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Afinitor (Everolimus) - Fatigue - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Fatigue (196)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Afinitor (Everolimus) where reactions include fatigue. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 196   Next >>

Possible Afinitor side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-26

Patient: female

Reactions: Dyspnoea, Drug Ineffective, Pain, Localised Oedema, Neoplasm Progression, Cyst, Somnolence, Fatigue, Arthralgia, Neck Pain, Joint Swelling, Arthritis, Immobile, Mobility Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, (every day)
    Administration route: Oral
    Indication: Carcinoid Tumour
    Start date: 2011-08-01
    End date: 2012-02-23

Sandostatin LAR
    Dosage: 30 mg, qmo
    Indication: Carcinoid Tumour
    Start date: 2006-09-01

Other drugs received by patient: Dacarbazine



Possible Afinitor side effects in male

Reported by a physician from Canada on 2012-08-23

Patient: male, weighing 113.4 kg (249.4 pounds)

Reactions: Blood Cholesterol Abnormal, Diabetes Mellitus, Weight Increased, Abnormal Dreams, Malaise, Fatigue, Thinking Abnormal, Musculoskeletal Stiffness, Muscle Spasms, Blood Pressure Increased, Blood Cortisol Abnormal, Hormone Level Abnormal, Cushing's Syndrome, Psychotic Disorder, Blood Potassium Decreased, Neoplasm Malignant, Swelling, Feeling Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10mg every day
    Administration route: Oral
    Indication: Ectopic Acth Syndrome
    Start date: 2011-05-01

Sandostatin LAR
    Dosage: 30 mg every 2 weeks

Sandostatin LAR
    Dosage: 30 mg, qmo
    Indication: Ectopic Acth Syndrome
    Start date: 2010-11-30



Possible Afinitor side effects in female

Reported by a physician from Ireland on 2012-08-21

Patient: female, weighing 45.0 kg (99.0 pounds)

Reactions: Weight Decreased, Fatigue, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 5 mg, unk
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-02-04
    End date: 2011-05-30

Comparator Trastuzumab
    Dosage: 90 mg, weekly
    Indication: Breast Cancer Metastatic
    Start date: 2011-02-04

Paclitaxel
    Dosage: 90 mg, weekly
    Start date: 2011-02-04
    End date: 2011-05-27

Paclitaxel
    Dosage: 60 mg/m2
    Start date: 2011-03-18
    End date: 2011-04-15

Other drugs received by patient: Lipitor; Micardis; Pantoprazole; Acetaminophen; Pantoprazole; Valoid



Possible Afinitor side effects in female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-21

Patient: female

Reactions: Injection Site Mass, Contusion, Pneumonia, Nausea, Pain, Fall, Pallor, Myalgia, Malaise, Fatigue, Diarrhoea, Blood Potassium Decreased, Decreased Appetite, Lethargy

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, unk
    Administration route: Oral

Afinitor
    Dosage: 10 mg, every day
    Administration route: Oral
    Indication: Carcinoid Tumour

Sandostatin LAR
    Dosage: 80 mg, every four weeks

Sandostatin LAR
    Dosage: 80 mg, qmo
    Indication: Carcinoid Tumour
    Start date: 2008-04-28

Sandostatin LAR
    Dosage: 80 mg, once in a month
    Start date: 2008-04-28



Possible Afinitor side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-21

Patient: female

Reactions: Confusional State, Dyspnoea, Neoplasm Progression, Blood Glucose Decreased, Malaise, Fatigue, Neoplasm Malignant, Brain Oedema, Diabetic Coma, Hypersomnia, Lethargy, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Lipitor; Oral Antidiabetics; Antiobesity Preparations, Excl Diet Products; Beta Blocking Agents; Steroids NOS



Possible Afinitor side effects in female

Reported by a physician from United States on 2012-08-17

Patient: female

Reactions: Pain in Extremity, Disorientation, Rash, Somnolence, Convulsion, Paraesthesia, Burning Sensation, Fatigue, Arthralgia, Feeling Hot, Blood Cholesterol Increased, Dizziness, Asthenia, Feeling Abnormal, Lethargy

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Lamictal; Vitamins NOS; Depo-Provera; Calcium Supplements; Sodium Bicarbonate; Tegretol; Sabril; Keppra; Vitamin D; Klonopin; Prilosec; Topamax



Possible Afinitor side effects in female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-16

Patient: female

Reactions: Tumour Necrosis, Fatigue, Blood Bilirubin Abnormal, Oedema Peripheral, Bile Duct Cancer

Drug(s) suspected as cause:
Afinitor
    Dosage: 5 mg, everyday
    Administration route: Oral
    Indication: Neuroendocrine Tumour
    Start date: 2011-06-23

Sandostatin LAR
    Dosage: 30 mg, every four weeks
    Indication: Neuroendocrine Tumour
    Start date: 2011-04-20



Possible Afinitor side effects in male

Reported by a physician from Canada on 2012-08-16

Patient: male

Reactions: Blood Pressure Increased, Weight Decreased, Stomatitis, Rash Generalised, Somnolence, Rash Macular, Fatigue, Diarrhoea, Platelet Count Decreased, Heart Rate Irregular, Emotional Disorder, Depression, Blood Glucose Increased, Decreased Appetite

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Neuroendocrine Tumour
    Start date: 2011-04-11
    End date: 2011-05-02

Afinitor
    Dosage: 10 mg daily
    Administration route: Oral
    Start date: 2011-05-24

Sandostatin LAR
    Dosage: 30 mg every 4 weeks
    Indication: Neuroendocrine Tumour
    Start date: 2010-06-10



Possible Afinitor side effects in female

Reported by a physician from Canada on 2012-08-14

Patient: female

Reactions: Weight Decreased, Abdominal Pain, Pyrexia, Headache, Erythema, Abdominal Pain Upper, Injection Site Erythema, Fatigue, Dyspepsia, Abdominal Distension, Cough, Vomiting, Swelling Face, Abscess Oral, Acne, Hyperglycaemia, Secretion Discharge, Paraesthesia, Injection Site Pruritus, Diarrhoea, Oral Mucosal Erythema, Ocular Hyperaemia, Insomnia, Lacrimation Increased, Influenza Like Illness

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-07-01

Afinitor
    Dosage: 5 mg, unk
    Indication: Insulinoma
    Start date: 2011-10-28

Sandostatin LAR
    Dosage: 20 mg once a month
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-07-01

Sandostatin LAR
    Indication: Insulinoma

Other drugs received by patient: Codeine Syrup; Elavil



Possible Afinitor side effects in male

Reported by a physician from Japan on 2012-08-13

Patient: male, weighing 64.0 kg (140.8 pounds)

Reactions: Renal Failure, Fatigue, Tachycardia, Sepsis, Muscular Weakness, Depressed Level of Consciousness, Pyrexia, Anuria

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 5 mg, daily
    Administration route: Oral
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2012-04-16
    End date: 2012-07-20

Celecoxib
    Dosage: 100 mg, daily
    Start date: 2011-12-19
    End date: 2012-07-20

Zyrtec
    Dosage: 10 mg, daily
    Administration route: Oral
    Start date: 2012-05-07
    End date: 2012-07-20

Other drugs received by patient: Tamsulosin HCL; Famotidine; Daio-Kanzo-TO; Lantus; Sandostatin LAR; Novorapid; Antebate; Adona



Possible Afinitor side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-09

Patient: female

Reactions: Weight Decreased, Abdominal Pain, Pyrexia, Headache, Erythema, Abdominal Pain Upper, Injection Site Erythema, Fatigue, Dyspepsia, Abdominal Distension, Cough, Vomiting, Swelling Face, Abscess Oral, Acne, Hyperglycaemia, Secretion Discharge, Paraesthesia, Injection Site Pruritus, Oral Mucosal Erythema, Diarrhoea, Insomnia, Ocular Hyperaemia, Lacrimation Increased, Influenza Like Illness

Drug(s) suspected as cause:
Afinitor
    Dosage: 5 mg, unk
    Indication: Insulinoma
    Start date: 2011-10-28

Afinitor
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-07-01

Sandostatin LAR
    Dosage: 20 mg once a month
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-07-01

Sandostatin LAR
    Indication: Insulinoma

Other drugs received by patient: Codeine Syrup; Elavil



Possible Afinitor side effects in male

Reported by a consumer/non-health professional from Canada on 2012-08-08

Patient: male

Reactions: Weight Decreased, White Blood Cell Count Decreased, Jaundice, Impaired Work Ability, General Physical Health Deterioration, Neoplasm Progression, Device Occlusion, Hepatic Enzyme Increased, Liver Disorder, Abdominal Discomfort, Haemoglobin Decreased, Fatigue, Platelet Count Decreased, Neutrophil Count Decreased, Neuroendocrine Tumour

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, every other day (for a month)
    Administration route: Oral

Afinitor
    Dosage: 5 mg, unk
    Administration route: Oral
    Start date: 2011-10-27
    End date: 2012-04-23

Afinitor
    Dosage: 10 mg, every day
    Administration route: Oral
    Indication: Neuroendocrine Carcinoma Metastatic
    Start date: 2011-10-15

Sandostatin LAR
    Dosage: 30 mg, every 4 weeks
    Indication: Neuroendocrine Tumour
    Start date: 2011-07-14

Other drugs received by patient: Pancrease; Dexamethasone; Gabapentin; Pantoprazole Sodium



Possible Afinitor side effects in female

Reported by a physician from Canada on 2012-08-08

Patient: female

Reactions: Weight Decreased, Back Pain, Vomiting, Injection Site Pain, Hyperhidrosis, Fatigue, Metastases To Spine, Fluid Retention, Blood Pressure Diastolic Decreased, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor
    Administration route: Oral
    Indication: Carcinoid Tumour
    Start date: 2010-07-05

Sandostatin LAR
    Dosage: 30 mg, qmo

Sandostatin LAR
    Dosage: 30 mg once a month
    Indication: Carcinoid Tumour
    Start date: 2009-06-04
    End date: 2010-01-18

Sandostatin LAR
    Dosage: 20 mg every 4 weeks

Sandostatin LAR
    Dosage: 30 mg every 4 weeks

Sandostatin LAR
    Dosage: 30 mg, every four weeks
    End date: 2012-06-18

Other drugs received by patient: Morphine Sulfate; Chemotherapeutics; Radiotherapy



Possible Afinitor side effects in female

Reported by a physician from United States on 2012-08-08

Patient: female

Reactions: Weight Decreased, Central Nervous System Lesion, Headache, Pyrexia, Trigger Finger, Fatigue, DRY Mouth, Decreased Appetite, Oral Mucosal Blistering, Stomatitis, Nausea, Concomitant Disease Aggravated, Rash, Dysgeusia, Diarrhoea, Asthenia

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Ativan; Nexavar; Arimidex; Citalopram Hydrobromide; Metoprolol Tartrate; Imodium



Possible Afinitor side effects in female

Reported by a health professional (non-physician/pharmacist) from Israel on 2012-08-08

Patient: female, weighing 52.5 kg (115.5 pounds)

Reactions: Gastrointestinal Angiodysplasia Haemorrhagic, Fatigue, Anaemia, Angiodysplasia, Lymphocyte Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg/day
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-09
    End date: 2012-07-29

Letrozole
    Dosage: 2.5 mg/day
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-09
    End date: 2012-07-29

Other drugs received by patient: Zometa; Adrenalin IN OIL INJ; Nexium



Possible Afinitor side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-06

Patient: female

Reactions: Drug Ineffective, Neoplasm Progression, Abdominal Pain Upper, Death, Fatigue, Neoplasm Malignant, Sleep Disorder, Platelet Count Decreased, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Pancreatic Neuroendocrine Tumour Metastatic
    Start date: 2011-11-22
    End date: 2011-12-19

Afinitor
    Dosage: 5 mg, every day
    Administration route: Oral
    Start date: 2011-12-20
    End date: 2012-02-28

Afinitor
    Dosage: 10 mg every other day
    Administration route: Oral
    Start date: 2012-02-28
    End date: 2012-03-05

Afinitor
    Dosage: 05 mg every other day
    Administration route: Oral
    Start date: 2012-02-29
    End date: 2012-03-06



Possible Afinitor side effects in male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-01

Patient: male

Reactions: Blood Glucose Decreased, Fatigue, Pruritus, Blood Pressure Systolic Increased, Acne

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg every day
    Administration route: Oral
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2012-01-18

Sandostatin LAR
    Dosage: 20 mg, qmo
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-02-14



Possible Afinitor side effects in female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-01

Patient: female

Reactions: Weight Decreased, Abdominal Pain, Headache, Pyrexia, Erythema, Abdominal Pain Upper, Fatigue, Injection Site Erythema, Dyspepsia, Abdominal Distension, Cough, Vomiting, Swelling Face, Abscess Oral, Hyperglycaemia, Acne, Secretion Discharge, Injection Site Pruritus, Paraesthesia, Oral Mucosal Erythema, Diarrhoea, Insomnia, Ocular Hyperaemia, Lacrimation Increased, Influenza Like Illness

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-08-17

Afinitor
    Dosage: 05 mg, unk
    Start date: 2011-10-28

Sandostatin LAR
    Dosage: 20 mg once a month
    Indication: Pancreatic Neuroendocrine Tumour
    Start date: 2011-08-08

Other drugs received by patient: Elavil; Codeine Syrup



Possible Afinitor side effects in female

Reported by a physician from Australia on 2012-08-01

Patient: female

Reactions: Abdominal Pain, Fatigue, Vomiting, Nausea, Toxicity To Various Agents

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: unk
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2011-05-03

Sunitinib Malate
    Dosage: 50 mg, unk
    Indication: Renal Cell Carcinoma
    Start date: 2011-03-22
    End date: 2011-04-08

Sunitinib Malate
    Dosage: 37.5 mg, unk
    Start date: 2011-04-14

Other drugs received by patient: Kalma; Atacand



Possible Afinitor side effects in male

Reported by a physician from Portugal on 2012-08-01

Patient: male

Reactions: Dyspnoea, Skin Exfoliation, Hepatic Lesion, Myalgia, Fatigue, Respiratory Failure, Pleural Effusion, Azotaemia, Asthenia, Pneumonitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor



Possible Afinitor side effects in male

Reported by a physician from Canada on 2012-08-01

Patient: male

Reactions: Abdominal Pain, Pallor, Hepatic Neoplasm, Faecal Volume Increased, Poor Quality Sleep, Fatigue, Gastrointestinal Neoplasm, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg every day
    Administration route: Oral
    Indication: Neuroendocrine Tumour
    Start date: 2011-04-18

Sandostatin LAR
    Dosage: 30 mg, biw
    Indication: Neuroendocrine Tumour
    Start date: 2010-10-25



Possible Afinitor side effects in male

Reported by a physician from Japan on 2012-07-31

Patient: male

Reactions: Respiratory Disorder, Dyspnoea, Blood Lactate Dehydrogenase Increased, Neoplasm Progression, Pyrexia, Appetite Disorder, Fatigue, Malaise, Neoplasm Malignant, Interstitial Lung Disease, C-Reactive Protein Increased, Cough

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Allopurinol; Hachiazule



Possible Afinitor side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-30

Patient: female

Reactions: Pain in Extremity, Rash, Disorientation, Somnolence, Convulsion, Burning Sensation, Fatigue, Arthralgia, Feeling Hot, Dizziness, Blood Cholesterol Increased, Feeling Abnormal, Asthenia, Lethargy

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Vitamins NOS; Lamictal; Calcium Supplements; Depo-Provera; Tegretol; Klonopin; Keppra; Vitamin D; Prilosec; Sodium Bicarbonate; Topamax; Sabril



Possible Afinitor side effects in female

Reported by a physician from Canada on 2012-07-24

Patient: female

Reactions: Injection Site Mass, Contusion, Pneumonia, Nausea, Pain, Pallor, Fall, Myalgia, Fatigue, Malaise, Diarrhoea, Blood Potassium Decreased, Lethargy

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, every day
    Administration route: Oral
    Indication: Carcinoid Tumour

Sandostatin LAR
    Dosage: 80 mg, qmo
    Indication: Carcinoid Tumour
    Start date: 2008-04-28

Sandostatin LAR
    Dosage: 80 mg, every four weeks



Possible Afinitor side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-24

Patient: female

Reactions: Mental Impairment, Fatigue, Angiomyolipoma, Decreased Appetite

Drug(s) suspected as cause:
Afinitor
    Dosage: 7.5 mg, daily
    Administration route: Oral

Afinitor
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Tuberous Sclerosis
    Start date: 2012-05-14
    End date: 2012-06-25

Other drugs received by patient: Ambien; Phenobarbital TAB; Simvastatin; Lorazepam; Levothyroxine Sodium; Prozac; Albuterol; Lisinopril



Possible Afinitor side effects in male

Reported by a physician from Canada on 2012-07-19

Patient: male

Reactions: Weight Decreased, Blood Pressure Increased, Stomatitis, Rash Generalised, Somnolence, Rash Macular, Fatigue, Diarrhoea, Platelet Count Decreased, Emotional Disorder, Depression, Decreased Appetite, Blood Glucose Increased

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg daily
    Administration route: Oral
    Start date: 2011-05-24

Afinitor
    Dosage: 10 mg, unk
    Administration route: Oral
    Indication: Neuroendocrine Tumour
    Start date: 2011-04-11
    End date: 2011-05-02

Sandostatin LAR
    Dosage: 30 mg every 4 weeks
    Indication: Neuroendocrine Tumour
    Start date: 2010-06-10



Possible Afinitor side effects in male

Reported by a physician from Canada on 2012-07-18

Patient: male, weighing 54.0 kg (118.8 pounds)

Reactions: Weight Increased, Death, Malaise, Fatigue, Pain, Underdose, Blood Creatinine Increased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 5 mg, qd
    Administration route: Oral
    Indication: Small Intestine Carcinoma
    Start date: 2011-08-04
    End date: 2011-12-02

Sandostatin LAR
    Dosage: 40mg every 3 weeks
    Indication: Small Intestine Carcinoma
    Start date: 2009-03-02



Possible Afinitor side effects in female

Reported by a consumer/non-health professional from Canada on 2012-07-17

Patient: female

Reactions: Dyspnoea, Drug Ineffective, Pain, Localised Oedema, Neoplasm Progression, Cyst, Somnolence, Fatigue, Joint Swelling, Neck Pain, Arthralgia, Arthritis, Mobility Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 10 mg, (every day)
    Administration route: Oral
    Indication: Carcinoid Tumour
    Start date: 2011-08-01
    End date: 2012-02-23

Sandostatin LAR
    Dosage: 30 mg, qmo
    Indication: Carcinoid Tumour
    Start date: 2006-09-01

Other drugs received by patient: Dacarbazine



Possible Afinitor side effects in female

Reported by a physician from United States on 2012-07-13

Patient: female

Reactions: Mental Impairment, Fatigue, Angiomyolipoma, Decreased Appetite

Drug(s) suspected as cause:
Afinitor

Other drugs received by patient: Phenobarbital; Albuterol; Lorazepam; Prozac; Levothyroxine Sodium; Lisinopril; Simvastatin; Ambien



Possible Afinitor side effects in male

Reported by a consumer/non-health professional from Canada on 2012-07-13

Patient: male

Reactions: Jaundice, Weight Decreased, Blood Bilirubin Increased, White Blood Cell Count Decreased, Neoplasm Progression, Hepatic Enzyme Increased, Liver Disorder, Haemoglobin Decreased, Abdominal Discomfort, Fatigue, Neoplasm Malignant, Platelet Count Decreased, Neutrophil Count Decreased

Drug(s) suspected as cause:
Afinitor
    Dosage: 5 mg, unk
    Administration route: Oral
    Start date: 2011-10-27
    End date: 2012-04-23

Afinitor
    Dosage: 10 mg, every day
    Administration route: Oral
    Indication: Neuroendocrine Carcinoma Metastatic
    Start date: 2011-10-15

Afinitor
    Dosage: 10 mg, every other day (for a month)
    Administration route: Oral

Sandostatin LAR
    Dosage: 30 mg, every 4 weeks
    Indication: Neuroendocrine Tumour
    Start date: 2011-07-14

Other drugs received by patient: Gabapentin; Pancrease; Pantoprazole Sodium; Dexamethasone



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