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Abraxane (Paclitaxel) - White Blood Cell Count Decreased - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with White Blood Cell Count Decreased (21)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Abraxane (Paclitaxel) where reactions include white blood cell count decreased. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: female, weighing 64.9 kg (142.8 pounds)

Reactions: Abdominal Pain, White Blood Cell Count Decreased, Vomiting, Gastrointestinal Haemorrhage, Nausea, Hyponatraemia, Hypokalaemia, Haemoglobin Decreased, Diarrhoea, Dehydration, Hypocalcaemia, Neutrophil Count Decreased, Blood Creatinine Increased, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: 139 milligram
    Start date: 2012-07-18

Abraxane
    Dosage: 177 milligram
    Start date: 2012-07-18
    End date: 2012-07-25

Herceptin
    Dosage: 139 milligram
    Indication: Breast Cancer
    Start date: 2012-06-13

Abraxane
    Dosage: 80 microgram/sq. meter
    Start date: 2012-08-01

Carboplatin
    Dosage: 675 milligram
    Indication: Breast Cancer
    Start date: 2012-06-13

Carboplatin
    Dosage: 675 milligram
    Start date: 2012-07-18

Abraxane
    Dosage: 177 milligram
    Indication: Breast Cancer
    Start date: 2012-06-13

Other drugs received by patient: Dexamethasone; Gabapentin; Ativan; Motrin; Ativan; Vicodin; Ativan; Ativan



Possible Abraxane side effects in 43 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-03

Patient: 43 year old female, weighing 64.9 kg (142.8 pounds)

Reactions: Abdominal Pain, White Blood Cell Count Decreased, Vomiting, Nausea, Gastrointestinal Toxicity, Haemorrhoids, Haematemesis, Haemoglobin Decreased, Blood Potassium Decreased, NO Therapeutic Response, Diarrhoea Haemorrhagic, Dehydration, Clostridial Infection, Epistaxis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: 139 mg
    Indication: Breast Cancer

Carboplatin
    Dosage: 675 mg
    Indication: Breast Cancer

Abraxane
    Dosage: 177 mg
    Indication: Breast Cancer

Other drugs received by patient: Dexamethasone; Ativan; Lomotil; Gabapentin; Ondansetron HCL; Vicodin; Pantoprazole



Possible Abraxane side effects in female

Reported by a physician from United States on 2012-07-19

Patient: female, weighing 57.9 kg (127.4 pounds)

Reactions: White Blood Cell Count Decreased, Diarrhoea, Otitis Externa, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: 120 milligram
    Start date: 2012-06-05

Herceptin
    Dosage: 120 milligram
    Start date: 2012-06-12

Carboplatin
    Dosage: 720 milligram
    Indication: Breast Cancer
    Start date: 2012-04-17
    End date: 2012-06-26

Abraxane
    Dosage: 128 milligram
    Indication: Breast Cancer
    Start date: 2012-04-17
    End date: 2012-06-26

Abraxane
    Dosage: 118 milligram

Herceptin
    Dosage: 2 milligram
    Start date: 2012-05-29

Other drugs received by patient: Ciprofloxacin; Zofran; Neurontin; Protonix; Colace; Lovenox; Neurontin; Neupogen; Ciprofloxacin; Atenolol; Zolpidem; Magnesium Sulfate; Imodium; K-TAB; Vicodin; Zosyn; Zofran; Vancomycin; Levaquin; Morphine Sulfate; Ciprofloxacin HCL; Augmentin '500'; Acyclovir



Possible Abraxane side effects in 51 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-05-30

Patient: 51 year old female, weighing 57.0 kg (125.4 pounds)

Reactions: White Blood Cell Count Decreased, Stomatitis

Drug(s) suspected as cause:
Abraxane
    Dosage: 260 milligram/sq. meter
    Start date: 2012-01-19

Abraxane
    Dosage: 220 milligram/sq. meter
    Start date: 2012-02-22



Possible Abraxane side effects in female

Reported by a physician from United States on 2012-05-23

Patient: female, weighing 112.0 kg (246.4 pounds)

Reactions: White Blood Cell Count Decreased, Cellulitis, Pain in Extremity, Urinary Tract Infection, Constipation, International Normalised Ratio, Hypokalaemia, Haemoglobin Decreased, Hypoalbuminaemia, Neutropenia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 900 milligram
    Indication: Breast Cancer
    Start date: 2012-03-02

Herceptin
    Dosage: 224 milligram
    Start date: 2012-04-20
    End date: 2012-04-27

Abraxane
    Dosage: 213 milligram
    Start date: 2012-04-20
    End date: 2012-04-27

Herceptin
    Dosage: 224 milligram
    Indication: Breast Cancer
    Start date: 2012-03-02

Carboplatin
    Dosage: 900 milligram
    Start date: 2012-04-20
    End date: 2012-04-27

Abraxane
    Dosage: 213 milligram
    Indication: Breast Cancer
    Start date: 2012-03-02

Other drugs received by patient: Prochlorperazine; Ondansetron HCL; Ondansetron HCL; Prochlorperazine; Gentamicin; Miralax; Dexamethasone; Ambien; Potassium Chloride; Coumadin; Cozaar; Potassium Chloride; Zosyn; Vancomycin; Coumadin



Possible Abraxane side effects in 54 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-07

Patient: 54 year old female, weighing 68.1 kg (149.7 pounds)

Reactions: White Blood Cell Count Decreased, Anaemia, Platelet Count Decreased, Febrile Neutropenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 80 milligram/sq. meter
    Start date: 2011-10-13

Carboplatin
    Dosage: 6 dosage forms
    Indication: Breast Cancer
    Start date: 2011-08-11

Doxorubicin HCL
    Dosage: 60 milligram/sq. meter
    Indication: Breast Cancer
    Start date: 2011-11-10

Cyclophosphamide
    Dosage: 600 milligram/sq. meter
    Indication: Breast Cancer
    Start date: 2011-11-10

Abraxane
    Dosage: 80 milligram/sq. meter
    Indication: Breast Cancer
    Start date: 2011-08-11
    End date: 2011-10-06

Neulasta
    Indication: Chemotherapy

Bevacizumab
    Dosage: 10 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-08-11



Possible Abraxane side effects in male

Reported by a consumer/non-health professional from United States on 2012-03-07

Patient: male

Reactions: White Blood Cell Count Decreased, Chest Discomfort, RED Blood Cell Count Decreased, Alopecia, Platelet Count Decreased, Hypoaesthesia

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: Aranesp



Possible Abraxane side effects in 44 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-01

Patient: 44 year old female, weighing 119.6 kg (263.1 pounds)

Reactions: White Blood Cell Count Decreased, Diarrhoea, Lymphatic Disorder, Anaemia, Platelet Count Decreased, Febrile Neutropenia, Cardiac Disorder

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Dosage: 10 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Doxorubicin HCL
    Dosage: 10 milligram/sq. meter
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 600 milligram/sq. meter
    Indication: Breast Cancer
    Start date: 2011-03-24

Abraxane
    Dosage: 80 milligram/sq. meter
    Indication: Breast Cancer
    Start date: 2011-03-24

Neulasta
    Dosage: 6 milligram
    End date: 2011-08-25

Other drugs received by patient: Metoprolol Tartrate; Famotidine; Guaifenesin; Zolpidem; Cefepime; Fluconazole; Prochlorperazine; Bacitracin; Whole Blood; Benzonatate; Acetaminophen



Possible Abraxane side effects in 44 year old female

Reported by a physician from United States on 2012-01-30

Patient: 44 year old female, weighing 119.6 kg (263.1 pounds)

Reactions: White Blood Cell Count Decreased, Type 2 Diabetes Mellitus, Lymphatic Disorder, Anaemia, Pancytopenia, Febrile Neutropenia, Cardiac Disorder, Diarrhoea, Platelet Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 10 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Neulasta
    Dosage: 6 milligram
    Indication: Breast Cancer
    End date: 2011-08-25

Abraxane
    Dosage: 80 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Bevacizumab
    Dosage: 10 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 600 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Other drugs received by patient: Ambien; Pepcid; Mucinex; Tessalon; Toprol-XL; Bacitracin; Prochlorperazine; Armodafinil; Acetaminophen; Cefepime



Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-01-26

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: White Blood Cell Count Decreased, Neutrophil Count Decreased

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: Sinseron; Magmitt; Posterisan



Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-21

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: White Blood Cell Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: Posterisan; Sinseron; Magmitt



Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-14

Patient: female, weighing 53.0 kg (116.6 pounds)

Reactions: White Blood Cell Count Decreased, Neutrophil Count Decreased

Drug(s) suspected as cause:
Abraxane
    Dosage: 155 milligram
    Start date: 2011-06-03

Abraxane
    Dosage: 240 milligram
    Start date: 2011-03-18

Abraxane
    Dosage: 380 milligram
    Indication: Breast Cancer Metastatic
    Start date: 2011-01-21
    End date: 2011-01-21

Abraxane
    Start date: 2011-07-01

Abraxane
    Dosage: 190 milligram
    Start date: 2011-05-06

Abraxane
    Dosage: 300 milligram
    Start date: 2011-02-18
    End date: 2011-02-18

Other drugs received by patient: Aloxi; Famotidine; Decadron



Possible Abraxane side effects in 44 year old female

Reported by a physician from United States on 2011-12-13

Patient: 44 year old female, weighing 119.6 kg (263.1 pounds)

Reactions: White Blood Cell Count Decreased, Diarrhoea, Lymphatic Disorder, Anaemia, Febrile Neutropenia, Platelet Count Decreased, Cardiac Disorder

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Dosage: 10 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 600 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Doxorubicin HCL
    Dosage: 10 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Abraxane
    Dosage: 80 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Pegfilgrastim
    Dosage: 6 milligram
    Indication: Breast Cancer
    End date: 2011-08-25

Other drugs received by patient: Cefepime; Pepcid; Diflucan; Bacitracin; Mucinex; Tessalon; Ambien; Toprol-XL; Prochlorperazine; Acetaminophen



Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-06

Patient: female, weighing 44.0 kg (96.8 pounds)

Reactions: White Blood Cell Count Decreased, C-Reactive Protein Increased, Neutrophil Count Decreased

Drug(s) suspected as cause:
Abraxane
    Dosage: 308 milligram
    Start date: 2010-12-01

Abraxane
    Dosage: 308 milligram
    Start date: 2011-01-04

Abraxane
    Dosage: 308 milligram
    Indication: Breast Cancer Metastatic
    Start date: 2010-10-12
    End date: 2010-10-12

Abraxane
    Dosage: 364 milligram
    Start date: 2011-01-27

Abraxane
    Dosage: 308 milligram
    Start date: 2010-11-02
    End date: 2010-11-02

Abraxane
    Dosage: 308 milligram
    Start date: 2010-11-25
    End date: 2010-11-25

Other drugs received by patient: Gran; Gran; Sefirom; Cyclophosphamide; Leuprolide Acetate; Fluorouracil; Epirubicin Hydrochloride



Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-06

Patient: female, weighing 70.0 kg (154.0 pounds)

Reactions: White Blood Cell Count Decreased, Stomatitis, Febrile Neutropenia, Blood Albumin Decreased, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 450 milligram
    Indication: Breast Cancer Metastatic
    Start date: 2011-02-01
    End date: 2011-02-01

Abraxane
    Dosage: 300 milligram
    Start date: 2011-02-28
    End date: 2011-02-28

Other drugs received by patient: Fluid; Loxonin; Maxipime; Gran; Herceptin; Levofloxacin



Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-06

Patient: female, weighing 40.0 kg (88.0 pounds)

Reactions: Haemoglobin Decreased, White Blood Cell Count Decreased, C-Reactive Protein Increased, Sepsis, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Abraxane
    Dosage: 350 milligram
    Start date: 2010-10-15
    End date: 2010-10-15

Abraxane
    Dosage: 280 milligram
    Start date: 2010-11-19
    End date: 2010-11-19

Other drugs received by patient: Meropenem; Polygam S / D; Herceptin; Tykerb



Possible Abraxane side effects in 44 year old female

Reported by a physician from United States on 2011-11-29

Patient: 44 year old female, weighing 119.6 kg (263.1 pounds)

Reactions: White Blood Cell Count Decreased, Diarrhoea, Lymphatic Disorder, Anaemia, Platelet Count Decreased, Febrile Neutropenia, Cardiac Disorder

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 10 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Pegfilgrastim
    Dosage: 6 milligram
    Indication: Breast Cancer
    End date: 2011-08-25

Bevacizumab
    Dosage: 10 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Abraxane
    Dosage: 80 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 600 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Other drugs received by patient: Cefepime; Prochlorperazine; Diflucan; Bacitracin; Mucinex; Pepcid; Tessalon; Acetaminophen; Ambien; Toprol-XL



Possible Abraxane side effects in 44 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-28

Patient: 44 year old female, weighing 119.6 kg (263.1 pounds)

Reactions: White Blood Cell Count Decreased, Anaemia, Febrile Neutropenia, Platelet Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 10 milligram/sq. meter
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 600 milligram/sq. meter
    Indication: Breast Cancer
    Start date: 2011-03-24

Bevacizumab
    Dosage: 10 milligram/kilogram
    Indication: Breast Cancer
    Start date: 2011-03-24

Abraxane
    Dosage: 80 milligram/sq. meter
    Indication: Breast Cancer
    Start date: 2011-03-24

Pegfilgrastim
    Dosage: 6 milligram
    End date: 2011-08-25

Other drugs received by patient: Benzonatate; Guaifenesin; Zolpidem; Cefepime; Famotidine; Prochlorperazine; Metoprolol Tartrate; Bacitracin; Fluconazole; Acetaminophen; Whole Blood



Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-11-07

Patient: female, weighing 70.0 kg (154.0 pounds)

Reactions: Blood Alkaline Phosphatase Increased, White Blood Cell Count Decreased, Malaise, Nausea, Gamma-Glutamyltransferase Increased, C-Reactive Protein Increased, Pleural Effusion, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 390 milligram
    Indication: Breast Cancer Metastatic
    Start date: 2010-10-29
    End date: 2010-10-29

Abraxane
    Dosage: 380 milligram
    Start date: 2010-12-10

Abraxane
    Dosage: 316 milligram
    Start date: 2011-01-14

Abraxane
    Dosage: 316-387mg
    Start date: 2010-11-19
    End date: 2011-01-14

Other drugs received by patient: Rabeprazole Sodium; Maxipime; MS Contin; Whole Blood; Metoclopramide; Loxoprofen; Teprenone; Neutrogin; Furosemide; Emend; Amoban; Fudosteine



Possible Abraxane side effects in 63 year old female

Reported by a physician from United States on 2011-10-11

Patient: 63 year old female, weighing 89.2 kg (196.2 pounds)

Reactions: White Blood Cell Count Decreased, Dyspnoea, Anaemia, Muscular Weakness, Myalgia, Fatigue, Renal Failure, Diarrhoea, Proteinuria, Platelet Count Decreased, Hypocalcaemia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 232 milligram
    Start date: 2010-03-04

Gemcitabine Hydrochloride
    Dosage: 1860 milligram
    Start date: 2010-03-04

Gemcitabine Hydrochloride
    Dosage: 1860 milligram
    Start date: 2010-11-11
    End date: 2010-11-18

Abraxane
    Dosage: 232 milligram
    Start date: 2010-11-11
    End date: 2010-11-18

Bevacizumab
    Dosage: 1368 milligram
    Start date: 2010-03-04
    End date: 2010-10-21



Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-07

Patient: female, weighing 70.0 kg (154.0 pounds)

Reactions: White Blood Cell Count Decreased, Stomatitis, Febrile Neutropenia, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: Levofloxacin; Loxonin; Herceptin; Gran

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