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What is the reason for the 24hr expiration time on Plegisol when bicarbonate is added?
Standard for an entered container or instability? Other?
expiration
asked
Jun 25, 2012
by
anonymous
edited
Jun 26, 2012
by
bigbird
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Sodium bicarbonate must be added just prior to administration due to its inherent instability with other components.
The function of the Sodium bicarbonate is to regulate pH.
Packaging and temperature can also affect the expiration period.
http://www.druglib.com/druginfo/plegisol/description_pharmacology/
answered
Jun 27, 2012
by
anonymous