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Alprazolam (Alprazolam) - Renal Failure - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Renal Failure ()

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Alprazolam where reactions include renal failure. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Alprazolam side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient:

Reactions: Agitation, Pneumonia, Pain in Extremity, Hypotension, Hemiparesis, Cognitive Disorder, Delirium, Renal Failure, Hallucination, Visual, Arthralgia, Sepsis, Blood Culture Positive, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amitriptyline HCL
    Dosage: 100 mg, unk

Levothyroxine Sodium
    Dosage: 150 mg, unk

Hydromorphine Hydrochloride
    Dosage: 20 mg, bid
    Administration route: Oral

Zocor
    Dosage: 40 mg, unk
    Administration route: Oral

Diazepam
    Dosage: 5 mg, bid

Fluoxetine HCL
    Dosage: 40 mg, unk
    Administration route: Oral

Alprazolam
    Dosage: 0.5 mg, unk

Lorazepam
    Dosage: 2 mg, every few hours
    Administration route: Oral

Gabapentin
    Dosage: 900 mg, over 3 days up to 900mg per day

Other drugs received by patient: Metoprolol Tartrate; Aspirin; Fentanyl Citrate; Anastrozole; Dipyrone Magnesium; Nitroglycerin; Polyethylene Glycol



Possible Alprazolam side effects in 62 year old female

Reported by a consumer/non-health professional from Israel on 2012-06-04

Patient: 62 year old female

Reactions: Renal Failure, Sepsis, Hemiparesis, Delirium

Drug(s) suspected as cause:
Gabapentin
    Dosage: up to 900 mg/day
    Indication: Neuralgia

Quetiapine
    Dosage: 25 mg, unk
    Administration route: Oral
    Indication: Delirium

Hydromorphone HCL
    Dosage: 5.2 mg
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Alprazolam
    Dosage: 0.5 mg/day
    Indication: Depression

Amitriptyline HCL
    Dosage: 100 mg/day
    Indication: Depression

Fentanyl-100
    Dosage: 75 ug in 72 hours
    Indication: Product Used FOR Unknown Indication

Fluoxetine
    Dosage: 40 mg/day
    Indication: Depression

Fentanyl-100
    Dosage: 150 ug

Hydromorphone HCL
    Dosage: 20 mg, bid

Diazepam
    Dosage: 5 mg, bid
    Indication: Depression

Quetiapine
    Dosage: 100 mg, unk

Other drugs received by patient: Nitroglycerin; Clindamycin / Levofloxacin; Simvastatin; Levothyroxine Sodium; Aspirin; Dipyrone TAB; Metamizol; Metoprolol Tartrate; Aminopenicillin / Clavuclanacid; Anastrozole; Polyethylene Glycol



Possible Alprazolam side effects in 62 year old female

Reported by a health professional (non-physician/pharmacist) from Israel on 2012-05-29

Patient: 62 year old female

Reactions: Renal Failure, Sepsis, Hemiparesis, Delirium

Drug(s) suspected as cause:
Amitriptyline HCL
    Dosage: 100 mg/day
    Indication: Depression

Quetiapine
    Dosage: unk
    Indication: Delirium

Fentanyl-100
    Dosage: 150 ug

Diazepam
    Dosage: 5 mg, bid
    Indication: Depression

Hydromorphone HCL
    Dosage: 5.2 mg
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Fluoxetine
    Dosage: 40 mg/day
    Indication: Depression

Alprazolam
    Dosage: 0.5 mg/day
    Indication: Depression

Fentanyl-100
    Dosage: 75 ug in 72 hours
    Indication: Product Used FOR Unknown Indication

Gabapentin
    Dosage: up to 900 mg/day
    Indication: Neuralgia

Other drugs received by patient: Levothyroxine Sodium; Nitroglycerin; Metoprolol Tartrate; Simvastatin; Anastrozole; Dipyrone TAB; Aspirin



Possible Alprazolam side effects in 36 year old female

Reported by a physician from Taiwan, Province of China on 2012-05-25

Patient: 36 year old female

Reactions: Disseminated Intravascular Coagulation, Coma, Muscle Rigidity, Hyperhidrosis, Ecchymosis, Circulatory Collapse, Mouth Haemorrhage, Hypotension, General Physical Health Deterioration, Toxicity To Various Agents, Tremor, Electrocardiogram QT Prolonged, Rhabdomyolysis, Hyperthermia, Ventricular Arrhythmia, Intentional Drug Misuse, Extensor Plantar Response, Shift To THE Left, Electrocardiogram QRS Complex Prolonged, Thrombocytopenia, Oxygen Saturation Decreased, Blood Glucose Increased, Hypertonia, Mydriasis, Hyperreflexia, Muscle Twitching, Renal Failure, Respiratory Failure, Bradycardia, Sinus Tachycardia, Blood Pressure Decreased, Leukocytosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Moclobemide (Moclobemide)
    Dosage: 4500 mg;1x

Alprazolam
    Dosage: 15 mg;1x

Lorazepam
    Dosage: 10 mg;1x

Estazolam
    Dosage: 20 mg;1x

Midazolam HCL
    Dosage: 75 mg;1x

Bromazepam (Bromazepam)
    Dosage: 60 mg;1x

Fluoxetine Hydrochloride
    Dosage: 200 mg;1x

Alprazolam
    Dosage: 300 mg;1x



Possible Alprazolam side effects in

Reported by a physician from Austria on 2012-05-24

Patient:

Reactions: Renal Failure, Pneumonia, Hemiparesis, Delirium, Staphylococcal Sepsis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gabapentin
    Dosage: 900 mg, / day (over 3 days)
    Indication: Bone Pain

Fentanyl-100
    Dosage: 75 mcg, in 72 hours
    Indication: Product Used FOR Unknown Indication

Alprazolam
    Dosage: 0.5 mg, / day
    Indication: Product Used FOR Unknown Indication

Diazepam
    Dosage: 2 df, / day
    Indication: Product Used FOR Unknown Indication

Amitriptyline HCL
    Dosage: 100 mg, / day
    Indication: Product Used FOR Unknown Indication

Fentanyl-100
    Dosage: 150 mcg, in 72 hours

Fluoxetine HCL
    Dosage: 40 mg, / day
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Hydromorphone HCL; Levothyroxine Sodium; Aspirin; Simvastatin; Hydromorphone HCL; Anastrozole; Metoprolol; Nitroglycerin; Polyethylene Glycol; Metamizol



Possible Alprazolam side effects in 62 year old female

Reported by a health professional (non-physician/pharmacist) from Austria on 2012-05-18

Patient: 62 year old female

Reactions: Renal Failure, Sepsis, Hemiparesis, Delirium

Drug(s) suspected as cause:
Fluoxetine
    Dosage: 40 mg/day
    Indication: Depression

Fentanyl-100
    Dosage: 150 ug

Hydromorphone HCL
    Dosage: 5.2 mg
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Gabapentin
    Dosage: up to 900 mg/day
    Indication: Neuralgia

Quetiapine
    Dosage: unk
    Indication: Delirium

Fentanyl-100
    Dosage: 75 ug in 72 hours
    Indication: Product Used FOR Unknown Indication

Diazepam
    Dosage: 5 mg, bid
    Indication: Depression

Alprazolam
    Dosage: 0.5 mg/day
    Indication: Depression

Amitriptyline HCL
    Dosage: 100 mg/day
    Indication: Depression

Other drugs received by patient: Haloperidol; Lorazepam; Midazolam



Possible Alprazolam side effects in 62 year old female

Reported by a physician from Austria on 2012-05-17

Patient: 62 year old female

Reactions: Renal Failure, Sepsis, Delirium

Drug(s) suspected as cause:
Fluoxetine
    Dosage: 40 mg/day

Diazepam
    Dosage: 2 x 5mg

Fentanyl-100

Fentanyl-100
    Dosage: 150 microg

Amitriptyline HCL
    Dosage: 100 mg/day

Alprazolam
    Dosage: 0.5 mg/day

Hydromorphone HCL
    Dosage: 5.2mg (rescue medication)
    Administration route: Oral
    Start date: 2010-01-01

Gabapentin
    Dosage: over 3 days up to 900 mg/day
    Indication: Neuralgia
    Start date: 2010-01-01

Other drugs received by patient: Nitroglycerin; Levothyroxine Sodium; Metoprolol; Aspirin; Simvastatin; Anastrozole; Dipyrone TAB



Possible Alprazolam side effects in 62 year old female

Reported by a health professional (non-physician/pharmacist) from Austria on 2012-05-09

Patient: 62 year old female

Reactions: Confusional State, Agitation, Pneumonia, Hypotension, Cognitive Disorder, Hemiparesis, Delirium, Renal Failure, Staphylococcal Infection, Sepsis, Thrombocytopenia, Hallucination

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Diazepam
    Dosage: 2-5 mg daily

Amitriptyline HCL
    Dosage: 100 mg daily

Hydromorphone HCL
    Dosage: 5.2 mg per day
    Indication: Bone Pain

Fluoxetine
    Dosage: 40 mg daily

Hydromorphone HCL
    Dosage: 20 mg, bid

Alprazolam
    Dosage: 0.5 mg daily

Gabapentin
    Dosage: 900 mg per day
    Indication: Bone Pain

Other drugs received by patient: Fentanyl; Simvastatin; Metamizole; Metoprolol Tartrate; Anastrozole; Levothyroxine Sodium; Acetylsalicylic Acid SRT; Fentanyl; Nitrglycerin Transdermal System; Polyethylene Glycol



Possible Alprazolam side effects in 62 year old female

Reported by a health professional (non-physician/pharmacist) from Austria on 2012-04-09

Patient: 62 year old female

Reactions: Agitation, Pneumonia, Pain in Extremity, Hypotension, Hemiparesis, Cognitive Disorder, Delirium, Renal Failure, Arthralgia, Hallucination, Visual, Blood Culture Positive, Sepsis, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Levothyroxine Sodium
    Dosage: (150 mcg, 1 d)
    Indication: Product Used FOR Unknown Indication

Hydromorphone HCL
    Dosage: (5.2 mg) 40 mg (20 mg, 2 in 1 d)
    Administration route: Oral
    Indication: Bone Pain
    Start date: 2010-09-01

Fluoxetine Hydrochloride
    Dosage: (40 mg)
    Indication: Product Used FOR Unknown Indication

Gabapentin
    Dosage: (900 mg, over 3 days up to 900mg per day)
    Indication: Bone Pain
    Start date: 2010-09-01

Amitriptyline Hydrochloride
    Dosage: (100 mg)
    Indication: Product Used FOR Unknown Indication

Alprazolam
    Dosage: (0.5 mg)
    Indication: Product Used FOR Unknown Indication

Diazepam
    Dosage: 10 mg (5 mg, 2 in 1 d)
    Indication: Product Used FOR Unknown Indication

Lorazepam
    Dosage: (2 mg, every few hours) (2 mg, 1 d)
    Indication: Delirium

Simvastatin
    Dosage: (40 mg)
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Acetylsalicylic Acid SRT; Fentanyl; Macrogol (Macrogol); Metamizol (Metamizole Magnesium); Nitroglycerine (Nitroglycerin) (Glyceryl Trinitrate); Anastrozol (Anastrozole) (Anastrozole); Metoprolol Tartrate



Possible Alprazolam side effects in 36 year old female

Reported by a physician from Taiwan, Province of China on 2012-04-02

Patient: 36 year old female

Reactions: Electrocardiogram QT Prolonged, Disseminated Intravascular Coagulation, Ventricular Arrhythmia, Coma, Serotonin Syndrome, Shift To THE Left, Electrocardiogram QRS Complex Prolonged, Multiple Drug Overdose Intentional, Circulatory Collapse, Blood Creatinine Increased, Thrombocytopenia, Blood Glucose Increased, Antidepressant Drug Level Below Therapeutic, Renal Failure, Respiratory Failure, Bradycardia, Sinus Tachycardia, Blood Pressure Decreased

Adverse event resulted in: death

Drug(s) suspected as cause:
Lorazepam
    Dosage: 1 mg

Lorazepam
    Dosage: 10 mg

Fluoxetine
    Dosage: 20 mg

Estazolam
    Dosage: 20 mg

Midazolam
    Dosage: 7.5 mg

Fluoxetine
    Dosage: 200 mg

Estazolam
    Dosage: 2 mg

Midazolam
    Dosage: 75 mg

Bromazepam
    Dosage: 60 mg

Alprazolam
    Dosage: 1.5 mg

Moclobemide
    Dosage: 4500 mg

Propranolol
    Dosage: 30 mg

Propranolol
    Dosage: 300 mg

Moclobemide
    Dosage: 450 mg

Alprazolam
    Dosage: 15 mg

Bromazepam
    Dosage: 6 mg



Possible Alprazolam side effects in 70 year old female

Reported by a consumer/non-health professional from United States on 2012-03-30

Patient: 70 year old female

Reactions: Renal Failure, Depression, Transient Ischaemic Attack

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Metoprolol Tartrate
    Administration route: Oral
    Start date: 2009-02-03

Trazodone HCL
    Dosage: 2tabs at bedtime as necessary
    Administration route: Oral
    Indication: Insomnia
    Start date: 2004-08-30

Metformin HCL
    Administration route: Oral
    Start date: 2009-12-08

Alprazolam
    Dosage: tab
    Administration route: Oral
    Start date: 2004-08-30

Ciprofloxacin

Lyrica
    Administration route: Oral
    Indication: Neuropathy Peripheral
    Start date: 2009-07-30

Other drugs received by patient: Furosemide; Klor-CON M; Lyrica; Tricor; Amitriptyline HCL; Carafate; Omeprazole; Promethazine HCL; Tizanidine HCL; Albuterol Sulfate; Fluticasone Propionate; Glyburide



Possible Alprazolam side effects in 36 year old female

Reported by a physician from Taiwan, Province of China on 2012-03-26

Patient: 36 year old female

Reactions: Unresponsive To Stimuli, Disseminated Intravascular Coagulation, Coma, Serotonin Syndrome, Muscle Rigidity, Hyperhidrosis, Ecchymosis, Circulatory Collapse, Pupillary Reflex Impaired, Respiratory Rate Increased, Mouth Haemorrhage, Hypotension, Tremor, Antidepressant Drug Level Below Therapeutic, Electrocardiogram QT Prolonged, Rhabdomyolysis, Hyperthermia, Chills, Blood PH Decreased, Ventricular Arrhythmia, Extensor Plantar Response, PO2 Decreased, Shift To THE Left, Electrocardiogram QRS Complex Prolonged, Completed Suicide, Multiple Drug Overdose Intentional, Blood Glucose Increased, Hypertonia, Oxygen Saturation Decreased, Mydriasis, Hyperreflexia, Muscle Twitching, Renal Failure, Bradycardia, Sinus Tachycardia, Leukocytosis

Adverse event resulted in: death

Drug(s) suspected as cause:
Alprazolam
    Dosage: 15 mg, 1 x not the prescribed amount) (2 mg, qd, at bedtime)
    Indication: Product Used FOR Unknown Indication

Midazolam HCL
    Dosage: 75 mg, 1 x not the prescribed amount) (6 mg, at bedtime)
    Indication: Product Used FOR Unknown Indication

Bromazepam (Bromazepam)
    Dosage: 60 mg 1x, not the prescribed amount), (5 mg, qd, a bedtime)
    Indication: Product Used FOR Unknown Indication

Lorazepam
    Dosage: 10 mg, 1x, not the prescribed amount), (1 mg, qd at bedtime)
    Indication: Product Used FOR Unknown Indication

Moclobemide (Moclobemide)
    Dosage: 4500 mg 1x, not the presribed amount, (150 mg, tid)
    Indication: Product Used FOR Unknown Indication

Propranolol
    Dosage: 300 mg, 1 x not the prescribed amount, (10 mg, tid)
    Indication: Product Used FOR Unknown Indication

Estazolam
    Dosage: 20 mg, 1 x, not the prescribed amount (2 mg, qd, at bedtime)
    Indication: Product Used FOR Unknown Indication

Midazolam HCL
    Dosage: 75 mg 1x, not the prescribed amount, 7.5 mg qd, at bedtime
    Indication: Product Used FOR Unknown Indication

Fluoxetine
    Dosage: 200 mg, 1 x not the prescribed amount), (20 mg, qd)
    Indication: Product Used FOR Unknown Indication



Possible Alprazolam side effects in 62 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-03-20

Patient: 62 year old male

Reactions: Renal Failure, Diarrhoea, Urinary Incontinence, Hyponatraemia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Effexor XR
    Dosage: 75 mg, 3x/day
    Administration route: Oral
    End date: 2011-12-24

Felodipine
    Dosage: 1 dosage form, 1x/day
    Administration route: Oral
    End date: 2011-12-24

Mirtazapine
    Dosage: 15 mg, 2x/day
    Administration route: Oral
    End date: 2011-12-24

Irbesartan + Hydrochlorothiazide
    Dosage: 1 dosage form, 1x/day
    Administration route: Oral
    End date: 2011-12-24

Alprazolam
    Dosage: 0.125 mg in the morning and 0.25 mg in the evening
    Administration route: Oral
    End date: 2011-12-24

Other drugs received by patient: Imovane



Possible Alprazolam side effects in 62 year old female

Reported by a health professional (non-physician/pharmacist) on 2012-03-20

Patient: 62 year old female

Reactions: Renal Failure, Pneumonia, Sepsis, Delirium

Drug(s) suspected as cause:
Metoprolol Tartrate
    Dosage: (47.5 mg, 1 d)
    Indication: Product Used FOR Unknown Indication

Simvastatin
    Dosage: (40 mg, 1 d)
    Indication: Product Used FOR Unknown Indication

Fentanyl
    Dosage: (75 mcg, 72 hr), transdermal
    Indication: Product Used FOR Unknown Indication

Anastrozole
    Dosage: (1 d)
    Indication: Hormone Therapy

Macrogol (Macrogol)
    Dosage: (1 d)
    Indication: Product Used FOR Unknown Indication

Amitriptyline HCL
    Dosage: (100 mg, 1 d)
    Indication: Product Used FOR Unknown Indication

Aspirin
    Dosage: (100 mg, 1 d)
    Indication: Product Used FOR Unknown Indication

Gabapentin
    Dosage: (900 mg, 1 d)
    Indication: Bone Pain

Metamizole (Metamizole)
    Dosage: (4 gm, 1 d)
    Indication: Product Used FOR Unknown Indication

Nitroglycerin
    Dosage: (1 d), transdermal
    Indication: Product Used FOR Unknown Indication

Alprazolam
    Dosage: (0.5 mg, 1 d)
    Indication: Product Used FOR Unknown Indication

Fluoxetine
    Dosage: (40 mg, 1 d)
    Indication: Product Used FOR Unknown Indication

Hydromorphone HCL
    Dosage: (5.2 mg), oral
    Administration route: Oral
    Indication: Bone Pain

Levothyroxine Sodium
    Dosage: (150 mcg, 1 d)
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Diazepam; Bisphosphonate (Bisphosphonates); Fulvestrant (Fulvestrant); Exemestane; Doxorubicin HCL



Possible Alprazolam side effects in 62 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-03-16

Patient: 62 year old male

Reactions: Confusional State, Hypochloraemia, Urinary Incontinence, Iatrogenic Injury, General Physical Health Deterioration, Conduction Disorder, Hyponatraemia, Fall, Hypokalaemia, Renal Failure, Diarrhoea, Gait Disturbance, Electrocardiogram Repolarisation Abnormality, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Irbesartan and Hydrochlorothiazide
    Dosage: 1 df; qd; po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2011-12-24

Effexor
    Dosage: 75 mg; tid; po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2011-12-24

Alprazolam
    Dosage: 0.375 mg; qd; po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2011-12-24

Logimax (Modiloc)
    Dosage: 1 df; qd
    Indication: Product Used FOR Unknown Indication
    End date: 2011-12-24

Mirtazapine
    Dosage: 15 mg; bid; po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2011-12-24

Other drugs received by patient: Imovane



Possible Alprazolam side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from Taiwan, Province of China on 2012-01-20

Patient: 36 year old female

Reactions: Electrocardiogram QT Prolonged, Rhabdomyolysis, Intentional Overdose, Unresponsive To Stimuli, Disseminated Intravascular Coagulation, Chills, Blood PH Decreased, Ventricular Arrhythmia, Coma, Serotonin Syndrome, Hyperhidrosis, Muscle Rigidity, Electrocardiogram QRS Complex Prolonged, Completed Suicide, Multiple Drug Overdose Intentional, Circulatory Collapse, Blood Glucose Increased, Pupillary Reflex Impaired, Respiratory Rate Increased, Mydriasis, Hypotension, Muscle Twitching, Convulsion, Tremor, Renal Failure, Respiratory Failure, Nervous System Disorder, Bradycardia, Leukocytosis, Sinus Tachycardia

Adverse event resulted in: death

Drug(s) suspected as cause:
Alprazolam
    Dosage: 15 mg

Lorazepam
    Dosage: 10 mg

Estazolam
    Dosage: 2 mg, 1x/day

Moclobemide
    Dosage: 150 mg, 3x/day

Estazolam
    Dosage: 20 mg

Bromazepam
    Dosage: 6 mg, 1x/day

Midazolam
    Dosage: 7.5 mg, at bedtime

Propranolol HCL
    Dosage: 10 mg, 3x/day

Propranolol HCL
    Dosage: 300 mg

Moclobemide
    Dosage: 4,500 mg

Fluoxetine
    Dosage: 20 mg, 1x/day

Alprazolam
    Dosage: 0.5 mg, 3x/day

Lorazepam
    Dosage: 1 mg, 1x/day

Fluoxetine
    Dosage: 200 mg

Bromazepam
    Dosage: 60 mg

Midazolam
    Dosage: 75 mg

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