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Abraxane (Paclitaxel) - Neutropenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Neutropenia (30)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Abraxane (Paclitaxel) where reactions include neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 30   Next >>

Possible Abraxane side effects in female

Reported by a physician from United States on 2012-08-27

Patient: female

Reactions: Neutropenia, Septic Shock, Renal Failure Acute, Leukopenia

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Abraxane
    Dosage: 125 milligram/sq. meter
    Start date: 2012-03-28

Gemcitabine Hydrochloride
    Dosage: 1000 milligram/sq. meter
    Start date: 2012-03-28

Abraxane
    Dosage: 125 milligram/sq. meter
    Start date: 2012-04-04
    End date: 2012-04-10

Gemcitabine Hydrochloride
    Dosage: 1000 milligram/sq. meter
    Start date: 2012-04-04
    End date: 2012-04-10



Possible Abraxane side effects in 48 year old female

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-13

Patient: 48 year old female, weighing 64.0 kg (140.8 pounds)

Reactions: Stomatitis, Vomiting, Nausea, Anaemia, Bone Pain, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Neurotoxicity, Neuropathy Peripheral, Diarrhoea, Cardiotoxicity, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Abraxane



Possible Abraxane side effects in female

Reported by a physician from Germany on 2012-08-07

Patient: female, weighing 67.0 kg (147.4 pounds)

Reactions: Breast Cancer Metastatic, Cerebral Disorder, Anaemia, General Physical Health Deterioration, Neutropenia, Asthenia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Abraxane
    Start date: 2011-06-27
    End date: 2011-06-27

Abraxane
    Start date: 2011-06-06
    End date: 2011-06-06

Abraxane
    Start date: 2011-07-18
    End date: 2011-07-18

Other drugs received by patient: Antiemetic Drugs; Antiemetic Drugs; Antiemetic Drugs



Possible Abraxane side effects in female

Reported by a lawyer from United States on 2012-08-07

Patient: female, weighing 68.0 kg (149.7 pounds)

Reactions: Abdominal Pain, Osteomyelitis, Pyrexia, Gingival Abscess, Cyst, Loss of Consciousness, Abdominal Discomfort, Dyspepsia, Simplex Virus Test Positive, Multiple Injuries, Unevaluable Event, Immunosuppression, Back Pain, Dysphagia, Coronary Artery Disease, Nasal Congestion, Renal Cyst, Cardiomyopathy, Dysphonia, Insomnia, Ocular Icterus, Neutropenia, Vocal Cord Polyp, Jaundice, Pain, Chills, Hepatic Lesion, Haemorrhoidal Haemorrhage, Myalgia, Bone Loss, Fatigue, Anhedonia, Left Ventricular Dysfunction, Neck Pain, Pleural Effusion, Intervertebral Disc Degeneration, Decreased Appetite, Vulvovaginal Mycotic Infection, Bone Lesion, Rash, Dysgeusia, Anxiety, Agranulocytosis, Osteonecrosis of JAW, Cardiac Failure, Oral Disorder, Spinal Osteoarthritis, Asthenia, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zometa
    Dosage: unk ukn, every 4 weeks
    Start date: 2006-04-01
    End date: 2007-06-01

Abraxane
    Dosage: 170 mg, unk

Other drugs received by patient: Xanax; Chemotherapeutics; Restoril; Oxycodone HCL; Humira; Neupogen; Acyclovir; Coumadin; Percocet; Fentanyl; Decadron; Ativan; Faslodex; Femara; Wellbutrin; Radiation; Compazine; Taxotere; Zofran; Aromasin; Neulasta



Possible Abraxane side effects in 59 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-13

Patient: 59 year old female, weighing 58.9 kg (129.6 pounds)

Reactions: Otitis Externa, Skin Hyperpigmentation, Hypoacusis, Neuropathy Peripheral, Diarrhoea, Ear Pain, Otitis Media, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 128 mg iv, 118 mg iv
    Indication: Chemotherapy
    Start date: 2012-04-17
    End date: 2012-06-26

Carboplatin
    Dosage: 720 mg
    Indication: Chemotherapy
    Start date: 2012-04-17
    End date: 2012-06-26

Other drugs received by patient: Zofren 8 MG; Atenolol; Neurontin



Possible Abraxane side effects in

Reported by a physician from United States on 2012-06-15

Patient:

Reactions: Hypotension, Transaminases Increased, Optic Neuropathy, Oesophagitis, Diarrhoea, Sepsis, Dehydration, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Abraxane

Erlotinib Hydrochloride

Gemcitabine



Possible Abraxane side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-14

Patient:

Reactions: Stomatitis, Pancreatic Carcinoma, Nausea, Anaemia, Neuropathy Peripheral, Renal Failure, Fatigue, Diarrhoea, Neutropenia, Thrombocytopenia, Hypertension

Drug(s) suspected as cause:
Bevacizumab
    Dosage: 5 milligram/kilogram

Abraxane
    Dosage: 100 milligram/sq. meter

Fluorouracil
    Dosage: 180 milligram/sq. meter

Oxaliplatin
    Dosage: 75 milligram/sq. meter

Leucovorin Calcium
    Dosage: 20 milligram/sq. meter



Possible Abraxane side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-14

Patient:

Reactions: Tinnitus, Transaminases, Anaemia, Lymphopenia, Hyponatraemia, Rash, Neuropathy Peripheral, Diarrhoea, Neutropenia, Thrombocytopenia, Leukopenia, Infection

Drug(s) suspected as cause:
Abraxane



Possible Abraxane side effects in 56 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-11

Patient: 56 year old female

Reactions: Incontinence, Anaemia, Urosepsis, Hydrocephalus, Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 100 milligram/sq. meter
    Indication: Breast Cancer Metastatic
    Start date: 2007-01-01
    End date: 2007-01-01

Carboplatin
    Dosage: auc6, 1hour infusion on day 1
    Indication: Breast Cancer Metastatic
    Start date: 2007-01-01

Carboplatin
    Dosage: auc2
    Start date: 2007-01-01
    End date: 2007-01-01



Possible Abraxane side effects in 56 year old

Reported by a individual with unspecified qualification from United States on 2012-06-11

Patient: 56 year old

Reactions: Anaemia, Urosepsis, Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Abraxane

Abraxane
    Dosage: 100 milligram/sq. meter
    Start date: 2007-01-01

Carboplatin
    Start date: 2007-01-01

Carboplatin



Possible Abraxane side effects in female

Reported by a physician from Spain on 2012-06-07

Patient: female

Reactions: Vomiting, Nausea, Anaemia, Death, Fatigue, Diarrhoea, Pancreatic Carcinoma Metastatic, Alopecia, Neutropenia, Thrombocytopenia, Asthenia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: Transfusion



Possible Abraxane side effects in 56 year old

Reported by a physician from United States on 2012-06-05

Patient: 56 year old

Reactions: Anaemia, Urosepsis, Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin

Abraxane
    Dosage: 100 milligram/sq. meter
    Start date: 2007-01-01

Carboplatin
    Start date: 2007-01-01

Abraxane



Possible Abraxane side effects in female

Reported by a physician from Spain on 2012-06-04

Patient: female

Reactions: Death, Fatigue, Vomiting, Nausea, Anaemia, Neutropenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: Neupogen



Possible Abraxane side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-05-31

Patient: 65 year old female, weighing 70.0 kg (154.0 pounds)

Reactions: Stomatitis, Urinary Tract Infection, Neoplasm Progression, Dysplasia, Neutropenia, Pharyngitis

Adverse event resulted in: death

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: Opiate; Dexamethasone; Hydromorphon; Granisetron Hydrochloride; Dipyrone TAB; Zometa; Arlevert



Possible Abraxane side effects in female

Reported by a physician from United States on 2012-05-23

Patient: female, weighing 112.0 kg (246.4 pounds)

Reactions: White Blood Cell Count Decreased, Cellulitis, Pain in Extremity, Urinary Tract Infection, Constipation, International Normalised Ratio, Hypokalaemia, Haemoglobin Decreased, Hypoalbuminaemia, Neutropenia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 900 milligram
    Indication: Breast Cancer
    Start date: 2012-03-02

Herceptin
    Dosage: 224 milligram
    Start date: 2012-04-20
    End date: 2012-04-27

Abraxane
    Dosage: 213 milligram
    Start date: 2012-04-20
    End date: 2012-04-27

Herceptin
    Dosage: 224 milligram
    Indication: Breast Cancer
    Start date: 2012-03-02

Carboplatin
    Dosage: 900 milligram
    Start date: 2012-04-20
    End date: 2012-04-27

Abraxane
    Dosage: 213 milligram
    Indication: Breast Cancer
    Start date: 2012-03-02

Other drugs received by patient: Prochlorperazine; Ondansetron HCL; Ondansetron HCL; Prochlorperazine; Gentamicin; Miralax; Dexamethasone; Ambien; Potassium Chloride; Coumadin; Cozaar; Potassium Chloride; Zosyn; Vancomycin; Coumadin



Possible Abraxane side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-18

Patient:

Reactions: Weight Decreased, Thrombosis, Tachycardia, Headache, Tricuspid Valve Incompetence, Pericardial Effusion, Hot Flush, Amenorrhoea, Dyspepsia, Upper Respiratory Tract Infection, Oedema Peripheral, Temperature Intolerance, Cough, Epistaxis, Anaemia, Oral Infection, Convulsion, Insomnia, Vision Blurred, Neutropenia, Jaundice, Cardiac Tamponade, Conjunctivitis, Bone Pain, Pelvic Pain, Abdominal Pain Upper, Fatigue, Neuropathy Peripheral, Skin Discolouration, Chest Pain, Oedema, Depression, Gastrooesophageal Reflux Disease, Thrombocytopenia, Lymphoedema, Pharyngitis, Decreased Appetite, Renal Failure Acute, Vomiting, Nausea, Heart Valve Incompetence, Palmar-Plantar Erythrodysaesthesia Syndrome, Rhinorrhoea, Scotoma, Rash, Mucosal Inflammation, Anxiety, Dysgeusia, Diarrhoea, Breast Abscess, Alopecia, Hypertension, Infection, Influenza Like Illness

Drug(s) suspected as cause:
Abraxane
    Dosage: 150 milligram/sq. meter

Bevacizumab
    Dosage: 10 milligram/kilogram

Gemcitabine
    Dosage: 1500 milligram/sq. meter



Possible Abraxane side effects in 56 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-29

Patient: 56 year old female

Reactions: Vomiting, Neurological Decompensation, Anaemia, Mental Status Changes, Headache, Incontinence, Urosepsis, Neutropenia, Hydrocephalus

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: auc2
    Start date: 2007-01-01
    End date: 2007-01-01

Abraxane
    Dosage: 100 milligram/sq. meter
    Indication: Breast Cancer Metastatic
    Start date: 2007-01-01
    End date: 2007-01-01

Carboplatin
    Dosage: auc6, 1hour infusion on day 1
    Indication: Breast Cancer Metastatic
    Start date: 2007-01-01



Possible Abraxane side effects in female

Reported by a physician from United States on 2012-03-20

Patient: female, weighing 74.0 kg (162.8 pounds)

Reactions: Sepsis, Neutropenia, Stevens-Johnson Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: MOI-Stir; Gravol TAB; Lactulose; Senokot; Atarax; Zometa; Fragmin; Nystatin; Polyethylene Glycol; Glycerin; Hydromorphone HCL; Ativan; Neupogen



Possible Abraxane side effects in female

Reported by a physician from United States on 2012-03-13

Patient: female, weighing 74.5 kg (163.9 pounds)

Reactions: Neutropenia

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: Ativan; Flexeril; Zofran; Oxycodone HCL; Xanax; Compazine; Valtrex



Possible Abraxane side effects in female

Reported by a physician from United States on 2012-03-09

Patient: female, weighing 74.0 kg (162.8 pounds)

Reactions: Sepsis, Neutropenia, Stevens-Johnson Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Abraxane

Other drugs received by patient: Hydromorphone HCL; Zometa; Polyethylene Glycol; Lactulose; Gravol TAB; Glycerin; Neupogen; Atarax; Antibiotics; Senokot; Nystatin; MOI-Stir



Possible Abraxane side effects in female

Reported by a physician from United States on 2012-01-12

Patient: female, weighing 104.0 kg (228.8 pounds)

Reactions: Neutropenic Infection, Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Gemcitabine
    Dosage: 800 milligram/sq. meter
    Start date: 2011-12-15
    End date: 2011-12-22

Gemcitabine
    Dosage: 1000 milligram/sq. meter
    Indication: Adenocarcinoma Pancreas
    Start date: 2011-11-10

Abraxane
    Dosage: 125 milligram/sq. meter
    Indication: Adenocarcinoma Pancreas
    Start date: 2011-11-10

Abraxane
    Dosage: 100 milligram/sq. meter
    Start date: 2011-12-15
    End date: 2011-12-22

Other drugs received by patient: Spironolactone; Ceftriaxone; Sodium Chloride; Pantoprazole; Gabapentin; Insulin; Humalog; Norepinephrine Bitartrate; Lidocaine; Alteplase; Omeprazole; Kayexalate; Dextrose; Sodium Bicarbonate; Fluid; Levothyroxine Sodium; Keflex; Nystatin; Hydromorphone HCL; Cosyntropin; Ciprofloxacin; Lovenox; Fentanyl; Lasix; Glipizide; Bicarbonate; Furosemide; Magnesium Oxide; Vancomycin; Platelets; Metronidazole; Cephalexin; Whole Blood; Fluconazole; Dexamethasone TAB; Cefepime; Heparin



Possible Abraxane side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-06

Patient: female, weighing 104.0 kg (228.8 pounds)

Reactions: Neutropenic Infection, Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 125 milligram/sq. meter
    Indication: Adenocarcinoma Pancreas
    Start date: 2011-11-10

Abraxane
    Dosage: 100 milligram/sq. meter
    Start date: 2011-12-15
    End date: 2011-12-22

Gemcitabine
    Dosage: 800 milligram/sq. meter
    Start date: 2011-12-15
    End date: 2011-12-22

Gemcitabine
    Dosage: 1000 milligram/sq. meter
    Indication: Adenocarcinoma Pancreas
    Start date: 2011-11-10

Other drugs received by patient: Cephalexin; Gabapentin; Glipizide; Levothyroxine Sodium; Ceftriaxone; Vancomycin; Dextrose; Sodium Chloride; Norepinephrine Bitartrate; Fluconazole; Furosemide; Nystatin; Alteplase; Lovenox; Bicarbonate; Sodium Bicarbonate; Cefepime; Metronidazole; Insulin; Fluid; Pantoprazole; Hydromorphone HCL; Cosyntropin; Kayexalate; Spironolactone; Platelets; Dexamethasone; Lidocaine; Omeprazole; Whole Blood; Keflex; Fentanyl; Lasix; Magnesium Oxide; Humalog; Heparin



Possible Abraxane side effects in female

Reported by a physician from United States on 2011-12-30

Patient: female, weighing 68.0 kg (149.7 pounds)

Reactions: Abdominal Pain, Gingival Abscess, Pyrexia, Loss of Consciousness, Abdominal Discomfort, Herpes Simplex, Dyspepsia, Immunosuppression, Back Pain, Dysphagia, Coronary Artery Disease, Nasal Congestion, Renal Cyst, Cardiomyopathy, Dysphonia, Insomnia, Ocular Icterus, Neutropenia, Vocal Cord Polyp, Jaundice, Pain, Chills, Hepatic Lesion, Haemorrhoidal Haemorrhage, Death, Myalgia, Bone Loss, Fatigue, Left Ventricular Dysfunction, Anhedonia, Neck Pain, Injury, Gastrooesophageal Reflux Disease, Decreased Appetite, Pain in JAW, Vulvovaginal Mycotic Infection, Bone Lesion, Rash, Anxiety, Dysgeusia, Agranulocytosis, Cardiac Failure, Osteonecrosis of JAW, Oral Disorder, Asthenia, Leukopenia, Disability, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zometa
    Dosage: unk ukn, every 4 weeks
    Start date: 2006-04-01
    End date: 2007-06-01

Abraxane
    Dosage: 170 mg, unk

Other drugs received by patient: Ativan; Faslodex; Coumadin; Taxotere; Fentanyl Citrate; Femara; Oxycodone HCL; Neupogen; Wellbutrin; Humira; Acyclovir; Percocet; Aromasin; Xanax; Restoril; Radiation; Chemotherapeutics; Compazine; Zofran; Neulasta; Decadron



Possible Abraxane side effects in

Reported by a health professional (non-physician/pharmacist) from Singapore on 2011-12-21

Patient:

Reactions: Vomiting, Nausea, Anaemia, Febrile Neutropenia, Hypocalcaemia, Neutropenia, Decreased Appetite

Drug(s) suspected as cause:
Abraxane



Possible Abraxane side effects in 64 year old female

Reported by a physician from United States on 2011-12-02

Patient: 64 year old female

Reactions: Haemoglobin Decreased, Weight Decreased, Diarrhoea, Oral Candidiasis, Hypotension, Dehydration, Neutropenia, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 60 milligram/sq. meter
    Indication: Breast Cancer
    Start date: 2011-03-03
    End date: 2011-04-19

Bevacizumab / Placebo
    Indication: Breast Cancer
    Start date: 2011-03-03
    End date: 2011-06-14

Abraxane
    Dosage: 186 milligram
    Indication: Breast Cancer
    Start date: 2011-06-28

Cyclophosphamide
    Dosage: 600 milligram/sq. meter
    Indication: Breast Cancer
    Start date: 2011-03-03
    End date: 2011-04-19

Neulasta
    Dosage: 6 milligram
    Indication: Breast Cancer
    Start date: 2011-03-03
    End date: 2011-04-20

Other drugs received by patient: Prbc; Hydration; Nystatin



Possible Abraxane side effects in 67 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-15

Patient: 67 year old female, weighing 48.0 kg (105.6 pounds)

Reactions: Diarrhoea, Nausea, Urinary Tract Infection, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 144mg weekly iv
    Indication: Breast Cancer
    Start date: 2011-09-02
    End date: 2011-11-01

Carboplatin
    Dosage: 404mg every 3 wks 9/2, 9/27, 10/25/11
    Indication: Breast Cancer

Other drugs received by patient: M.v.i.; Aspirin; Asmanex Twisthaler; Spiriva; Ranitidine; Alendronate Sodium; Imodium; Metamucil-2; Compazine; Fioricet; Potassium Chloride; Kytril; Albuterol; Ativan



Possible Abraxane side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-10

Patient: male, weighing 71.3 kg (156.8 pounds)

Reactions: Dehydration, Acute Respiratory Distress Syndrome, Neutropenia, Cerebral Haemorrhage, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aspirin
    Dosage: 81 milligram
    Administration route: Oral

Abraxane
    Indication: Bladder Cancer

Other drugs received by patient: Platelets; RED Blood Cells



Possible Abraxane side effects in

Reported by a physician from United States on 2011-10-27

Patient:

Reactions: Nausea, Anaemia, Febrile Neutropenia, Peripheral Sensory Neuropathy, Fatigue, Alopecia, Sepsis, Neutropenia, Thrombocytopenia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Abraxane
    Dosage: 100,125, or 150mg/m2
    Indication: Pancreatic Carcinoma

Gemcitabine
    Dosage: 1000 milligram/sq. meter



Possible Abraxane side effects in

Reported by a health professional (non-physician/pharmacist) from Canada on 2011-10-19

Patient:

Reactions: Dysphagia, Stomatitis, Neutropenia

Drug(s) suspected as cause:
Cisplatin

Abraxane

Fluorouracil



Possible Abraxane side effects in 63 year old female

Reported by a physician from United States on 2011-10-11

Patient: 63 year old female, weighing 89.2 kg (196.2 pounds)

Reactions: White Blood Cell Count Decreased, Dyspnoea, Anaemia, Muscular Weakness, Myalgia, Fatigue, Renal Failure, Diarrhoea, Proteinuria, Platelet Count Decreased, Hypocalcaemia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abraxane
    Dosage: 232 milligram
    Start date: 2010-03-04

Gemcitabine Hydrochloride
    Dosage: 1860 milligram
    Start date: 2010-03-04

Gemcitabine Hydrochloride
    Dosage: 1860 milligram
    Start date: 2010-11-11
    End date: 2010-11-18

Abraxane
    Dosage: 232 milligram
    Start date: 2010-11-11
    End date: 2010-11-18

Bevacizumab
    Dosage: 1368 milligram
    Start date: 2010-03-04
    End date: 2010-10-21



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