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Abilify (Aripiprazole) - Neuroleptic Malignant Syndrome - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Neuroleptic Malignant Syndrome ()

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Abilify (Aripiprazole) where reactions include neuroleptic malignant syndrome. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of    Next >>

Possible Abilify side effects in 31 year old male

Reported by a physician from Japan on 2012-08-27

Patient: 31 year old male, weighing 59.0 kg (129.8 pounds)

Reactions: Eosinophilic Pneumonia, Pulmonary Alveolar Haemorrhage, Acute Respiratory Distress Syndrome, Neuroleptic Malignant Syndrome, Pneumonia Staphylococcal

Adverse event resulted in: death

Drug(s) suspected as cause:
Methotrimeprazine Maleate

Levotomin
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-01
    End date: 2012-06-29

Rohypnol
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-01
    End date: 2012-06-29

Abilify
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-23
    End date: 2012-06-29

Risperdal
    Dosage: 4mg: 4jun-11jun12(8days) 2mg:12jun-29jun12(18days)
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-04
    End date: 2012-06-29

Other drugs received by patient: Diazepam; Promethazine HCL; Miya-BM



Possible Abilify side effects in 31 year old male

Reported by a pharmacist from Japan on 2012-08-27

Patient: 31 year old male, weighing 59.0 kg (129.8 pounds)

Reactions: Eosinophilic Pneumonia, Pulmonary Alveolar Haemorrhage, Acute Respiratory Distress Syndrome, Neuroleptic Malignant Syndrome, Pneumonia Staphylococcal

Adverse event resulted in: death

Drug(s) suspected as cause:
Methotrimeprazine Maleate

Abilify
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-23
    End date: 2012-06-29

Risperdal
    Dosage: 4mg: 4jun-11jun12(8days) 2mg:12jun-29jun12(18days)
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-04
    End date: 2012-06-29

Rohypnol
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-01
    End date: 2012-06-29

Levotomin
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-01
    End date: 2012-06-29

Other drugs received by patient: Diazepam; Promethazine HCL; Miya-BM



Possible Abilify side effects in 49 year old male

Reported by a consumer/non-health professional from France on 2012-08-23

Patient: 49 year old male

Reactions: Cytolytic Hepatitis, Neuroleptic Malignant Syndrome, Drug Withdrawal Syndrome

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Alprazolam
    Administration route: Oral
    End date: 2012-07-01

Mirtazapine
    Dosage: formulation: tabs
    Administration route: Oral

Abilify
    Dosage: until jul12
    Administration route: Oral
    Indication: Schizophrenia

Mianserin HCL
    End date: 2012-07-01



Possible Abilify side effects in 31 year old male

Reported by a consumer/non-health professional from Japan on 2012-08-16

Patient: 31 year old male, weighing 59.0 kg (129.8 pounds)

Reactions: Eosinophilic Pneumonia, Pulmonary Alveolar Haemorrhage, Acute Respiratory Distress Syndrome, Pneumonia Staphylococcal, Neuroleptic Malignant Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Risperdal
    Dosage: 4mg: 4jun-11jun12(8days) 2mg:12jun-29jun12(18days)
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-04
    End date: 2012-06-29

Abilify
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-23
    End date: 2012-06-29

Levotomin
    Administration route: Oral
    Start date: 2012-06-01

Methotrimeprazine Maleate

Rohypnol
    Start date: 2012-06-01

Other drugs received by patient: Promethazine HCL; Miya-BM; Diazepam



Possible Abilify side effects in 60 year old male

Reported by a consumer/non-health professional from Japan on 2012-08-13

Patient: 60 year old male, weighing 53.0 kg (116.6 pounds)

Reactions: Pneumonia, Drug Ineffective, Hypoglycaemia, Hepatic Failure, Neuroleptic Malignant Syndrome

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Abilify
    Dosage: 27jun07-2jul07;12mg,6days.03-jul-11jul 24mg/day.15mg 12jul-7aug:30mg, 3week 6days. also 6mg
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-06-27
    End date: 2007-08-07

Levotomin
    Dosage: 50 mg 4 weeks 1day. 31jul07-7aug07;dose increased to 150 mg on 31jul07, 1week 1day. tabs 100mg 1jn07
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-07-02
    End date: 2007-08-07

Other drugs received by patient: Ringers Solution, Lactated; Biperiden Lactate; Doral; Haloperidol; Amoxicillin; Biperiden Hydrochloride TAB; Flunitrazepam; Maintenance Medium 5; Silece; Cefotiam Hydrochloride



Possible Abilify side effects in 31 year old male

Reported by a pharmacist from Japan on 2012-08-03

Patient: 31 year old male

Reactions: Eosinophilic Pneumonia, Haemorrhage, Interstitial Lung Disease, Neuroleptic Malignant Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Abilify
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-23
    End date: 2012-07-02

Risperdal
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-29
    End date: 2012-07-02

Risperdal
    Administration route: Oral
    Start date: 2012-06-04
    End date: 2012-06-29

Haloperidol
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-01
    End date: 2012-07-02



Possible Abilify side effects in 31 year old male

Reported by a consumer/non-health professional from Japan on 2012-08-02

Patient: 31 year old male, weighing 59.0 kg (129.8 pounds)

Reactions: Eosinophilic Pneumonia, Pulmonary Alveolar Haemorrhage, Acute Respiratory Distress Syndrome, Pneumonia Staphylococcal, Neuroleptic Malignant Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Risperdal
    Dosage: 4mg: 4jun-11jun12(8days) 2mg:12jun-29jun12(18days)
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-04
    End date: 2012-06-29

Abilify
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2012-06-23
    End date: 2012-06-29

Levotomin
    Administration route: Oral
    Start date: 2012-06-01

Other drugs received by patient: Miya-BM; Promethazine HCL; Rohypnol; Diazepam



Possible Abilify side effects in 47 year old male

Reported by a consumer/non-health professional from Japan on 2012-07-16

Patient: 47 year old male, weighing 79.0 kg (173.8 pounds)

Reactions: Neuroleptic Malignant Syndrome, Withdrawal Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Aripiprazole
    Dosage: inj
    Indication: Schizophrenia
    Start date: 2011-12-12
    End date: 2012-04-02

Abilify
    Dosage: 07aug07-26sep11;12mg,27sep11-02oct11;24mg,03oct11-12apr12;193d
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-08-07
    End date: 2012-04-12

Placebo

Other drugs received by patient: Diovan; Famotidine; Cleanal; Mucosta; Olopatadine HCL; Onon; Livostin; Calslot; Risperdal



Possible Abilify side effects in 49 year old female

Reported by a consumer/non-health professional from Japan on 2012-07-04

Patient: 49 year old female, weighing 45.0 kg (99.0 pounds)

Reactions: Neuroleptic Malignant Syndrome, Posture Abnormal, Salivary Hypersecretion

Drug(s) suspected as cause:
Abilify

Other drugs received by patient: Biperiden Hydrochloride TAB; Clonazepam; Promazine Hydrochloride; Flunitrazepam; Trialam; Sennoside



Possible Abilify side effects in 49 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-25

Patient: 49 year old female, weighing 45.0 kg (99.0 pounds)

Reactions: Blood Creatine Phosphokinase Increased, Alanine Aminotransferase Increased, Pain, Blood Lactate Dehydrogenase Increased, Posture Abnormal, Pyrexia, Aspartate Aminotransferase Increased, Psychiatric Symptom, Salivary Hypersecretion, Neuroleptic Malignant Syndrome

Drug(s) suspected as cause:
Abilify

Other drugs received by patient: Flunitrazepam; Trialam; Clonazepam; Biperiden Hydrochloride TAB; Promazine Hydrochloride; Sennoside



Possible Abilify side effects in 49 year old female

Reported by a consumer/non-health professional from Japan on 2012-06-10

Patient: 49 year old female

Reactions: Blood Creatine Phosphokinase Increased, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Pain, Posture Abnormal, Pyrexia, Aspartate Aminotransferase Increased, Psychiatric Symptom, Neuroleptic Malignant Syndrome, Salivary Hypersecretion

Drug(s) suspected as cause:
Abilify

Other drugs received by patient: Trialam; Flunitrazepam; Clonazepam; Promazine Hydrochloride; Sennoside; Biperiden Hydrochloride TAB



Possible Abilify side effects in 45 year old male

Reported by a consumer/non-health professional from Japan on 2012-06-01

Patient: 45 year old male, weighing 86.0 kg (189.2 pounds)

Reactions: Pneumonia, Renal Impairment, Ileus, Respiratory Failure, Neuroleptic Malignant Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Abilify
    Dosage: 3mg:05jul-07jul11, 6mg:08jul-11jul11, 9mg:12jul-19jul11.
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-07-05
    End date: 2011-07-19

Cremin
    Dosage: granules
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 1996-10-01
    End date: 2011-07-19

Fludecasin
    Indication: Schizophrenia
    Start date: 2004-05-25
    End date: 2011-06-20

Promethazine HCL
    Administration route: Oral
    Indication: Parkinsonism
    Start date: 1996-10-01
    End date: 2011-07-19

Pentona
    Administration route: Oral
    Indication: Parkinsonism
    Start date: 1996-10-01
    End date: 2011-07-19

Akineton
    Administration route: Oral
    Indication: Parkinsonism
    Start date: 1996-10-01
    End date: 2011-07-19

Symmetrel
    Dosage: granules
    Administration route: Oral
    Indication: Parkinsonism
    Start date: 1996-10-01
    End date: 2011-07-19

Other drugs received by patient: Lasix; Trichlormethiazide; Diazepam



Possible Abilify side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-05-07

Patient: 47 year old male, weighing 79.0 kg (173.8 pounds)

Reactions: Withdrawal Syndrome, Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Pelex
    Dosage: reg1:1g,tid;oral;13apr2012-15apr2012(3d);granules reg2:3gm,daily;oral 20apr2012-unk
    Administration route: Oral
    Indication: Nasopharyngitis
    Start date: 2012-04-13

Calslot
    Dosage: tabs
    Administration route: Oral
    Indication: Hypertension
    Start date: 2011-12-26

Medicon
    Dosage: tabs reg1:15mg,tid;oral;13apr2012-15apr2012 reg2:45mg,daily;oral;20apr2012-unk
    Administration route: Oral
    Indication: Nasopharyngitis
    Start date: 2012-04-13

Brotizolam
    Dosage: reg 2-0.5mg-15apr12-ong
    Administration route: Oral
    Indication: Insomnia
    Start date: 2012-04-09
    End date: 2012-04-15

Aripiprazole
    Dosage: inj
    Indication: Schizophrenia
    Start date: 2011-12-12
    End date: 2012-04-02

Potassium Chloride
    Indication: Neuroleptic Malignant Syndrome
    Start date: 2012-04-13
    End date: 2012-04-15

Tathion
    Dosage: injection
    Indication: Neuroleptic Malignant Syndrome
    Start date: 2012-04-13
    End date: 2012-04-15

Diovan
    Dosage: tabs
    Administration route: Oral
    Indication: Hypertension
    Start date: 2011-05-09

Abilify
    Dosage: 07aug07-26sep11;12mg,27sep11-02oct11;24mg,03oct11-12apr12;193d
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-08-07
    End date: 2012-04-12

NEO-Minophagen C
    Indication: Neuroleptic Malignant Syndrome
    Start date: 2012-04-13
    End date: 2012-04-15

Dantrium
    Dosage: reg 1 reg 2-16apr12-ong
    Administration route: Oral
    Indication: Neuroleptic Malignant Syndrome
    Start date: 2012-04-13
    End date: 2012-04-15

Placebo

Cefoperazone Sodium + Sulbactam Sodium
    Indication: Neuroleptic Malignant Syndrome
    Start date: 2012-04-13
    End date: 2012-04-15

Mucosta
    Dosage: tab
    Administration route: Oral
    Indication: Gastritis
    Start date: 2006-03-22
    End date: 2012-04-15

Other drugs received by patient: Livostin; Risperdal; Famotidine; Olopatadine HCL; Onon; Cleanal



Possible Abilify side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-03-13

Patient: female

Reactions: Cogwheel Rigidity, Confusional State, Blood Creatine Phosphokinase Increased, Urinary Tract Infection, Tachycardia, Neuroleptic Malignant Syndrome, Pyrexia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Trimeprazine Tartrate
    Dosage: 10 drops in the evening
    Administration route: Oral
    Start date: 2012-02-02

Clozapine
    Dosage: 37.5 mg, daily
    Administration route: Oral
    Indication: Psychiatric Symptom
    Start date: 2012-01-31
    End date: 2012-02-07

Abilify
    Administration route: Oral
    Start date: 2012-01-17
    End date: 2012-01-30

Risperdal Consta
    Start date: 2011-12-27
    End date: 2012-02-03

Other drugs received by patient: Trihexyphenidyl Hydrochloride; Alprazolam; Risperdal; Imovane; Atarax



Possible Abilify side effects in 85 year old male

Reported by a physician from Poland on 2012-01-13

Patient: 85 year old male, weighing 85.0 kg (187.0 pounds)

Reactions: Death, Neuroleptic Malignant Syndrome

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Depakene
    Indication: Schizophrenia, Paranoid Type
    Start date: 2011-11-03
    End date: 2011-12-10

Abilify
    Dosage: 15 mg in the morning and 15 mg in the evening last dose:15mg in mrng
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    Start date: 2011-11-03
    End date: 2011-12-10

Lamotrigine
    Indication: Schizophrenia, Paranoid Type
    Start date: 2011-11-03
    End date: 2011-12-10



Possible Abilify side effects in 85 year old male

Reported by a physician from Poland on 2011-12-20

Patient: 85 year old male, weighing 85.0 kg (187.0 pounds)

Reactions: Death, Neuroleptic Malignant Syndrome

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Abilify
    Dosage: 15 mg in the morning and 15 mg in the evening last dose:15mg in mrng
    Administration route: Oral
    Indication: Schizophrenia, Paranoid Type
    Start date: 2011-11-03
    End date: 2011-12-10

Depakene
    Indication: Schizophrenia, Paranoid Type
    Start date: 2011-11-03
    End date: 2011-12-10

Lamotrigine
    Indication: Schizophrenia, Paranoid Type
    Start date: 2011-11-03
    End date: 2011-12-10



Possible Abilify side effects in 17 year old male

Reported by a pharmacist from United States on 2011-12-16

Patient: 17 year old male

Reactions: Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abilify



Possible Abilify side effects in male

Reported by a consumer/non-health professional from United States on 2011-12-16

Patient: male

Reactions: Neuroleptic Malignant Syndrome

Drug(s) suspected as cause:
Abilify
    Dosage: duration:2 weeks approx.
    Indication: Schizophrenia

Prolixin Decanoate
    Dosage: duration:2 weeks approx.
    Indication: Schizophrenia



Possible Abilify side effects in 19 year old male

Reported by a consumer/non-health professional from United States on 2011-12-16

Patient: 19 year old male

Reactions: Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyprexa

Abilify

Effexor



Possible Abilify side effects in 17 year old male

Reported by a physician from United States on 2011-12-16

Patient: 17 year old male

Reactions: Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Depakote
    Indication: Bipolar I Disorder

Haloprogin
    Indication: Bipolar I Disorder

Lithium Carbonate
    Indication: Bipolar I Disorder

Abilify
    Administration route: Oral
    Indication: Bipolar I Disorder



Possible Abilify side effects in 5 year old male

Reported by a consumer/non-health professional from United States on 2011-12-16

Patient: 5 year old male

Reactions: Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abilify

Other drugs received by patient: Clonidine



Possible Abilify side effects in 31 year old male

Reported by a consumer/non-health professional from United States on 2011-12-16

Patient: 31 year old male

Reactions: Neuroleptic Malignant Syndrome

Drug(s) suspected as cause:
Abilify



Possible Abilify side effects in 5 year old male

Reported by a consumer/non-health professional from United States on 2011-12-16

Patient: 5 year old male

Reactions: Neuroleptic Malignant Syndrome

Drug(s) suspected as cause:
Abilify



Possible Abilify side effects in female

Reported by a consumer/non-health professional from United States on 2011-12-16

Patient: female

Reactions: Neuroleptic Malignant Syndrome

Drug(s) suspected as cause:
Cymbalta

Abilify

Lamictal



Possible Abilify side effects in 4 year old

Reported by a consumer/non-health professional from United States on 2011-12-16

Patient: 4 year old

Reactions: Neuroleptic Malignant Syndrome

Drug(s) suspected as cause:
Abilify



Possible Abilify side effects in 32 year old male

Reported by a consumer/non-health professional from Denmark on 2011-12-12

Patient: 32 year old male

Reactions: Electrocardiogram ST Segment Depression, Bedridden, Suicidal Ideation, Overdose, C-Reactive Protein Increased, Decubitus Ulcer, Neuroleptic Malignant Syndrome, Hallucination, Oxygen Saturation Decreased, Pneumonia, Toxicity To Various Agents, Electrocardiogram QRS Complex Shortened, Psychotic Disorder, Hallucinations, Mixed, Hypophagia, Fluid Intake Reduced, Depressed Level of Consciousness

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Abilify
    Dosage: interrupted and restarted with 15mg
    Administration route: Oral
    Indication: Depression

Clozapine
    Dosage: interrrupted and restarted with 200 mg
    Administration route: Oral
    Indication: Mental Disorder

Duloxetine Hydrochloride
    Dosage: gastro resistant capsule hard
    Administration route: Oral
    Indication: Depression

Cymbalta
    Dosage: gastro resistant capsule, hard interrupted and restarted with 60mg
    Administration route: Oral
    Indication: Depression

Other drugs received by patient: Pantoprazole Sodium; Buprenex; Metoprolol Succinate; Simvastatin



Possible Abilify side effects in 39 year old male

Reported by a physician from United Kingdom on 2011-11-21

Patient: 39 year old male

Reactions: Blood Creatine Phosphokinase Increased, Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Valproate Sodium
    Indication: Schizophrenia, Paranoid Type
    Start date: 2008-02-05
    End date: 2008-03-02

Clozapine
    Indication: Schizophrenia, Paranoid Type
    End date: 2007-12-17

Lithium Carbonate
    Indication: Schizophrenia, Paranoid Type
    Start date: 2008-03-06
    End date: 2008-06-18

Quetiapine Fumarate
    Dosage: at bedtime
    Indication: Schizophrenia, Paranoid Type
    Start date: 2008-01-01
    End date: 2008-01-08

Valproate Sodium
    Start date: 2008-03-06

Depixol
    Indication: Schizophrenia, Paranoid Type
    End date: 2007-12-17

Abilify
    Indication: Schizophrenia, Paranoid Type
    Start date: 2008-02-18
    End date: 2008-02-23

Valproate Sodium
    Start date: 2008-03-03
    End date: 2008-03-05

Chlorpromazine
    Indication: Schizophrenia, Paranoid Type
    End date: 2007-12-17

Clozapine
    Start date: 2008-01-29
    End date: 2008-02-05

Procyclidine Hydrochloride 2MG TAB
    Indication: Schizophrenia, Paranoid Type
    End date: 2007-12-17

Clozapine
    Start date: 2008-03-26

Other drugs received by patient: Lorazepam; Antibiotics; Hyoscine Hydrobromide



Possible Abilify side effects in 8 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-14

Patient: 8 year old male, weighing 24.5 kg (53.9 pounds)

Reactions: Neuroleptic Malignant Syndrome, Salivary Hypersecretion, Swollen Tongue, Tremor

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Abilify



Possible Abilify side effects in 68 year old

Reported by a consumer/non-health professional from Germany on 2011-11-11

Patient: 68 year old , weighing 120.0 kg (264.0 pounds)

Reactions: Neuroleptic Malignant Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Abilify



Possible Abilify side effects in 39 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2011-11-10

Patient: 39 year old male

Reactions: Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Hyoscine HBR HYT
    Indication: Salivary Hypersecretion

Clozapine
    Indication: Schizophrenia, Paranoid Type
    Start date: 2008-01-29
    End date: 2008-02-05

Abilify
    Dosage: 10mg in the morning
    Indication: Schizophrenia, Paranoid Type
    Start date: 2008-02-18
    End date: 2008-02-23

Quetiapine
    Dosage: 50mg at night
    Indication: Schizophrenia, Paranoid Type
    Start date: 2008-01-01
    End date: 2008-01-08

Valproate Sodium

Clozapine
    Start date: 2008-03-26

Other drugs received by patient: Lorazepam; Chlorpromazine; Procyclidine Hydrochloride 2MG TAB; Diazepam; Depakote; Clozapine; Depixol; Lithium



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