DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Amphotericin B (Amphotericin B) - Renal Failure Acute - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Renal Failure Acute (14)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Amphotericin B where reactions include renal failure acute. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Amphotericin B side effects in 33 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-01

Patient: 33 year old male, weighing 93.0 kg (204.6 pounds)

Reactions: Lactobacillus Infection, Blood PH Increased, Tachycardia, Blood PH Decreased, Device Related Infection, Scleral Haemorrhage, Bacterial Sepsis, Acute Respiratory Distress Syndrome, Bone Marrow Failure, Blood Bicarbonate Increased, Acute Respiratory Failure, Renal Failure Acute, Febrile Neutropenia, Haemodialysis, Alopecia, Treatment Failure, Base Excess Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vancomycin
    Indication: Product Used FOR Unknown Indication

Daunorubicin HCL
    Dosage: see image
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-03-30
    End date: 2012-04-01

Daunorubicin HCL
    Dosage: see image
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-04-14
    End date: 2012-04-16

Imipenem and Cilastatin
    Dosage: 1000 mg, q8 hours intravenous (not otherwise specified)
    Indication: Infection
    Start date: 2012-05-07
    End date: 2012-05-28

Caspofungin Acetate
    Dosage: see image
    Indication: Infection
    Start date: 2012-04-09

Caspofungin Acetate
    Dosage: see image
    Indication: Infection
    Start date: 2012-04-08
    End date: 2012-04-08

Caspofungin Acetate
    Dosage: see image
    Indication: Infection
    Start date: 2012-05-20
    End date: 2012-05-22

Voriconazole
    Dosage: 522 mg, q12 hours, intravenous (not otherwise specified)
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-08
    End date: 2012-05-08

Penicillin G
    Dosage: 24000000 u, q24 hrs intravenous (not otherwise specified)
    Indication: Infection
    Start date: 2012-05-04
    End date: 2012-05-09

Amphotericin B
    Dosage: 450 mg, uid/qd, intravenous (not otherwise specified)
    Indication: Fungal Infection
    Start date: 2012-05-06
    End date: 2012-05-08

Amphotericin B
    Dosage: 450 mg, uid/qd, intravenous (not otherwise specified)
    Indication: Infection Prophylaxis
    Start date: 2012-05-06
    End date: 2012-05-08

Aztreonam
    Dosage: see image
    Indication: Bacterial Infection
    Start date: 2012-05-06
    End date: 2012-05-07

Aztreonam
    Dosage: see image
    Indication: Bacterial Infection
    Start date: 2012-04-09
    End date: 2012-04-10

Cefepime
    Dosage: 2 g, q8 hours, intravenous (not otherwise specified) ; intravenous (not otherwise specified)
    Indication: Infection
    Start date: 2012-03-29
    End date: 2012-04-10

Cefepime
    Dosage: 2 g, q8 hours, intravenous (not otherwise specified) ; intravenous (not otherwise specified)
    Indication: Infection
    Start date: 2012-06-02
    End date: 2012-06-05

(Investigational Drug)
    Dosage: 60 mg, uid/qd, oral ; 60 mg, uid/qd, oral
    Administration route: Oral
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-04-17
    End date: 2012-04-23

(Investigational Drug)
    Dosage: 60 mg, uid/qd, oral ; 60 mg, uid/qd, oral
    Administration route: Oral
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-04-02
    End date: 2012-04-08

Cytarabine
    Dosage: see image
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-04-14
    End date: 2012-04-20

Cytarabine
    Dosage: see image
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-03-30
    End date: 2012-04-05

Other drugs received by patient: Ondansetron; Seroquel; Percocet; Nystatin; Zyloprim; Acetaminophen; Calcium Carbonate; Lorazepam; Xanax; Allopurinol; Calcium Gluconate; Ibuprofen; Hydroxyzine Pamoate; Celexa



Possible Amphotericin B side effects in 43 year old male

Reported by a health professional (non-physician/pharmacist) on 2012-06-08

Patient: 43 year old male

Reactions: Liver Injury, Bronchopulmonary Aspergillosis, Neutropenic Sepsis, Cholestasis, H1n1 Influenza, Haemodialysis, Cardio-Respiratory Arrest, Hallucination, Visual, Cardiac Failure, Mycobacterium Fortuitum Infection, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ciprofloxacin
    Dosage: 1000 mg (500 mg, 2 in 1 d),
    Indication: Mycobacterium Fortuitum Infection

Clarithromycin
    Dosage: 1000 mg (500 mg, 2 in 1 d),
    Indication: Mycobacterium Fortuitum Infection

Teicoplanin (Teicoplanin)
    Dosage: 400 mg (400 mg, 1 in 1 d), parenteral
    Indication: Product Used FOR Unknown Indication

Cyclophosphamide
    Dosage: 100 mg (100 mg, 1 in 1 d), oral
    Administration route: Oral
    Indication: Immunosuppression

Oseltamivir Phosphate
    Dosage: 150 mg (75 mg, 2 in 1 d), parenteral
    Indication: Product Used FOR Unknown Indication

Prednisolone
    Dosage: 60 mg,
    Indication: Immunosuppression

Voriconazole
    Indication: Aspergillosis

Meropenem
    Dosage: 2 gm (1 gm, 2 in 1 d), parenteral
    Indication: Product Used FOR Unknown Indication

Amphotericin B
    Indication: Aspergillosis



Possible Amphotericin B side effects in 43 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-05

Patient: 43 year old male

Reactions: Liver Injury, Right Ventricular Failure, Dyspnoea, Haemoptysis, Cholestasis, Cardio-Respiratory Arrest, Sepsis Syndrome, Respiratory Failure, Aspergillosis, Neutropenia, Mycobacterium Fortuitum Infection, Renal Failure Acute, Influenza A Virus Test Positive

Adverse event resulted in: death

Drug(s) suspected as cause:
Prednisolone
    Dosage: 60 mg, daily
    Administration route: Oral
    Indication: Renal Vasculitis

Ciprofloxacin HCL
    Dosage: 500 mg, bid
    Indication: Mycobacterium Fortuitum Infection

Meropenem
    Dosage: 1 g, bid
    Indication: Sepsis Syndrome

Amikacin
    Indication: Mycobacterium Fortuitum Infection

Amphotericin B
    Indication: Aspergillosis

Prednisolone
    Indication: Pulmonary Vasculitis

Voriconazole
    Dosage: unk
    Indication: Aspergillosis

Cyclophosphamide
    Indication: Pulmonary Vasculitis

Oseltamivir
    Dosage: 75 mg, bid
    Indication: Sepsis Syndrome

Clarithromycin
    Dosage: 500 mg, bid
    Indication: Mycobacterium Fortuitum Infection

Teicoplanin
    Dosage: 400 mg, daily
    Indication: Sepsis Syndrome

Cyclophosphamide
    Dosage: 100 mg, daily
    Administration route: Oral
    Indication: Renal Vasculitis



Possible Amphotericin B side effects in 47 year old female

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-05-30

Patient: 47 year old female, weighing 68.0 kg (149.6 pounds)

Reactions: Hepatomegaly, Respiratory Disorder, Respiratory Tract Haemorrhage, Candidiasis, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Tretinoin
    Dosage: 40 mg/m2/day continuously
    Administration route: Oral
    Indication: Acute Promyelocytic Leukaemia

Metamizole
    Dosage: 500 mg
    Administration route: Oral
    Indication: Febrile Neutropenia

Fluconazole
    Dosage: 200 mg/day
    Administration route: Oral
    Indication: Candidiasis

Mitoxantrone
    Dosage: 20 mg/m2/day
    Indication: Acute Promyelocytic Leukaemia

Amphotericin B
    Dosage: 30 mg/day, 6 hours of infusion
    Indication: Candidiasis

Cytarabine
    Dosage: 370 mg/m2/day
    Indication: Acute Promyelocytic Leukaemia

Cefepime
    Dosage: 2 g, every eight hours
    Indication: Febrile Neutropenia

Other drugs received by patient: Meropenem; Methotrexate; Tretinoin



Possible Amphotericin B side effects in male

Reported by a physician from Korea, Republic of on 2012-05-10

Patient: male, weighing 55.0 kg (121.0 pounds)

Reactions: Pneumonia Fungal, Fatigue, Aspergillus Test Positive, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Pertuzumab
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Amphotericin B
    Indication: Product Used FOR Unknown Indication

Herceptin
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Cisplatin
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Xeloda
    Dosage: date of most recent dose prior to sae: 31/jan/2012
    Administration route: Oral
    Indication: Gastric Cancer
    Start date: 2011-12-21

Voriconazole
    Indication: Product Used FOR Unknown Indication



Possible Amphotericin B side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-04-13

Patient: 47 year old male

Reactions: Respiratory Tract Haemorrhage, Mouth Ulceration, Pyrexia, Hypokalaemia, Weight Increased, Hepatomegaly, Proteinuria, Haemoglobinuria, Blood Creatinine Increased, Renal Failure Acute, Dyspnoea, Blood Urea Increased, Urine Output Decreased, Haematuria, Diarrhoea, Oral Disorder, Oliguria, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluconazole
    Dosage: 200 mg, qd
    Administration route: Oral

Tretinoin
    Administration route: Oral

Amphotericin B
    Dosage: 30 mg, qd

Cefepime
    Dosage: 2 g, qd
    Indication: Febrile Neutropenia

Other drugs received by patient: Meropenem; Mitoxantrone; Cytarabine; Dipyrone TAB; Dexamethasone



Possible Amphotericin B side effects in male

Reported by a individual with unspecified qualification from Korea, Republic of on 2012-03-25

Patient: male, weighing 55.0 kg (121.0 pounds)

Reactions: Pneumonia Fungal, Fatigue, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Pertuzumab
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Herceptin
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Amphotericin B
    Indication: Product Used FOR Unknown Indication

Xeloda
    Dosage: date of most recent dose prior to sae: 31/jan/2012
    Administration route: Oral
    Indication: Gastric Cancer
    Start date: 2011-12-21

Cisplatin
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Voriconazole
    Indication: Product Used FOR Unknown Indication



Possible Amphotericin B side effects in 47 year old female

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-09

Patient: 47 year old female, weighing 69.0 kg (151.8 pounds)

Reactions: Pneumonia Klebsiella, Hepatomegaly, Diarrhoea, Drug Interaction, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: for 7 days
    Administration route: Oral

Mitoxantrone
    Dosage: for 3 days
    Administration route: Oral

Amphotericin B
    Dosage: 6:0 on day13,stopped on day 21

Other drugs received by patient possibly interacting with the suspect drug:
Cefepime
    Dosage: every 8:0,emperic therapy
    Indication: Anaemia

Tretinoin
    Dosage: continued until day 16,restarted from day 37 20mg/m2
    Administration route: Oral

Cefepime
    Dosage: every 8:0,emperic therapy
    Indication: Thrombocytopenia

Fluconazole
    Administration route: Oral

Cefepime
    Dosage: every 8:0,emperic therapy
    Indication: Febrile Neutropenia

Other drugs received by patient: Dipyrone TAB; Dipyrone TAB; Methotrexate; Dexamethasone; Dipyrone TAB



Possible Amphotericin B side effects in 47 year old female

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-08

Patient: 47 year old female, weighing 68.8 kg (151.4 pounds)

Reactions: Tachycardia, Hypokalaemia, Weight Increased, Hepatomegaly, Bronchospasm, Thrombocytopenia, Renal Failure Acute, Dyspnoea, Pneumonia, Mouth Haemorrhage, Anaemia, Pulmonary Haemorrhage, Urethral Haemorrhage, Retinoic Acid Syndrome, Renal Impairment, Diarrhoea, Respiratory Failure, Oliguria, Asthenia, Leukopenia, Infusion Related Reaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluconazole
    Dosage: 200 mg/day orally
    Administration route: Oral
    Indication: Candidiasis

Cytarabine
    Dosage: 370 mg/m2/day ev, for 7 days

Cefepime
    Dosage: 2 g every eight hours as empiric therapy, intravenous
    Indication: Febrile Neutropenia

Dipyrone INJ
    Dosage: 500 mg orally
    Administration route: Oral
    Indication: Febrile Neutropenia

ALL Transretinoic Acid (All Transretinoic Acid)
    Dosage: 40 mg/m2/day orally, 20 mg/m2/day orally
    Administration route: Oral
    Indication: Chemotherapy

Amphotericin B
    Dosage: 30 mg/day (6 hours of infusion), 240 mg (cumulative dose)
    Indication: Candidiasis

Mitoxantrone
    Dosage: 20 mg/m2/day ev, for 3 days
    Indication: Chemotherapy

Meropenem
    Dosage: 1 g ev, every eight hours



Possible Amphotericin B side effects in 47 year old female

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-07

Patient: 47 year old female

Reactions: Dyspnoea, Hepatomegaly, Respiratory Tract Haemorrhage, Candidiasis, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Tretinoin
    Dosage: unk
    Administration route: Oral
    Indication: Acute Promyelocytic Leukaemia

Mitoxantrone
    Dosage: unk
    Indication: Acute Promyelocytic Leukaemia

Fluconazole
    Dosage: 200 mg/day
    Administration route: Oral
    Indication: Candidiasis

Metamizole
    Dosage: unk
    Indication: Acute Promyelocytic Leukaemia

Amphotericin B
    Dosage: 30 mg/day 6:0
    Indication: Product Used FOR Unknown Indication

Cefepime
    Dosage: 2 g, every 8:0
    Indication: Acute Promyelocytic Leukaemia

Cytarabine
    Dosage: unk
    Indication: Acute Promyelocytic Leukaemia

Other drugs received by patient: Meropenem; Methotrexate; Tretinoin



Possible Amphotericin B side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-03

Patient: 47 year old male

Reactions: Respiratory Tract Haemorrhage, Mouth Ulceration, Pyrexia, Hypokalaemia, Weight Increased, Hepatomegaly, Proteinuria, Haemoglobinuria, Blood Creatinine Increased, Renal Failure Acute, Blood Urea Increased, Dyspnoea, Urine Output Decreased, Haematuria, Diarrhoea, Oral Disorder, Oliguria, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amphotericin B
    Dosage: 30 mg, qd

Fluconazole
    Dosage: 200 mg, qd
    Administration route: Oral

Cefepime
    Dosage: 2 g, qd
    Indication: Febrile Neutropenia

Tretinoin
    Administration route: Oral

Other drugs received by patient: Dipyrone TAB; Mitoxantrone; Cytarabine; Meropenem; Dexamethasone



Possible Amphotericin B side effects in male

Reported by a individual with unspecified qualification from Korea, Republic of on 2012-02-27

Patient: male, weighing 55.0 kg (121.0 pounds)

Reactions: Pneumonia Fungal, Fatigue, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Voriconazole
    Indication: Product Used FOR Unknown Indication

Xeloda
    Dosage: date of most recent dose prior to sae: 31/jan/2012
    Administration route: Oral
    Indication: Gastric Cancer
    Start date: 2011-12-21

Amphotericin B
    Indication: Product Used FOR Unknown Indication

Pertuzumab
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Herceptin
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Cisplatin
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21



Possible Amphotericin B side effects in 34 year old female

Reported by a health professional (non-physician/pharmacist) from Brazil on 2011-11-18

Patient: 34 year old female, weighing 56.0 kg (123.2 pounds)

Reactions: Hyperpyrexia, Bronchopneumonia, Wheezing, Pyrexia, Multi-Organ Failure, Oral Candidiasis, Pulmonary Congestion, Cough, Renal Failure Acute, Oxygen Saturation Decreased, Dyspnoea, Metabolic Acidosis, Maternal Exposure During Pregnancy, Respiratory Distress, Cardiogenic Shock, Agranulocytosis, Fungal Infection, Oliguria, Systemic Inflammatory Response Syndrome, Neutropenia, Fusarium Infection, Septic Shock, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nitrofurantoin
    Indication: Infection Prophylaxis

Ganciclovir
    Indication: Fusarium Infection

Nystatin
    Administration route: Oral
    Indication: Fusarium Infection

Amphotericin B

Ceftriaxone

Nystatin
    Administration route: Oral

Metamizole Sodium
    Indication: Tracheobronchitis

Ceftriaxone
    Indication: Pyelonephritis

Ceftriaxone
    Indication: Tracheobronchitis

Ceftriaxone

Clarithromycin
    Indication: Fusarium Infection

Imipenem
    Indication: Tracheobronchitis

Imipenem

Propranolol HCL
    Indication: Mitral Valve Stenosis

Furosemide
    Indication: Pulmonary Congestion

Nystatin
    Administration route: Oral
    Indication: Tracheobronchitis

Imipenem
    Indication: Fusarium Infection

Ganciclovir

Vancomycin
    Indication: Tracheobronchitis

Clarithromycin
    Indication: Tracheobronchitis

Vancomycin

Clarithromycin

Ganciclovir
    Indication: Tracheobronchitis

Vancomycin
    Indication: Fusarium Infection

Amphotericin B
    Indication: Tracheobronchitis

Amphotericin B
    Indication: Fusarium Infection

Other drugs received by patient: Oxytocin; Dobutamine HCL; Vitamin TAB; Sodium Chloride; Nitric Oxide



Possible Amphotericin B side effects in 48 year old male

Reported by a physician from Germany on 2011-10-03

Patient: 48 year old male

Reactions: Overdose, Vomiting, Medication Error, Anaemia, Haemolysis, Renal Failure Acute

Drug(s) suspected as cause:
Amphotericin B
    Indication: Cryptococcosis
    Start date: 2011-08-13

Ambisome
    Start date: 2011-08-08

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017