This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Avastin (Bevacizumab) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (4689)
Death (1648)
Life Threatening Events (302)
Disability (145)
Reports by Reaction Type
Death (741),
Disease Progression (373),
Diarrhoea (250),
Nausea (230),
Hypertension (209),
Vomiting (207),
Fatigue (156),
General Physical Health Deterioration (149),
Anaemia (139),
Decreased Appetite (132),
Abdominal Pain (131),
Dyspnoea (130)
Below are a few examples of reports where side effects / adverse reactions may be related to Avastin (Bevacizumab). For a complete list or a specific selection of reports, please use the links above.
Possible Avastin side effects in
Reported by a individual with unspecified qualification from United States on 2012-08-27
Patient:
Reactions: Electrocardiogram QT Prolonged, Proctitis, Rhabdomyolysis, Gastrointestinal Haemorrhage, Hyperbilirubinaemia, Hypokalaemia, Neuropathy Peripheral, Intestinal Perforation, Fatigue, Proteinuria, Thrombocytopenia, Azotaemia, Hypovolaemia, Blood Alkaline Phosphatase Increased, Fistula, Stomatitis, Hyperglycaemia, Hyponatraemia, Hyperlipidaemia, Hypophosphataemia, Diarrhoea, Hypoalbuminaemia, Neutropenia, Abscess, Vaginal Infection, Hypertension
Drug(s) suspected as cause:
Avastin
Indication: Colorectal Cancer Metastatic
Everolimus
Administration route: Oral
Indication: Colorectal Cancer Metastatic
Possible Avastin side effects in female
Reported by a physician from United States on 2012-08-27
Patient: female
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Tarceva
Indication: Lung Neoplasm Malignant
Avastin
Indication: Product Used FOR Unknown Indication
Possible Avastin side effects in 73 year old
Reported by a physician from Canada on 2012-08-27
Patient: 73 year old
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Indication: Lung Neoplasm Malignant
Tarceva
Indication: Lung Neoplasm Malignant
Possible Avastin side effects in
Reported by a physician from Spain on 2012-08-27
Patient:
Reactions: Drug Intolerance
Drug(s) suspected as cause:
Avastin
Possible Avastin side effects in female
Reported by a physician from France on 2012-08-27
Patient: female, weighing 54.0 kg (118.8 pounds)
Reactions: Skin Mass, Disease Progression
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Avastin
Other drugs received by patient: Cyclophosphamide
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Disease Progression
Drug(s) suspected as cause:
Avastin
Indication: Haematological Malignancy
Avastin
Indication: Malignant Respiratory Tract Neoplasm
Tarceva
Indication: Product Used FOR Unknown Indication
Possible Avastin side effects in female
Reported by a physician from Canada on 2012-08-27
Patient: female, weighing 86.0 kg (189.2 pounds)
Reactions: Angina Unstable, Proteinuria
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Lucentis
Indication: Product Used FOR Unknown Indication
Avastin
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Metoprolol Tartrate; Risedronate Sodium; Diovan; Lansoprazole; Novolin 70 / 30; Plavix; Lipitor; Amlodipine; Gabapentin; Calcium Carbonate
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Disease Progression
Drug(s) suspected as cause:
Avastin
Indication: Lung Neoplasm Malignant
Start date: 2005-11-01
Tarceva
Indication: Product Used FOR Unknown Indication
Start date: 2005-06-01
Other drugs received by patient: Carboplatin; Taxotere; Taxol
Possible Avastin side effects in 73 year old male
Reported by a physician from France on 2012-08-27
Patient: 73 year old male, weighing 71.0 kg (156.2 pounds)
Reactions: Folliculitis, Rash
Drug(s) suspected as cause:
Fluorouracil
Indication: Colorectal Cancer
Start date: 2012-05-22
End date: 2012-06-27
Avastin
Indication: Colorectal Cancer
Start date: 2012-05-22
End date: 2012-06-06
Other drugs received by patient: Leucovorin Calcium
Possible Avastin side effects in 41 year old male
Reported by a physician from Austria on 2012-08-27
Patient: 41 year old male
Reactions: Neoplasm Progression, General Physical Health Deterioration
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Indication: Brain Neoplasm Malignant
Irinotecan Hydrochloride
Indication: Brain Neoplasm Malignant
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Rash, Deep Vein Thrombosis, Disease Progression
Drug(s) suspected as cause:
Avastin
Indication: Renal Cancer
Start date: 2004-08-01
Tarceva
Indication: Renal Cancer
Start date: 2004-12-26
Other drugs received by patient: Aredia; Thalidomide; Proleukin; Zometa
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Disease Progression
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Indication: Pancreatic Carcinoma
Xeloda
Indication: Pancreatic Carcinoma
Tarceva
Indication: Pancreatic Carcinoma
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Disease Progression
Drug(s) suspected as cause:
Tarceva
Indication: Renal Cancer
Avastin
Indication: Renal Cancer
Possible Avastin side effects in male
Reported by a physician from Netherlands on 2012-08-27
Patient: male
Reactions: Dyspnoea, Respiratory Failure, Cardiac Arrest
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Avastin
Indication: Colorectal Cancer
Start date: 2010-12-06
Oxaliplatin
Indication: Colorectal Cancer
Start date: 2010-12-06
Xeloda
Administration route: Oral
Indication: Colorectal Cancer
Start date: 2010-12-06
Other drugs received by patient: Glyburide; Rosuvastatin; Augmentin '500'; Telmisartan
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male, weighing 76.7 kg (168.7 pounds)
Reactions: Pneumonia, Pyrexia, Convulsion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Avastin
Indication: Glioblastoma Multiforme
Start date: 2010-04-27
End date: 2012-05-09
Bortezomib
Indication: Glioblastoma Multiforme
Start date: 2010-04-27
End date: 2010-07-13
Other drugs received by patient: Keppra; Ascorbic Acid; Celexa; Zinc Sulfate; Finasteride; Provigil
Possible Avastin side effects in female
Reported by a consumer/non-health professional from Australia on 2012-08-27
Patient: female
Reactions: Disease Progression
Drug(s) suspected as cause:
Avastin
Possible Avastin side effects in male
Reported by a physician from Japan on 2012-08-27
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: White Blood Cell Count Decreased, Gastrointestinal Haemorrhage, Dyspnoea, Haemoptysis, Cardio-Respiratory Arrest, Depressed Level of Consciousness, Pulmonary Thrombosis, Epistaxis, Oxygen Saturation Decreased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aspirin
Dosage: dose form: enteric coating drug
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Warfarin Sodium
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Avastin
Indication: non-Small Cell Lung Cancer
Start date: 2010-08-10
End date: 2010-08-10
Other drugs received by patient: Amaryl; Transamine CAP; Carboplatin; Coniel; Allopurinol; Lasix; Adona; Candesartan Cilexetil; Aldactone; Basen; Gosha-Jinki-GAN; Paclitaxel
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Brain Neoplasm
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Tarceva
Indication: Product Used FOR Unknown Indication
Avastin
Indication: Brain Neoplasm Malignant
Possible Avastin side effects in female
Reported by a physician from United States on 2012-08-27
Patient: female, weighing 84.9 kg (186.8 pounds)
Reactions: Breast Infection
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Methotrexate
Administration route: Oral
Indication: Breast Cancer
Start date: 2012-06-15
End date: 2012-08-01
Avastin
Dosage: last dose prior to event - 27/jul/2012
Indication: Breast Cancer
Start date: 2012-06-15
Cyclophosphamide
Administration route: Oral
Indication: Breast Cancer
Start date: 2012-06-15
End date: 2012-08-01
Possible Avastin side effects in female
Reported by a physician from United States on 2012-08-27
Patient: female
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Indication: Bile Duct Cancer
Tarceva
Indication: Product Used FOR Unknown Indication
Possible Avastin side effects in male
Reported by a physician from Algeria on 2012-08-27
Patient: male
Reactions: Disease Progression
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Indication: Glioblastoma
Irinotecan Hydrochloride
Indication: Glioblastoma
Possible Avastin side effects in female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-27
Patient: female
Reactions: Glioblastoma, White Blood Cell Count Decreased, Monocyte Count Decreased, Nausea, Alopecia, Platelet Count Decreased, Neutrophil Count Decreased
Drug(s) suspected as cause:
Avastin
Indication: Glioblastoma
Start date: 2012-03-23
Avastin
Start date: 2012-07-25
Avastin
Start date: 2012-04-04
Avastin
Start date: 2012-05-06
Other drugs received by patient: Valproic Acid
Possible Avastin side effects in
Reported by a physician from Netherlands on 2012-08-27
Patient:
Reactions: Disease Progression
Drug(s) suspected as cause:
Carboplatin
Indication: non-Small Cell Lung Cancer
Pemetrexed
Indication: non-Small Cell Lung Cancer
Avastin
Indication: non-Small Cell Lung Cancer
Possible Avastin side effects in female
Reported by a physician from United States on 2012-08-27
Patient: female
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Indication: Hepatic Neoplasm Malignant
Avastin
Indication: Renal Cancer
Possible Avastin side effects in 72 year old female
Reported by a physician from United States on 2012-08-27
Patient: 72 year old female, weighing 71.6 kg (157.5 pounds)
Reactions: Ventricular Arrhythmia
Drug(s) suspected as cause:
Carboplatin
Dosage: auc 6 (cycle 1-6),6th cycle completed on 16/feb/2012
Indication: Ovarian Epithelial Cancer
Start date: 2011-11-23
Avastin
Dosage: 15 mg/kg iv over 30-90 minutes on day 1 on 2 cycle onwards
Indication: Ovarian Epithelial Cancer
Paclitaxel
Dosage: 175 mg/m2 over 3 hrs on day 1(cycle 1-6), 6th cycle completed on 16/feb/2012
Indication: Ovarian Epithelial Cancer
Start date: 2011-11-23
Ipratropium Bromide
Indication: Product Used FOR Unknown Indication
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Possible Avastin side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Tarceva
Indication: Bile Duct Cancer
Tarceva
Indication: Pancreatic Carcinoma
Start date: 2005-06-01
Avastin
Indication: Pancreatic Carcinoma
Start date: 2005-06-23
Possible Avastin side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-27
Patient: female
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Tarceva
Indication: Metastases To Nervous System
Avastin
Indication: Product Used FOR Unknown Indication
Tarceva
Indication: Lung Neoplasm Malignant
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