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Index of reports
> Cases with General Physical Health Deterioration ()
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Afinitor (Everolimus) where reactions include general physical health deterioration. The selected reports were submitted to the FDA during the sample period of about a year. Reports 1 - 30 of Next >>
Possible Afinitor side effects in female
Reported by a physician from Germany on 2012-08-24
Patient: female, weighing 91.0 kg (200.2 pounds)
Reactions: Vomiting, General Physical Health Deterioration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in male
Reported by a consumer/non-health professional from Canada on 2012-08-08
Patient: male
Reactions: Weight Decreased, White Blood Cell Count Decreased, Jaundice, Impaired Work Ability, General Physical Health Deterioration, Neoplasm Progression, Device Occlusion, Hepatic Enzyme Increased, Liver Disorder, Abdominal Discomfort, Haemoglobin Decreased, Fatigue, Platelet Count Decreased, Neutrophil Count Decreased, Neuroendocrine Tumour
Drug(s) suspected as cause:
Afinitor
Dosage: 10 mg, every other day (for a month)
Administration route: Oral
Afinitor
Dosage: 5 mg, unk
Administration route: Oral
Start date: 2011-10-27
End date: 2012-04-23
Afinitor
Dosage: 10 mg, every day
Administration route: Oral
Indication: Neuroendocrine Carcinoma Metastatic
Start date: 2011-10-15
Sandostatin LAR
Dosage: 30 mg, every 4 weeks
Indication: Neuroendocrine Tumour
Start date: 2011-07-14
Other drugs received by patient: Pancrease; Dexamethasone; Gabapentin; Pantoprazole Sodium
Possible Afinitor side effects in 61 year old female
Reported by a physician from Japan on 2012-08-07
Patient: 61 year old female, weighing 45.1 kg (99.3 pounds)
Reactions: Growth Hormone-Producing Pituitary Tumour, Swelling Face, Interstitial Lung Disease, Hyperglycaemia, Tongue Pigmentation, Neoplasm Progression, General Physical Health Deterioration
Drug(s) suspected as cause:
Afinitor
Dosage: unk
Indication: Pancreatic Neuroendocrine Tumour
Start date: 2011-01-01
Sandostatin LAR
Dosage: unk
Indication: Growth Hormone-Producing Pituitary Tumour
Possible Afinitor side effects in 70 year old female
Reported by a pharmacist from Japan on 2012-07-30
Patient: 70 year old female
Reactions: Vomiting, Nausea, General Physical Health Deterioration, Pleural Effusion, Headache, Concomitant Disease Progression, Decreased Appetite
Drug(s) suspected as cause:
Afinitor
Other drugs received by patient: Narcotics
Possible Afinitor side effects in 64 year old male
Reported by a physician from Israel on 2012-07-26
Patient: 64 year old male
Reactions: Metastasis, Neoplasm Malignant, Neoplasm Progression, General Physical Health Deterioration
Drug(s) suspected as cause:
Afinitor
Dosage: 10 mg, daily
Administration route: Oral
Indication: Carcinoid Tumour
Sandostatin LAR
Dosage: 30 mg once in every 28 days
Start date: 2012-06-13
Sandostatin LAR
Dosage: 30 mg once in every 28 days
Indication: Carcinoid Tumour
Start date: 2009-07-06
Possible Afinitor side effects in 70 year old female
Reported by a physician from Germany on 2012-07-05
Patient: 70 year old female
Reactions: Dyspnoea, Fatigue, Anaemia, General Physical Health Deterioration, Pleural Effusion, Asthenia, Pneumonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: 10 mg per day
Administration route: Oral
Indication: Renal Cell Carcinoma
Start date: 2012-05-26
End date: 2012-05-30
Afinitor
Dosage: daily alternating schedule of 10 mg and 5 mg dose
Administration route: Oral
Start date: 2012-06-07
End date: 2012-06-13
Afinitor
Dosage: 5 mg, every other day
Start date: 2012-06-07
End date: 2012-06-13
Possible Afinitor side effects in male
Reported by a health professional (non-physician/pharmacist) from Czech Republic on 2012-07-05
Patient: male
Reactions: Pancreatic Disorder, General Physical Health Deterioration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in male
Reported by a consumer/non-health professional from Canada on 2012-06-29
Patient: male
Reactions: Blood Creatine Phosphokinase Increased, Contusion, Injection Site Pain, General Physical Health Deterioration, Fall, Polymyositis, Road Traffic Accident, Malaise, Diarrhoea, Gait Disturbance, Feeling Abnormal, Ligament Sprain
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: unk
End date: 2012-01-01
Afinitor
Dosage: 10 mg, qd
Administration route: Oral
Indication: Pancreatic Neuroendocrine Tumour
Start date: 2011-07-12
End date: 2011-10-10
Sandostatin LAR
Dosage: 40 mg, qmo
Sandostatin LAR
Dosage: 30 mg, qmo
Indication: Pancreatic Neuroendocrine Tumour Metastatic
Start date: 2011-08-31
Possible Afinitor side effects in female
Reported by a health professional (non-physician/pharmacist) from Greece on 2012-06-29
Patient: female
Reactions: Aphagia, Dyspnoea, Vomiting, Metabolic Acidosis, Nausea, Neoplasm Progression, General Physical Health Deterioration, Neoplasm Malignant, Oliguria, Asthenia, Thrombocytopenia, Renal Failure Acute, Decreased Appetite
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: 10 mg, qd
Administration route: Oral
Indication: Breast Cancer
Start date: 2012-04-10
End date: 2012-05-16
Afinitor
Dosage: 10 mg, qd
Administration route: Oral
Start date: 2012-06-06
Other drugs received by patient: Aromasin; Konakion
Possible Afinitor side effects in female
Reported by a health professional (non-physician/pharmacist) from Greece on 2012-06-28
Patient: female
Reactions: Aphagia, Vomiting, Dyspnoea, Nausea, General Physical Health Deterioration, Oliguria, Asthenia, Thrombocytopenia, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: 10 mg, qd
Administration route: Oral
Start date: 2012-06-06
Afinitor
Dosage: 10 mg, qd
Administration route: Oral
Indication: Breast Cancer
Start date: 2012-04-10
End date: 2012-05-16
Other drugs received by patient: Aromasin; Konakion
Possible Afinitor side effects in male
Reported by a physician from United States on 2012-06-26
Patient: male
Reactions: Fatigue, Neoplasm Malignant, General Physical Health Deterioration, Neoplasm Progression, Hypercalcaemia of Malignancy, Gastric Cancer
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in male
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-06-20
Patient: male
Reactions: Contusion, Blood Creatine Phosphokinase Increased, General Physical Health Deterioration, Injection Site Pain, Fall, Malaise, Road Traffic Accident, Polymyositis, Diarrhoea, Feeling Abnormal, Ligament Sprain
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: 10 mg, qd
Administration route: Oral
Indication: Pancreatic Neuroendocrine Tumour
Start date: 2011-07-12
End date: 2011-10-10
Sandostatin LAR
Dosage: 40 mg, qmo
Indication: Pancreatic Neuroendocrine Tumour Metastatic
Start date: 2011-08-31
Sandostatin LAR
Dosage: 40 mg, qmo
Possible Afinitor side effects in male
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-06-20
Patient: male
Reactions: Neoplasm Malignant, Neoplasm Progression, General Physical Health Deterioration
Adverse event resulted in: death
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in 70 year old female
Reported by a physician from Germany on 2012-06-19
Patient: 70 year old female
Reactions: Fatigue, Anaemia, General Physical Health Deterioration, Asthenia
Drug(s) suspected as cause:
Afinitor
Dosage: daily alternating schedule of 10 mg and 5 mg dose
Administration route: Oral
Start date: 2012-06-07
End date: 2012-06-13
Afinitor
Dosage: 10 mg per day
Administration route: Oral
Indication: Renal Cell Carcinoma
Start date: 2012-05-26
End date: 2012-05-30
Possible Afinitor side effects in 61 year old female
Reported by a physician from Japan on 2012-06-11
Patient: 61 year old female, weighing 45.1 kg (99.3 pounds)
Reactions: Swelling Face, Neoplasm Malignant, Interstitial Lung Disease, Tongue Pigmentation, Hyperglycaemia, General Physical Health Deterioration, Neoplasm Progression
Drug(s) suspected as cause:
Afinitor
Dosage: unk
Indication: Pancreatic Neuroendocrine Tumour
Start date: 2011-01-01
Sandostatin LAR
Dosage: unk
Indication: Growth Hormone-Producing Pituitary Tumour
Possible Afinitor side effects in female
Reported by a health professional (non-physician/pharmacist) from Greece on 2012-05-31
Patient: female
Reactions: Aphagia, Dyspnoea, Vomiting, Nausea, General Physical Health Deterioration, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Other drugs received by patient: Aromasin; Konakion
Possible Afinitor side effects in female
Reported by a physician from Germany on 2012-05-25
Patient: female, weighing 61.0 kg (134.2 pounds)
Reactions: Pneumonia, Blood Lactate Dehydrogenase Increased, General Physical Health Deterioration, Haemoglobin Decreased, Fatigue, Renal Impairment, Dehydration, Blood Creatinine Increased, Renal Failure Acute, Infection, Influenza
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Afinitor
Other drugs received by patient: Levothyroxine Sodium; Irbesartan; Metoclopramide; Omeprazole; ACE Inhibitor NOS
Possible Afinitor side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-04
Patient: male
Reactions: General Physical Health Deterioration
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in male
Reported by a consumer/non-health professional from Colombia on 2012-04-27
Patient: male
Reactions: Death, General Physical Health Deterioration
Adverse event resulted in: death
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in male
Reported by a physician from Italy on 2012-04-17
Patient: male, weighing 70.0 kg (154.0 pounds)
Reactions: General Physical Health Deterioration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in female
Reported by a physician from Germany on 2012-04-16
Patient: female, weighing 54.0 kg (118.8 pounds)
Reactions: Pneumonia, Chest Discomfort, Anaemia, General Physical Health Deterioration, Febrile Neutropenia, Pyrexia, Gastrointestinal Infection, Renal Failure
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: 5 mg, qd
Administration route: Oral
Indication: Acute Myeloid Leukaemia
Start date: 2010-05-30
Prednisolone
Tasigna
Dosage: unk
Administration route: Oral
Start date: 2010-07-13
Tasigna
Dosage: 400 mg, qd
Administration route: Oral
Indication: Acute Myeloid Leukaemia
Start date: 2010-05-03
End date: 2010-06-19
Other drugs received by patient: Norvasc; Bisoprolol Fumarate; Pantoprazole; Delix; Seroquel; Lantus; Vitamin D; Cefuroxime; Hydrochlorothiazide; Glucobay
Possible Afinitor side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-03
Patient: male
Reactions: General Physical Health Deterioration
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in male
Reported by a physician from Germany on 2012-03-29
Patient: male, weighing 61.0 kg (134.2 pounds)
Reactions: Pneumonia, General Physical Health Deterioration, Neoplasm Progression, Disorientation, Cachexia, Multi-Organ Failure, Hypokinesia, Neoplasm Malignant, Breath Sounds Abnormal, Sepsis, Oedema Peripheral, Dehydration, Breath Odour, Altered State of Consciousness, Oxygen Saturation Decreased
Adverse event resulted in: death
Drug(s) suspected as cause:
Afinitor
Dosage: 10 mg, daily
Administration route: Oral
Indication: Renal Cell Carcinoma
Start date: 2011-01-05
End date: 2011-02-18
Sterofundin
Dosage: 1.5 l, per day
Indication: Dehydration
Other drugs received by patient: TPN; Dexametason
Possible Afinitor side effects in male
Reported by a physician from Germany on 2012-03-26
Patient: male
Reactions: Weight Decreased, Neoplasm Malignant, General Physical Health Deterioration, Neoplasm Progression, Asthenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: 10 mg, unk
Administration route: Oral
Indication: Renal Cell Carcinoma
Start date: 2011-05-02
End date: 2011-10-24
Zometa
Dosage: 4 mg/5ml
Indication: Bone Disorder
Start date: 2010-11-22
Other drugs received by patient: Sunitinib Malate; Metoprolol Succinate; Calcium Carbonate; Amlodipine; Votrient; Vitamin D
Possible Afinitor side effects in male
Reported by a consumer/non-health professional from Colombia on 2012-03-23
Patient: male
Reactions: Death, General Physical Health Deterioration
Adverse event resulted in: death
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in 70 year old male
Reported by a physician from Spain on 2012-03-19
Patient: 70 year old male
Reactions: Confusional State, Metabolic Acidosis, General Physical Health Deterioration, Coma, Encephalopathy, Disorientation, Renal Failure Acute
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Afinitor
Other drugs received by patient: Aerosols; Enalapril; Somatuline Depot
Possible Afinitor side effects in male
Reported by a physician from Spain on 2012-03-15
Patient: male
Reactions: Encephalopathy, General Physical Health Deterioration
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in male
Reported by a physician from Spain on 2012-03-12
Patient: male
Reactions: General Physical Health Deterioration, Encephalopathy
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in 73 year old male
Reported by a physician from Israel on 2012-03-02
Patient: 73 year old male
Reactions: Dyspnoea, Blood Pressure Systolic Increased, General Physical Health Deterioration, Pyrexia, Cardiomyopathy, Renal Failure, Aspiration, Cyanosis, Cyanosis Central, Blood Creatinine Increased, Cardiac Failure Congestive, Infection
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Afinitor
Possible Afinitor side effects in male
Reported by a consumer/non-health professional from United States on 2012-03-01
Patient: male
Reactions: Lung Disorder, General Physical Health Deterioration, Fall, RIB Fracture
Adverse event resulted in: death
Drug(s) suspected as cause:
Afinitor
Indication: Benign Neoplasm of Islets of Langerhans
Afinitor
Dosage: 10 mg, qd
Administration route: Oral
Indication: Malignant Neoplasm of Islets of Langerhans
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