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Anafranil (Clomipramine) - Hepatic Failure - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Hepatic Failure (7)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Anafranil (Clomipramine) where reactions include hepatic failure. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Anafranil side effects in 52 year old male

Reported by a consumer/non-health professional from Italy on 2012-04-18

Patient: 52 year old male

Reactions: Jaundice, Liver Injury, Cytolytic Hepatitis, Blood Albumin Decreased, Hepatic Failure, Condition Aggravated, Alcoholic Liver Disease, Ascites, Hepatosplenomegaly, Hepatic Cirrhosis, Prothrombin Level Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Anafranil
    Dosage: 0.25 mg, tid
    Administration route: Oral
    Indication: Depression
    Start date: 2012-01-01
    End date: 2012-01-21

Escitalopram
    Dosage: 20 mg, daily
    Administration route: Oral
    Indication: Depression
    Start date: 2011-10-01
    End date: 2012-01-01

Alprazolam
    Dosage: 0.25 mg, tid
    Administration route: Oral
    Indication: Mental Disorder
    End date: 2012-01-21

Rasilez HCT
    Dosage: 1 df, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-01-21

Zyprexa
    Dosage: 5 mg, daily
    Administration route: Oral
    Indication: Depression
    Start date: 2011-11-23
    End date: 2012-01-05

Other drugs received by patient: Prazepam



Possible Anafranil side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-04-18

Patient: 52 year old male

Reactions: Jaundice, Liver Injury, Cytolytic Hepatitis, Condition Aggravated, Blood Albumin Decreased, Hepatic Failure, Alcoholic Liver Disease, Ascites, Hepatosplenomegaly, Hepatic Cirrhosis, Prothrombin Level Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Anafranil
    Dosage: 0.25 mg, tid
    Administration route: Oral
    Indication: Depression
    Start date: 2012-01-01
    End date: 2012-01-21

Zyprexa
    Dosage: 5 mg, daily
    Administration route: Oral
    Indication: Depression
    Start date: 2011-11-23
    End date: 2012-01-05

Alprazolam
    Dosage: 0.25 mg, tid
    Administration route: Oral
    Indication: Mental Disorder
    End date: 2012-01-21

Rasilez HCT
    Dosage: 1 df, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-01-21

Escitalopram
    Dosage: 20 mg, daily
    Administration route: Oral
    Indication: Depression
    Start date: 2011-10-01
    End date: 2012-01-01

Other drugs received by patient: Prazepam



Possible Anafranil side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-04-12

Patient: 52 year old male

Reactions: Liver Injury, Jaundice, Cytolytic Hepatitis, Condition Aggravated, Hepatic Failure, Blood Albumin Decreased, Prothrombin Time Prolonged, Alcoholic Liver Disease, Ascites, Hepatic Enzyme Increased, Gynaecomastia, Spider Vein, Hepatomegaly, Hepatosplenomegaly, Hepatic Cirrhosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Anafranil
    Dosage: 37.5 mg, qd
    End date: 2012-01-21

Escitalopram
    Dosage: 20 mg, qd
    Indication: Depression
    End date: 2012-01-01

Zyprexa
    Dosage: 5 mg, qd
    Indication: Depression
    End date: 2012-01-05

Rasilez HCT
    Dosage: 1 df, unk
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-01-21

Alprazolam
    Dosage: 0.25 mg, tid
    End date: 2012-01-21

Other drugs received by patient: Prazepam



Possible Anafranil side effects in 52 year old male

Reported by a physician from France on 2012-04-12

Patient: 52 year old male

Reactions: Liver Injury, Jaundice, Cytolytic Hepatitis, Condition Aggravated, Hepatic Failure, Alcoholic Liver Disease, Ascites, Hepatic Enzyme Increased, Gynaecomastia, Hepatomegaly, Hepatic Cirrhosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rasilez HCT
    Dosage: 1 df, unk
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-01-21

Escitalopram Oxalate
    Dosage: 20 mg, qd
    Indication: Depression
    End date: 2012-01-01

Anafranil
    Dosage: 37.5 mg, qd
    End date: 2012-01-21

Alprazolam
    Dosage: 0.25 mg, tid
    End date: 2012-01-21

Zyprexa
    Dosage: 5 mg, qd
    Indication: Depression
    End date: 2012-01-05

Other drugs received by patient: Prazepam



Possible Anafranil side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-04-12

Patient: 52 year old male

Reactions: Liver Injury, Jaundice, Cytolytic Hepatitis, Condition Aggravated, Blood Albumin Decreased, Hepatic Failure, Alcoholic Liver Disease, Ascites, Prothrombin Level Decreased, Hepatic Cirrhosis, Hepatosplenomegaly

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyprexa
    Dosage: 5 mg, daily
    Administration route: Oral
    Indication: Depression
    Start date: 2011-11-23
    End date: 2012-01-05

Anafranil
    Dosage: 0.25 mg, tid
    Administration route: Oral
    Indication: Depression
    Start date: 2012-01-01
    End date: 2012-01-21

Rasilez HCT
    Dosage: 1 df, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-01-21

Alprazolam
    Dosage: 0.25 mg, tid
    Administration route: Oral
    Indication: Mental Disorder
    End date: 2012-01-21

Escitalopram
    Dosage: 20 mg, daily
    Administration route: Oral
    Indication: Depression
    Start date: 2011-10-01
    End date: 2012-01-01

Other drugs received by patient: Prazepam



Possible Anafranil side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-04-12

Patient: 52 year old male

Reactions: Liver Injury, Jaundice, Cytolytic Hepatitis, Blood Albumin Decreased, Condition Aggravated, Hepatic Failure, Alcoholic Liver Disease, Ascites, Hepatosplenomegaly, Hepatic Cirrhosis, Prothrombin Level Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Escitalopram
    Dosage: 20 mg, daily
    Administration route: Oral
    Indication: Depression
    Start date: 2011-10-01
    End date: 2012-01-01

Anafranil
    Dosage: 0.25 mg, tid
    Administration route: Oral
    Indication: Depression
    Start date: 2012-01-01
    End date: 2012-01-21

Alprazolam
    Dosage: 0.25 mg, tid
    Administration route: Oral
    Indication: Mental Disorder
    End date: 2012-01-21

Zyprexa
    Dosage: 5 mg, daily
    Administration route: Oral
    Indication: Depression
    Start date: 2011-11-23
    End date: 2012-01-05

Rasilez HCT
    Dosage: 1 df, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-01-21

Other drugs received by patient: Prazepam



Possible Anafranil side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-04-11

Patient: 52 year old male

Reactions: Jaundice, Condition Aggravated, Hepatic Failure, Hepatic Enzyme Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyprexa
    Dosage: 5 mg
    Administration route: Oral
    Indication: Depression
    Start date: 2011-11-23
    End date: 2012-01-05

Rasilez HCT
    Dosage: 150mg/12.5 mg daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-01-21

Alprazolam
    Dosage: 0.75 mg
    Administration route: Oral
    Indication: Mental Disorder
    End date: 2012-01-21

Escitalopram
    Dosage: 20 mg
    Administration route: Oral
    Indication: Depression
    Start date: 2011-10-01
    End date: 2012-01-01

Anafranil
    Dosage: 37.5 mg
    Administration route: Oral
    Indication: Depression
    Start date: 2012-01-01
    End date: 2012-01-21

Other drugs received by patient: Prazepam

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