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Amphotericin B (Amphotericin B) - Diarrhoea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Diarrhoea (7)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Amphotericin B where reactions include diarrhoea. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Amphotericin B side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-04-13

Patient: 47 year old male

Reactions: Respiratory Tract Haemorrhage, Mouth Ulceration, Pyrexia, Hypokalaemia, Weight Increased, Hepatomegaly, Proteinuria, Haemoglobinuria, Blood Creatinine Increased, Renal Failure Acute, Dyspnoea, Blood Urea Increased, Urine Output Decreased, Haematuria, Diarrhoea, Oral Disorder, Oliguria, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluconazole
    Dosage: 200 mg, qd
    Administration route: Oral

Tretinoin
    Administration route: Oral

Amphotericin B
    Dosage: 30 mg, qd

Cefepime
    Dosage: 2 g, qd
    Indication: Febrile Neutropenia

Other drugs received by patient: Meropenem; Mitoxantrone; Cytarabine; Dipyrone TAB; Dexamethasone



Possible Amphotericin B side effects in 47 year old female

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-09

Patient: 47 year old female, weighing 69.0 kg (151.8 pounds)

Reactions: Pneumonia Klebsiella, Hepatomegaly, Diarrhoea, Drug Interaction, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: for 7 days
    Administration route: Oral

Mitoxantrone
    Dosage: for 3 days
    Administration route: Oral

Amphotericin B
    Dosage: 6:0 on day13,stopped on day 21

Other drugs received by patient possibly interacting with the suspect drug:
Cefepime
    Dosage: every 8:0,emperic therapy
    Indication: Anaemia

Tretinoin
    Dosage: continued until day 16,restarted from day 37 20mg/m2
    Administration route: Oral

Cefepime
    Dosage: every 8:0,emperic therapy
    Indication: Thrombocytopenia

Fluconazole
    Administration route: Oral

Cefepime
    Dosage: every 8:0,emperic therapy
    Indication: Febrile Neutropenia

Other drugs received by patient: Dipyrone TAB; Dipyrone TAB; Methotrexate; Dexamethasone; Dipyrone TAB



Possible Amphotericin B side effects in 47 year old female

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-08

Patient: 47 year old female, weighing 68.8 kg (151.4 pounds)

Reactions: Tachycardia, Hypokalaemia, Weight Increased, Hepatomegaly, Bronchospasm, Thrombocytopenia, Renal Failure Acute, Dyspnoea, Pneumonia, Mouth Haemorrhage, Anaemia, Pulmonary Haemorrhage, Urethral Haemorrhage, Retinoic Acid Syndrome, Renal Impairment, Diarrhoea, Respiratory Failure, Oliguria, Asthenia, Leukopenia, Infusion Related Reaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluconazole
    Dosage: 200 mg/day orally
    Administration route: Oral
    Indication: Candidiasis

Cytarabine
    Dosage: 370 mg/m2/day ev, for 7 days

Cefepime
    Dosage: 2 g every eight hours as empiric therapy, intravenous
    Indication: Febrile Neutropenia

Dipyrone INJ
    Dosage: 500 mg orally
    Administration route: Oral
    Indication: Febrile Neutropenia

ALL Transretinoic Acid (All Transretinoic Acid)
    Dosage: 40 mg/m2/day orally, 20 mg/m2/day orally
    Administration route: Oral
    Indication: Chemotherapy

Amphotericin B
    Dosage: 30 mg/day (6 hours of infusion), 240 mg (cumulative dose)
    Indication: Candidiasis

Mitoxantrone
    Dosage: 20 mg/m2/day ev, for 3 days
    Indication: Chemotherapy

Meropenem
    Dosage: 1 g ev, every eight hours



Possible Amphotericin B side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-03-03

Patient: 47 year old male

Reactions: Respiratory Tract Haemorrhage, Mouth Ulceration, Pyrexia, Hypokalaemia, Weight Increased, Hepatomegaly, Proteinuria, Haemoglobinuria, Blood Creatinine Increased, Renal Failure Acute, Blood Urea Increased, Dyspnoea, Urine Output Decreased, Haematuria, Diarrhoea, Oral Disorder, Oliguria, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amphotericin B
    Dosage: 30 mg, qd

Fluconazole
    Dosage: 200 mg, qd
    Administration route: Oral

Cefepime
    Dosage: 2 g, qd
    Indication: Febrile Neutropenia

Tretinoin
    Administration route: Oral

Other drugs received by patient: Dipyrone TAB; Mitoxantrone; Cytarabine; Meropenem; Dexamethasone



Possible Amphotericin B side effects in 16 year old male

Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-01-24

Patient: 16 year old male

Reactions: Swelling Face, Pyrexia, Transaminases Increased, Serum Sickness-Like Reaction, Diarrhoea, Oedema Peripheral, Rash Erythematous, Thrombocytopenia, Rash Maculo-Papular

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vancomycin

Amikacin
    Dosage: 15 mg/kg, qd
    Indication: Febrile Neutropenia

Immune Globulin (Human)

Meropenem

Amphotericin B

Other drugs received by patient: Ceftazidime



Possible Amphotericin B side effects in female

Reported by a pharmacist from United States on 2011-12-16

Patient: female, weighing 61.2 kg (134.7 pounds)

Reactions: Vomiting, Diarrhoea, Nausea

Drug(s) suspected as cause:
Amphotericin B



Possible Amphotericin B side effects in 75 year old female

Reported by a individual with unspecified qualification from Japan on 2011-11-11

Patient: 75 year old female

Reactions: Renal Tubular Disorder, Blood Urea Increased, Alanine Aminotransferase Increased, Urticaria, Hypokalaemia, Haematochezia, Haemoglobin Decreased, Diarrhoea, Gamma-Glutamyltransferase Increased, Aspartate Aminotransferase Increased, Colitis, Platelet Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Flucytosine
    Administration route: Oral
    Start date: 2011-08-09
    End date: 2011-09-06

Flucytosine
    Administration route: Oral
    Start date: 2011-08-09
    End date: 2011-09-06

Amphotericin B
    Indication: Meningitis Cryptococcal
    Start date: 2011-08-08
    End date: 2011-09-01

Flucytosine
    Administration route: Oral
    Start date: 2011-08-09
    End date: 2011-09-06

Amphotericin B
    Start date: 2011-08-08
    End date: 2011-09-01

Amphotericin B
    Start date: 2011-09-02
    End date: 2011-09-05

Amphotericin B
    Start date: 2011-09-06
    End date: 2011-09-06

Flucytosine
    Administration route: Oral
    Indication: Meningitis Cryptococcal
    Start date: 2011-08-09
    End date: 2011-09-06

Amphotericin B
    Start date: 2011-09-02
    End date: 2011-09-05

Amphotericin B
    Start date: 2011-09-06
    End date: 2011-09-06

Other drugs received by patient: Lansoprazole; Urso 250; Prednisolone; Livact; Vitamedin

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