Alimta (Pemetrexed) - Hospitalization - Suspected Cause - Side Effect Reports

Possible Alimta side effects in male

Reported by a consumer/non-health professional from Japan on 2012-08-27

Patient: male, weighing 80.0 kg (176.0 pounds)

Reactions: Off Label Use, White Blood Cell Count Decreased, Neoplasm Progression, Metastases To Bone, Nephrotic Syndrome, Acute Prerenal Failure

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 750 mg, every 3 weeks
    Indication: Pleural Mesothelioma Malignant
    Start date: 2009-03-12
    End date: 2009-09-24

Gemzar
    Dosage: unk
    Start date: 2010-05-28
    End date: 2010-06-04

Other drugs received by patient: Amlodipine; Vitamin B12; Panvitan; Calblock; Amlodipine; Cisplatin

Possible Alimta side effects in female

Reported by a physician from Italy on 2012-08-24

Patient: female

Reactions: Lung Disorder, Haemorrhage, Anaemia, Petechiae, Neoplasm Progression, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Folic Acid; Dexamethasone Sodium Phosphate; Dobetin; Benzodiazepine Related Drugs

Possible Alimta side effects in male

Reported by a consumer/non-health professional from Netherlands on 2012-08-23

Patient: male

Reactions: Pulmonary Toxicity, Death

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Omeprazole; Cisplatin; Hydroxocobalamine; Folic Acid

Possible Alimta side effects in 58 year old female

Reported by a consumer/non-health professional from Brazil on 2012-08-16

Patient: 58 year old female

Reactions: Abdominal Pain, Toxicity To Various Agents

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Carboplatin

Possible Alimta side effects in male

Reported by a physician from Japan on 2012-08-15

Patient: male, weighing 61.7 kg (135.7 pounds)

Reactions: C-Reactive Protein Increased, Platelet Count Decreased, Pyrexia, Loss of Consciousness, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Vitamin B12; Panvitan

Possible Alimta side effects in 70 year old male

Reported by a consumer/non-health professional from Japan on 2012-08-15

Patient: 70 year old male

Reactions: Hypersensitivity, C-Reactive Protein Increased, Pyrexia, Neutrophil Count Decreased, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Vitamin B-12; Folic Acid

Possible Alimta side effects in female

Reported by a physician from France on 2012-08-15

Patient: female

Reactions: Dyspnoea, Nausea, Rash, Hyperhidrosis, Syncope, Epigastric Discomfort, Rash Erythematous, Conjunctival Hyperaemia, Bronchospasm

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: B12-Vitamiin; Methylprednisolone; Polaramine; Avastin; Pravastatin; Acetaminophen; Zofran; Folic Acid; Enalapril Maleate

Possible Alimta side effects in female

Reported by a consumer/non-health professional from Belgium on 2012-08-15

Patient: female, weighing 64.0 kg (140.8 pounds)

Reactions: Death, Off Label Use, Dyspnoea Exertional, Interstitial Lung Disease

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 500 mg/m2, unknown

Alimta
    Dosage: 500 mg/m2, unknown
    Indication: Thymoma Malignant
    Start date: 2012-01-31

Other drugs received by patient: Dexamethasone; Bisoprolol Fumarate; Vitamin B-12; Folic Acid

Possible Alimta side effects in male

Reported by a physician from France on 2012-08-13

Patient: male

Reactions: Carcinoembryonic Antigen Increased, Anaemia, Thrombocytopenia, Streptococcal Infection, Renal Failure Chronic

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Possible Alimta side effects in 65 year old male

Reported by a consumer/non-health professional from United States on 2012-08-13

Patient: 65 year old male, weighing 67.0 kg (147.4 pounds)

Reactions: Weight Decreased, Mucosal Inflammation, Vomiting

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: last dose on 9jul12,375mg/m2
    Indication: non-Small Cell Lung Cancer Stage III
    Start date: 2012-05-21

Cisplatin
    Dosage: last dose on 9jul12,50mg/m2
    Indication: non-Small Cell Lung Cancer Stage III
    Start date: 2012-05-21

Other drugs received by patient: Dexamethasone; Kytril; Antepsin; Isosorbide Dinitrate; Folic Acid; Vitamin B-12

Possible Alimta side effects in male

Reported by a consumer/non-health professional from Italy on 2012-08-13

Patient: male

Reactions: Diarrhoea, Hypotension, Depressed Level of Consciousness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Carboplatin

Possible Alimta side effects in male

Reported by a consumer/non-health professional from Netherlands on 2012-08-10

Patient: male

Reactions: Pulmonary Toxicity

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Folic Acid; Cisplatin; Hydroxocobalamine; Omeprazole

Possible Alimta side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-10

Patient: male, weighing 92.0 kg (202.4 pounds)

Reactions: Mental Disorder, Gait Disturbance

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 500 mg/m2, every 21 days
    Indication: Lung Cancer Metastatic
    Start date: 2011-07-20
    End date: 2011-07-27

Gemzar
    Dosage: 1000 mg/m2, unk
    Indication: Lung Cancer Metastatic

Possible Alimta side effects in male

Reported by a physician from France on 2012-08-09

Patient: male

Reactions: Xerosis, Oedema Peripheral, Rash, Asthenia, Erysipelas

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Dexeryl; Leucovorin Calcium; Carboplatin; Bepanthene; Lercanidipine; Vitamin B-12; Amlodipine

Possible Alimta side effects in male

Reported by a consumer/non-health professional from France on 2012-08-09

Patient: male

Reactions: Osteonecrosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Atorvastatin; Diprosone; Oxycontin; Carboplatin; Zometa; Polyethylene Glycol; Eprex; Metoprolol Tartrate; Aspirin; Pantoprazole; Atarax

Possible Alimta side effects in male

Reported by a physician from France on 2012-08-09

Patient: male

Reactions: Dyspnoea, Haemolytic Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Folic Acid; Emend; Vitamin B-12; Lyrica; Oxycontin; Ondansetron; Cisplatin; Oxycodone Hydrochloride; Dexamethasone; Zometa; Methylprednisolone

Possible Alimta side effects in female

Reported by a physician from France on 2012-08-09

Patient: female

Reactions: Hot Flush, Vomiting, Chills, Hypotension, Convulsion, Oxygen Saturation Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Carboplatin

Possible Alimta side effects in male

Reported by a physician from Japan on 2012-08-08

Patient: male, weighing 57.0 kg (125.4 pounds)

Reactions: Interstitial Lung Disease, Neoplasm Progression

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 500 mg/m2, q21d
    Indication: non-Small Cell Lung Cancer Stage Iiib
    Start date: 2012-07-10
    End date: 2012-07-10

Gemzar
    Dosage: unk
    Indication: non-Small Cell Lung Cancer Stage Iiib
    Start date: 2012-02-21
    End date: 2012-06-05

Other drugs received by patient: Januvia; Lyrica; Alinamin F; Carnaculin / 00088101 /; Prednisolone; Sennoside / 00571901 /; Glimepiride; Procaterol HCL; Coldrin; Vitamin B12; Vitamin B12; Mucodyne; Folic Acid; Carboplatin; Methycool

Possible Alimta side effects in

Reported by a consumer/non-health professional from Italy on 2012-08-08

Patient:

Reactions: Diarrhoea, Hypotension, Akinaesthesia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Carboplatin

Possible Alimta side effects in female

Reported by a consumer/non-health professional from France on 2012-08-06

Patient: female

Reactions: Death, Neoplasm Progression, Aplasia, Septic Shock

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 765 mg, unk
    Indication: Adenocarcinoma
    Start date: 2012-06-13

Gemzar
    Dosage: unk
    Start date: 2010-03-17
    End date: 2012-04-10

Other drugs received by patient: Cisplatin; Solu-Medrol; Zofran; Tarceva; Neulasta; Carboplatin; Emend; Emend

Possible Alimta side effects in 55 year old female

Reported by a physician from Germany on 2012-08-06

Patient: 55 year old female

Reactions: Stomatitis, Mouth Haemorrhage, Alanine Aminotransferase Increased, Anaemia, Paraneoplastic Syndrome, Febrile Neutropenia, Diarrhoea, Aspartate Aminotransferase Increased, Granulocytopenia, Autoimmune Thrombocytopenia, Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Prednisone TAB; Dexamethasone Sodium Phosphate; Ranitidine; Allopurinol; Opioids; Cisplatin; Novalgin; Aprepitant; Folic Acid; Ondansetron; Vitamin B-12

Possible Alimta side effects in 55 year old male

Reported by a consumer/non-health professional from Japan on 2012-08-06

Patient: 55 year old male

Reactions: Pulmonary Artery Thrombosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Carboplatin; Panvitan / 00466101 /; Vitamin B-12

Possible Alimta side effects in 59 year old male

Reported by a physician from Netherlands on 2012-08-06

Patient: 59 year old male

Reactions: Pulmonary Toxicity

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: unk
    Indication: Mesothelioma Malignant
    Start date: 2012-06-25

Cisplatin
    Dosage: unk mg/ml, unk
    Indication: Mesothelioma Malignant
    Start date: 2012-06-25

Other drugs received by patient: Omeprazole; Hydroxocobalamin; Folic Acid

Possible Alimta side effects in female

Reported by a consumer/non-health professional from Japan on 2012-08-03

Patient: female, weighing 57.0 kg (125.4 pounds)

Reactions: Large Intestine Perforation, Pneumonia, Disseminated Intravascular Coagulation, Rash, Peritonitis, Liver Disorder, Haemoglobin Decreased, Malaise, Respiratory Failure, Enterocolitis, Decreased Appetite, Shock, Candidiasis

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 700 mg/m2, unk
    Start date: 2010-11-16
    End date: 2010-12-14

Alimta
    Dosage: 700 mg/m2, unk
    Indication: Large Cell Lung Cancer Stage III
    Start date: 2010-07-20
    End date: 2010-10-13

Alimta
    Dosage: 700 mg/m2, unk
    Start date: 2012-01-18
    End date: 2012-02-14

Other drugs received by patient: Gascon; Vitamin B12; Norvasc; Magmitt; Folic Acid; Vitamin B12; Levothyroxine Sodium; Vitamin B12; Selbex; Cisplatin; Aspirin; Vitamin B12; Vinorelbine; Folic Acid

Possible Alimta side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-03

Patient: female

Reactions: Hypersensitivity, Vomiting, Hypotension, Chills, Urinary Incontinence, Postictal State, Convulsion, Hot Flush, Injection Related Reaction, Metastases To Central Nervous System

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Indication: Small Cell Lung Cancer Extensive Stage
    Start date: 2012-05-29
    End date: 2012-07-10

Carboplatin
    Indication: Small Cell Lung Cancer Extensive Stage
    Start date: 2012-05-29
    End date: 2012-07-10

Possible Alimta side effects in 75 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-03

Patient: 75 year old female

Reactions: Death, Creatinine Renal Clearance Abnormal, Septic Shock, Aplasia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 765 mg, unknown/d
    Indication: Adenocarcinoma
    Start date: 2012-06-13
    End date: 2012-06-13

Carboplatin
    Dosage: 279 mg, unknown/d
    Indication: Adenocarcinoma
    Start date: 2012-06-13
    End date: 2012-06-13

Tarceva
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Indication: Adenocarcinoma
    Start date: 2010-07-23
    End date: 2012-06-24

Other drugs received by patient: Emend; Gemzar; Emend; Neulasta; Solu-Medrol; Zophren / 00955302 /; Cisplatin

Possible Alimta side effects in female

Reported by a physician from United States on 2012-08-03

Patient: female

Reactions: Hospitalisation, Ill-Defined Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Possible Alimta side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-01

Patient: male, weighing 76.2 kg (167.6 pounds)

Reactions: Hospitalisation, Pleural Effusion, Neoplasm Progression, non-Small Cell Lung Cancer, Metastases To Central Nervous System

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Mucinex; Compazine; Vitamin B-12; Simvastatin; Tylenol / SCH /; Xopenex HFA; Coumadin; Spiriva; Naproxen; Promethazine; Decadron; Prednisone; Hydrocodone; Folic Acid

Possible Alimta side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient: female, weighing 48.0 kg (105.6 pounds)

Reactions: Inappropriate Schedule of Drug Administration, Pneumonia, Anaemia, Mental Status Changes, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 500 mg/m2, q3w
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-05-16
    End date: 2012-05-16

Erlotinib Hydrochloride
    Dosage: 150 mg, days 2-17 of 21 day cycle
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer Metastatic
    Start date: 2012-05-17
    End date: 2012-06-01

Possible Alimta side effects in male

Reported by a physician from France on 2012-07-31

Patient: male

Reactions: Dyspnoea, Haemolytic Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 900 mg, daily
    Indication: Lung Neoplasm Malignant
    Start date: 2012-03-05
    End date: 2012-05-15

Cisplatin
    Dosage: 140 mg, unk
    Start date: 2012-03-05
    End date: 2012-05-15

Dexamethasone
    Dosage: 4 mg, bid
    Administration route: Oral
    Start date: 2012-03-04
    End date: 2012-05-16

Emend
    Dosage: 125 mg, unk
    Administration route: Oral
    Start date: 2012-03-03
    End date: 2012-03-15

Folic Acid
    Dosage: 0.4 mg, daily
    Administration route: Oral
    Start date: 2012-03-01

Lyrica
    Dosage: 100 mg, bid

Methylprednisolone
    Dosage: 120 mg, unk
    Start date: 2012-03-05
    End date: 2012-03-15

Ondansetron
    Dosage: 8 mg, unk
    Start date: 2012-03-03
    End date: 2012-03-15

Oxycodone Hydrochloride
    Dosage: 5 mg, prn
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Oxycontin
    Dosage: 90 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Zometa
    Dosage: unk
    Start date: 2012-05-15
    End date: 2012-05-15