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Afinitor (Everolimus) - General Physical Health Deterioration - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with General Physical Health Deterioration ()

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Afinitor (Everolimus) where reactions include general physical health deterioration. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of    Next >>

Possible Afinitor side effects in female

Reported by a physician from Germany on 2012-08-24

Patient: female, weighing 91.0 kg (200.2 pounds)

Reactions: Vomiting, General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in male

Reported by a consumer/non-health professional from Canada on 2012-08-08

Patient: male

Reactions: Weight Decreased, White Blood Cell Count Decreased, Jaundice, Impaired Work Ability, General Physical Health Deterioration, Neoplasm Progression, Device Occlusion, Hepatic Enzyme Increased, Liver Disorder, Abdominal Discomfort, Haemoglobin Decreased, Fatigue, Platelet Count Decreased, Neutrophil Count Decreased, Neuroendocrine Tumour

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, every other day (for a month)
    Administration route: Oral

Afinitor
    Dosage: 5 mg, unk
    Administration route: Oral
    Start date: 2011-10-27
    End date: 2012-04-23

Afinitor
    Dosage: 10 mg, every day
    Administration route: Oral
    Indication: Neuroendocrine Carcinoma Metastatic
    Start date: 2011-10-15

Sandostatin LAR
    Dosage: 30 mg, every 4 weeks
    Indication: Neuroendocrine Tumour
    Start date: 2011-07-14

Other drugs received by patient: Pancrease; Dexamethasone; Gabapentin; Pantoprazole Sodium



Possible Afinitor side effects in 61 year old female

Reported by a physician from Japan on 2012-08-07

Patient: 61 year old female, weighing 45.1 kg (99.3 pounds)

Reactions: Growth Hormone-Producing Pituitary Tumour, Swelling Face, Interstitial Lung Disease, Hyperglycaemia, Tongue Pigmentation, Neoplasm Progression, General Physical Health Deterioration

Drug(s) suspected as cause:
Afinitor
    Dosage: unk
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-01-01

Sandostatin LAR
    Dosage: unk
    Indication: Growth Hormone-Producing Pituitary Tumour



Possible Afinitor side effects in 70 year old female

Reported by a pharmacist from Japan on 2012-07-30

Patient: 70 year old female

Reactions: Vomiting, Nausea, General Physical Health Deterioration, Pleural Effusion, Headache, Concomitant Disease Progression, Decreased Appetite

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Narcotics



Possible Afinitor side effects in 64 year old male

Reported by a physician from Israel on 2012-07-26

Patient: 64 year old male

Reactions: Metastasis, Neoplasm Malignant, Neoplasm Progression, General Physical Health Deterioration

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Carcinoid Tumour

Sandostatin LAR
    Dosage: 30 mg once in every 28 days
    Start date: 2012-06-13

Sandostatin LAR
    Dosage: 30 mg once in every 28 days
    Indication: Carcinoid Tumour
    Start date: 2009-07-06



Possible Afinitor side effects in male

Reported by a health professional (non-physician/pharmacist) from Czech Republic on 2012-07-05

Patient: male

Reactions: Pancreatic Disorder, General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in 70 year old female

Reported by a physician from Germany on 2012-07-05

Patient: 70 year old female

Reactions: Dyspnoea, Fatigue, Anaemia, General Physical Health Deterioration, Pleural Effusion, Asthenia, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg per day
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2012-05-26
    End date: 2012-05-30

Afinitor
    Dosage: daily alternating schedule of 10 mg and 5 mg dose
    Administration route: Oral
    Start date: 2012-06-07
    End date: 2012-06-13

Afinitor
    Dosage: 5 mg, every other day
    Start date: 2012-06-07
    End date: 2012-06-13



Possible Afinitor side effects in female

Reported by a health professional (non-physician/pharmacist) from Greece on 2012-06-29

Patient: female

Reactions: Aphagia, Dyspnoea, Vomiting, Metabolic Acidosis, Nausea, Neoplasm Progression, General Physical Health Deterioration, Neoplasm Malignant, Oliguria, Asthenia, Thrombocytopenia, Renal Failure Acute, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-04-10
    End date: 2012-05-16

Afinitor
    Dosage: 10 mg, qd
    Administration route: Oral
    Start date: 2012-06-06

Other drugs received by patient: Aromasin; Konakion



Possible Afinitor side effects in male

Reported by a consumer/non-health professional from Canada on 2012-06-29

Patient: male

Reactions: Blood Creatine Phosphokinase Increased, Contusion, Injection Site Pain, General Physical Health Deterioration, Fall, Polymyositis, Road Traffic Accident, Malaise, Diarrhoea, Gait Disturbance, Feeling Abnormal, Ligament Sprain

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: unk
    End date: 2012-01-01

Afinitor
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-07-12
    End date: 2011-10-10

Sandostatin LAR
    Dosage: 40 mg, qmo

Sandostatin LAR
    Dosage: 30 mg, qmo
    Indication: Pancreatic Neuroendocrine Tumour Metastatic
    Start date: 2011-08-31



Possible Afinitor side effects in female

Reported by a health professional (non-physician/pharmacist) from Greece on 2012-06-28

Patient: female

Reactions: Aphagia, Vomiting, Dyspnoea, Nausea, General Physical Health Deterioration, Oliguria, Asthenia, Thrombocytopenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, qd
    Administration route: Oral
    Start date: 2012-06-06

Afinitor
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-04-10
    End date: 2012-05-16

Other drugs received by patient: Aromasin; Konakion



Possible Afinitor side effects in male

Reported by a physician from United States on 2012-06-26

Patient: male

Reactions: Fatigue, Neoplasm Malignant, General Physical Health Deterioration, Neoplasm Progression, Hypercalcaemia of Malignancy, Gastric Cancer

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-06-20

Patient: male

Reactions: Contusion, Blood Creatine Phosphokinase Increased, General Physical Health Deterioration, Injection Site Pain, Fall, Malaise, Road Traffic Accident, Polymyositis, Diarrhoea, Feeling Abnormal, Ligament Sprain

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-07-12
    End date: 2011-10-10

Sandostatin LAR
    Dosage: 40 mg, qmo
    Indication: Pancreatic Neuroendocrine Tumour Metastatic
    Start date: 2011-08-31

Sandostatin LAR
    Dosage: 40 mg, qmo



Possible Afinitor side effects in male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-06-20

Patient: male

Reactions: Neoplasm Malignant, Neoplasm Progression, General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in 70 year old female

Reported by a physician from Germany on 2012-06-19

Patient: 70 year old female

Reactions: Fatigue, Anaemia, General Physical Health Deterioration, Asthenia

Drug(s) suspected as cause:
Afinitor
    Dosage: daily alternating schedule of 10 mg and 5 mg dose
    Administration route: Oral
    Start date: 2012-06-07
    End date: 2012-06-13

Afinitor
    Dosage: 10 mg per day
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2012-05-26
    End date: 2012-05-30



Possible Afinitor side effects in 61 year old female

Reported by a physician from Japan on 2012-06-11

Patient: 61 year old female, weighing 45.1 kg (99.3 pounds)

Reactions: Swelling Face, Neoplasm Malignant, Interstitial Lung Disease, Tongue Pigmentation, Hyperglycaemia, General Physical Health Deterioration, Neoplasm Progression

Drug(s) suspected as cause:
Afinitor
    Dosage: unk
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-01-01

Sandostatin LAR
    Dosage: unk
    Indication: Growth Hormone-Producing Pituitary Tumour



Possible Afinitor side effects in female

Reported by a health professional (non-physician/pharmacist) from Greece on 2012-05-31

Patient: female

Reactions: Aphagia, Dyspnoea, Vomiting, Nausea, General Physical Health Deterioration, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Aromasin; Konakion



Possible Afinitor side effects in female

Reported by a physician from Germany on 2012-05-25

Patient: female, weighing 61.0 kg (134.2 pounds)

Reactions: Pneumonia, Blood Lactate Dehydrogenase Increased, General Physical Health Deterioration, Haemoglobin Decreased, Fatigue, Renal Impairment, Dehydration, Blood Creatinine Increased, Renal Failure Acute, Infection, Influenza

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Levothyroxine Sodium; Irbesartan; Metoclopramide; Omeprazole; ACE Inhibitor NOS



Possible Afinitor side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-04

Patient: male

Reactions: General Physical Health Deterioration

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in male

Reported by a consumer/non-health professional from Colombia on 2012-04-27

Patient: male

Reactions: Death, General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in male

Reported by a physician from Italy on 2012-04-17

Patient: male, weighing 70.0 kg (154.0 pounds)

Reactions: General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in female

Reported by a physician from Germany on 2012-04-16

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: Pneumonia, Chest Discomfort, Anaemia, General Physical Health Deterioration, Febrile Neutropenia, Pyrexia, Gastrointestinal Infection, Renal Failure

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 5 mg, qd
    Administration route: Oral
    Indication: Acute Myeloid Leukaemia
    Start date: 2010-05-30

Prednisolone

Tasigna
    Dosage: unk
    Administration route: Oral
    Start date: 2010-07-13

Tasigna
    Dosage: 400 mg, qd
    Administration route: Oral
    Indication: Acute Myeloid Leukaemia
    Start date: 2010-05-03
    End date: 2010-06-19

Other drugs received by patient: Norvasc; Bisoprolol Fumarate; Pantoprazole; Delix; Seroquel; Lantus; Vitamin D; Cefuroxime; Hydrochlorothiazide; Glucobay



Possible Afinitor side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-03

Patient: male

Reactions: General Physical Health Deterioration

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in male

Reported by a physician from Germany on 2012-03-29

Patient: male, weighing 61.0 kg (134.2 pounds)

Reactions: Pneumonia, General Physical Health Deterioration, Neoplasm Progression, Disorientation, Cachexia, Multi-Organ Failure, Hypokinesia, Neoplasm Malignant, Breath Sounds Abnormal, Sepsis, Oedema Peripheral, Dehydration, Breath Odour, Altered State of Consciousness, Oxygen Saturation Decreased

Adverse event resulted in: death

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2011-01-05
    End date: 2011-02-18

Sterofundin
    Dosage: 1.5 l, per day
    Indication: Dehydration

Other drugs received by patient: TPN; Dexametason



Possible Afinitor side effects in male

Reported by a physician from Germany on 2012-03-26

Patient: male

Reactions: Weight Decreased, Neoplasm Malignant, General Physical Health Deterioration, Neoplasm Progression, Asthenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, unk
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2011-05-02
    End date: 2011-10-24

Zometa
    Dosage: 4 mg/5ml
    Indication: Bone Disorder
    Start date: 2010-11-22

Other drugs received by patient: Sunitinib Malate; Metoprolol Succinate; Calcium Carbonate; Amlodipine; Votrient; Vitamin D



Possible Afinitor side effects in male

Reported by a consumer/non-health professional from Colombia on 2012-03-23

Patient: male

Reactions: Death, General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in 70 year old male

Reported by a physician from Spain on 2012-03-19

Patient: 70 year old male

Reactions: Confusional State, Metabolic Acidosis, General Physical Health Deterioration, Coma, Encephalopathy, Disorientation, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Aerosols; Enalapril; Somatuline Depot



Possible Afinitor side effects in male

Reported by a physician from Spain on 2012-03-15

Patient: male

Reactions: Encephalopathy, General Physical Health Deterioration

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in male

Reported by a physician from Spain on 2012-03-12

Patient: male

Reactions: General Physical Health Deterioration, Encephalopathy

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in 73 year old male

Reported by a physician from Israel on 2012-03-02

Patient: 73 year old male

Reactions: Dyspnoea, Blood Pressure Systolic Increased, General Physical Health Deterioration, Pyrexia, Cardiomyopathy, Renal Failure, Aspiration, Cyanosis, Cyanosis Central, Blood Creatinine Increased, Cardiac Failure Congestive, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in male

Reported by a consumer/non-health professional from United States on 2012-03-01

Patient: male

Reactions: Lung Disorder, General Physical Health Deterioration, Fall, RIB Fracture

Adverse event resulted in: death

Drug(s) suspected as cause:
Afinitor
    Indication: Benign Neoplasm of Islets of Langerhans

Afinitor
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Malignant Neoplasm of Islets of Langerhans



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