This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Alimta (Pemetrexed) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (816)
Death (298)
Life Threatening Events (73)
Disability (24)
Reports by Reaction Type
Death (116),
Neoplasm Progression (81),
Thrombocytopenia (53),
Dyspnoea (49),
Diarrhoea (49),
Interstitial Lung Disease (47),
Anaemia (45),
Pancytopenia (37),
Neutropenia (34),
Pyrexia (33),
Pneumonia (33),
Nausea (32)
Below are a few examples of reports where side effects / adverse reactions may be related to Alimta (Pemetrexed). For a complete list or a specific selection of reports, please use the links above.
Possible Alimta side effects in male
Reported by a consumer/non-health professional from Japan on 2012-08-27
Patient: male, weighing 80.0 kg (176.0 pounds)
Reactions: Off Label Use, White Blood Cell Count Decreased, Neoplasm Progression, Metastases To Bone, Nephrotic Syndrome, Acute Prerenal Failure
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Alimta
Dosage: 750 mg, every 3 weeks
Indication: Pleural Mesothelioma Malignant
Start date: 2009-03-12
End date: 2009-09-24
Gemzar
Dosage: unk
Start date: 2010-05-28
End date: 2010-06-04
Other drugs received by patient: Amlodipine; Vitamin B12; Panvitan; Calblock; Amlodipine; Cisplatin
Possible Alimta side effects in 63 year old female
Reported by a physician from Japan on 2012-08-27
Patient: 63 year old female
Reactions: Pseudomembranous Colitis
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Possible Alimta side effects in 68 year old male
Reported by a consumer/non-health professional from Japan on 2012-08-27
Patient: 68 year old male
Reactions: Interstitial Lung Disease
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Possible Alimta side effects in 85 year old female
Reported by a physician from Japan on 2012-08-27
Patient: 85 year old female
Reactions: Respiratory Failure, Interstitial Lung Disease
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Panvitan; Fresmin
Possible Alimta side effects in female
Reported by a physician from France on 2012-08-24
Patient: female
Reactions: Hepatocellular Injury, Cholestasis, Rash
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Carboplatin; Iressa
Possible Alimta side effects in female
Reported by a physician from Italy on 2012-08-24
Patient: female
Reactions: Lung Disorder, Haemorrhage, Anaemia, Petechiae, Neoplasm Progression, Thrombocytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Folic Acid; Dexamethasone Sodium Phosphate; Dobetin; Benzodiazepine Related Drugs
Possible Alimta side effects in male
Reported by a consumer/non-health professional from Netherlands on 2012-08-23
Patient: male
Reactions: Pulmonary Toxicity, Death
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Omeprazole; Cisplatin; Hydroxocobalamine; Folic Acid
Possible Alimta side effects in 78 year old female
Reported by a consumer/non-health professional from Spain on 2012-08-22
Patient: 78 year old female, weighing 59.0 kg (129.8 pounds)
Reactions: Hepatotoxicity
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Zometa; Folic Acid; Vitamin B-12; Lorazepam; Venoruton; Pantoprazole; Dexamethasone; Magnesium; Escitalopram; Emportal
Possible Alimta side effects in male
Reported by a physician from United States on 2012-08-21
Patient: male
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Possible Alimta side effects in 66 year old female
Reported by a consumer/non-health professional from Germany on 2012-08-17
Patient: 66 year old female
Reactions: Blood Bilirubin Increased, Jaundice, Liver Function Test Abnormal
Drug(s) suspected as cause:
Alimta
Possible Alimta side effects in 58 year old female
Reported by a consumer/non-health professional from Brazil on 2012-08-16
Patient: 58 year old female
Reactions: Abdominal Pain, Toxicity To Various Agents
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Carboplatin
Possible Alimta side effects in male
Reported by a physician from Japan on 2012-08-16
Patient: male, weighing 86.0 kg (189.2 pounds)
Reactions: Pruritus, Neoplasm Malignant, Hypophagia, Bone Marrow Failure, Febrile Neutropenia, Condition Aggravated
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Granisetron; Panvitan; Vitamin B12; Dexamethasone Sodium Phosphate
Possible Alimta side effects in male
Reported by a physician from Japan on 2012-08-15
Patient: male, weighing 61.7 kg (135.7 pounds)
Reactions: C-Reactive Protein Increased, Platelet Count Decreased, Pyrexia, Loss of Consciousness, White Blood Cell Count Increased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Vitamin B12; Panvitan
Possible Alimta side effects in 70 year old male
Reported by a consumer/non-health professional from Japan on 2012-08-15
Patient: 70 year old male
Reactions: Hypersensitivity, C-Reactive Protein Increased, Pyrexia, Neutrophil Count Decreased, Infection
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Vitamin B-12; Folic Acid
Possible Alimta side effects in female
Reported by a physician from France on 2012-08-15
Patient: female
Reactions: Dyspnoea, Nausea, Rash, Hyperhidrosis, Syncope, Epigastric Discomfort, Rash Erythematous, Conjunctival Hyperaemia, Bronchospasm
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: B12-Vitamiin; Methylprednisolone; Polaramine; Avastin; Pravastatin; Acetaminophen; Zofran; Folic Acid; Enalapril Maleate
Possible Alimta side effects in female
Reported by a consumer/non-health professional from Belgium on 2012-08-15
Patient: female, weighing 64.0 kg (140.8 pounds)
Reactions: Death, Off Label Use, Dyspnoea Exertional, Interstitial Lung Disease
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Alimta
Dosage: 500 mg/m2, unknown
Alimta
Dosage: 500 mg/m2, unknown
Indication: Thymoma Malignant
Start date: 2012-01-31
Other drugs received by patient: Dexamethasone; Bisoprolol Fumarate; Vitamin B-12; Folic Acid
Possible Alimta side effects in 47 year old female
Reported by a consumer/non-health professional from Morocco on 2012-08-14
Patient: 47 year old female
Reactions: Rash Generalised, Sepsis
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Vitamins NOS; Cisplatin; Corticosteroid NOS
Possible Alimta side effects in 65 year old male
Reported by a physician from Japan on 2012-08-14
Patient: 65 year old male
Reactions: Death, Renal Disorder, Lung Disorder, Bone Marrow Failure
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Avastin; Carboplatin
Possible Alimta side effects in male
Reported by a physician from Belgium on 2012-08-13
Patient: male
Reactions: Capillary Leak Syndrome, Pleural Effusion, Generalised Oedema
Drug(s) suspected as cause:
Alimta
Possible Alimta side effects in
Reported by a consumer/non-health professional from United States on 2012-08-13
Patient:
Reactions: Death, Neoplasm Progression
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Possible Alimta side effects in male
Reported by a physician from France on 2012-08-13
Patient: male
Reactions: Carcinoembryonic Antigen Increased, Anaemia, Thrombocytopenia, Streptococcal Infection, Renal Failure Chronic
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alimta
Possible Alimta side effects in male
Reported by a consumer/non-health professional from Italy on 2012-08-13
Patient: male
Reactions: Diarrhoea, Hypotension, Depressed Level of Consciousness
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Carboplatin
Possible Alimta side effects in 79 year old female
Reported by a physician from Japan on 2012-08-13
Patient: 79 year old female
Reactions: Interstitial Lung Disease, Rash
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Vitamin B12 / 00056201 /; Folic Acid
Possible Alimta side effects in male
Reported by a physician from France on 2012-08-13
Patient: male
Reactions: Neoplasm Progression, Purpura
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Digoxin; Flecainide Acetate; Janumet; Paroxetine HCL; Previscan; Carboplatin; Atorvastatin; Innohep; Tamsulosin HCL; Permixon
Possible Alimta side effects in 65 year old male
Reported by a consumer/non-health professional from United States on 2012-08-13
Patient: 65 year old male, weighing 67.0 kg (147.4 pounds)
Reactions: Weight Decreased, Mucosal Inflammation, Vomiting
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alimta
Dosage: last dose on 9jul12,375mg/m2
Indication: non-Small Cell Lung Cancer Stage III
Start date: 2012-05-21
Cisplatin
Dosage: last dose on 9jul12,50mg/m2
Indication: non-Small Cell Lung Cancer Stage III
Start date: 2012-05-21
Other drugs received by patient: Dexamethasone; Kytril; Antepsin; Isosorbide Dinitrate; Folic Acid; Vitamin B-12
Possible Alimta side effects in 59 year old
Reported by a physician from Japan on 2012-08-10
Patient: 59 year old
Reactions: Renal Failure, Agranulocytosis, Diarrhoea
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Vitamin B12 / 00056201 /; Folic Acid; Carboplatin
Possible Alimta side effects in
Reported by a physician from Japan on 2012-08-10
Patient:
Reactions: Blood Pressure Increased, Altered State of Consciousness
Drug(s) suspected as cause:
Alimta
Dosage: dosage is uncertain.
Indication: Lung Neoplasm Malignant
Avastin
Indication: Lung Neoplasm Malignant
Start date: 2012-07-24
End date: 2012-07-24
Carboplatin
Dosage: dosage is uncertain.
Indication: Lung Neoplasm Malignant
Other drugs received by patient: Depas; Cerocral
Possible Alimta side effects in 65 year old male
Reported by a consumer/non-health professional from Japan on 2012-08-10
Patient: 65 year old male
Reactions: White Blood Cell Count Decreased, Pruritus, Hypophagia, Platelet Count Decreased
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Possible Alimta side effects in male
Reported by a physician from United States on 2012-08-10
Patient: male
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Alimta
Possible Alimta side effects in male
Reported by a consumer/non-health professional from Netherlands on 2012-08-10
Patient: male
Reactions: Pulmonary Toxicity
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alimta
Other drugs received by patient: Folic Acid; Cisplatin; Hydroxocobalamine; Omeprazole
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