Had effexor reaction after 75mg. What is the risk from half that dose?

Question

30 minutes after taking 1st dose of 75 mg tablet of effexor my skin started getting a prickly burning sensation all over my skin which increased for about 2 hours. I kept thinking I was going to get a rash but l never did. Also I was anxious, got migraine, was nauseated and my eyes dialated.  The symptoms peaked in about 2-3 hours but the symptoms lasted 2 days. I wasnt able to eat til the 3rd day.  The Dr. told me to skip a day and then take 1/2 tab but I did not because I was afraid it would make me sick again.  I was wondering if you think Iits likely I will also have symptoms at 1/2 tab. I fearful of taking even 1//2 of the dose. I was really sick. Almost went to hospital. Probably should of.          Thank you,

Answer 1

If this was an allergic reaction (it doesn't necessarily sound like one), then a half dose is likely to still produce symptoms. If it was a nervous system side effect, which sounds more likely, then half a dose may still produce some adverse effects, although probably less intense. Perhaps a quarter of the original dose could be a more prudent re-starting point -- but make sure to discuss any dose adjustments with your doctor.