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Zyflo (Zileuton) - Summary

 


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ZYFLO SUMMARY

ZYFLO®
(zileuton tablets)

Zileuton is an orally active inhibitor of 5-lipoxygenase, the enzyme that catalyzes the formation of leukotrienes from arachidonic acid.

ZYFLO is indicated for the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older.


See all Zyflo indications & dosage >>

ZYFLO NEWS HIGHLIGHTS

Media Articles Related to Zyflo (Zileuton)

Researchers link C-section babies to asthma risk (Reuters)
Source: Y! Health Asthma News [2008.12.01]

Asthma inhalers to go 'green' on Dec. 31 (AP)
Source: Y! Health Asthma News [2008.12.01]

Experts Urge Change In Asthma Management
Source: Respiratory / Asthma News From Medical News Today [2008.11.29]

The Brussels Declaration: The Need For Change In Asthma Management
Source: Respiratory / Asthma News From Medical News Today [2008.11.27]

Obesity, lack of exercise reported in asthmatics (Reuters)
Source: Y! Health Asthma News [2008.11.25]

more >>

Published Studies Related to Zyflo (Zileuton)

Efficacy of zileuton controlled-release tablets administered twice daily in the treatment of moderate persistent asthma: a 3-month randomized controlled study. [2007.08]

Clinical pattern of zileuton-associated liver injury: results of a 12-month study in patients with chronic asthma. [2007]

Effects of 5-lipoxygenase inhibitor zileuton on airway responses to inhaled swine house dust in healthy subjects. [2006.02]

Zileuton added to low-dose inhaled beclomethasone for the treatment of moderate to severe persistent asthma. [2007.06]

Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton. [2007.06]

more >>

Clinical Trials Related to Zyflo (Zileuton)

Zileuton and Exhaled Nitric Oxide in Asthmatics [Completed]

Assessment of PFT, Safety, and PK of Zileuton Injection in Asthma Patients [Completed]

Zileuton CR vs Placebo in Poorly Controlled Asthma Patients on Moderate Dose ICS [Terminated]

Safety Study of Zileuton Injection in Patients With Asthma [Completed]

Zileuton in Preventing Lung Cancer in Patients With Bronchial Dysplasia [Active, not recruiting]

more >>

Page last updated: 2008-12-01

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