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Index of reports
> Cases with Renal Failure Acute (14)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Amphotericin B where reactions include renal failure acute. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Amphotericin B side effects in 33 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-01
Patient: 33 year old male, weighing 93.0 kg (204.6 pounds)
Reactions: Lactobacillus Infection, Blood PH Increased, Tachycardia, Blood PH Decreased, Device Related Infection, Scleral Haemorrhage, Bacterial Sepsis, Acute Respiratory Distress Syndrome, Bone Marrow Failure, Blood Bicarbonate Increased, Acute Respiratory Failure, Renal Failure Acute, Febrile Neutropenia, Haemodialysis, Alopecia, Treatment Failure, Base Excess Decreased
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Vancomycin
Indication: Product Used FOR Unknown Indication
Daunorubicin HCL
Dosage: see image
Indication: Acute Myeloid Leukaemia
Start date: 2012-03-30
End date: 2012-04-01
Daunorubicin HCL
Dosage: see image
Indication: Acute Myeloid Leukaemia
Start date: 2012-04-14
End date: 2012-04-16
Imipenem and Cilastatin
Dosage: 1000 mg, q8 hours intravenous (not otherwise specified)
Indication: Infection
Start date: 2012-05-07
End date: 2012-05-28
Caspofungin Acetate
Dosage: see image
Indication: Infection
Start date: 2012-04-09
Caspofungin Acetate
Dosage: see image
Indication: Infection
Start date: 2012-04-08
End date: 2012-04-08
Caspofungin Acetate
Dosage: see image
Indication: Infection
Start date: 2012-05-20
End date: 2012-05-22
Voriconazole
Dosage: 522 mg, q12 hours, intravenous (not otherwise specified)
Indication: Product Used FOR Unknown Indication
Start date: 2012-05-08
End date: 2012-05-08
Penicillin G
Dosage: 24000000 u, q24 hrs intravenous (not otherwise specified)
Indication: Infection
Start date: 2012-05-04
End date: 2012-05-09
Amphotericin B
Dosage: 450 mg, uid/qd, intravenous (not otherwise specified)
Indication: Fungal Infection
Start date: 2012-05-06
End date: 2012-05-08
Amphotericin B
Dosage: 450 mg, uid/qd, intravenous (not otherwise specified)
Indication: Infection Prophylaxis
Start date: 2012-05-06
End date: 2012-05-08
Aztreonam
Dosage: see image
Indication: Bacterial Infection
Start date: 2012-05-06
End date: 2012-05-07
Aztreonam
Dosage: see image
Indication: Bacterial Infection
Start date: 2012-04-09
End date: 2012-04-10
Cefepime
Dosage: 2 g, q8 hours, intravenous (not otherwise specified) ; intravenous (not otherwise specified)
Indication: Infection
Start date: 2012-03-29
End date: 2012-04-10
Cefepime
Dosage: 2 g, q8 hours, intravenous (not otherwise specified) ; intravenous (not otherwise specified)
Indication: Infection
Start date: 2012-06-02
End date: 2012-06-05
(Investigational Drug)
Dosage: 60 mg, uid/qd, oral ; 60 mg, uid/qd, oral
Administration route: Oral
Indication: Acute Myeloid Leukaemia
Start date: 2012-04-17
End date: 2012-04-23
(Investigational Drug)
Dosage: 60 mg, uid/qd, oral ; 60 mg, uid/qd, oral
Administration route: Oral
Indication: Acute Myeloid Leukaemia
Start date: 2012-04-02
End date: 2012-04-08
Cytarabine
Dosage: see image
Indication: Acute Myeloid Leukaemia
Start date: 2012-04-14
End date: 2012-04-20
Cytarabine
Dosage: see image
Indication: Acute Myeloid Leukaemia
Start date: 2012-03-30
End date: 2012-04-05
Other drugs received by patient: Ondansetron; Seroquel; Percocet; Nystatin; Zyloprim; Acetaminophen; Calcium Carbonate; Lorazepam; Xanax; Allopurinol; Calcium Gluconate; Ibuprofen; Hydroxyzine Pamoate; Celexa
Possible Amphotericin B side effects in 43 year old male
Reported by a health professional (non-physician/pharmacist) on 2012-06-08
Patient: 43 year old male
Reactions: Liver Injury, Bronchopulmonary Aspergillosis, Neutropenic Sepsis, Cholestasis, H1n1 Influenza, Haemodialysis, Cardio-Respiratory Arrest, Hallucination, Visual, Cardiac Failure, Mycobacterium Fortuitum Infection, Renal Failure Acute
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Ciprofloxacin
Dosage: 1000 mg (500 mg, 2 in 1 d),
Indication: Mycobacterium Fortuitum Infection
Clarithromycin
Dosage: 1000 mg (500 mg, 2 in 1 d),
Indication: Mycobacterium Fortuitum Infection
Teicoplanin (Teicoplanin)
Dosage: 400 mg (400 mg, 1 in 1 d), parenteral
Indication: Product Used FOR Unknown Indication
Cyclophosphamide
Dosage: 100 mg (100 mg, 1 in 1 d), oral
Administration route: Oral
Indication: Immunosuppression
Oseltamivir Phosphate
Dosage: 150 mg (75 mg, 2 in 1 d), parenteral
Indication: Product Used FOR Unknown Indication
Prednisolone
Dosage: 60 mg,
Indication: Immunosuppression
Voriconazole
Indication: Aspergillosis
Meropenem
Dosage: 2 gm (1 gm, 2 in 1 d), parenteral
Indication: Product Used FOR Unknown Indication
Amphotericin B
Indication: Aspergillosis
Possible Amphotericin B side effects in 43 year old male
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-05
Patient: 43 year old male
Reactions: Liver Injury, Right Ventricular Failure, Dyspnoea, Haemoptysis, Cholestasis, Cardio-Respiratory Arrest, Sepsis Syndrome, Respiratory Failure, Aspergillosis, Neutropenia, Mycobacterium Fortuitum Infection, Renal Failure Acute, Influenza A Virus Test Positive
Adverse event resulted in: death
Drug(s) suspected as cause:
Prednisolone
Dosage: 60 mg, daily
Administration route: Oral
Indication: Renal Vasculitis
Ciprofloxacin HCL
Dosage: 500 mg, bid
Indication: Mycobacterium Fortuitum Infection
Meropenem
Dosage: 1 g, bid
Indication: Sepsis Syndrome
Amikacin
Indication: Mycobacterium Fortuitum Infection
Amphotericin B
Indication: Aspergillosis
Prednisolone
Indication: Pulmonary Vasculitis
Voriconazole
Dosage: unk
Indication: Aspergillosis
Cyclophosphamide
Indication: Pulmonary Vasculitis
Oseltamivir
Dosage: 75 mg, bid
Indication: Sepsis Syndrome
Clarithromycin
Dosage: 500 mg, bid
Indication: Mycobacterium Fortuitum Infection
Teicoplanin
Dosage: 400 mg, daily
Indication: Sepsis Syndrome
Cyclophosphamide
Dosage: 100 mg, daily
Administration route: Oral
Indication: Renal Vasculitis
Possible Amphotericin B side effects in 47 year old female
Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-05-30
Patient: 47 year old female, weighing 68.0 kg (149.6 pounds)
Reactions: Hepatomegaly, Respiratory Disorder, Respiratory Tract Haemorrhage, Candidiasis, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Tretinoin
Dosage: 40 mg/m2/day continuously
Administration route: Oral
Indication: Acute Promyelocytic Leukaemia
Metamizole
Dosage: 500 mg
Administration route: Oral
Indication: Febrile Neutropenia
Fluconazole
Dosage: 200 mg/day
Administration route: Oral
Indication: Candidiasis
Mitoxantrone
Dosage: 20 mg/m2/day
Indication: Acute Promyelocytic Leukaemia
Amphotericin B
Dosage: 30 mg/day, 6 hours of infusion
Indication: Candidiasis
Cytarabine
Dosage: 370 mg/m2/day
Indication: Acute Promyelocytic Leukaemia
Cefepime
Dosage: 2 g, every eight hours
Indication: Febrile Neutropenia
Other drugs received by patient: Meropenem; Methotrexate; Tretinoin
Possible Amphotericin B side effects in male
Reported by a physician from Korea, Republic of on 2012-05-10
Patient: male, weighing 55.0 kg (121.0 pounds)
Reactions: Pneumonia Fungal, Fatigue, Aspergillus Test Positive, Renal Failure Acute
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Pertuzumab
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Amphotericin B
Indication: Product Used FOR Unknown Indication
Herceptin
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Cisplatin
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Xeloda
Dosage: date of most recent dose prior to sae: 31/jan/2012
Administration route: Oral
Indication: Gastric Cancer
Start date: 2011-12-21
Voriconazole
Indication: Product Used FOR Unknown Indication
Possible Amphotericin B side effects in 47 year old male
Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-04-13
Patient: 47 year old male
Reactions: Respiratory Tract Haemorrhage, Mouth Ulceration, Pyrexia, Hypokalaemia, Weight Increased, Hepatomegaly, Proteinuria, Haemoglobinuria, Blood Creatinine Increased, Renal Failure Acute, Dyspnoea, Blood Urea Increased, Urine Output Decreased, Haematuria, Diarrhoea, Oral Disorder, Oliguria, Asthenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Fluconazole
Dosage: 200 mg, qd
Administration route: Oral
Tretinoin
Administration route: Oral
Amphotericin B
Dosage: 30 mg, qd
Cefepime
Dosage: 2 g, qd
Indication: Febrile Neutropenia
Other drugs received by patient: Meropenem; Mitoxantrone; Cytarabine; Dipyrone TAB; Dexamethasone
Possible Amphotericin B side effects in male
Reported by a individual with unspecified qualification from Korea, Republic of on 2012-03-25
Patient: male, weighing 55.0 kg (121.0 pounds)
Reactions: Pneumonia Fungal, Fatigue, Renal Failure Acute
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Pertuzumab
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Herceptin
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Amphotericin B
Indication: Product Used FOR Unknown Indication
Xeloda
Dosage: date of most recent dose prior to sae: 31/jan/2012
Administration route: Oral
Indication: Gastric Cancer
Start date: 2011-12-21
Cisplatin
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Voriconazole
Indication: Product Used FOR Unknown Indication
Possible Amphotericin B side effects in 47 year old female
Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-09
Patient: 47 year old female, weighing 69.0 kg (151.8 pounds)
Reactions: Pneumonia Klebsiella, Hepatomegaly, Diarrhoea, Drug Interaction, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Cytarabine
Dosage: for 7 days
Administration route: Oral
Mitoxantrone
Dosage: for 3 days
Administration route: Oral
Amphotericin B
Dosage: 6:0 on day13,stopped on day 21
Other drugs received by patient possibly interacting with the suspect drug:
Cefepime
Dosage: every 8:0,emperic therapy
Indication: Anaemia
Tretinoin
Dosage: continued until day 16,restarted from day 37 20mg/m2
Administration route: Oral
Cefepime
Dosage: every 8:0,emperic therapy
Indication: Thrombocytopenia
Fluconazole
Administration route: Oral
Cefepime
Dosage: every 8:0,emperic therapy
Indication: Febrile Neutropenia
Other drugs received by patient: Dipyrone TAB; Dipyrone TAB; Methotrexate; Dexamethasone; Dipyrone TAB
Possible Amphotericin B side effects in 47 year old female
Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-08
Patient: 47 year old female, weighing 68.8 kg (151.4 pounds)
Reactions: Tachycardia, Hypokalaemia, Weight Increased, Hepatomegaly, Bronchospasm, Thrombocytopenia, Renal Failure Acute, Dyspnoea, Pneumonia, Mouth Haemorrhage, Anaemia, Pulmonary Haemorrhage, Urethral Haemorrhage, Retinoic Acid Syndrome, Renal Impairment, Diarrhoea, Respiratory Failure, Oliguria, Asthenia, Leukopenia, Infusion Related Reaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Fluconazole
Dosage: 200 mg/day orally
Administration route: Oral
Indication: Candidiasis
Cytarabine
Dosage: 370 mg/m2/day ev, for 7 days
Cefepime
Dosage: 2 g every eight hours as empiric therapy, intravenous
Indication: Febrile Neutropenia
Dipyrone INJ
Dosage: 500 mg orally
Administration route: Oral
Indication: Febrile Neutropenia
ALL Transretinoic Acid (All Transretinoic Acid)
Dosage: 40 mg/m2/day orally, 20 mg/m2/day orally
Administration route: Oral
Indication: Chemotherapy
Amphotericin B
Dosage: 30 mg/day (6 hours of infusion), 240 mg (cumulative dose)
Indication: Candidiasis
Mitoxantrone
Dosage: 20 mg/m2/day ev, for 3 days
Indication: Chemotherapy
Meropenem
Dosage: 1 g ev, every eight hours
Possible Amphotericin B side effects in 47 year old female
Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-07
Patient: 47 year old female
Reactions: Dyspnoea, Hepatomegaly, Respiratory Tract Haemorrhage, Candidiasis, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Tretinoin
Dosage: unk
Administration route: Oral
Indication: Acute Promyelocytic Leukaemia
Mitoxantrone
Dosage: unk
Indication: Acute Promyelocytic Leukaemia
Fluconazole
Dosage: 200 mg/day
Administration route: Oral
Indication: Candidiasis
Metamizole
Dosage: unk
Indication: Acute Promyelocytic Leukaemia
Amphotericin B
Dosage: 30 mg/day 6:0
Indication: Product Used FOR Unknown Indication
Cefepime
Dosage: 2 g, every 8:0
Indication: Acute Promyelocytic Leukaemia
Cytarabine
Dosage: unk
Indication: Acute Promyelocytic Leukaemia
Other drugs received by patient: Meropenem; Methotrexate; Tretinoin
Possible Amphotericin B side effects in 47 year old male
Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-03
Patient: 47 year old male
Reactions: Respiratory Tract Haemorrhage, Mouth Ulceration, Pyrexia, Hypokalaemia, Weight Increased, Hepatomegaly, Proteinuria, Haemoglobinuria, Blood Creatinine Increased, Renal Failure Acute, Blood Urea Increased, Dyspnoea, Urine Output Decreased, Haematuria, Diarrhoea, Oral Disorder, Oliguria, Asthenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Amphotericin B
Dosage: 30 mg, qd
Fluconazole
Dosage: 200 mg, qd
Administration route: Oral
Cefepime
Dosage: 2 g, qd
Indication: Febrile Neutropenia
Tretinoin
Administration route: Oral
Other drugs received by patient: Dipyrone TAB; Mitoxantrone; Cytarabine; Meropenem; Dexamethasone
Possible Amphotericin B side effects in male
Reported by a individual with unspecified qualification from Korea, Republic of on 2012-02-27
Patient: male, weighing 55.0 kg (121.0 pounds)
Reactions: Pneumonia Fungal, Fatigue, Renal Failure Acute
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Voriconazole
Indication: Product Used FOR Unknown Indication
Xeloda
Dosage: date of most recent dose prior to sae: 31/jan/2012
Administration route: Oral
Indication: Gastric Cancer
Start date: 2011-12-21
Amphotericin B
Indication: Product Used FOR Unknown Indication
Pertuzumab
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Herceptin
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Cisplatin
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Possible Amphotericin B side effects in 34 year old female
Reported by a health professional (non-physician/pharmacist) from Brazil on 2011-11-18
Patient: 34 year old female, weighing 56.0 kg (123.2 pounds)
Reactions: Hyperpyrexia, Bronchopneumonia, Wheezing, Pyrexia, Multi-Organ Failure, Oral Candidiasis, Pulmonary Congestion, Cough, Renal Failure Acute, Oxygen Saturation Decreased, Dyspnoea, Metabolic Acidosis, Maternal Exposure During Pregnancy, Respiratory Distress, Cardiogenic Shock, Agranulocytosis, Fungal Infection, Oliguria, Systemic Inflammatory Response Syndrome, Neutropenia, Fusarium Infection, Septic Shock, Leukopenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nitrofurantoin
Indication: Infection Prophylaxis
Ganciclovir
Indication: Fusarium Infection
Nystatin
Administration route: Oral
Indication: Fusarium Infection
Amphotericin B
Ceftriaxone
Nystatin
Administration route: Oral
Metamizole Sodium
Indication: Tracheobronchitis
Ceftriaxone
Indication: Pyelonephritis
Ceftriaxone
Indication: Tracheobronchitis
Ceftriaxone
Clarithromycin
Indication: Fusarium Infection
Imipenem
Indication: Tracheobronchitis
Imipenem
Propranolol HCL
Indication: Mitral Valve Stenosis
Furosemide
Indication: Pulmonary Congestion
Nystatin
Administration route: Oral
Indication: Tracheobronchitis
Imipenem
Indication: Fusarium Infection
Ganciclovir
Vancomycin
Indication: Tracheobronchitis
Clarithromycin
Indication: Tracheobronchitis
Vancomycin
Clarithromycin
Ganciclovir
Indication: Tracheobronchitis
Vancomycin
Indication: Fusarium Infection
Amphotericin B
Indication: Tracheobronchitis
Amphotericin B
Indication: Fusarium Infection
Other drugs received by patient: Oxytocin; Dobutamine HCL; Vitamin TAB; Sodium Chloride; Nitric Oxide
Possible Amphotericin B side effects in 48 year old male
Reported by a physician from Germany on 2011-10-03
Patient: 48 year old male
Reactions: Overdose, Vomiting, Medication Error, Anaemia, Haemolysis, Renal Failure Acute
Drug(s) suspected as cause:
Amphotericin B
Indication: Cryptococcosis
Start date: 2011-08-13
Ambisome
Start date: 2011-08-08
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