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Share your experience: submit a drug review
Below are Methotrexate reviews, ratings, comments submitted by patients and caregivers. Based on a total of 5 ratings/reviews, Methotrexate has an overall score of 7.40. The effectiveness score is 8.80 and the side effect score is 7.20. The scores are on ten point scale: 10 - best, 1 - worst. This information is not vetted and should not be cosidered as clinical evidence. | | Methotrexate review by 64 year old female patient | | | Rating |
| Overall rating: | |           |
| Effectiveness: | | Considerably Effective |
| Side effects: | | No Side Effects | | | Treatment Info |
| Condition / reason: | | Rheumatoid Arthritis |
| Dosage & duration: | | 20 mg. taken 1 x week for the period of 2 years to present |
| Other conditions: | | none |
| Other drugs taken: | | Remicade | | | Reported Results |
| Benefits: | | The combination of weekly 20mg. Methotrexate with an infusion (at the doctor's office) of Remicade has almost completely controlled my rheumatoid arthritis.
I have had no further joint damage, and the initial symptoms of extreme fatigue and pain in the small joints of my hands, wrists, feet and ankles has abated. |
| Side effects: | | None that I am aware of |
| Comments: | | I was diagnosed with rheumatoid arthritis about two years ago and began treatment with a combination of Remicade (infused once every eight weeks over a period of about 2 hours in my doctor's office) and Methotrexate 20 mg. once a week. I take 8 tablets every Friday, 2.r mg. each. I have had no negative side effects from either medication. |
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| | Methotrexate review by 58 year old female patient | | | Rating |
| Overall rating: | |           |
| Effectiveness: | | Considerably Effective |
| Side effects: | | Severe Side Effects | | | Treatment Info |
| Condition / reason: | | psoraitic arthritis |
| Dosage & duration: | | 6 tabs taken daily for the period of 4 years |
| Other conditions: | | psoriasis |
| Other drugs taken: | | none | | | Reported Results |
| Benefits: | | the treatment masked the psoriasis and what was considered arthritis |
| Side effects: | | increasing all over body pain |
| Comments: | | I started with 4 tabs and increased to 6 as the all over body pain increased and then they were going to put me on prednisone. I opted to turn to homeopathic treatment and weaned off the methotrexate. The all over body pain went completely away but the psoriasis was exacerbated. I'd rather have that than not be able to walk or move. |
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| | Methotrexate review by care giver of 12 year old female patient | | | Rating |
| Overall rating: | |           |
| Effectiveness: | | Considerably Effective |
| Side effects: | | Mild Side Effects | | | Treatment Info |
| Condition / reason: | | juvenile rheumatoid arthritis |
| Dosage & duration: | | 15 mg taken once a week for the period of 1 year |
| Other conditions: | | none |
| Other drugs taken: | | prednisone, naprosyn | | | Reported Results |
| Benefits: | | Methotrexate significantly reduced my daughter's arthritis symptoms, allowing her to resume a normal, active life without joint pain. After being treated with this drug, she has remained symptom free for several years now. She did not have to progress to more expensive arthritis drugs since she responded well to methotrexate. |
| Side effects: | | Thinning hair, weight gain. We don't know if these were due to the methotrexate or other drugs she was on. |
| Comments: | | She took the dosage once a week for about a year, and eventually was weaned off of all her arthritis related drugs. |
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| | Methotrexate review by 54 year old female patient | | | Rating |
| Overall rating: | |           |
| Effectiveness: | | Highly Effective |
| Side effects: | | No Side Effects | | | Treatment Info |
| Condition / reason: | | Rheumatoid Arthritis |
| Dosage & duration: | | 25mg taken weekly for the period of Ongoing |
| Other conditions: | | Hypothyroidism, hypercholesterolemia |
| Other drugs taken: | | Synthroid, Ezetrol, Folic Acid | | | Reported Results |
| Benefits: | | Control of joint inflammation |
| Side effects: | | None. |
| Comments: | | The methotrexate is administered by subcutaneous injection (self-administered) 25mgs once per week. I have been taking methotexate for approximately 5 years. Foe the first 4 years I took the same dose orally, but it eventually beacme less effective so I switched to subcutaneous injection. It has been extremely effective at controlling the symptoms of rheumatoid arthritis and I feel 95% normal. |
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| | Methotrexate review by 45 year old female patient | | | Rating |
| Overall rating: | |           |
| Effectiveness: | | Highly Effective |
| Side effects: | | Severe Side Effects | | | Treatment Info |
| Condition / reason: | | psoriasis |
| Dosage & duration: | | 30 mg taken 1xweel for the period of 1 year |
| Other conditions: | | none |
| Other drugs taken: | | none | | | Reported Results |
| Benefits: | | 95% cleared chronic severe psoriasis from scalp to feet. Extremely easy to administer. |
| Side effects: | | nausea, fatigue, elevated white blood cells, low side of normal liver lab results. |
| Comments: | | took 10 mg every 3 hours for a total dose of 30 mg/wk. Initially started with 15 mg/wk but became tolerant and had to move up to 30 mg/wk |
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