DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Aldactone (Spironolactone) - Lactic Acidosis - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Lactic Acidosis (28)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Aldactone (Spironolactone) where reactions include lactic acidosis. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Aldactone side effects in 72 year old female

Reported by a physician from Switzerland on 2012-06-05

Patient: 72 year old female

Reactions: Nausea, Hyperkalaemia, Hyperglycaemia, Hypotension, Atrioventricular Block Complete, Drug Interaction, Lactic Acidosis, Cardiogenic Shock, Abdominal Pain Upper, Malaise, Dizziness, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glucophage
    Dosage: 1 df, 1x/day
    Administration route: Oral
    End date: 2011-02-27

Aldactone
    Dosage: 1 df, 1x/day
    Administration route: Oral
    End date: 2011-02-27

Enalapril Maleate
    Dosage: unk
    Administration route: Oral

Other drugs received by patient possibly interacting with the suspect drug:
Isoptin
    Dosage: 240 mg, 1x/day
    Administration route: Oral
    Start date: 2011-02-25
    End date: 2011-02-27

Metoprolol Tartrate and Hydrochlorothiazide
    Dosage: 1 df, 1x/day
    Administration route: Oral
    End date: 2011-02-27

Other drugs received by patient: Aspirin; Crestor



Possible Aldactone side effects in male

Reported by a consumer/non-health professional from France on 2012-03-15

Patient: male

Reactions: Lactic Acidosis, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Valsartan
    Dosage: 1 df, daily
    Administration route: Oral

Prednisolone
    Dosage: 20 mg, qd

Propranolol

Aldactone
    Dosage: unk ukn, unk
    Administration route: Oral

Glucophage
    Dosage: unk ukn, unk
    Administration route: Oral
    Indication: Diabetes Mellitus
    End date: 2011-09-24



Possible Aldactone side effects in 59 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-03-05

Patient: 59 year old male

Reactions: Hyperkalaemia, Lactic Acidosis, Generalised Oedema, Cyanosis, Cardiac Failure, Tachypnoea, Bronchitis, Anuria, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Aldactone
    Dosage: unk
    Administration route: Oral

Ramipril
    Dosage: unk
    Administration route: Oral

Metformin HCL
    Dosage: 2250 mg, 1x/day
    Administration route: Oral
    Start date: 1999-01-01
    End date: 2009-02-27

Other drugs received by patient: Lasix; Cordarone; Atorvastatin; Aspegic 1000; Ikorel; Bisoprolol; Previscan; Amlodipine Besylate



Possible Aldactone side effects in 59 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-02-09

Patient: 59 year old male

Reactions: Hyperkalaemia, Lactic Acidosis, Generalised Oedema, Cyanosis, Cardiac Failure, Tachypnoea, Bronchitis, Anuria, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Ramipril
    Dosage: unk
    Administration route: Oral

Aldactone
    Dosage: unk
    Administration route: Oral

Metformin HCL
    Dosage: 2250 mg, 1x/day
    Administration route: Oral
    Start date: 1999-01-01
    End date: 2009-02-27

Other drugs received by patient: Aspegic 325; Ikorel; Cordarone; Lasix; Atorvastatin; Previscan; Bisoprolol; Amlodipine Besylate



Possible Aldactone side effects in 59 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-02-07

Patient: 59 year old male, weighing 107.0 kg (235.4 pounds)

Reactions: Bronchitis, Lactic Acidosis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Metformin HCL
    Dosage: 2550 mg, 1x/day
    Administration route: Oral
    Start date: 1999-01-01
    End date: 2009-02-27

Ramipril
    Administration route: Oral

Aldactone
    Administration route: Oral

Other drugs received by patient: Amlodipine Besylate; Ikorel; Previscan; Lasix; Cordarone; Bisoprolol; Atorvastatin; Aspegic 325



Possible Aldactone side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-02-06

Patient: 76 year old male

Reactions: Diarrhoea, Hyperkalaemia, Ventricular Tachycardia, Oedema Peripheral, Orthopnoea, Lactic Acidosis, Cardiac Arrest, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aldactone
    Dosage: unk
    Administration route: Oral

Metformin HCL
    Dosage: unk
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus

Ramipril
    Dosage: unk
    Administration route: Oral

Other drugs received by patient: Amaryl; Furosemide; Nitroglycerin; Adancor



Possible Aldactone side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) on 2012-02-03

Patient: 76 year old male

Reactions: Hyperkalaemia, Lactic Acidosis, Cardio-Respiratory Arrest, Diarrhoea, Ventricular Tachycardia, Oedema Peripheral, Orthopnoea, Platelet Count Decreased, Cardiac Arrest, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Metformin HCL
    Dosage: oral
    Administration route: Oral
    Indication: Diabetes Mellitus
    End date: 2008-02-08

Ramipril
    Dosage: oral
    Administration route: Oral
    Indication: Hypertension
    End date: 2008-02-08

Aldactone
    Dosage: oral
    Administration route: Oral
    Indication: Hypertension
    End date: 2008-02-08

Other drugs received by patient: Furosemide; Amaryl; Cordipatch (Glyceryl Trinitrate); Adancor (Nicorandil)



Possible Aldactone side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-30

Patient: 76 year old male

Reactions: Cardio-Respiratory Arrest, Diarrhoea, Ventricular Tachycardia, Lactic Acidosis, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Metformin HCL
    Dosage: oral
    Administration route: Oral
    Indication: Diabetes Mellitus
    End date: 2008-02-08

Ramipril
    Dosage: oral
    Administration route: Oral
    Indication: Hypertension
    End date: 2008-02-08

Aldactone
    Dosage: oral
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-02-08

Other drugs received by patient: Furosemide; Amaryl; Cordipatch (Glyceryl Trinitrate); Adancor (Nicorandil)



Possible Aldactone side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-26

Patient: 76 year old male

Reactions: Hyperkalaemia, Diarrhoea, Ventricular Tachycardia, Oedema Peripheral, Orthopnoea, Lactic Acidosis, Cardiac Arrest, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ramipril
    Dosage: unk
    Administration route: Oral
    Indication: Hypertension
    End date: 2008-02-08

Aldactone
    Dosage: unk
    Administration route: Oral
    Indication: Hypertension
    End date: 2008-02-08

Metformin HCL
    Dosage: unk
    Administration route: Oral
    Indication: Diabetes Mellitus
    End date: 2008-02-08

Other drugs received by patient: Nitroglycerin; Adancor; Amaryl; Furosemide



Possible Aldactone side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-24

Patient: male

Reactions: Lactic Acidosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Aldactone
    Dosage: unknown
    Administration route: Oral

Glucophage
    Dosage: unk
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-09-24

Valsartan
    Dosage: 160 mg, 1x/day
    Administration route: Oral

Other drugs received by patient: Propranolol; Prednisolone



Possible Aldactone side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-24

Patient: 76 year old male

Reactions: Hyperkalaemia, Lactic Acidosis, Cardio-Respiratory Arrest, Diarrhoea, Oedema Peripheral, Ventricular Tachycardia, Orthopnoea, Platelet Count Decreased, Cardiac Arrest, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aldactone
    Dosage: unk
    Administration route: Oral
    Indication: Hypertension
    End date: 2008-02-08

Ramipril
    Dosage: unk
    Administration route: Oral
    End date: 2008-02-08

Metformin HCL
    Dosage: unk
    Administration route: Oral
    Indication: Diabetes Mellitus
    End date: 2008-02-08

Other drugs received by patient: Furosemide; Nitroglycerin; Amaryl; Adancor



Possible Aldactone side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-24

Patient: 76 year old male

Reactions: Diarrhoea, Hyperkalaemia, Ventricular Tachycardia, Oedema Peripheral, Orthopnoea, Lactic Acidosis, Cardiac Arrest, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ramipril
    Dosage: unk
    Administration route: Oral

Aldactone
    Dosage: unk
    Administration route: Oral

Metformin HCL
    Dosage: unk
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus

Other drugs received by patient: Adancor; Amaryl; Furosemide; Nitroglycerin



Possible Aldactone side effects in 61 year old male

Reported by a consumer/non-health professional from Germany on 2012-01-18

Patient: 61 year old male

Reactions: Lactic Acidosis, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Valsartan
    Dosage: formulation-tablet
    Administration route: Oral

Glucophage
    Dosage: formulation-tablet
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-09-24

Aldactone
    Dosage: therapy stopped
    Administration route: Oral

Propranolol
    Administration route: Oral

Prednisolone



Possible Aldactone side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-13

Patient: 61 year old male

Reactions: Lactic Acidosis, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Propranolol
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Diovan HCT
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Prednisolone
    Dosage: 20 mg (20 mg, 1 in 1 d), oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Valsartan
    Dosage: 160 mg (160 mg, 1 in 1 d), oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Glucophage
    Dosage: oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-09-24

Aldactone
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Aldactone side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-11

Patient: male

Reactions: Lactic Acidosis, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Glucophage
    Dosage: unk ukn, unk
    Administration route: Oral
    Indication: Diabetes Mellitus
    End date: 2011-09-24

Prednisolone
    Dosage: 20 mg, qd

Propranolol

Valsartan
    Dosage: 1 df, daily
    Administration route: Oral

Aldactone
    Dosage: unk ukn, unk
    Administration route: Oral



Possible Aldactone side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-09

Patient: 61 year old male

Reactions: Lactic Acidosis, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Aldactone
    Dosage: unknown
    Administration route: Oral

Glucophage
    Dosage: unk
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-09-24

Glucophage
    Indication: Diabetes Mellitus

Prednisolone
    Dosage: 20 mg, 1x/day
    Administration route: Oral

Galenic / Hydrochlorothiazide / Valsartan /
    Dosage: unknown
    Administration route: Oral

Propranolol
    Dosage: unknown
    Administration route: Oral

Valsartan
    Dosage: 160 mg, 1x/day
    Administration route: Oral



Possible Aldactone side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-09

Patient: 61 year old male

Reactions: Lactic Acidosis, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Prednisolone
    Dosage: 20 mg (20 mg, 1 in 1 d), oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Metformin HCL
    Dosage: oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-09-24

Aldactone
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Propranolol
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Diovan HCT
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Aldactone side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-09

Patient: 61 year old male

Reactions: Lactic Acidosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Aldactone
    Dosage: unknown
    Administration route: Oral

Glucophage
    Dosage: unk
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-09-24

Valsartan
    Dosage: 160 mg, 1x/day
    Administration route: Oral

Other drugs received by patient: Prednisolone; Propranolol



Possible Aldactone side effects in 61 year old male

Reported by a consumer/non-health professional from Germany on 2012-01-06

Patient: 61 year old male

Reactions: Lactic Acidosis, Septic Shock

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glucophage
    Dosage: formulation-tablet
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-09-24

Aldactone
    Dosage: therapy stopped
    Administration route: Oral

Valsartan
    Dosage: formulation-tablet
    Administration route: Oral

Other drugs received by patient: Prednisolone; Propranolol



Possible Aldactone side effects in male

Reported by a individual with unspecified qualification from France on 2012-01-05

Patient: male

Reactions: Lactic Acidosis, Septic Shock, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Aldactone
    Administration route: Oral

Glucophage
    Administration route: Oral
    Indication: Diabetes Mellitus
    End date: 2011-09-24

Valsartan
    Dosage: 1 df, daily
    Administration route: Oral

Other drugs received by patient: Prednisolone; Propranolol



Possible Aldactone side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-04

Patient: 61 year old male

Reactions: Lactic Acidosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Aldactone
    Dosage: unknown
    Administration route: Oral

Valsartan
    Dosage: 160 mg, 1x/day
    Administration route: Oral

Glucophage
    Dosage: unk
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-09-24

Other drugs received by patient: Propranolol; Prednisolone



Possible Aldactone side effects in 73 year old female

Reported by a physician from Spain on 2012-01-03

Patient: 73 year old female

Reactions: Metabolic Acidosis, Dehydration, Drug Interaction, Lactic Acidosis, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Ibuprofen
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-01
    End date: 2011-08-01

Metformin HCL
    Dosage: (850 mg, 1 d), oral
    Administration route: Oral
    Indication: Diabetes Mellitus
    Start date: 2011-04-01
    End date: 2011-09-08

Aldactone
    Dosage: (25 mg, 1 d), oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-01-01
    End date: 2011-09-08

Enalapril Maleate
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-05-01
    End date: 2011-09-08



Possible Aldactone side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) on 2011-12-07

Patient: 61 year old male

Reactions: Lactic Acidosis, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Propranolol
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Prednisolone
    Dosage: 20 mg (20 mg, 1 in 1 d), oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Metformin HCL
    Dosage: oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-09-24

Diovan HCT
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Aldactone
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Aldactone side effects in 73 year old female

Reported by a physician from Spain on 2011-12-07

Patient: 73 year old female

Reactions: Hyperkalaemia, Drug Interaction, General Physical Health Deterioration, Lactic Acidosis, Blood Sodium Decreased, Haemodialysis, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Aldactone
    Dosage: 25 mg, 1 d, oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-01-01
    End date: 2010-09-08

Enalapril Maleate
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-05-01
    End date: 2011-09-08

Ibuprofen
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-01
    End date: 2011-08-01

Metformin HCL
    Dosage: 850 mg, 1 d, oral
    Administration route: Oral
    Indication: Diabetes Mellitus
    Start date: 2011-04-01
    End date: 2011-09-08



Possible Aldactone side effects in 71 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2011-11-08

Patient: 71 year old female

Reactions: Confusional State, Hyperkalaemia, Electrocardiogram QRS Complex Prolonged, Dehydration, Lactic Acidosis, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Atacand
    Dosage: formu: 16mg tabs
    Administration route: Oral
    Indication: Hypertension
    End date: 2011-07-21

Aldactone
    Dosage: form: 25mg tabs
    Administration route: Oral
    Indication: Cardiac Failure
    End date: 2011-07-21

Glucophage
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-07-21

Sectral
    Dosage: form: 200mg tabs
    Administration route: Oral
    Indication: Hypertension
    End date: 2011-07-21

Other drugs received by patient: Rabeprazole Sodium; Previscan; Lasix; Calcium Carbonate; Cordarone



Possible Aldactone side effects in female

Reported by a physician from France on 2011-10-26

Patient: female

Reactions: Confusional State, Lactic Acidosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Aldactone
    Administration route: Oral
    Indication: Cardiac Failure
    End date: 2011-07-21

Atacand
    Administration route: Oral
    Indication: Hypertension
    End date: 2011-07-21

Sectral
    Administration route: Oral
    Indication: Hypertension
    End date: 2011-07-21

Glucophage
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-07-21

Other drugs received by patient: Cordarone; Rabeprazole Sodium; Lasix; Previscan; Cacit Vitamine D3



Possible Aldactone side effects in 71 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2011-10-25

Patient: 71 year old female

Reactions: Confusional State, Electrocardiogram QRS Complex Prolonged, Diarrhoea, Hyperkalaemia, Dehydration, Lactic Acidosis, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Aldactone
    Dosage: 25 mg, 1x/day
    Administration route: Oral
    Indication: Cardiac Failure
    End date: 2011-07-21

Atacand
    Dosage: 16 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    End date: 2011-07-21

Glucophage
    Dosage: 850 mg, 3x/day
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-07-21

Sectral
    Dosage: 200 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    End date: 2011-07-21

Other drugs received by patient: Calcium Carbonate; Lasix; Previscan; Rabeprazole Sodium; Cordarone



Possible Aldactone side effects in 71 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2011-10-20

Patient: 71 year old female

Reactions: Confusional State, Electrocardiogram QRS Complex Prolonged, Diarrhoea, Hyperkalaemia, Dehydration, Lactic Acidosis, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Atacand
    Dosage: 16 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    End date: 2011-07-21

Glucophage
    Dosage: 850 mg, 3x/day
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2011-07-21

Aldactone
    Dosage: 25 mg, 1x/day
    Administration route: Oral
    Indication: Cardiac Failure
    End date: 2011-07-21

Sectral
    Dosage: 200 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    End date: 2011-07-21

Other drugs received by patient: Previscan; Calcium Carbonate; Rabeprazole Sodium; Cordarone; Lasix

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017