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What is the reason for the 24hr expiration time on Plegisol when bicarbonate is added?

Standard for an entered container or instability? Other?
asked Jun 25, 2012 by anonymous
edited Jun 26, 2012 by bigbird

1 Answer

0 votes
Sodium bicarbonate must be added just prior to administration due to its inherent instability with other components.
The function of the Sodium bicarbonate  is to regulate pH.

Packaging and temperature can also affect the expiration period.  

http://www.druglib.com/druginfo/plegisol/description_pharmacology/
answered Jun 27, 2012 by anonymous