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Activase (Alteplase) - Hypertension - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Hypertension (10)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Activase (Alteplase) where reactions include hypertension. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Activase side effects in female

Reported by a physician from United States on 2012-08-15

Patient: female

Reactions: Hypertension

Drug(s) suspected as cause:
Activase
    Indication: Acute Myocardial Infarction

Activase
    Dosage: 50 mg/hour for 30 min

Activase
    Dosage: 35 mg/hour for next 60 min

Other drugs received by patient: Morphine Sulfate; Heparin; Heparin; NTG Infusion; Aspirin; Pepcid



Possible Activase side effects in 46 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-14

Patient: 46 year old male

Reactions: Hyperkalaemia, Chest Pain, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Activase



Possible Activase side effects in 50 year old male

Reported by a consumer/non-health professional from United States on 2012-08-13

Patient: 50 year old male

Reactions: Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Activase

Other drugs received by patient: Captopril



Possible Activase side effects in 46 year old male

Reported by a pharmacist from United States on 2012-08-06

Patient: 46 year old male

Reactions: Chest Pain, Hypertension, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Activase



Possible Activase side effects in male

Reported by a physician from Germany on 2012-05-18

Patient: male, weighing 96.0 kg (211.2 pounds)

Reactions: Chest Pain, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Activase

Other drugs received by patient: Levothyroxine Sodium; Apidra; Lantus; Allobeta; Metoprolol Tartrate and Hydrochlorothiazide; Torsemide; Aspirin; Fluvastatin; Ismn; Olmesartan Medoxomil



Possible Activase side effects in 25 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-04-05

Patient: 25 year old female

Reactions: Electrocardiogram QT Prolonged, Abdominal Pain, Phaeochromocytoma, Haemorrhage, Tachycardia, Pulmonary Embolism, Pulmonary Congestion, Chest Pain, Pleural Effusion, Hypoxia, Arteriosclerosis, White Blood Cell Count Increased, Vomiting, Dyspnoea, Metabolic Acidosis, Neutrophil Count Increased, Anxiety, Haemoglobin Decreased, Electrocardiogram ST Segment Elevation, Cardiac Arrest, Hypertension, Pulseless Electrical Activity

Adverse event resulted in: death

Drug(s) suspected as cause:
Propranolol
    Dosage: 20 mg, unk
    Administration route: Oral
    Indication: Anxiety
    Start date: 2011-10-01
    End date: 2011-10-01

Activase
    Dosage: 50 mg, bid
    Indication: Pulmonary Embolism
    Start date: 2011-10-01
    End date: 2011-10-01

Other drugs received by patient: Midazolam; Suxamethonium; Morphine



Possible Activase side effects in 25 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-03-29

Patient: 25 year old female

Reactions: Electrocardiogram QT Prolonged, Abdominal Pain, Phaeochromocytoma, Haemorrhage, Tachycardia, Pulmonary Embolism, Chest Pain, Pulmonary Congestion, Pleural Effusion, Hypoxia, Arteriosclerosis, White Blood Cell Count Increased, Vomiting, Neutrophil Count Increased, Dyspnoea, Metabolic Acidosis, Haemoglobin Decreased, Anxiety, Electrocardiogram ST Segment Elevation, Hypertension, Cardiac Arrest, Pulseless Electrical Activity

Adverse event resulted in: death

Drug(s) suspected as cause:
Activase
    Dosage: 50 mg, bid
    Indication: Pulmonary Embolism
    Start date: 2011-10-01

Propranolol
    Dosage: 20 mg, unk
    Administration route: Oral
    Indication: Anxiety
    Start date: 2011-10-01

Other drugs received by patient: Morphine; Midazolam; Suxamethonium



Possible Activase side effects in 66 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-01-02

Patient: 66 year old male, weighing 84.5 kg (185.9 pounds)

Reactions: Tachycardia, Rash, Neurological Symptom, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Activase

Other drugs received by patient: Meloxicam



Possible Activase side effects in 50 year old male

Reported by a physician from Russian Federation on 2011-11-04

Patient: 50 year old male, weighing 80.0 kg (176.0 pounds)

Reactions: Tachycardia, Tonic Convulsion, Hypertension

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Activase



Possible Activase side effects in 50 year old male

Reported by a physician from Russian Federation on 2011-11-01

Patient: 50 year old male, weighing 80.0 kg (176.0 pounds)

Reactions: Tachycardia, Tonic Convulsion, Hypertension

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Activase

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