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Alimta (Pemetrexed) - Dehydration - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Dehydration (26)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Alimta (Pemetrexed) where reactions include dehydration. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Alimta side effects in

Reported by a consumer/non-health professional from Italy on 2012-06-25

Patient:

Reactions: Mucosal Inflammation, Vomiting, Diarrhoea, Dehydration, Febrile Neutropenia, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Carboplatin



Possible Alimta side effects in male

Reported by a physician from France on 2012-06-20

Patient: male

Reactions: Malnutrition, General Physical Health Deterioration, Hyponatraemia, Arrhythmia, Hypokalaemia, Multi-Organ Failure, Dehydration, Venous Thrombosis, Colitis

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Candesartan Cilexetil; Oxycontin; Atenolol; Carboplatin; Adalat; Lovenox; Prozac; Fenofibrate



Possible Alimta side effects in male

Reported by a physician from United States on 2012-06-11

Patient: male

Reactions: Pneumonia Aspiration, Vomiting, Viral Infection, Hypotension, Hepatic Failure, Renal Failure, Respiratory Failure, Dehydration, White Blood Cell Analysis Decreased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Cisplatin; Folic Acid



Possible Alimta side effects in male

Reported by a consumer/non-health professional from France on 2012-06-01

Patient: male

Reactions: Sepsis, Dehydration, Colitis, Pancytopenia, Nephrotic Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 1000 mg, unk
    Indication: Lung Adenocarcinoma
    Start date: 2012-02-21

Alimta
    Dosage: 800 mg, unk
    Start date: 2012-03-13

Other drugs received by patient: Cisplatin; Cisplatin; Neulasta



Possible Alimta side effects in male

Reported by a consumer/non-health professional from United States on 2012-05-25

Patient: male, weighing 101.2 kg (222.6 pounds)

Reactions: Agitation, Confusional State, Vomiting, Nausea, Metastases To Meninges, Dehydration, Metastases To Central Nervous System, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 500mg/m2, q 21days, iv
    Indication: non-Small Cell Lung Cancer
    Start date: 2010-04-09

Apricoxib / Placebo
    Dosage: 400mg, daily, po
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer
    Start date: 2010-04-09



Possible Alimta side effects in male

Reported by a physician from United States on 2012-05-18

Patient: male

Reactions: Diarrhoea, Dehydration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Carboplatin



Possible Alimta side effects in female

Reported by a consumer/non-health professional from United States on 2012-03-20

Patient: female

Reactions: Vomiting, Nausea, Dehydration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Carboplatin; Avastin



Possible Alimta side effects in male

Reported by a physician from Japan on 2012-03-02

Patient: male, weighing 82.5 kg (181.5 pounds)

Reactions: Pneumonia Aspiration, Interstitial Lung Disease, Anaemia, Dehydration, Malnutrition, Lymphocyte Stimulation Test Positive, Rash

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Fresmin S; Dextromethorphan Hydrobromide; Zolpidem; Candesartan Cilexetil and Hydrochlorothiazide; Panvitan; Goshajinkigan; Loxonin; Mucosta; Amlodipine



Possible Alimta side effects in female

Reported by a consumer/non-health professional from Italy on 2012-02-21

Patient: female

Reactions: Weight Decreased, Vomiting, Nausea, Dehydration, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Cisplatin



Possible Alimta side effects in male

Reported by a consumer/non-health professional from Japan on 2012-02-21

Patient: male, weighing 82.5 kg (181.5 pounds)

Reactions: Pneumonia Aspiration, Blood Lactate Dehydrogenase Increased, Malnutrition, Neoplasm Progression, Lung Adenocarcinoma Stage IV, Rash, Lymphocyte Stimulation Test Positive, Interstitial Lung Disease, Dehydration

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Zolpidem; Mucosta; Goshajinkigan; Candesartan Cilexetil and Hydrochlorothiazide; Panvitan; Fresmin S; Amlodipine; Dextromethorphan Hydrobromide; Loxonin



Possible Alimta side effects in male

Reported by a physician from Italy on 2012-02-10

Patient: male

Reactions: Anaemia, Febrile Neutropenia, Rash, Ileus Paralytic, Death, Diarrhoea, Dehydration, Abdominal Distension, Thrombocytopenia, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 590 mg/total
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2011-01-13

Alimta
    Dosage: 600 mg, unk
    Start date: 2011-02-10



Possible Alimta side effects in male

Reported by a consumer/non-health professional from Italy on 2012-01-31

Patient: male

Reactions: Nausea, Hypophagia, Dehydration, Rash Papular, Paraesthesia

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Dobetin; Folic Acid; Cisplatin



Possible Alimta side effects in

Reported by a physician from Italy on 2012-01-20

Patient:

Reactions: Vomiting, Dehydration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta



Possible Alimta side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-18

Patient: male, weighing 81.0 kg (178.2 pounds)

Reactions: Mental Status Changes, Oesophageal Ulcer, Blood Creatinine Increased, Renal Failure Acute, Inappropriate Schedule of Drug Administration, Stomatitis, Vomiting, Pneumonia, Nausea, Incorrect Dose Administered, Anaemia, Pancytopenia, Hypoaesthesia, Gastritis Haemorrhagic, Diarrhoea, Hypophagia, Dehydration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Erlotinib Hydrochloride
    Dosage: 100 mg, cyclic (qd days 2-16)
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer Stage IV
    Start date: 2011-04-04
    End date: 2011-10-09

Alimta
    Dosage: 375 mg/m2, q3w
    Indication: non-Small Cell Lung Cancer Stage IV
    Start date: 2011-04-04
    End date: 2011-09-28

Morphine
    Dosage: unk
    Indication: Pain

Other drugs received by patient: Amlodipine; Folic Acid; Citalopram; Zocor; Tamsulosin HCL; Clindamycin; Lomotil; Doxycycline; Gabapentin



Possible Alimta side effects in male

Reported by a physician from United States on 2011-12-23

Patient: male

Reactions: Somnolence, Off Label Use, Haematocrit Decreased, Fatigue, Aspiration, Dizziness, Hypoxia, Vomiting, Alanine Aminotransferase Increased, Sensation of Heaviness, Muscular Weakness, Toxicity To Various Agents, Haemoglobin Decreased, Diarrhoea, Blood Potassium Decreased, Hypophagia, Dehydration, Aspartate Aminotransferase Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Erlotinib Hydrochloride
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Indication: Oropharyngeal Cancer Recurrent
    Start date: 2011-10-12

External Beam Radiation Therapy
    Dosage: weekly, ex. beam
    Indication: Oropharyngeal Cancer Recurrent
    Start date: 2011-10-13

Alimta
    Dosage: unk
    Indication: Oropharyngeal Cancer Recurrent

Miralax
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Erlotinib Hydrochloride
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    End date: 2011-10-28

Other drugs received by patient: Glimepiride; Lidoderm; Oxycodone HCL; Ativan; Folic Acid; Levothyroxine Sodium; Colace; Ativan; Neurontin; Ambien; Duragesic-100; Prochlorperazine Maleate; Zofran; Proair HFA



Possible Alimta side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-13

Patient: male, weighing 81.0 kg (178.2 pounds)

Reactions: Mental Status Changes, Oesophageal Ulcer, Thrombocytopenia, Blood Creatinine Increased, Renal Failure Acute, Inappropriate Schedule of Drug Administration, Pneumonia, Stomatitis, Vomiting, Nausea, Anaemia, Haemoglobin Abnormal, Incorrect Dose Administered, Pancytopenia, Hypoaesthesia, Gastritis Haemorrhagic, Diarrhoea, Hypophagia, Dehydration, Haematocrit Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 375 mg/m2, q3w
    Indication: non-Small Cell Lung Cancer Stage IV
    Start date: 2011-04-04
    End date: 2011-09-28

Morphine
    Dosage: unk
    Indication: Pain

Erlotinib Hydrochloride
    Dosage: 100 mg, cyclic (qd days 2-16)
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer Stage IV
    Start date: 2011-04-04
    End date: 2011-10-09

Other drugs received by patient: Clindamycin; Zocor; Doxycycline; Tamsulosin HCL; Amlodipine; Citalopram; Lomotil; Gabapentin; Folic Acid



Possible Alimta side effects in male

Reported by a physician from United States on 2011-12-12

Patient: male

Reactions: Vomiting, Alanine Aminotransferase Increased, Febrile Neutropenia, Muscular Weakness, Off Label Use, Fatigue, Diarrhoea, Aspiration, Dehydration, Hypophagia, Aspartate Aminotransferase Increased, Hypoxia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: unk
    Indication: Oropharyngeal Cancer Recurrent

External Beam Radiation Therapy
    Dosage: weekly, ex. beam
    Indication: Oropharyngeal Cancer Recurrent
    Start date: 2011-10-13

Miralax
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Erlotinib Hydrochloride
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    End date: 2011-10-28

Erlotinib Hydrochloride
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Indication: Oropharyngeal Cancer Recurrent
    Start date: 2011-10-12

Other drugs received by patient: Colace; Folic Acid; Oxycodone HCL; Ativan; Levothyroxine Sodium; Glimepiride; Zofran; Proair HFA; Neurontin; Prochlorperazine Maleate; Ambien; Lidoderm; Ativan; Duragesic-100



Possible Alimta side effects in male

Reported by a physician from Italy on 2011-11-29

Patient: male

Reactions: Death, Diarrhoea, Anaemia, Dehydration, Febrile Neutropenia, Rash, Thrombocytopenia, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta



Possible Alimta side effects in male

Reported by a consumer/non-health professional from Italy on 2011-11-17

Patient: male

Reactions: Anaemia, Febrile Neutropenia, Rash, Death, Diarrhoea, Dehydration, Thrombocytopenia, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alimta



Possible Alimta side effects in

Reported by a physician from Italy on 2011-11-17

Patient:

Reactions: Weight Decreased, Vomiting, Nausea, Dehydration, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Cisplatin



Possible Alimta side effects in male

Reported by a consumer/non-health professional from United States on 2011-11-11

Patient: male, weighing 63.0 kg (138.7 pounds)

Reactions: Febrile Neutropenia, Pancytopenia, Failure To Thrive, Ascites, Diarrhoea, Neoplasm Malignant, Dehydration, Pleural Effusion, Asthenia, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: unk, unknown
    Start date: 2011-05-26

Alimta
    Dosage: unk unk, unknown
    Start date: 2011-03-17

Alimta
    Dosage: unk, unknown
    Indication: Lung Adenocarcinoma
    Start date: 2011-01-02

Other drugs received by patient: Cisplatin



Possible Alimta side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-10

Patient: male, weighing 81.0 kg (178.2 pounds)

Reactions: Mental Status Changes, Blood Creatinine Increased, Thrombocytopenia, Oesophageal Ulcer, Inappropriate Schedule of Drug Administration, Pneumonia, Stomatitis, Vomiting, Nausea, Incorrect Dose Administered, Haemoglobin Abnormal, Anaemia, Hypoaesthesia, Gastritis Haemorrhagic, Diarrhoea, Hypophagia, Dehydration, Haematocrit Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 375 mg/m2, q3w
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-04
    End date: 2011-09-28

Erlotinib Hydrochloride
    Dosage: 100 mg, cyclic (qd days 2-16)
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-04
    End date: 2011-10-09

Morphine
    Dosage: unk
    Indication: Pain



Possible Alimta side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-26

Patient: female, weighing 43.0 kg (94.6 pounds)

Reactions: Inappropriate Schedule of Drug Administration, Confusional State, Pneumonia, Incorrect Dose Administered, Dehydration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta
    Dosage: 715 mg, q3w
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-06-09
    End date: 2011-08-18

Erlotinib Hydrochloride
    Dosage: 100 mg, days 2-19, cyclic
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-06-10
    End date: 2011-08-25

Other drugs received by patient: Oxygen



Possible Alimta side effects in 36 year old male

Reported by a physician from United States on 2011-10-20

Patient: 36 year old male

Reactions: Productive Cough, Chills, Hypotension, Pain, Off Label Use, Malaise, Dehydration, Sepsis, Dizziness, Asthenia, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Alimta

Other drugs received by patient: Avastin; Oxycodone HCL; Fentanyl; Fentanyl; Marijuana; Erbitux



Possible Alimta side effects in 65 year old male

Reported by a consumer/non-health professional from United States on 2011-10-12

Patient: 65 year old male, weighing 77.0 kg (169.4 pounds)

Reactions: Hyperbilirubinaemia, Haemorrhage, Hypotension, Anaemia, Hypokalaemia, Mucosal Inflammation, Dehydration, Platelet Count Decreased, Hypocalcaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 1df=6auc inter on: 01jun2010.44d; restarted on 06jul2010 (3auc)
    Indication: non-Small Cell Lung Cancer
    Start date: 2010-04-19

Alimta
    Dosage: inter on: 01jun2010.44d; restarted on 06jul2010 (250mg/m2)
    Indication: non-Small Cell Lung Cancer
    Start date: 2010-04-19

Other drugs received by patient: Ciprofloxacin; Emend; Xanax; Folic Acid; Vitamin B-12; Ondansetron HCL



Possible Alimta side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-12

Patient: male, weighing 84.0 kg (184.8 pounds)

Reactions: Pneumonia, Vomiting, Stomatitis, Nausea, Haemoglobin Abnormal, Mental Status Changes, Hypoaesthesia, Diarrhoea, Hypophagia, Dehydration, Thrombocytopenia, Haematocrit Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Erlotinib Hydrochloride
    Dosage: 100 mg, cyclic (qd days 2-16)
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-04
    End date: 2011-09-18

Alimta
    Dosage: 375 mg/m2, q3w
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-04

Morphine
    Dosage: unk
    Indication: Pain

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