon Cancer
    Start date: 2012-05-22
    End date: 2012-07-04

Fluorouracil
    Indication: Colon Cancer
    Start date: 2012-05-22

Fluorouracil
    Start date: 2012-05-22

Irinotecan Hydrochloride
    Indication: Colon Cancer
    Start date: 2012-05-22

Leucovorin Calcium
    Indication: Colon Cancer
    Start date: 2012-05-22

Other drugs received by patient: Aldactone; Innohep; Meropenem; Pantoprazole; Sandostatin; Promagnor; Tramadol HCL; Acetaminophen; Aranesp; Medrol; Morphine



Possible Avastin side effects in 78 year old male

Reported by a consumer/non-health professional from China on 2012-08-06

Patient: 78 year old male

Reactions: Productive Cough, Asthma, Aphasia, Bronchial Carcinoma, Rash Pruritic, Death, Incontinence, Oedema Peripheral, Blood Creatinine Increased, Decreased Appetite, Epistaxis, Vomiting, Stomatitis, Dyspnoea, Blood Urea Increased, Nausea, Diarrhoea, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Rectal Cancer Metastatic

Tarceva
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in

Reported by a consumer/non-health professional from China on 2012-08-03

Patient:

Reactions: Fatigue, Decreased Appetite, Disease Progression

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in male

Reported by a consumer/non-health professional from China on 2012-08-03

Patient: male

Reactions: Fatigue, Decreased Appetite, Disease Progression

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in female

Reported by a consumer/non-health professional from Belgium on 2012-07-31

Patient: female, weighing 62.4 kg (137.3 pounds)

Reactions: Large Intestine Perforation, Fatigue, Oedema, Pulmonary Embolism, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Colon Cancer
    Start date: 2012-05-22
    End date: 2012-07-04

Fluorouracil
    Start date: 2012-05-22

Fluorouracil
    Indication: Colon Cancer
    Start date: 2012-05-22

Irinotecan HCL
    Indication: Colon Cancer
    Start date: 2012-05-22

Leucovorin Calcium
    Indication: Colon Cancer
    Start date: 2012-05-22

Other drugs received by patient: Promagnor; Medrol; Pantoprazole; Innohep; Aldactone; Tramadol HCL; Morphine Sulfate; Acetaminophen; Meropenem; Sandostatin



Possible Avastin side effects in 70 year old male

Reported by a consumer/non-health professional from United States on 2012-07-27

Patient: 70 year old male, weighing 89.0 kg (195.8 pounds)

Reactions: Weight Decreased, Chapped Lips, Lacrimal Disorder, Fatigue, Malaise, Ageusia, Oral Pain, Decreased Appetite, Aphonia, Epistaxis

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Oxaliplatin; Fluorouracil



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-07-27

Patient: male, weighing 48.0 kg (105.6 pounds)

Reactions: White Blood Cell Count Decreased, Pneumonia Aspiration, Vomiting, Pulmonary Embolism, Leukoencephalopathy, Pyrexia, Neutrophil Count Decreased, Decreased Appetite

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Alimta
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2012-03-13
    End date: 2012-03-13

Avastin
    Indication: Lung Neoplasm Malignant
    Start date: 2012-03-13
    End date: 2012-03-13

Carboplatin
    Dosage: dosage: 5 auc a day
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2012-03-13
    End date: 2012-03-13

Methylprednisolone Sodium Succinate
    Dosage: dosage is uncertain.
    Indication: Leukoencephalopathy
    Start date: 2012-04-26
    End date: 2012-01-01

Other drugs received by patient: Tannalbin; Panvitan; Flivas; Neuer; Medicon; Urso 250; Eviprostat



Possible Avastin side effects in female

Reported by a physician from Japan on 2012-07-25

Patient: female, weighing 37.0 kg (81.4 pounds)

Reactions: Pulmonary Haemorrhage, Pneumonia, Spinal Compression Fracture, Haemoptysis, Acute Respiratory Failure, Enterocolitis, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Indication: Colon Cancer Metastatic
    Start date: 2010-09-27
    End date: 2012-06-22

Avastin
    Indication: Colon Cancer Recurrent
    Start date: 2011-05-27
    End date: 2012-06-22

Irinotecan Hydrochloride
    Dosage: dosage is uncertain.
    Indication: Colon Cancer Metastatic
    Start date: 2011-05-27
    End date: 2012-06-22

TS-1
    Dosage: dosage is uncertain.
    Administration route: Oral
    Indication: Colon Cancer Metastatic
    Start date: 2010-07-07
    End date: 2010-09-01

TS-1
    Dosage: dosage is uncertain.
    Administration route: Oral
    Indication: Colon Cancer Recurrent
    Start date: 2010-09-27
    End date: 2011-05-06

TS-1
    Dosage: dosage is uncertain.
    Administration route: Oral
    Start date: 2011-05-27
    End date: 2012-06-22

Other drugs received by patient: Oxaliplatin; Decadron; Promacta; Protecadin



Possible Avastin side effects in 65 year old female

Reported by a physician from Germany on 2012-07-23

Patient: 65 year old female, weighing 46.4 kg (102.1 pounds)

Reactions: Weight Decreased, Fistula, Nausea, Anaemia, General Physical Health Deterioration, Fatigue, Sepsis, Decreased Appetite, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Ovarian Cancer
    Start date: 2012-03-21
    End date: 2012-04-18

Avastin
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Carboplatin
    Dosage: auc 5,
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Carboplatin
    Dosage: auc 5, last dose:15/may/2012
    End date: 2012-06-10

Paclitaxel
    Dosage: last dose:15/may/2012
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Paclitaxel
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Other drugs received by patient: Novalgin; Pantoprazole; Zolpidem



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-07-19

Patient: female

Reactions: Weight Decreased, Pulmonary Embolism, Pyrexia, Hyperhidrosis, Cardiac Disorder, Intestinal Perforation, Dyspepsia, Proteinuria, Epistaxis, Gingival Bleeding, Anaemia, Cardiomyopathy, Neutropenia, Hypersensitivity, Bone Pain, Pain, Chills, Skin Reaction, Abdominal Pain Upper, Polyneuropathy, Myalgia, Fatigue, Oedema, Dizziness, Myocardial Infarction, Nail Toxicity, Thrombocytopenia, Decreased Appetite, Vomiting, Dyspnoea, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Cerebrovascular Accident, Dysgeusia, Mucosal Inflammation, Anxiety, Diarrhoea, Impaired Healing, Arthralgia, Hypertension, Asthenia, Leukopenia

Drug(s) suspected as cause:
Avastin
    Indication: Breast Cancer

Herceptin
    Indication: Breast Cancer

Xeloda
    Indication: Breast Cancer



Possible Avastin side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-18

Patient: male, weighing 52.2 kg (114.9 pounds)

Reactions: Skin Exfoliation, Pain in Extremity, Nausea, DRY Skin, Erythema, Protein Urine, Dysgeusia, Fatigue, Diarrhoea, Skin Discolouration, Feeling Hot, Decreased Appetite

Drug(s) suspected as cause:
Avastin
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-03-01

Xeloda
    Dosage: 2000mg in morning, 1500 mg in night
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-03-01
    End date: 2012-07-01



Possible Avastin side effects in 70 year old male

Reported by a physician from Japan on 2012-07-18

Patient: 70 year old male

Reactions: Colon Cancer Recurrent, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Dosage: dosage is uncertain.

Avastin
    Dosage: dosage is uncertain.
    Indication: Colon Cancer Recurrent

Other drugs received by patient: Oxaliplatin; Irinotecan HCL; Fluorouracil; Fluorouracil; Levoleucovorin Calcium; Levoleucovorin Calcium; Fluorouracil; Fluorouracil



Possible Avastin side effects in male

Reported by a physician from Germany on 2012-07-13

Patient: male

Reactions: Enterobacter Infection, Weight Decreased, General Physical Condition Abnormal, Vomiting, Wound Dehiscence, Bronchopneumonia, Post Procedural Complication, Fungaemia, Intestinal Perforation, C-Reactive Protein Increased, Staphylococcal Infection, Cardiopulmonary Failure, Depressed Mood, Rectal Abscess, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Rectal Cancer
    Start date: 2011-07-08
    End date: 2011-09-15

Camptosar
    Indication: Rectal Cancer
    Start date: 2011-07-08
    End date: 2011-09-15

Fluorouracil
    Indication: Rectal Cancer
    Start date: 2011-07-08
    End date: 2011-09-15

Leucovorin Calcium
    Indication: Rectal Cancer
    Start date: 2011-07-08
    End date: 2011-09-15



Possible Avastin side effects in female

Reported by a physician from United States on 2012-07-11

Patient: female, weighing 31.8 kg (70.0 pounds)

Reactions: Weight Decreased, Abdominal Discomfort, Epistaxis, Product Counterfeit, Back Pain, Stomatitis, Wound Dehiscence, Pain in Extremity, Drug Intolerance, Toxicity To Various Agents, Paraesthesia, Eating Disorder, Tremor, Metastases To Spine, Skin Exfoliation, Abdominal Pain Upper, Death, Nephrolithiasis, Fatigue, Neuropathy Peripheral, Abdominal Distension, Decreased Appetite, Pain in JAW, White Blood Cell Count Decreased, Vomiting, Drug Hypersensitivity, Incorrect Dose Administered, Deformity, Skin Irritation, Ascites, Limb Deformity, Lung Disorder, Neoplasm Malignant, Flank Pain

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin

Avastin
    Start date: 2008-12-18
    End date: 2009-01-07

Avastin
    Indication: Colorectal Cancer Metastatic

Avastin
    Start date: 2007-08-01
    End date: 2007-09-01

Avastin
    Start date: 2009-01-28
    End date: 2009-05-13

Avastin

Avastin

Avastin
    Start date: 2009-05-27
    End date: 2009-09-01

Fluorouracil
    Dosage: bolus
    Start date: 2009-05-27
    End date: 2009-09-01

Fluorouracil
    Dosage: 7 cycles
    Indication: Colorectal Cancer Metastatic
    Start date: 2009-01-28
    End date: 2009-05-13

Fluorouracil

Folinic Acid
    Start date: 2009-05-27
    End date: 2009-09-01

Folinic Acid
    Dosage: 7 cycles
    Indication: Colorectal Cancer Metastatic
    Start date: 2009-01-28
    End date: 2009-05-13

Folinic Acid

Irinotecan Hydrochloride
    Indication: Colorectal Cancer Metastatic
    Start date: 2010-01-01

Oxaliplatin
    Start date: 2008-06-01
    End date: 2008-06-01

Oxaliplatin
    Dosage: 7 cycles

Oxaliplatin

Oxaliplatin

Oxaliplatin
    Start date: 2009-05-13
    End date: 2009-05-13

Oxaliplatin
    Indication: Colorectal Cancer Metastatic

Oxaliplatin
    Start date: 2008-12-18
    End date: 2008-12-18

Oxaliplatin

Oxaliplatin
    Dosage: dose lowered

Oxaliplatin

Xeloda
    Administration route: Oral

Xeloda
    Dosage: two cycles
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic
    Start date: 2008-12-18
    End date: 2009-01-07

Xeloda
    Administration route: Oral

Xeloda
    Dosage: two tablets in morning
    Administration route: Oral

Other drugs received by patient: Dexamethasone; Zofran; Prilosec



Possible Avastin side effects in male

Reported by a physician from Hungary on 2012-07-09

Patient: male, weighing 57.0 kg (125.4 pounds)

Reactions: Haemoglobin Decreased, Cardiopulmonary Failure, Asthenia, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: frequency reported as bi weekly
    Indication: Renal Cell Carcinoma
    Start date: 2008-09-25
    End date: 2008-10-08

Roferon-A
    Dosage: reported as roferon.dose: 3 mu. frequency weekly 3
    Indication: Renal Cell Carcinoma
    Start date: 2008-09-25
    End date: 2008-10-08

Other drugs received by patient: Ensure



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